Next Generation Sequencing Competence Network

Next Generation Sequencing Competence Network

e.g. CCGA
(min 2 characters)

Karl Köhrer

Prof.
Heinrich-Heine-University Duesseldorf
Genomics & Transcriptomics Laboratory
Universitätsstraße 1, 40225 Düsseldorf, Germany
Düsseldorf 40225
+49 221 8113165
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Jaeger BAS, Krawczyk N, Japp AS, Honisch E, K?hrer K, Scheuring S, Petzsch P, Neubauer H, Volkmer AK, Esposito I, Ruckh?berle E, Niederacher D, Fehm T. Whole Exome Analysis to Select Targeted Therapies for Patients with Metastatic Breast Cancer - A Feasibility Study. Geburtshilfe Frauenheilkd. 2023 Sep; 83(9):1138-1147. PMID: 37706056; PMCID: PMC10497348.
      Citations:    Fields:    
    2. Arlt C, Wachtmeister T, K?hrer K, Stich B. Affordable, accurate and unbiased RNA sequencing by manual library miniaturization: A case study in barley. Plant Biotechnol J. 2023 Aug 18. PMID: 37593840.
      Citations:    Fields:    Translation:Animals
    3. Sankaranarayanan S, Haag C, Petzsch P, K?hrer K, Matuszynska A, Zarnack K, Feldbr?gge M. The mRNA stability factor Khd4 defines a specific mRNA regulon for membrane trafficking in the pathogen Ustilago maydis. Proc Natl Acad Sci U S A. 2023 08 22; 120(34):e2301731120. PMID: 37590419; PMCID: PMC10450656.
      Citations: 2     Fields:    Translation:Cells
    4. Wolf SD, Ehlting C, M?ller-Dott S, Poschmann G, Petzsch P, Lautwein T, Wang S, Helm B, Schilling M, Saez-Rodriguez J, Vucur M, St?hler K, K?hrer K, Tacke F, Dooley S, Klingm?ller U, Luedde T, Bode JG. Hepatocytes reprogram liver macrophages involving control of TGF-? activation, influencing liver regeneration and injury. Hepatol Commun. 2023 08 01; 7(8). PMID: 37486964; PMCID: PMC10368377.
      Citations:    Fields:    Translation:AnimalsCells
    5. Trombly G, Said AM, Kudin AP, Peeva V, Altm?ller J, Becker K, K?hrer K, Zsurka G, Kunz WS. The Fate of Oxidative Strand Breaks in Mitochondrial DNA. Antioxidants (Basel). 2023 May 12; 12(5). PMID: 37237953; PMCID: PMC10215735.
      Citations: 1     
    6. Rafii P, Seibel C, Weitz HT, Ettich J, Minafra AR, Petzsch P, Lang A, Floss DM, Behnke K, K?hrer K, Moll JM, Scheller J. Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes. Commun Biol. 2023 04 15; 6(1):418. PMID: 37061565; PMCID: PMC10105715.
      Citations: 1     Translation:HumansAnimalsCells
    7. Houwaart T, Scholz S, Pollock NR, Palmer WH, Kichula KM, Strelow D, Le DB, Belick D, H?lse L, Lautwein T, Wachtmeister T, Wollenweber TE, Henrich B, K?hrer K, Parham P, Guethlein LA, Dilthey AT, Norman PJ. Complete sequences of six major histocompatibility complex haplotypes, including all the major MHC class II structures. HLA. 2023 07; 102(1):28-43. PMID: 36932816.
      Citations: 6     Fields:    Translation:Humans
    8. Schrenk C, Bollmann LM, Haist C, Bister A, Wiek C, Wecker M, Roth D, Petzsch P, K?hrer K, Hamacher A, Hanenberg H, Fluegen G, Kassack MU. Synergistic Interaction of the Class IIa HDAC Inhibitor CHDI0039 with Bortezomib in Head and Neck Cancer Cells. Int J Mol Sci. 2023 Mar 14; 24(6). PMID: 36982651; PMCID: PMC10056166.
      Citations:    Fields:    Translation:HumansCells
    9. Yildiz I, Gross M, Moser D, Petzsch P, K?hrer K, Zeier J. N-hydroxypipecolic acid induces systemic acquired resistance and transcriptional reprogramming via TGA transcription factors. Plant Cell Environ. 2023 06; 46(6):1900-1920. PMID: 36790086.
      Citations: 2     Fields:    Translation:Animals
    10. Rohbeck E, Niersmann C, K?hrer K, Wachtmeister T, Roden M, Eckel J, Romacho T. Positive allosteric GABAA receptor modulation counteracts lipotoxicity-induced gene expression changes in hepatocytes in vitro. Front Physiol. 2023; 14:1106075. PMID: 36860523; PMCID: PMC9968943.
      Citations:    
    11. Kralj J, Pernar Kovac M, Dabelic S, Polancec DS, Wachtmeister T, K?hrer K, Brozovic A. Transcriptome analysis of newly established carboplatin-resistant ovarian cancer cell model reveals genes shared by drug resistance and drug-induced EMT. Br J Cancer. 2023 03; 128(7):1344-1359. PMID: 36717670; PMCID: PMC10050213.
      Citations: 2     Fields:    Translation:HumansCells
    12. Br?ning AKE, Schiefer JL, Fuchs PC, Petzsch P, K?hrer K, Suschek CV, St?rmer EK, Opl?nder C. Low-Dose Blue Light (420 nm) Reduces Metabolic Activity and Inhibits Proliferation of Human Dermal Fibroblasts. Life (Basel). 2023 Jan 25; 13(2). PMID: 36836688; PMCID: PMC9965217.
      Citations: 1     
    13. Burmeister A, Stephan A, Alves Avelar LA, M?ller MR, Seiwert A, H?fmann S, Fischer F, Torres-Gomez H, Hoffmann MJ, Niegisch G, Bremmer F, Petzsch P, K?hrer K, Albers P, Kurz T, Skowron MA, Nettersheim D. Establishment and Evaluation of Dual HDAC/BET Inhibitors as Therapeutic Options for Germ Cell Tumors and Other Urological Malignancies. Mol Cancer Ther. 2022 Nov 03; 21(11):1674-1688. PMID: 35999659.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    14. Gruchot J, Lein F, Lewen I, Reiche L, Weyers V, Petzsch P, G?ttle P, K?hrer K, Hartung HP, K?ry P, Kremer D. Siponimod Modulates the Reaction of Microglial Cells to Pro-Inflammatory Stimulation. Int J Mol Sci. 2022 Oct 31; 23(21). PMID: 36362063; PMCID: PMC9655930.
      Citations: 3     Fields:    Translation:HumansCells
    15. Bottermann K, Kalfhues L, Nederlof R, Hemmers A, Leitner LM, Oenarto V, Nemmer J, Pfeffer M, Raje V, Deenen R, Petzsch P, Zabri H, K?hrer K, Reichert AS, Grandoch M, Fischer JW, Herebian D, Stegbauer J, Harris TE, G?decke A. Cardiomyocyte p38 MAPKa suppresses a heart-adipose tissue-neutrophil crosstalk in heart failure development. Basic Res Cardiol. 2022 10 07; 117(1):48. PMID: 36205817; PMCID: PMC9542472.
      Citations: 1     Fields:    Translation:AnimalsCells
    16. Mass E, Skowron MA, Eul K, Stephan A, Ludwig GF, Wakileh GA, Bister A, S?hngen C, Raba K, Petzsch P, Poschmann G, Kuffour EO, Degrandi D, Ali S, Wiek C, Hanenberg H, M?nk C, St?hler K, K?hrer K, Nettersheim D. Profiling the 3D interaction between germ cell tumors and microenvironmental cells at the transcriptome and secretome level. Mol Oncol. 2022 09; 16(17):3107-3127. PMID: 35811571; PMCID: PMC9441004.
      Citations: 5     Fields:    Translation:HumansCells
    17. Nederlof R, Reidel S, Spychala A, G?decke S, Heinen A, Lautwein T, Petzsch P, K?hrer K, G?decke A. Insulin-Like Growth Factor 1 Attenuates the Pro-Inflammatory Phenotype of Neutrophils in Myocardial Infarction. Front Immunol. 2022; 13:908023. PMID: 35911749; PMCID: PMC9334797.
