Next Generation Sequencing Competence Network

Next Generation Sequencing Competence Network

e.g. CCGA
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Joachim L. Schultze

Prof. Dr.
University of Bonn
Genomics & Immunoregulation
Carl-Troll Straße 31, 53115 Bonn, Germany
Bonn 53115
+49 228 7362787
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Steiner S, Fehrer A, Hoheisel F, Schoening S, Aschenbrenner A, Babel N, Bellmann-Strobl J, Finke C, Fluge ?, Froehlich L, Goebel A, Grande B, Haas JP, Hohberger B, Jason LA, Komaroff AL, Lacerda E, Liebl M, Maier A, Mella O, Nacul L, Paul F, Prusty BK, Puta C, Riemekasten G, Ries W, Rowe PC, Sawitzki B, Shoenfeld Y, Schultze JL, Seifert M, Sep?lveda N, Sotzny F, Stein E, Stingl M, Ufer F, Veauthier C, Westermeier F, Wirth K, Wolfarth B, Zalewski P, Behrends U, Scheibenbogen C. Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome - State of the art: Report of the 2nd international meeting at the Charit? Fatigue Center. Autoimmun Rev. 2023 Sep 22; 22(11):103452. PMID: 37742748.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    2. Suen TK, Moorlag SJCFM, Li W, de Bree CLJ, Koeken VACM, Mourits VP, Dijkstra H, Lemmers H, Bhat J, Xu CJ, Joosten LAB, Schultze JL, Li Y, Placek K, Netea MG. BCG vaccination induces innate immune memory in gamma delta T cells in humans. J Leukoc Biol. 2023 Sep 06. PMID: 37672677.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    3. Temba GS, Vadaq N, Kullaya V, Pecht T, Lionetti P, Cavalieri D, Schultze JL, Kavishe R, Joosten LAB, van der Ven AJ, Mmbaga BT, Netea MG, de Mast Q. Differences in the inflammatory proteome of East African and Western European adults and associations with environmental and dietary factors. Elife. 2023 08 09; 12. PMID: 37555575; PMCID: PMC10473835.
      Citations:    Fields:    Translation:Humans
    4. Kooistra EJ, Dahm K, van Herwaarden AE, Gerretsen J, Nuesch Germano M, Mauer K, Smeets RL, van der Velde S, van den Berg MJW, van der Hoeven JG, Aschenbrenner AC, Schultze JL, Ulas T, Kox M, Pickkers P. Molecular mechanisms and treatment responses of pulmonary fibrosis in severe COVID-19. Respir Res. 2023 Aug 09; 24(1):196. PMID: 37559053; PMCID: PMC10413531.
      Citations: 2     Fields:    Translation:HumansCells
    5. Scheibenbogen C, Bellmann-Strobl JT, Heindrich C, Wittke K, Stein E, Franke C, Pr?ss H, Pre?ler H, Machule ML, Audebert H, Finke C, Zimmermann HG, Sawitzki B, Meisel C, Toelle M, Krueger A, Aschenbrenner AC, Schultze JL, Beyer MD, Ralser M, M?lleder M, Sander LE, Konietschke F, Paul F, Stojanov S, Bruckert L, Hedderich DM, Knolle F, Riemekasten G, Vehreschild MJGT, Cornely OA, Behrends U, Burock S. Fighting Post-COVID and ME/CFS - development of curative therapies. Front Med (Lausanne). 2023; 10:1194754. PMID: 37396922; PMCID: PMC10309204.
      Citations: 9     
    6. Sikkema L, Ram?rez-Su?stegui C, Strobl DC, Gillett TE, Zappia L, Madissoon E, Markov NS, Zaragosi LE, Ji Y, Ansari M, Arguel MJ, Apperloo L, Banchero M, B?cavin C, Berg M, Chichelnitskiy E, Chung MI, Collin A, Gay ACA, Gote-Schniering J, Hooshiar Kashani B, Inecik K, Jain M, Kapellos TS, Kole TM, Leroy S, Mayr CH, Oliver AJ, von Papen M, Peter L, Taylor CJ, Walzthoeni T, Xu C, Bui LT, De Donno C, Dony L, Faiz A, Guo M, Gutierrez AJ, Heumos L, Huang N, Ibarra IL, Jackson ND, Kadur Lakshminarasimha Murthy P, Lotfollahi M, Tabib T, Talavera-L?pez C, Travaglini KJ, Wilbrey-Clark A, Worlock KB, Yoshida M, Lung Biological Network Consortium, van den Berge M, Boss? Y, Desai TJ, Eickelberg O, Kaminski N, Krasnow MA, Lafyatis R, Nikolic MZ, Powell JE, Rajagopal J, Rojas M, Rozenblatt-Rosen O, Seibold MA, Sheppard D, Shepherd DP, Sin DD, Timens W, Tsankov AM, Whitsett J, Xu Y, Banovich NE, Barbry P, Duong TE, Falk CS, Meyer KB, Kropski JA, Pe'er D, Schiller HB, Tata PR, Schultze JL, Teichmann SA, Misharin AV, Nawijn MC, Luecken MD, Theis FJ. An integrated cell atlas of the lung in health and disease. Nat Med. 2023 Jun; 29(6):1563-1577. PMID: 37291214; PMCID: PMC10287567.
