"Up-Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Descriptor ID |
D015854
|
MeSH Number(s) |
G02.111.905 G05.308.850 G07.690.773.998
|
Concept/Terms |
Up-Regulation- Up-Regulation
- Up Regulation
- Upregulation
- Up-Regulation (Physiology)
|
Below are MeSH descriptors whose meaning is more general than "Up-Regulation".
Below are MeSH descriptors whose meaning is more specific than "Up-Regulation".
This graph shows the total number of publications written about "Up-Regulation" by people in this website by year, and whether "Up-Regulation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2004 | 0 | 2 | 2 |
2005 | 0 | 3 | 3 |
2006 | 1 | 5 | 6 |
2007 | 0 | 2 | 2 |
2008 | 1 | 2 | 3 |
2009 | 1 | 1 | 2 |
2010 | 0 | 2 | 2 |
2011 | 0 | 1 | 1 |
2012 | 0 | 3 | 3 |
2013 | 0 | 4 | 4 |
2015 | 0 | 2 | 2 |
2017 | 0 | 3 | 3 |
2018 | 0 | 4 | 4 |
2019 | 0 | 4 | 4 |
2020 | 1 | 3 | 4 |
2021 | 1 | 1 | 2 |
2022 | 0 | 2 | 2 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Up-Regulation" by people in Profiles.
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Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors. Mol Cancer. 2023 08 15; 22(1):136.
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Wounding response in Porifera (sponges) activates ancestral signaling cascades involved in animal healing, regeneration, and cancer. Sci Rep. 2022 01 25; 12(1):1307.
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The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates. Biomaterials. 2022 03; 282:121389.
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Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology. EMBO J. 2021 12 15; 40(24):e108662.
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Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients. Genome Med. 2021 01 13; 13(1):7.
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Msx1 deficiency interacts with hypoxia and induces a morphogenetic regulation during mouse lip development. Development. 2020 06 24; 147(21).
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CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms. Br J Cancer. 2020 08; 123(3):378-391.
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Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy. Oncoimmunology. 2020; 9(1):1730538.
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Carotenoids are used as regulators for membrane fluidity by Staphylococcus xylosus. Sci Rep. 2020 01 15; 10(1):330.
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?-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32. Cell Rep. 2019 Sep 03; 28(10):2659-2672.e6.