      Citations: 5     Fields:    Translation:HumansCells
    18. Li L, Pahl M, Bendt F, Schauss A, Leung PC, Wang CC, Koch K, Tigges J, Fan X, Fritsche E, Klose J, H?benthal U, J?ngst C, Petzsch P, K?hrer K. Application of the adverse outcome pathway concept for investigating developmental neurotoxicity potential of Chinese herbal medicines by using human neural progenitor cells in vitro. Cell Biol Toxicol. 2023 02; 39(1):319-343. PMID: 35701726; PMCID: PMC10042984.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    19. Jaguva Vasudevan AA, Hoffmann MJ, Poschmann G, Petzsch P, Wiek C, St?hler K, K?hrer K, Schulz WA, Niegisch G. Proteomic and transcriptomic profiles of human urothelial cancer cells with histone deacetylase 5 overexpression. Sci Data. 2022 05 27; 9(1):240. PMID: 35624179; PMCID: PMC9142574.
      Citations: 3     Fields:    Translation:HumansCells
    20. Wammers M, Schupp AK, Bode JG, Ehlting C, Wolf S, Graf D, Deenen R, K?hrer K, H?ussinger D. Author Correction: Reprogramming of pro-inflammatory human macrophages to an anti-inflammatory phenotype by bile acids. Sci Rep. 2022 May 04; 12(1):7255. PMID: 35508550; PMCID: PMC9068820.
      Citations:    Fields:    
    21. Zhao M, Larsen PK, Skerra J, Islam H, Kirschning C, Weighardt H, Kalinke U, Yang X, Ali S, Richter L, Sch?fer V, Schliehe-Diecks J, Frank M, Qi J, Wachtmeister T, Alter C, Huang A, Bhatia S, K?hrer K, Kalscheuer R, Uhrberg M, Scheu S. The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway. Front Immunol. 2022; 13:856230. PMID: 35464417; PMCID: PMC9024221.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    22. Dietrich M, Hecker C, Martin E, Langui D, Gliem M, Stankoff B, Lubetzki C, Gruchot J, G?ttle P, Issberner A, Nasiri M, Ramseier P, Beerli C, Tisserand S, Beckmann N, Shimshek D, Petzsch P, Akbar D, Levkau B, Stark H, K?hrer K, Hartung HP, K?ry P, Meuth SG, Bigaud M, Zalc B, Albrecht P. Increased Remyelination and Proregenerative Microglia Under Siponimod Therapy in Mechanistic Models. Neurol Neuroimmunol Neuroinflamm. 2022 05; 9(3). PMID: 35354603; PMCID: PMC8969301.
      Citations: 15     Fields:    Translation:AnimalsCells
    23. Milenkovic D, Declerck K, Corral-Jara KF, Berghe WV, Rodriguez-Mateos A, Lucosz M, Istas G, Sansone R, Deenen R, K?hrer K, Altschmied J, Haendeler J, Kelm M, Heiss C. Flavanol Consumption in Healthy Men Preserves Integrity of Immunological-Endothelial Barrier Cell Functions: Nutri(epi)genomic Analysis. Mol Nutr Food Res. 2022 Nov; 66(21):e2100991. PMID: 35094491.
      Citations: 4     Fields:    Translation:HumansAnimals
    24. M?ller MR, Burmeister A, Skowron MA, Stephan A, Bremmer F, Wakileh GA, Petzsch P, K?hrer K, Albers P, Nettersheim D. Therapeutical interference with the epigenetic landscape of germ cell tumors: a comparative drug study and new mechanistical insights. Clin Epigenetics. 2022 01 07; 14(1):5. PMID: 34996497; PMCID: PMC8742467.
      Citations: 8     Fields:    Translation:HumansCells
    25. Tigges J, Masjosthusmann S, Schmuck K, Bendt F, Petzsch P, Koch K, Fritsche E, Klose J, H?benthal U, K?hrer K. Corrigendum to TBBPA Targets Converging Key Events of Human Oligodendrocyte Development Resulting in Two Novel AOPs. ALTEX. 2022; 39(2):339. PMID: 35413128.
      Citations:    Fields:    
    26. Grunewald CM, Haist C, Petzsch P, Bister A, Wiek C, Scheckenbach K, Hanenberg H, K?nig C, N??ner E, K?hrer K, Niegisch G, Hoffmann MJ. Epigenetic Priming of Bladder Cancer Cells With Decitabine Increases Cytotoxicity of Human EGFR and CD44v6 CAR Engineered T-Cells. Front Immunol. 2021; 12:782448. PMID: 34868059; PMCID: PMC8637820.
      Citations: 11     Fields:    Translation:HumansCells
    27. Mann-N?ttel R, Ali S, Petzsch P, K?hrer K, Alferink J, Scheu S. The transcription factor reservoir and chromatin landscape in activated plasmacytoid dendritic cells. BMC Genom Data. 2021 09 20; 22(1):37. PMID: 34544361; PMCID: PMC8454182.
      Citations: 2     Fields:    Translation:AnimalsCells
    28. Pavic G, Petzsch P, Jansen R, Raba K, Rychlik N, Simiantonakis I, K?ry P, G?ttle P, K?hrer K, Hartung HP, Meuth SG, Jander S, Gliem M. Microglia contributes to remyelination in cerebral but not spinal cord ischemia. Glia. 2021 11; 69(11):2739-2751. PMID: 34390590.
      Citations: 4     Fields:    Translation:HumansCells
    29. Jostes S, Bremmer F, Fronhoffs F, Funke K, Altevogt P, Kristiansen G, Schorle H, Skowron MA, Becker TK, Kurz L, Wakileh GA, M?ller MR, Burmeister A, Lenz T, Stefanski A, St?hler K, Petzsch P, K?hrer K, Albers P, Nettersheim D. The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas. Mol Oncol. 2022 02; 16(4):982-1008. PMID: 34293822; PMCID: PMC8847992.
      Citations: 7     Fields:    Translation:Humans
    30. Nicklas W, Benga L, Lautwein T, Verbarg S, Gougoula C, Engelhardt E, Benten WPM, K?hrer K, Sager M, Christensen H. Rodentibacter haemolyticus sp. nov. isolated from laboratory rodents. Int J Syst Evol Microbiol. 2021 Aug; 71(8). PMID: 34379582.
      Citations: 1     Fields:    Translation:AnimalsCells
    31. Yildiz I, Mantz M, Hartmann M, Zeier T, Kessel J, Thurow C, Gatz C, Petzsch P, K?hrer K, Zeier J. The mobile SAR signal N-hydroxypipecolic acid induces NPR1-dependent transcriptional reprogramming and immune priming. Plant Physiol. 2021 07 06; 186(3):1679-1705. PMID: 33871649; PMCID: PMC8260123.
      Citations: 18     Fields:    Translation:AnimalsCells
    32. Dieterich C, Hesse J, Owenier C, Lautwein T, Zalfen R, Weber JF, Ding Z, Alter C, Lang A, Grandoch M, Gerdes N, Fischer JW, Klau GW, K?hrer K, Schrader J. Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted murine heart. Elife. 2021 06 21; 10. PMID: 34152268; PMCID: PMC8216715.
      Citations: 26     Fields:    Translation:AnimalsCells
    33. Hehlgans T, Sorg UR, K?pper N, Mock J, Tersteegen A, Petzsch P, K?hrer K, Pfeffer K. Lymphotoxin-?-receptor (LT?R) signaling on hepatocytes is required for liver regeneration after partial hepatectomy. Biol Chem. 2021 08 26; 402(9):1147-1154. PMID: 34087963.
      Citations:    Fields:    Translation:AnimalsCells
    34. Bormann F, J?ger P, Geyh S, Twarock S, Cadeddu RP, Rabes P, Koch A, Maus U, Hesper T, Zilkens C, Rautenberg C, K?hrer K, Petzsch P, Wieczorek D, Betz B, Surowy H, Hildebrandt B, Germing U, Kobbe G, Haas R, Schroeder T. Acute myeloid leukemia-induced functional inhibition of healthy CD34+ hematopoietic stem and progenitor cells. Stem Cells. 2021 09; 39(9):1270-1284. PMID: 34013984.
      Citations: 4     Fields:    Translation:HumansCells
    35. Virgen-Slane R, Dunay IR, Ware CF, Tersteegen A, Sorg UR, Helle M, Petzsch P, K?hrer K, Degrandi D, Pfeffer K. Lymphotoxin ? Receptor: a Crucial Role in Innate and Adaptive Immune Responses against Toxoplasma gondii. Infect Immun. 2021 05 17; 89(6). PMID: 33753412; PMCID: PMC8316152.
