"Cellular Senescence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
| Descriptor ID |
D016922
|
| MeSH Number(s) |
G04.043
|
| Concept/Terms |
Cell Aging- Cell Aging
- Cellular Ageing
- Ageing, Cellular
- Aging, Cell
- Senescence, Replicative
- Cellular Aging
- Aging, Cellular
- Replicative Senescence
- Cell Ageing
- Ageing, Cell
Senescence-Associated Secretory Phenotype- Senescence-Associated Secretory Phenotype
- Phenotype, Senescence-Associated Secretory
- Secretory Phenotype, Senescence-Associated
- Senescence Associated Secretory Phenotype
|
Below are MeSH descriptors whose meaning is more general than "Cellular Senescence".
Below are MeSH descriptors whose meaning is more specific than "Cellular Senescence".
This graph shows the total number of publications written about "Cellular Senescence" by people in this website by year, and whether "Cellular Senescence" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 3 | 4 |
| 2016 | 3 | 2 | 5 |
| 2017 | 1 | 1 | 2 |
| 2018 | 3 | 3 | 6 |
| 2019 | 0 | 1 | 1 |
| 2020 | 3 | 1 | 4 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cellular Senescence" by people in Profiles.
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Biallelic variants in CRIPT cause a Rothmund-Thomson-like syndrome with increased cellular senescence. Genet Med. 2023 Jul; 25(7):100836.
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Principles of the Molecular and Cellular Mechanisms of Aging. J Invest Dermatol. 2021 04; 141(4S):951-960.
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ARDD 2020: from aging mechanisms to interventions. Aging (Albany NY). 2020 12 30; 12(24):24484-24503.
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DNA Damage Response and Metabolic Reprogramming in Health and Disease. Trends Genet. 2020 10; 36(10):777-791.
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Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1. J Steroid Biochem Mol Biol. 2020 07; 201:105689.
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Senescence-Associated Metabolomic Phenotype in Primary and iPSC-Derived Mesenchymal Stromal Cells. Stem Cell Reports. 2020 02 11; 14(2):201-209.
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DNA damage responses in ageing. Open Biol. 2019 11 29; 9(11):190168.
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Extension of longevity and reduction of inflammation is ovarian-dependent, but germ cell-independent in post-reproductive female mice. Geroscience. 2019 02; 41(1):25-38.
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The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells. Haematologica. 2019 01; 104(1):35-46.
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Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice. Clin Epigenetics. 2018; 10:67.
MeSH information