      Citations: 48     Fields:    Translation:HumansCells
    7. Kapellos TS, Ba?ler K, Fujii W, Nalkurthi C, Schaar AC, Bonaguro L, Pecht T, Galvao I, Agrawal S, Saglam A, Dudkin E, Frishberg A, de Domenico E, Horne A, Donovan C, Kim RY, Gallego-Ortega D, Gillett TE, Ansari M, Schulte-Schrepping J, Offermann N, Antignano I, Sivri B, Lu W, Eapen MS, van Uelft M, Osei-Sarpong C, van den Berge M, Donker HC, Groen HJM, Sohal SS, Klein J, Schreiber T, Fei?t A, Yildirim A?, Schiller HB, Nawijn MC, Becker M, H?ndler K, Beyer M, Capasso M, Ulas T, Hasenauer J, Pizarro C, Theis FJ, Hansbro PM, Skowasch D, Schultze JL. Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease. Cell Rep. 2023 Jun 27; 42(6):112525. PMID: 37243592; PMCID: PMC10320832.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    8. M?ller S, Schultze JL. Systems analysis of human innate immunity in COVID-19. Semin Immunol. 2023 Jul; 68:101778. PMID: 37267758; PMCID: PMC10201327.
      Citations:    Fields:    Translation:HumansCells
    9. Gressier E, Schulte-Schrepping J, Petrov L, Brumhard S, Stubbemann P, Hiller A, Obermayer B, Spitzer J, Kostevc T, Whitney PG, Bachem A, Odainic A, van de Sandt C, Nguyen THO, Ashhurst T, Wilson K, Oates CVL, Gearing LJ, Meischel T, Hochheiser K, Greyer M, Clarke M, Kreutzenbeck M, Gabriel SS, Kastenm?ller W, Kurts C, Londrigan SL, Kallies A, Kedzierska K, Hertzog PJ, Latz E, Chen YE, Radford KJ, Chopin M, Schroeder J, Kurth F, Gebhardt T, Sander LE, Sawitzki B, Schultze JL, Schmidt SV, Bedoui S. CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity. Nat Immunol. 2023 06; 24(6):979-990. PMID: 37188942.
      Citations: 4     Fields:    Translation:HumansCells
    10. Wong YY, Harbison JE, Hope CM, Gundsambuu B, Brown KA, Wong SW, Brown CY, Couper JJ, Breen J, Liu N, Pederson SM, K?hne M, Klee K, Schultze J, Beyer M, Sadlon T, Barry SC. Parallel recovery of chromatin accessibility and gene expression dynamics from frozen human regulatory T cells. Sci Rep. 2023 04 04; 13(1):5506. PMID: 37016052; PMCID: PMC10073253.
      Citations: 2     Fields:    Translation:HumansCells
    11. Verstegen NJM, Pollastro S, Unger PA, Marsman C, Elias G, Jorritsma T, Streutker M, Bassler K, Haendler K, Rispens T, Schultze JL, Ten Brinke A, Beyer M, van Ham SM. Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates. Elife. 2023 03 02; 12. PMID: 36861964; PMCID: PMC10005767.
      Citations: 4     Fields:    Translation:HumansCells
    12. Katzmarski N, Dom?nguez-Andr?s J, Cirovic B, Renieris G, Ciarlo E, Le Roy D, Lepikhov K, Kattler K, Gasparoni G, H?ndler K, Theis H, Beyer M, van der Meer JWM, Joosten LAB, Walter J, Schultze JL, Roger T, Giamarellos-Bourboulis EJ, Schlitzer A, Netea MG. Author Correction: Transmission of trained immunity and heterologous resistance to infections across generations. Nat Immunol. 2023 Feb; 24(2):371-372. PMID: 36653441.
      Citations:    Fields:    
    13. Schultze JL. Building Trust in Medical Use of Artificial Intelligence - The Swarm Learning Principle. J CME. 2023; 12(1):2162202. PMID: 36969482; PMCID: PMC10031775.
      Citations:    
    14. Vos WAJW, Groenendijk AL, Blaauw MJT, van Eekeren LE, Navas A, Cleophas MCP, Vadaq N, Matzaraki V, Dos Santos JC, Meeder EMG, Fr?berg J, Weijers G, Zhang Y, Fu J, Ter Horst R, Bock C, Knoll R, Aschenbrenner AC, Schultze J, Vanderkerckhove L, Hwandih T, Wonderlich ER, Vemula SV, van der Kolk M, de Vet SCP, Blok WL, Brinkman K, Rokx C, Schellekens AFA, de Mast Q, Joosten LAB, Berrevoets MAH, Stalenhoef JE, Verbon A, van Lunzen J, Netea MG, van der Ven AJAM. The 2000HIV study: Design, multi-omics methods and participant characteristics. Front Immunol. 2022; 13:982746. PMID: 36605197; PMCID: PMC9809279.