      Citations: 1     Fields:    Translation:Animals
    36. Kruse CPS, Bezrutczyk M, Z?llner NR, Hartwig T, Lautwein T, K?hrer K, Frommer WB, Kim JY. Evidence for phloem loading via the abaxial bundle sheath cells in maize leaves. Plant Cell. 2021 05 05; 33(3):531-547. PMID: 33955497; PMCID: PMC8136869.
      Citations: 38     Fields:    Translation:Animals
    37. Liaskou E, Hov JR, Karlsen TH, Beuers U, Verheij J, Ferreira-Gonzalez S, Hirschfield G, Forbes SJ, Schramm C, Nierhoff D, Fickert P, Fuchs CD, Trauner M, Mallm JP, Vogel M, Heikenwalder M, Reich M, Spomer L, Klindt C, Fuchs K, Stindt J, Deutschmann K, H?hne J, Esposito I, Garc?a-Beccaria M, Gabernet G, Nahnsen S, Schoonjans K, Lautwein T, K?hrer K, H?ussinger D, Luedde T, Keitel V. Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis. J Hepatol. 2021 09; 75(3):634-646. PMID: 33872692.
      Citations: 18     Fields:    Translation:AnimalsCells
    38. Eder T, Grebien F, Deepe GS, Rattei T, Shima K, Kaufhold I, K?ding N, Schmidt N, Ogunsulire IM, Deenen R, K?hrer K, Friedrich D, Isay SE, Klinger M, Richer BC, G?nther UL, Rupp J. Regulation of the Mitochondrion-Fatty Acid Axis for the Metabolic Reprogramming of Chlamydia trachomatis during Treatment with ?-Lactam Antimicrobials. mBio. 2021 03 30; 12(2). PMID: 33785629; PMCID: PMC8092193.
      Citations: 6     Fields:    Translation:HumansCells
    39. Whongsiri P, Goering W, Lautwein T, Hader C, Schulz WA, Niegisch G, K?hrer K, Hoffmann MJ. Many Different LINE-1 Retroelements Are Activated in Bladder Cancer. Int J Mol Sci. 2020 Dec 11; 21(24). PMID: 33322422; PMCID: PMC7763009.
      Citations: 5     Fields:    Translation:HumansCells
    40. Dasa SSK, French BA, Straub T, Nave J, Bouvain P, Akbarzadeh M, Kistner J, Ding Z, Marzoq A, Stepanow S, Becker K, Hesse J, K?hrer K, Fl?gel U, Ahmadian MR, Schrader J, Temme S. MRI-based molecular imaging of epicardium-derived stromal cells (EpiSC) by peptide-mediated active targeting. Sci Rep. 2020 12 10; 10(1):21669. PMID: 33303866; PMCID: PMC7728754.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    41. Henrich B, Hammerlage S, Scharf S, Haberhausen D, Peitzmann L, Fiori PL, Spergser J, Pfeffer K, Dilthey AT, F?rnkranz U, K?hrer K. Characterisation of mobile genetic elements in Mycoplasma hominis with the description of ICEHo-II, a variant mycoplasma integrative and conjugative element. Mob DNA. 2020 Nov 07; 11(1):30. PMID: 33292499; PMCID: PMC7648426.
      Citations: 3     
    42. Rautenberg C, Germing U, Stepanow S, Lauseker M, Geyh S, Fan M, Haas R, Kobbe G, Schroeder T, K?hrer K, J?ger PS. Influence of somatic mutations and pretransplant strategies in patients allografted for myelodysplastic syndrome or secondary acute myeloid leukemia. Am J Hematol. 2021 01; 96(1):E15-E17. PMID: 33017477.
      Citations: 5     Fields:    Translation:Humans
    43. Auer F, Raboso-Gallego J, De Las Rivas J, Hauer J, Vicente-Due?as C, Janssen S, Oldenburg M, Gonz?lez-Herrero I, Casado-Garc?a A, Isidro-Hern?ndez M, Westhoff P, Pandyra AA, Hein D, G?ssling KL, Alonso-L?pez D, Bhatia S, Garc?a-Criado FJ, Garc?a-Cenador MB, Weber APM, K?hrer K, Fischer U, S?nchez-Garc?a I, Borkhardt A. An intact gut microbiome protects genetically predisposed mice against leukemia. Blood. 2020 10 29; 136(18):2003-2017. PMID: 32911536; PMCID: PMC7694022.
      Citations: 44     Fields:    Translation:Animals
    44. Benga L, Benten PM, Engelhardt E, Hueber B, Nicklas W, Christensen H, Sager M, K?hrer K. Differentiation Among Rodentibacter Species Based on 16S-23S rRNA Internal Transcribed Spacer Analysis. Comp Med. 2020 12 01; 70(6):487-491. PMID: 33121574; PMCID: PMC7754199.
      Citations: 1     Fields:    Translation:AnimalsCells
    45. Tigges J, Masjosthusmann S, Schmuck K, Bendt F, Petzsch P, Koch K, Fritsche E, Klose J, H?benthal U, K?hrer K. TBBPA targets converging key events of human oligodendrocyte development resulting in two novel AOPs ALTEX. 2021; 38(2):215-234. PMID: 33099281.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    46. Bremmer F, Calaminus G, Skowron MA, Vermeulen M, Winkelhausen A, Becker TK, Petzsch P, Sch?nberger S, K?hrer K, Albers P, Nettersheim D. CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms. Br J Cancer. 2020 08; 123(3):378-391. PMID: 32418994; PMCID: PMC7403155.
      Citations: 20     Fields:    Translation:HumansCells
    47. Lang A, Whongsiri P, Yilmaz M, Lautwein T, Petzsch P, Greife A, G?nes C, K?hrer K, Niegisch G, Hoffmann M, Schulz WA. Knockdown of UTX/KDM6A Enriches Precursor Cell Populations in Urothelial Cell Cultures and Cell Lines. Cancers (Basel). 2020 Apr 21; 12(4). PMID: 32326336; PMCID: PMC7226239.
      Citations: 2     
    48. Brenig K, Grube L, Schwarzl?nder M, K?hrer K, St?hler K, Poschmann G. The Proteomic Landscape of Cysteine Oxidation That Underpins Retinoic Acid-Induced Neuronal Differentiation. J Proteome Res. 2020 05 01; 19(5):1923-1940. PMID: 32202429.
      Citations: 7     Fields:    Translation:Cells
    49. Owenier C, Hesse J, Alter C, Ding Z, Marzoq A, Petzsch P, K?hrer K, Schrader J. Novel technique for the simultaneous isolation of cardiac fibroblasts and epicardial stromal cells from the infarcted murine heart. Cardiovasc Res. 2020 04 01; 116(5):1047-1058. PMID: 31504244.
      Citations: 5     Fields:    Translation:AnimalsCells
    50. Weighardt H, Schumak B, Merches K, Schiavi A, Steinwachs S, Teichweyde N, F?rster I, Hochrath K, Ventura N, Petzsch P, K?hrer K, Esser C. AHR Signaling Dampens Inflammatory Signature in Neonatal Skin ?d T Cells. Int J Mol Sci. 2020 Mar 24; 21(6). PMID: 32213963; PMCID: PMC7139545.
      Citations: 8     Fields:    Translation:AnimalsCells
    51. Lang J, Bohn P, Bhat H, Jastrow H, Walkenfort B, Cansiz F, Bauer M, Olszewski D, Ramos-Nascimento A, Duhan V, Friedrich SK, Becker KA, Krawczyk A, Edwards MJ, Burchert A, Huber M, Friebus-Kardash J, Hardt C, Probst HC, Schumacher F, Kleuser B, Babiychuk EB, Sodeik B, Greber UF, Gulbins E, Lang KS, Fink J, G?thert JR, K?hrer K, Seibel J, Lang PA. Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease. Nat Commun. 2020 03 12; 11(1):1338. PMID: 32165633; PMCID: PMC7067866.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    52. Nimtz L, Hartmann J, Tigges J, Masjosthusmann S, Schmuck M, Theiss S, Adjaye J, Wigmann C, Wieczorek D, Hildebrandt B, Bendt F, Brockerhoff G, Ke?el E, K?hrer K, Petzsch P, H?benthal U, Fritsche E. Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation. Stem Cell Res. 2020 05; 45:101761. PMID: 32244191.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    53. Wang C, Hamacher A, Petzsch P, Schulz WA, Kassack MU, K?hrer K, Niegisch G, Hoffmann MJ. Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1. Cancers (Basel). 2020 Feb 03; 12(2). PMID: 32028599; PMCID: PMC7073167.
