"Signal Transduction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
Descriptor ID |
D015398
|
MeSH Number(s) |
G02.111.820 G04.835
|
Concept/Terms |
Signal Transduction- Signal Transduction
- Signal Transductions
- Transduction, Signal
- Transductions, Signal
- Signal Transduction Systems
- Signal Transduction System
- System, Signal Transduction
- Systems, Signal Transduction
Signal Pathways- Signal Pathways
- Pathway, Signal
- Pathways, Signal
- Signal Pathway
Signal Transduction Pathways- Signal Transduction Pathways
- Pathway, Signal Transduction
- Pathways, Signal Transduction
- Signal Transduction Pathway
Receptor-Mediated Signal Transduction- Receptor-Mediated Signal Transduction
- Receptor-Mediated Signal Transductions
- Signal Transduction, Receptor-Mediated
- Signal Transductions, Receptor-Mediated
- Receptor Mediated Signal Transduction
|
Below are MeSH descriptors whose meaning is more general than "Signal Transduction".
Below are MeSH descriptors whose meaning is more specific than "Signal Transduction".
This graph shows the total number of publications written about "Signal Transduction" by people in this website by year, and whether "Signal Transduction" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1996 | 0 | 1 | 1 |
1997 | 0 | 1 | 1 |
1998 | 1 | 1 | 2 |
1999 | 1 | 3 | 4 |
2000 | 3 | 1 | 4 |
2001 | 1 | 3 | 4 |
2002 | 0 | 1 | 1 |
2003 | 1 | 2 | 3 |
2004 | 2 | 3 | 5 |
2005 | 1 | 2 | 3 |
2006 | 2 | 3 | 5 |
2007 | 0 | 6 | 6 |
2008 | 4 | 7 | 11 |
2009 | 5 | 9 | 14 |
2010 | 1 | 2 | 3 |
2011 | 3 | 5 | 8 |
2012 | 8 | 6 | 14 |
2013 | 1 | 7 | 8 |
2014 | 8 | 14 | 22 |
2015 | 5 | 11 | 16 |
2016 | 5 | 10 | 15 |
2017 | 6 | 12 | 18 |
2018 | 1 | 11 | 12 |
2019 | 7 | 17 | 24 |
2020 | 2 | 6 | 8 |
2021 | 2 | 10 | 12 |
2022 | 2 | 6 | 8 |
2023 | 0 | 6 | 6 |
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click here.
Below are the most recent publications written about "Signal Transduction" by people in Profiles.
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Activation of the cGAS/STING Axis in Genome-Damaged Hematopoietic Cells Does Not Impact Blood Cell Formation or Leukemogenesis. Cancer Res. 2023 09 01; 83(17):2858-2872.
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A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis. Sci Signal. 2023 08 15; 16(798):eade6737.
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A non-canonical function of Arabidopsis ERECTA proteins and a role of the SWI3B subunit of the SWI/SNF chromatin remodeling complex in gibberellin signaling. Plant J. 2023 08; 115(3):788-802.
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Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes. Commun Biol. 2023 04 15; 6(1):418.
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Ageing-associated changes in transcriptional elongation influence longevity. Nature. 2023 Apr; 616(7958):814-821.
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Tissue-specific macrophages: how they develop and choreograph tissue biology. Nat Rev Immunol. 2023 09; 23(9):563-579.
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Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors. Cell Death Dis. 2022 Sep 20; 13(9):806.
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Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data. Nat Commun. 2022 06 09; 13(1):3224.
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Mature neutrophils and a NF-?B-to-IFN transition determine the unifying disease recovery dynamics in COVID-19. Cell Rep Med. 2022 06 21; 3(6):100652.
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The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway. Front Immunol. 2022; 13:856230.