"Genomic Imprinting" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The variable phenotypic expression of a GENE depending on whether it is of paternal or maternal origin, which is a function of the DNA METHYLATION pattern. Imprinted regions are observed to be more methylated and less transcriptionally active. (Segen, Dictionary of Modern Medicine, 1992)
| Descriptor ID |
D018392
|
| MeSH Number(s) |
G05.308.203.500
|
| Concept/Terms |
Genomic Imprinting- Genomic Imprinting
- Imprinting, Genomic
- Parental Imprinting
- Imprinting, Parental
- Imprinting, Genetic
- Genetic Imprinting
|
Below are MeSH descriptors whose meaning is more general than "Genomic Imprinting".
Below are MeSH descriptors whose meaning is more specific than "Genomic Imprinting".
This graph shows the total number of publications written about "Genomic Imprinting" by people in this website by year, and whether "Genomic Imprinting" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2010 | 3 | 1 | 4 |
| 2011 | 3 | 1 | 4 |
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 2 | 2 | 4 |
| 2016 | 4 | 2 | 6 |
| 2017 | 2 | 1 | 3 |
| 2018 | 3 | 1 | 4 |
| 2019 | 2 | 1 | 3 |
| 2020 | 5 | 2 | 7 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genomic Imprinting" by people in Profiles.
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Trans-acting genetic variants causing multilocus imprinting disturbance (MLID): common mechanisms and consequences. Clin Epigenetics. 2022 03 16; 14(1):41.
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Unusual deletion of the maternal 11p15 allele in Beckwith-Wiedemann syndrome with an impact on both imprinting domains. Clin Epigenetics. 2021 02 04; 13(1):30.
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Biallelic PADI6 variants cause multilocus imprinting disturbances and miscarriages in the same family. Eur J Hum Genet. 2021 04; 29(4):575-580.
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Molecular characterization of temple syndrome families with 14q32 epimutations. Eur J Med Genet. 2020 Dec; 63(12):104077.
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Need for a precise molecular diagnosis in Beckwith-Wiedemann and Silver-Russell syndrome: what has to be considered and why it is important. J Mol Med (Berl). 2020 10; 98(10):1447-1455.
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Heterogeneous phenotypes in families with duplications of the paternal allele within the imprinting center 1 (H19/IGF2:TSS-DMR) in 11p15.5. Clin Genet. 2020 10; 98(4):418-419.
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Paternal 132 bp deletion affecting KCNQ1OT1 in 11p15.5 is associated with growth retardation but does not affect imprinting. J Med Genet. 2021 03; 58(3):173-176.
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Frequency of KCNQ1 variants causing loss of methylation of Imprinting Centre 2 in Beckwith-Wiedemann syndrome. Clin Epigenetics. 2020 05 11; 12(1):63.
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Disturbed genomic imprinting and its relevance for human reproduction: causes and clinical consequences. Hum Reprod Update. 2020 02 28; 26(2):197-213.
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Molecular and Clinical Opposite Findings in 11p15.5 Associated Imprinting Disorders: Characterization of Basic Mechanisms to Improve Clinical Management. Int J Mol Sci. 2019 Aug 28; 20(17).
MeSH information