      Citations: 12     
    54. H?nsch S, Spona D, Murra G, K?hrer K, Subtil A, Furtado AR, Lichtenthaler SF, Dislich B, M?lleken K, Hegemann JH. Chlamydia-induced curvature of the host-cell plasma membrane is required for infection. Proc Natl Acad Sci U S A. 2020 02 04; 117(5):2634-2644. PMID: 31964834; PMCID: PMC7007526.
      Citations: 8     Fields:    Translation:HumansCells
    55. Hellwig B, Hengstler JG, Klindt C, Reich M, Stindt J, Rahnenf?hrer J, K?hrer K, Schoonjans K, H?ussinger D, Keitel V. The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver. Cells. 2019 11 19; 8(11). PMID: 31752395; PMCID: PMC6912679.
      Citations: 17     Fields:    Translation:AnimalsCells
    56. Skowron MA, Petzsch P, Hardt K, Wagner N, Beier M, Stepanow S, Drechsler M, Rieder H, K?hrer K, Niegisch G, Hoffmann MJ, Schulz WA. Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines. Sci Rep. 2019 10 09; 9(1):14476. PMID: 31597922; PMCID: PMC6785536.
      Citations: 4     Fields:    Translation:HumansCells
    57. Rex J, Tiedje C, Sawodny O, Gaestel M, Ehlting C, Albrecht U, Deenen R, K?hrer K, H?ussinger D, Bode JG. Cooperative and distinct functions of MK2 and MK3 in the regulation of the macrophage transcriptional response to lipopolysaccharide. Sci Rep. 2019 07 30; 9(1):11021. PMID: 31363109; PMCID: PMC6667695.
      Citations: 3     Fields:    Translation:AnimalsCells
    58. Hollmann MW, Hermanns H, Brandenburger T, Johannsen L, Prassek V, Kuebart A, Raile J, Wohlfromm S, K?hrer K, Huhn R. MiR-34a is differentially expressed in dorsal root ganglia in a rat model of chronic neuropathic pain. Neurosci Lett. 2019 08 24; 708:134365. PMID: 31278961.
      Citations: 9     Fields:    Translation:Animals
    59. Papazova I, Malchow B, Hasan A, Schmitt A, Falkai P, Trossbach SV, Hecher L, Schafflick D, Deenen R, Popa O, Lautwein T, Tschirner S, K?hrer K, Fehsel K, Winterer G, Meyer Zu H?rste G, Korth C. Dysregulation of a specific immune-related network of genes biologically defines a subset of schizophrenia. Transl Psychiatry. 2019 05 31; 9(1):156. PMID: 31150013; PMCID: PMC6544656.
      Citations: 15     Fields:    Translation:AnimalsCells
    60. Jaguva Vasudevan AA, Hoffmann MJ, Beck MLC, Poschmann G, Petzsch P, Wiek C, St?hler K, K?hrer K, Schulz WA, Niegisch G. HDAC5 Expression in Urothelial Carcinoma Cell Lines Inhibits Long-Term Proliferation but Can Promote Epithelial-to-Mesenchymal Transition. Int J Mol Sci. 2019 Apr 30; 20(9). PMID: 31052182; PMCID: PMC6539474.
      Citations: 14     Fields:    Translation:HumansCells
    61. Lang A, Yilmaz M, Hader C, Murday S, Kunz X, Wagner N, Wiek C, Petzsch P, K?hrer K, Koch J, Hoffmann MJ, Greife A, Schulz WA. Contingencies of UTX/KDM6A Action in Urothelial Carcinoma. Cancers (Basel). 2019 Apr 04; 11(4). PMID: 30987376; PMCID: PMC6520694.
      Citations: 14     
    62. Wiegering A, Petzsch P, K?hrer K, R?ther U, Gerhardt C. GLI3 repressor but not GLI3 activator is essential for mouse eye patterning and morphogenesis. Dev Biol. 2019 06 15; 450(2):141-154. PMID: 30953627.
      Citations: 5     Fields:    Translation:AnimalsCells
    63. Benga L, Fe?ler AT, Benten WPM, Engelhardt E, K?hrer K, Schwarz S, Sager M. Acinetobacter species in laboratory mice: species survey and antimicrobial resistance. Lab Anim. 2019 Oct; 53(5):470-477. PMID: 30567464.
      Citations: 1     Fields:    Translation:AnimalsCells
    64. Heinen A, Nederlof R, Panjwani P, Spychala A, Tschaidse T, Reffelt H, Boy J, Raupach A, G?decke S, Petzsch P, K?hrer K, Grandoch M, Petz A, Fischer JW, Alter C, Vasilevska J, Lang P, G?decke A. IGF1 Treatment Improves Cardiac Remodeling after Infarction by Targeting Myeloid Cells. Mol Ther. 2019 01 02; 27(1):46-58. PMID: 30528085; PMCID: PMC6319026.
      Citations: 15     Fields:    Translation:AnimalsCells
    65. Singh M, Bergmann L, Lang A, Pexa K, Kuck F, Stibane D, Janke L, Ezzahoini H, Lindecke A, Wiek C, Hanenberg H, K?hrer K, von Gall C, Reinke H, Piekorz RP. Gai3 signaling is associated with sexual dimorphic expression of the clock-controlled output gene Dbp in murine liver. Oncotarget. 2018 Jul 13; 9(54):30213-30224. PMID: 30100984; PMCID: PMC6084400.
      Citations: 1     Fields:    
    66. Ale-Agha N, Goy C, Jakobs P, Spyridopoulos I, Gonnissen S, Dyballa-Rukes N, Aufenvenne K, von Ameln F, Zurek M, Spannbrucker T, Eckermann O, Jakob S, Gorressen S, Abrams M, Grandoch M, Fischer JW, Unfried K, Altschmied J, Haendeler J, K?hrer K, Deenen R. CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine. PLoS Biol. 2018 06; 16(6):e2004408. PMID: 29927970; PMCID: PMC6013014.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    67. Wendel AF, Meyer S, Deenen R, K?hrer K, Kolbe-Busch S, Pfeffer K, Willmann M, Kaasch AJ, MacKenzie CR. Long-Term, Low-Frequency Cluster of a German-Imipenemase-1-Producing Enterobacter hormaechei ssp. steigerwaltii ST89 in a Tertiary Care Hospital in Germany. Microb Drug Resist. 2018 Nov; 24(9):1305-1315. PMID: 29750595.
      Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
    68. Masjosthusmann S, Becker D, Petzuch B, Siebert C, Barenys M, Baumann J, Dach K, Tigges J, Klose J, Deenen R, H?benthal U, K?hrer K, Fritsche E. A transcriptome comparison of time-matched developing human, mouse and rat neural progenitor cells reveals human uniqueness. Toxicol Appl Pharmacol. 2018 09 01; 354:40-55. PMID: 29753005.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    69. Suwala AK, Koch K, Rios DH, Aretz P, Uhlmann C, Ogorek I, Felsberg J, Reifenberger G, K?hrer K, Deenen R, Steiger HJ, Kahlert UD, Maciaczyk J. Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro. Oncotarget. 2018 Apr 27; 9(32):22703-22716. PMID: 29854309; PMCID: PMC5978259.
      Citations: 36     Fields:    
    70. Reis AC, Saeger W, Knappe UJ, Ballmann C, Thiel A, Korah HE, Stepanow S, K?hrer K, Reifenberger G, Knobbe-Thomsen CB, Scholl UI. USP8 Mutations in Pituitary Cushing Adenomas-Targeted Analysis by Next-Generation Sequencing. J Endocr Soc. 2018 Mar 01; 2(3):266-278. PMID: 29600293; PMCID: PMC5838826.
      Citations: 25     
    71. Endris V, Lassmann S, Weichert W, Pfarr N, Schirmacher P, Kovaleva V, Werner M, Bonzheim I, Fend F, Sperveslage J, Kaulich K, Zacher A, Reifenberger G, Stepanow S, Lerke S, Mayr T, Aust DE, Baretton G, Weidner S, Jung A, Kirchner T, Hansmann ML, Hirsch B, K?hrer K, Burbat L, von der Wall E, Dietel M, Hummel M. Multicenter validation of cancer gene panel-based next-generation sequencing for translational research and molecular diagnostics. Virchows Arch. 2018 Apr; 472(4):557-565. PMID: 29374318; PMCID: PMC5924673.
