"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
Descriptor ID |
D044127
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MeSH Number(s) |
G05.308.203
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Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
|
Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2009 | 2 | 0 | 2 |
2010 | 2 | 0 | 2 |
2011 | 1 | 1 | 2 |
2012 | 3 | 1 | 4 |
2013 | 0 | 1 | 1 |
2014 | 2 | 1 | 3 |
2015 | 8 | 4 | 12 |
2016 | 9 | 6 | 15 |
2017 | 3 | 4 | 7 |
2018 | 5 | 2 | 7 |
2019 | 1 | 7 | 8 |
2020 | 4 | 2 | 6 |
2021 | 5 | 5 | 10 |
2022 | 1 | 2 | 3 |
2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
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Culture expansion of CAR T cells results in aberrant DNA methylation that is associated with adverse clinical outcome. Leukemia. 2023 09; 37(9):1868-1878.
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Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer's disease. Alzheimers Res Ther. 2023 05 06; 15(1):92.
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Emerging mitochondrial signaling mechanisms in cardio-oncology: beyond oxidative stress. Am J Physiol Heart Circ Physiol. 2022 10 01; 323(4):H702-H720.
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Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation. BMC Biol. 2022 06 15; 20(1):141.
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Therapeutical interference with the epigenetic landscape of germ cell tumors: a comparative drug study and new mechanistical insights. Clin Epigenetics. 2022 01 07; 14(1):5.
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MLL1 is required for maintenance of intestinal stem cells. PLoS Genet. 2021 12; 17(12):e1009250.
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Epigenetic Priming of Bladder Cancer Cells With Decitabine Increases Cytotoxicity of Human EGFR and CD44v6 CAR Engineered T-Cells. Front Immunol. 2021; 12:782448.
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Epigenome-wide association study of alcohol use disorder in five brain regions. Neuropsychopharmacology. 2022 03; 47(4):832-839.
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Transmission of trained immunity and heterologous resistance to infections across generations. Nat Immunol. 2021 11; 22(11):1382-1390.
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Epigenetic Clocks Are Not Accelerated in COVID-19 Patients. Int J Mol Sci. 2021 Aug 27; 22(17).