"Telomere Shortening" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.
| Descriptor ID |
D059506
|
| MeSH Number(s) |
G02.111.225.940 G04.043.630 G05.226.940
|
| Concept/Terms |
Telomere Shortening- Telomere Shortening
- Shortening, Telomere
- Shortenings, Telomere
- Telomere Shortenings
|
Below are MeSH descriptors whose meaning is more general than "Telomere Shortening".
Below are MeSH descriptors whose meaning is more specific than "Telomere Shortening".
This graph shows the total number of publications written about "Telomere Shortening" by people in this website by year, and whether "Telomere Shortening" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Telomere Shortening" by people in Profiles.
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Biallelic variants in YRDC cause a developmental disorder with progeroid features. Hum Genet. 2021 Dec; 140(12):1679-1693.
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Epigenetic Clocks Are Not Accelerated in COVID-19 Patients. Int J Mol Sci. 2021 Aug 27; 22(17).
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Comparison of flow-FISH and MM-qPCR telomere length assessment techniques for the screening of telomeropathies. Ann N Y Acad Sci. 2020 04; 1466(1):93-103.
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Recurrent somatic mutations are rare in patients with cryptic dyskeratosis congenita. Leukemia. 2018 08; 32(8):1762-1767.
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Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease. Pharmacol Res. 2016 09; 111:422-433.
MeSH information