      Citations: 12     Fields:    Translation:Humans
    72. Wammers M, Schupp AK, Bode JG, Ehlting C, Wolf S, Graf D, Deenen R, K?hrer K, H?ussinger D. Reprogramming of pro-inflammatory human macrophages to an anti-inflammatory phenotype by bile acids. Sci Rep. 2018 01 10; 8(1):255. PMID: 29321478; PMCID: PMC5762890.
      Citations: 32     Fields:    Translation:HumansCells
    73. Eder T, Kobus S, Stallmann S, Stepanow S, K?hrer K, Hegemann JH, Rattei T. Genome sequencing of Chlamydia trachomatis serovars E and F reveals substantial genetic variation. Pathog Dis. 2017 12 29; 75(9). PMID: 29186396; PMCID: PMC5827700.
      Citations: 4     Fields:    Translation:HumansCells
    74. Henrich B, Kretzmer F, Deenen R, K?hrer K. Validation of a novel Mho microarray for a comprehensive characterisation of the Mycoplasma hominis action in HeLa cell infection. PLoS One. 2017; 12(7):e0181383. PMID: 28753664; PMCID: PMC5533444.
      Citations: 7     Fields:    Translation:HumansCells
    75. Seyfarth J, Ahlert H, Laws HJ, Karges B, Mayatepek E, Meissner T, Jacobsen M, F?rtsch K, Deenen R, K?hrer K. Dominant TNFa and impaired IL-2 cytokine profiles of CD4+ T cells from children with type-1 diabetes. Immunol Cell Biol. 2017 08; 95(7):630-639. PMID: 28377612.
      Citations: 3     Fields:    Translation:HumansCells
    76. Trujillo CM, Syson K, DeJesus MA, Hartman T, Jacobs WR, Bornemann S, Ioerger TR, Ehrt S, Korte J, Alber M, Koliwer-Brandl H, Deenen R, K?hrer K, Kalscheuer R. Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice. PLoS Pathog. 2016 Dec; 12(12):e1006043. PMID: 27936238; PMCID: PMC5148154.
      Citations: 16     Fields:    Translation:AnimalsCells
    77. Keitel V, Dr?ge C, Stepanow S, Fehm T, Mayatepek E, K?hrer K, H?ussinger D. Intrahepatic cholestasis of pregnancy (ICP): case report and review of the literature. Z Gastroenterol. 2016 Dec; 54(12):1327-1333. PMID: 27936482.
      Citations: 8     Fields:    Translation:HumansAnimals
    78. Sparwasser T, Limmer A, Mykicki N, Herrmann AM, Schwab N, Deenen R, Wachsmuth L, Klotz L, K?hrer K, Faber C, Wiendl H, Luger TA, Meuth SG, Loser K. Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease. Sci Transl Med. 2016 10 26; 8(362):362ra146. PMID: 27797962.
      Citations: 24     Fields:    Translation:AnimalsCells
    79. Wilk CM, Heinzler N, Boquoi A, Cadeddu RP, Strapatsas T, Dienst A, Majidi F, Bruns I, Schroeder T, Haas R, Kobbe G, Fenk R, Deenen R, K?hrer K. Lenalidomide consolidation treatment in patients with multiple myeloma suppresses myelopoieses but spares erythropoiesis. Int J Cancer. 2016 Nov 15; 139(10):2343-52. PMID: 27389073.
      Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
    80. Zahner S, Bloch W, Haas K, Weighardt H, Deenen R, K?hrer K, Clausen B, Boukamp P, Krutmann J, Esser C. Aryl Hydrocarbon Receptor in Keratinocytes Is Essential for Murine Skin?Barrier Integrity. J Invest Dermatol. 2016 11; 136(11):2260-2269. PMID: 27430407.
      Citations: 51     Fields:    Translation:AnimalsCells
    81. Santana-Varela S, Hermanns H, Wood JN, Zhao J, Neumann E, Brandenburger T, Deenen R, K?hrer K, Bauer I, Werdehausen R. MicroRNA-1-associated effects of neuron-specific brain-derived neurotrophic factor gene deletion in dorsal root ganglia. Mol Cell Neurosci. 2016 09; 75:36-43. PMID: 27346077; PMCID: PMC6675923.
      Citations: 8     Fields:    Translation:Animals
    82. Rammos C, Hendgen-Cotta UB, Totzeck M, Pohl J, French BA, Rassaf T, L?dike P, Fl?gel U, Deenen R, K?hrer K, G?decke A, Kelm M. Impact of dietary nitrate on age-related diastolic dysfunction. Eur J Heart Fail. 2016 06; 18(6):599-610. PMID: 27118445.
      Citations: 12     Fields:    Translation:AnimalsCells
    83. Zacher A, Kaulich K, Stepanow S, Wolter M, K?hrer K, Felsberg J, Malzkorn B, Reifenberger G. Molecular Diagnostics of Gliomas Using Next Generation Sequencing of a Glioma-Tailored Gene Panel. Brain Pathol. 2017 03; 27(2):146-159. PMID: 26919320; PMCID: PMC8029406.
      Citations: 77     Fields:    Translation:HumansCells
    84. Lang A, Grether-Beck S, Singh M, Kuck F, Jakob S, Kefalas A, Altinoluk-Hamb?chen S, Graffmann N, Schneider M, Lindecke A, Brenden H, Felsner I, Ezzahoini H, Marini A, Weinhold S, Vierk?tter A, Tigges J, Schmidt S, St?hler K, K?hrer K, Uhrberg M, Haendeler J, Krutmann J, Piekorz RP. MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. Aging (Albany NY). 2016 Mar; 8(3):484-505. PMID: 26959556; PMCID: PMC4833141.
      Citations: 59     Fields:    Translation:HumansCells
    85. Pinkerneil M, Arent T, Schulz WA, Hoffmann MJ, Deenen R, K?hrer K, Niegisch G. Inhibition of Class I Histone Deacetylases 1 and 2 Promotes Urothelial Carcinoma Cell Death by Various Mechanisms. Mol Cancer Ther. 2016 Feb; 15(2):299-312. PMID: 26772204.
      Citations: 33     Fields:    Translation:HumansCells
    86. Drusenheimer N, Migdal B, J?ckel S, Tveriakhina L, Scheider K, Schulz K, Gr?per J, K?hrer K, Klein T. The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015 Dec; 11(12):e1005749. PMID: 26720614; PMCID: PMC4697852.
      Citations: 14     Fields:    Translation:AnimalsCells
    87. Sorg UR, Behnke K, Degrandi D, Reich M, Keitel V, Herebian D, Beyer M, Schultze JL, Gabbert HE, Mayatepek E, Pfeffer K, Deenen R, K?hrer K, H?ussinger D. Cooperative role of lymphotoxin ? receptor and tumor necrosis factor receptor p55 in murine liver regeneration. J Hepatol. 2016 May; 64(5):1108-1117. PMID: 26708145.
      Citations: 7     Fields:    Translation:AnimalsCells
    88. Savani RC, Kiene LS, Homann S, Suvorava T, Rabausch B, M?ller J, Kojda G, Kretschmer I, Twarock S, Dai G, Deenen R, Hartwig S, Lehr S, K?hrer K, Grandoch M, Fischer JW. Deletion of Hyaluronan Synthase 3 Inhibits Neointimal Hyperplasia in Mice. Arterioscler Thromb Vasc Biol. 2016 Feb; 36(2):e9-16. PMID: 26586662; PMCID: PMC5222548.
      Citations: 18     Fields:    Translation:AnimalsCells
    89. Rammos C, Totzeck M, Deenen R, K?hrer K, Kelm M, Rassaf T, Hendgen-Cotta UB. Dietary nitrate is a modifier of vascular gene expression in old male mice. Oxid Med Cell Longev. 2015; 2015:658264. PMID: 25838870; PMCID: PMC4369962.
      Citations: 5     Fields:    Translation:AnimalsCells
    90. Grandoch M, Feldmann K, G?thert JR, Dick LS, Homann S, Klatt C, Bayer JK, Waldheim JN, Rabausch B, Nagy N, Oberhuber A, Deenen R, K?hrer K, Lehr S, Homey B, Pfeffer K, Fischer JW. Deficiency in lymphotoxin ? receptor protects from atherosclerosis in apoE-deficient mice. Circ Res. 2015 Apr 10; 116(8):e57-68. PMID: 25740843.
      Citations: 17     Fields:    Translation:AnimalsCells
    91. Deenen R, Kretschmer I, Zimmermann A, Seiler LF, Mayer P, Heim HK, Fischer JW, Freudenberger T, K?hrer K. Synthetic gestagens exert differential effects on arterial thrombosis and aortic gene expression in ovariectomized apolipoprotein E-deficient mice. Br J Pharmacol. 2014 Nov; 171(22):5032-48. PMID: 24923668; PMCID: PMC4253454.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    92. Pandyra AA, Sharma P, Diefenbach A, Gibbert K, Waibler Z, Lang KS, Xu HC, Grusdat M, Polz R, Huang J, Deenen R, K?hrer K, Rahbar R, L?hning M, H?cker L, H?ussinger D, Mak TW, Ohashi PS, Lang PA. Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity. Immunity. 2014 Jun 19; 40(6):949-60. PMID: 24909887.
      Citations: 127     Fields:    Translation:AnimalsCells
    93. Benga L, Benten WP, Engelhardt E, K?hrer K, Gougoula C, Sager M. 16S ribosomal DNA sequence-based identification of bacteria in laboratory rodents: a practical approach in laboratory animal bacteriology diagnostics. Lab Anim. 2014 Oct; 48(4):305-12. PMID: 24876090.
      Citations: 9     Fields:    Translation:AnimalsCells
    94. Ohse S, Boerries M, Busch H, Kalfalah F, Sobek S, Bornholz B, G?tz-R?sch C, Tigges J, Fritsche E, Krutmann J, K?hrer K, Deenen R, Boege F. Inadequate mito-biogenesis in primary dermal fibroblasts from old humans is associated with impairment of PGC1A-independent stimulation. Exp Gerontol. 2014 Aug; 56:59-68. PMID: 24699405.
      Citations: 24     Fields:    Translation:HumansCells
    95. Houben AP, Hennicke T, Liedtke S, Bosch J, Deenen R, K?hrer K, K?gler G. Comparing the gene expression profile of stromal cells from human cord blood and bone marrow: lack of the typical "bone" signature in cord blood cells. Stem Cells Int. 2013; 2013:631984. PMID: 24163699; PMCID: PMC3791663.
      Citations: 4     
    96. Mlynek A, Lukosz M, Graf M, Guettler C, Jakob S, Farrokh S, Kunze K, Goy C, Guardiola-Serrano F, Schaal H, Cortese-Krott M, Winkler C, Altschmied J, Haendeler J, B?chner N, Deenen R, K?hrer K. Two isoforms of Sister-Of-Mammalian Grainyhead have opposing functions in endothelial cells and in vivo. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1639-46. PMID: 23685552.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    97. Freytag EM, Bosch J, Houben AP, Radke TF, Liedtke S, Deenen R, K?hrer K, K?gler G. Neonatal mesenchymal-like cells adapt to surrounding cells. Stem Cell Res. 2013 Jul; 11(1):634-46. PMID: 23660338.
      Citations: 5     Fields:    Translation:HumansCells
    98. Degrandi D, Henrich B, Hopfe M, Deenen R, K?hrer K. Host cell responses to persistent mycoplasmas--different stages in infection of HeLa cells with Mycoplasma hominis. PLoS One. 2013; 8(1):e54219. PMID: 23326599; PMCID: PMC3543322.
      Citations: 33     Fields:    Translation:HumansCells
    99. Erkelenz S, Hillebrand F, Krikoni A, Widera D, Kaisers W, Gombert M, Dellen R, Pfeiffer T, Kaltschmidt B, Bosch V, Schaal H, Widera M, Deenen R, M?nk C, K?hrer K. An intronic G run within HIV-1 intron 2 is critical for splicing regulation of vif mRNA. J Virol. 2013 Mar; 87(5):2707-20. PMID: 23255806; PMCID: PMC3571361.
      Citations: 24     Fields:    Translation:HumansCells
    100. Kessels C, Peiseler L, Raupach A, Jacoby C, Vogt N, Lindecke A, Koch L, Heger J, Moellendorf S, Br?ning J, K?hrer K, G?decke A. IGF-IR signaling attenuates the age-related decline of diastolic cardiac function. Am J Physiol Endocrinol Metab. 2012 Jul 15; 303(2):E213-22. PMID: 22589390.
      Citations: 15     Fields:    Translation:AnimalsCells
    101. Linka RM, Risse SL, Bienemann K, Werner M, Linka Y, Krux F, Synaeve C, Deenen R, Ginzel S, Dvorsky R, Gombert M, Halenius A, Hartig R, Helminen M, Fischer A, Stepensky P, Vettenranta K, Ahmadian MR, Laws HJ, Fleckenstein B, Jumaa H, Latour S, Schraven B, Borkhardt A, K?hrer K. Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases. Leukemia. 2012 May; 26(5):963-71. PMID: 22289921.
      Citations: 54     Fields:    Translation:HumansCells
    102. Ebner A, Burghoff S, Ding Z, Romio M, Viethen C, Lindecke A, Fischer JW, Buchheiser A, K?hrer K, Schrader J. Inactivation of CD73 promotes atherogenesis in apolipoprotein E-deficient mice. Cardiovasc Res. 2011 Nov 01; 92(2):338-47. PMID: 21955554.
      Citations: 21     Fields:    Translation:AnimalsCells
    103. Lindecke A, Raupach A, Moellendorf S, Molojavyi A, K?hrer K, G?decke A. Myoglobin-deficient mice activate a distinct cardiac gene expression program in response to isoproterenol-induced hypertrophy. Physiol Genomics. 2010 Apr 01; 41(2):137-45. PMID: 20145201.
      Citations: 20     Fields:    Translation:Animals
    104. Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Heubner D, Hoerlein A, Michel G, Wedler H, Poustka A, Wiemann S, Schupp I, Bl?cker H, K?hrer K, Ottenw?lder B. The full-ORF clone resource of the German cDNA Consortium. BMC Genomics. 2007 Oct 31; 8:399. PMID: 17974005; PMCID: PMC2213676.
      Citations: 20     Fields:    Translation:Humans
    105. Gehrmann T, Richter L, Keitel V, Schliess F, Sch?fer C, K?hrer K, H?ussinger D. Modulation of gene expression profiles by hyperosmolarity and insulin. Cell Physiol Biochem. 2007; 20(5):369-86. PMID: 17762165.
      Citations: 5     Fields:    Translation:AnimalsCells
    106. Warskulat U, Andr?e B, L?sebrink J, K?hrer K, H?ussinger D. Switch from actin alpha1 to alpha2 expression and upregulation of biomarkers for pressure overload and cardiac hypertrophy in taurine-deficient mouse heart. Biol Chem. 2006 Oct-Nov; 387(10-11):1449-54. PMID: 17081118.
      Citations: 2     Fields:    Translation:AnimalsCells
    107. Thumm M, Vom Dahl S, Prick T, K?hrer K, H?ussinger D. In yeast, loss of Hog1 leads to osmosensitivity of autophagy. Biochem J. 2006 Feb 15; 394(Pt 1):153-61. PMID: 16321140; PMCID: PMC1386013.
      Citations: 19     Fields:    Translation:Animals
    108. Keitel V, Scheuring S, Kubitz R, K?hrer K, H?ussinger D. Benign recurrent intrahepatic cholestasis associated with mutations of the bile salt export pump. J Clin Gastroenterol. 2006 Feb; 40(2):171-5. PMID: 16394881.
      Citations: 15     Fields:    Translation:Humans
    109. Dransfeld O, Gehrmann T, Kircheis G, Holneicher C, Wettstein M, K?hrer K, H?ussinger D. Oligonucleotide microarray analysis of differential transporter regulation in the regenerating rat liver. Liver Int. 2005 Dec; 25(6):1243-58. PMID: 16343078.
      Citations: 18     Fields:    Translation:AnimalsCells
    110. Scheuring S, Mincheva A, Lichter P, Beyer A, M?ller S, K?hrer K. Comparative sequence and expression analyses of four mammalian VPS4 genes. Gene. 2003 Feb 13; 305(1):47-59. PMID: 12594041.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    111. Beeck A, Perdikouli M, Boos M, Mayer S, Scheuring S, Verhoef J, Fluit AC, Schmitz FJ, K?hrer K. Production of BRO beta-lactamases and resistance to complement in European Moraxella catarrhalis isolates. J Clin Microbiol. 2002 Apr; 40(4):1546-8. PMID: 11923393; PMCID: PMC140350.
      Citations: 10     Fields:    Translation:HumansCells
    112. Beyer A, Abts HF, Scheuring S, R?hricht RA, Sch?ning-Burkhardt B, M?ller S, K?hrer K. Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking. J Mol Biol. 2001 Sep 21; 312(3):469-80. PMID: 11563910.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    113. Schmitz FJ, Petridou J, Astfalk N, Scheuring S, Verhoef J, Fluit AC, Schwarz S, K?hrer K. Structural alterations in the translational attenuator of constitutively expressed erm(A) genes in Staphylococcus aureus. Antimicrob Agents Chemother. 2001 May; 45(5):1603-4. PMID: 11372641; PMCID: PMC90519.
      Citations: 3     Fields:    Translation:HumansCells
    114. Beyer A, Schulte KM, K?hrer K, Oberh?user S, R?her HD. Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: over-expression of the high-affinity receptor edg4 in differentiated thyroid cancer. Int J Cancer. 2001 Apr 15; 92(2):249-56. PMID: 11291053.
      Citations: 29     Fields:    Translation:HumansCells
    115. Mayer S, Fischer A, Scheuring S, Heisig P, Verhoef J, Fluit AC, Schmitz FJ, Boos M, K?hrer K. In vitro development of resistance to six quinolones in Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus. Antimicrob Agents Chemother. 2001 Mar; 45(3):938-42. PMID: 11181385; PMCID: PMC90398.
      Citations: 7     Fields:    Translation:HumansCells
    116. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bauersachs S, Blum H, Lauber J, Beyer A, Strack N, Mewes HW, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A, B?cher M, Bl?cker H, D?sterh?ft A, K?hrer K, Ottenw?lder B. Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Genome Res. 2001 Mar; 11(3):422-35. PMID: 11230166; PMCID: PMC311072.
      Citations: 69     Fields:    Translation:HumansCells
    117. Jones ME, Schmitz FJ, K?hrer K. Multiplex PCR for the Rapid Simultaneous Speciation and Detection of Methicillin-Resistance and Genes Encoding Toxin Production in Staphylococcus aureus. Methods Mol Med. 2001; 48:103-12. PMID: 21374410.
      Citations: 1     Fields:    
    118. Schmitz FJ, Fluit AC, Hafner D, Beeck A, Perdikouli M, Boos M, Scheuring S, Verhoef J, Von Eiff C, K?hrer K. Development of resistance to ciprofloxacin, rifampin, and mupirocin in methicillin-susceptible and -resistant Staphylococcus aureus isolates. Antimicrob Agents Chemother. 2000 Nov; 44(11):3229-31. PMID: 11036061; PMCID: PMC101641.
      Citations: 20     Fields:    Translation:HumansCells
    119. Schmitz FJ, Fluit AC, Lindenlauf E, Scheuring S, K?hrer K. Molecular analyses of possible mechanisms coding for low-level mupirocin resistance in clinical Staphylococcus aureus isolates. Eur J Clin Microbiol Infect Dis. 2000 Aug; 19(8):649-50. PMID: 11014635.
      Citations: 2     Fields:    Translation:HumansCells
    120. Sadurski R, Kray A, Boos M, Geisel R, Verhoef J, Fluit AC, Schmitz FJ, K?hrer K. Prevalence of macrolide-resistance genes in Staphylococcus aureus and Enterococcus faecium isolates from 24 European university hospitals. J Antimicrob Chemother. 2000 Jun; 45(6):891-4. PMID: 10837446.
      Citations: 50     Fields:    Translation:HumansCells
    121. Heinze M, Mengel M, Scheuring S, Schulte KM, K?hrer K, R?her HD. Complete sequencing and mRNA expression analysis of the MEN-I gene in adrenal myelolipoma. Horm Metab Res. 2000 May; 32(5):169-73. PMID: 10871156.
      Citations: 4     Fields:    Translation:Humans
    122. Jones ME, Boenink NM, Verhoef J, Schmitz FJ, K?hrer K. Multiple mutations conferring ciprofloxacin resistance in Staphylococcus aureus demonstrate long-term stability in an antibiotic-free environment. J Antimicrob Chemother. 2000 Mar; 45(3):353-6. PMID: 10702556.
      Citations: 15     Fields:    Translation:Cells
    123. Simon D, Dotzenrath C, Scheuring S, Schulte KM, K?hrer K, R?her HD. Sequence analysis of the MEN I gene in two patients with multiple cutaneous lipomas and endocrine tumors. Horm Metab Res. 2000 Feb; 32(2):76-9. PMID: 10741690.
      Citations: 1     Fields:    Translation:Humans
    124. Jones ME, Sahm DF, Martin N, Scheuring S, Heisig P, Thornsberry C, Schmitz FJ, K?hrer K. Prevalence of gyrA, gyrB, parC, and parE mutations in clinical isolates of Streptococcus pneumoniae with decreased susceptibilities to different fluoroquinolones and originating from Worldwide Surveillance Studies during the 1997-1998 respiratory season. Antimicrob Agents Chemother. 2000 Feb; 44(2):462-6. PMID: 10639387; PMCID: PMC89708.
      Citations: 57     Fields:    Translation:HumansCells
    125. Mengel M, Heinze M, Simon D, Scheuring S, Schulte KM, K?hrer K, R?her HD. Complete sequencing and messenger ribonucleic acid expression analysis of the MEN I gene in adrenal cancer. J Clin Endocrinol Metab. 2000 Jan; 85(1):441-8. PMID: 10634422.
      Citations: 9     Fields:    Translation:HumansCells
    126. Fluit AC, Brisse S, Verhoef J, Milatovic D, Schmitz FJ, K?hrer K. Molecular epidemiology of quinolone resistance and comparative in vitro activities of new quinolones against European Staphylococcus aureus isolates. FEMS Immunol Med Microbiol. 1999 Dec; 26(3-4):281-7. PMID: 10575140.
      Citations: 23     Fields:    Translation:HumansCells
    127. Heinze M, Mengel M, Simon D, Scheuring S, Schulte KM, K?hrer K, R?her HD. MEN I gene mutations in sporadic adrenal adenomas. Hum Genet. 1999 Dec; 105(6):603-10. PMID: 10647896.
      Citations: 4     Fields:    Translation:Humans
    128. Welss T, Mirmohammadsadegh A, Michel G, Ruzicka T, Abts HF, K?hrer K. Cloning and characterization of hurpin (protease inhibitor 13): A new skin-specific, UV-repressible serine proteinase inhibitor of the ovalbumin serpin family. J Mol Biol. 1999 Oct 15; 293(1):29-39. PMID: 10512713.
      Citations: 7     Fields:    Translation:HumansCells
    129. Brisse S, Fluit AC, Wagner U, Heisig P, Milatovic D, Verhoef J, Scheuring S, Schmitz FJ, K?hrer K. Association of alterations in ParC and GyrA proteins with resistance of clinical isolates of Enterococcus faecium to nine different fluoroquinolones. Antimicrob Agents Chemother. 1999 Oct; 43(10):2513-6. PMID: 10508034; PMCID: PMC89510.
      Citations: 7     Fields:    Translation:HumansCells
    130. Brisse S, Milatovic D, Fluit AC, Verhoef J, Martin N, Scheuring S, Schmitz FJ, K?hrer K. Comparative in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Enterobacter aerogenes clinical isolates with alterations in GyrA and ParC proteins. Antimicrob Agents Chemother. 1999 Aug; 43(8):2051-5. PMID: 10428935; PMCID: PMC89413.
      Citations: 12     Fields:    Translation:HumansCells
    131. Scheuring S, Bodor O, Beyer A, R?hricht RA, M?ller S, K?hrer K. Cloning, characterisation, and functional expression of the Mus musculus SKD1 gene in yeast demonstrates that the mouse SKD1 and the yeast VPS4 genes are orthologues and involved in intracellular protein trafficking. Gene. 1999 Jun 24; 234(1):149-59. PMID: 10393249.
      Citations: 7     Fields:    Translation:AnimalsCells
    132. Scheuring S, Verhoef J, Fluit A, Heinz HP, Jones ME, Schmitz FJ, K?hrer K. The stability of grlA, grlB, gyrA, gyrB and norA mutations and MIC values of five fluoroquinolones in three different clonal populations of methicillin-resistant Staphylococcus aureus. Clin Microbiol Infect. 1999 May; 5(5):287-290. PMID: 11856269.
      Citations: 10     Fields:    
    133. Lang HR, Ecker M, K?hrer K. Experience with cardiac troponin T in difficult cases. Eur Heart J. 1998 Nov; 19 Suppl N:N38-41. PMID: 9857938.
      Citations: 1     Fields:    Translation:Humans
    134. Schmitz FJ, Hertel B, Hofmann B, Scheuring S, Verhoef J, Fluit AC, Heinz HP, Jones ME, K?hrer K. Relationship between mutations in the coding and promoter regions of the norA genes in 42 unrelated clinical isolates of Staphylococcus aureus and the MICs of norfloxacin for these strains. J Antimicrob Chemother. 1998 Oct; 42(4):561-3. PMID: 9818767.
      Citations: 8     Fields:    Translation:HumansCells
    135. Staudt S, Niederacher D, Finken-Eigen M, Goretzki PE, Schulte KM, K?hrer K, R?her HD. Rare loss of heterozygosity of the MTS1 and MTS2 tumor suppressor genes in differentiated human thyroid cancer. Horm Metab Res. 1998 Sep; 30(9):549-54. PMID: 9808321.
      Citations: 2     Fields:    Translation:HumansCells
    136. Homey B, Abts HF, Ruzicka T, Michel G, Mirmohammadsadegh A, K?hrer K. Differential modulation of pro- and anti-inflammatory cytokine receptors by N-(4-trifluoromethylphenyl)-2-cyano-3-hydroxy-crotonic acid amide (A77 1726), the physiologically active metabolite of the novel immunomodulator leflunomide. Biochem Pharmacol. 1998 May 01; 55(9):1523-9. PMID: 10076546.
      Citations: 1     Fields:    Translation:HumansCells
    137. Jones ME, Hofmann B, Hansen B, Scheuring S, Fluit A, Verhoef J, Hadding U, Heinz HP, Schmitz FJ, L?ckefahr M, K?hrer K. Characterization of grlA, grlB, gyrA, and gyrB mutations in 116 unrelated isolates of Staphylococcus aureus and effects of mutations on ciprofloxacin MIC. Antimicrob Agents Chemother. 1998 May; 42(5):1249-52. PMID: 9593159; PMCID: PMC105791.
      Citations: 56     Fields:    Translation:HumansCells
    138. Hofmann B, Hansen B, Scheuring S, Klootwijk M, Verhoef J, Fluit A, Heinz HP, Jones ME, Schmitz FJ, L?ckefahr M, K?hrer K. Relationship between ciprofloxacin, ofloxacin, levofloxacin, sparfloxacin and moxifloxacin (BAY 12-8039) MICs and mutations in grlA, grlB, gyrA and gyrB in 116 unrelated clinical isolates of Staphylococcus aureus. J Antimicrob Chemother. 1998 Apr; 41(4):481-4. PMID: 9598779.
      Citations: 32     Fields:    Translation:HumansCells
    139. Steiert M, Hofmann B, Verhoef J, Hadding U, Heinz HP, Schmitz FJ, K?hrer K. Development of a multiplex-PCR for direct detection of the genes for enterotoxin B and C, and toxic shock syndrome toxin-1 in Staphylococcus aureus isolates. J Med Microbiol. 1998 Apr; 47(4):335-40. PMID: 9569000.
      Citations: 12     Fields:    Translation:HumansCells
    140. Steiert M, Tichy HV, Hofmann B, Verhoef J, Heinz HP, Jones ME, Schmitz FJ, K?hrer K. Typing of methicillin-resistant Staphylococcus aureus isolates from D?sseldorf by six genotypic methods. J Med Microbiol. 1998 Apr; 47(4):341-51. PMID: 9569001.
      Citations: 21     Fields:    Translation:HumansCells
    141. Finken-Eigen M, Michel A, Grevelding CG, Kunz W, Sch?ssler P, K?hrer K. A female-specific cDNA sequence of Schistosoma mansoni encoding an amidase that is expressed in the gastrodermis. Parasitology. 1998 Feb; 116 ( Pt 2):131-7. PMID: 9509022.
      Citations:    Fields:    Translation:AnimalsCells
    142. Antoch G, Ellrichmann M, Finken-Eigen M, Simon D, Goretzki PE, Schulte KM, K?hrer K, R?her HD. Regulation of the HGF-receptor c-met in the thyroid gland. Exp Clin Endocrinol Diabetes. 1998; 106(4):310-8. PMID: 9792464.
      Citations: 2     Fields:    Translation:HumansCells
    143. Finken-Eigen M, M?ller S, K?hrer K. Cloning and characterization of a dominant-negative vps1 allele of the yeast Saccharomyces cerevisiae. Biol Chem. 1997 Oct; 378(10):1187-91. PMID: 9372190.
      Citations:    Fields:    Translation:HumansAnimalsCells
    144. Mackenzie CR, Hofmann B, Verhoef J, Finken-Eigen M, Heinz HP, Schmitz FJ, K?hrer K. Specific information concerning taxonomy, pathogenicity and methicillin resistance of staphylococci obtained by a multiplex PCR. J Med Microbiol. 1997 Sep; 46(9):773-8. PMID: 9291889.
      Citations: 16     Fields:    Translation:HumansCells
    145. Breuhahn K, Michel G, Esser P, Ruzicka T, Abts HF, K?hrer K. Analysis of UVB-modulated gene expression in human keratinocytes by mRNA differential display polymerase chain reaction. Photochem Photobiol. 1997 Sep; 66(3):363-7. PMID: 9297979.
      Citations: 1     Fields:    Translation:HumansCells
    146. Finken-Eigen M, R?hricht RA, K?hrer K. The VPS4 gene is involved in protein transport out of a yeast pre-vacuolar endosome-like compartment. Curr Genet. 1997 Jun; 31(6):469-80. PMID: 9211789.
      Citations: 20     Fields:    Translation:Cells
    147. Domdey H, Fingen-Eigen M, K?hrer K. The ribosomal protein gene RPS3 is an essential single copy gene of the yeast Saccharomyces cerevisiae. Biochem Biophys Res Commun. 1996 Jun 14; 223(2):397-403. PMID: 8670293.
      Citations: 6     Fields:    Translation:AnimalsCells
    148. Rieder SE, Banta LM, McCaffery JM, Emr SD, K?hrer K. Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. Mol Biol Cell. 1996 Jun; 7(6):985-99. PMID: 8817003; PMCID: PMC275948.
      Citations: 144     Fields:    Translation:AnimalsCells
    149. Emr SD, K?hrer K. The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases. J Biol Chem. 1993 Jan 05; 268(1):559-69. PMID: 8416961.
      Citations: 16     Fields:    Translation:AnimalsCells
    150. Domdey H, K?hrer K. Preparation of high molecular weight RNA. Methods Enzymol. 1991; 194:398-405. PMID: 1706459.
      Citations: 251     Fields:    Translation:AnimalsCells
    151. Vogel K, Domdey H, K?hrer K. A yeast tRNA precursor containing a pre-mRNA intron is spliced via the pre-mRNA splicing mechanism. EMBO J. 1990 Mar; 9(3):705-9. PMID: 2178925; PMCID: PMC551724.
      Citations: 5     Fields:    Translation:AnimalsCells
    152. Kutchan TM, Domdey H, K?hrer K. Specific oligodeoxynucleotide probes obtained through RNA sequencing. DNA. 1989 Mar; 8(2):143-7. PMID: 2924686.
      Citations: 3     Fields:    Translation:AnimalsCells
    153. Domdey H, K?hrer K. Splicing and spliceosome formation of the yeast MATa1 transcript require a minimum distance from the 5' splice site to the internal branch acceptor site. Nucleic Acids Res. 1988 Oct 25; 16(20):9457-75. PMID: 3054807; PMCID: PMC338756.
      Citations: 8     Fields:    Translation:AnimalsCells
    154. Grummt I, Horak I, K?hrer K. Functional RNA polymerase II promoters in solitary retroviral long terminal repeats (LTR-IS elements). Nucleic Acids Res. 1985 Apr 11; 13(7):2631-45. PMID: 2987860; PMCID: PMC341180.
      Citations: 5     Fields:    Translation:AnimalsCells

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