      Citations: 2     Fields:    
    15. Royero P, Quatraccioni A, Fr?ngel R, Silva MH, Bast A, Ulas T, Beyer M, Opitz T, Schultze JL, Graham ME, Oberlaender M, Becker A, Schoch S, Beck H. Circuit-selective cell-autonomous regulation of inhibition in pyramidal neurons by Ste20-like kinase. Cell Rep. 2022 Dec 06; 41(10):111757. PMID: 36476865.
      Citations:    Fields:    
    16. Wischhof L, Lee HM, Tutas J, Overkott C, Tedt E, Stork M, Peitz M, Br?stle O, Ulas T, H?ndler K, Schultze JL, Ehninger D, Nicotera P, Salomoni P, Bano D. BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation. EMBO J. 2022 Dec 01; 41(23):e110595. PMID: 36305367.
      Citations: 2     Fields:    Translation:AnimalsCells
    17. Bonaguro L, Schulte-Schrepping J, Carraro C, Sun LL, Reiz B, Gem?nd I, Saglam A, Rahmouni S, Georges M, Arts P, Hoischen A, Joosten LAB, van de Veerdonk FL, Netea MG, H?ndler K, Mukherjee S, Ulas T, Schultze JL, Aschenbrenner AC. Human variation in population-wide gene expression data predicts gene perturbation phenotype. iScience. 2022 Nov 18; 25(11):105328. PMID: 36310583; PMCID: PMC9614568.
      Citations: 1     
    18. Mishra N, Aden K, Blase JI, Baran N, Bordoni D, Tran F, Conrad C, Avalos D, Jaeckel C, Scherer M, S?rensen SB, Overgaard SH, Schulte B, Nikolaus S, Rey G, Gasparoni G, Lyons PA, Schultze JL, Walter J, Andersen V, SYSCID Consortium, Dermitzakis ET, Schreiber S, Rosenstiel P. Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease. Genome Med. 2022 09 24; 14(1):110. PMID: 36153599; PMCID: PMC9509553.
      Citations: 12     Fields:    Translation:Humans
    19. Bonaguro L, Schulte-Schrepping J, Ulas T, Aschenbrenner AC, Beyer M, Schultze JL. A guide to systems-level immunomics. Nat Immunol. 2022 10; 23(10):1412-1423. PMID: 36138185.
      Citations: 11     Fields:    
    20. Carraro C, Bonaguro L, Schulte-Schrepping J, Horne A, Oestreich M, Warnat-Herresthal S, Helbing T, De Franco M, Haendler K, Mukherjee S, Ulas T, Gandin V, Goettlich R, Aschenbrenner AC, Schultze JL, Gatto B. Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state. Elife. 2022 08 31; 11. PMID: 36043458; PMCID: PMC9433094.
      Citations: 1     Fields:    Translation:Cells
    21. Powell P, Sarkans U, Denning J, Papatheodorou I, von Papen M, Madissoon E, Firsova AB, Berg M, Gay ACA, Larsson L, Sountoulidis A, Teichmann SA, van Eunen K, Koppelman GH, Saeb-Parsy K, Timens W, Lundeberg J, van den Berge M, Nilsson M, Petoukhov I, Misharin AV, Adcock IM, Samakovlis C, Meyer KB, Nawijn MC, Luecken MD, Zaragosi LE, Sikkema L, De Domenico E, K?mmerle L, Saglam A, Schniering J, Mayr CH, Abalo XM, Leroy S, Horv?th P, Schultze JL, Schiller HB, Barbry P, Theis FJ. The discovAIR project: a roadmap towards the Human Lung Cell Atlas. Eur Respir J. 2022 08; 60(2). PMID: 35086829; PMCID: PMC9386332.
      Citations: 8     Fields:    Translation:Humans
    22. Cottone L, Ligammari L, Lee HM, Knowles HJ, Henderson S, Bianco S, Davies C, Strauss S, Amary F, Leite AP, Tirabosco R, Haendler K, Schultze JL, Herrero J, O'Donnell P, Grigoriadis AE, Salomoni P, Flanagan AM. Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone. Cell Death Differ. 2022 Aug 03. PMID: 36138226.
      Citations: 7     Fields:    
    23. Ba?ler K, Fujii W, Kapellos TS, Dudkin E, Reusch N, Horne A, Reiz B, Luecken MD, Osei-Sarpong C, Warnat-Herresthal S, Bonaguro L, Schulte-Schrepping J, Wagner A, G?nther P, Pizarro C, Schreiber T, Knoll R, Holsten L, Kr?ger C, De Domenico E, Becker M, H?ndler K, Wohnhaas CT, Baumgartner F, K?hler M, Theis H, Kraut M, Wadsworth MH, Hughes TK, Ferreira HJ, Hinkley E, Kaltheuner IH, Geyer M, Thiele C, Shalek AK, Fei?t A, Thomas D, Dickten H, Beyer M, Baum P, Yosef N, Aschenbrenner AC, Ulas T, Hasenauer J, Theis FJ, Skowasch D, Schultze JL. Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation. Front Immunol. 2022; 13:917232. PMID: 35979364; PMCID: PMC9377018.
      Citations: 3     Fields:    Translation:HumansCells
    24. Schultze JL, B?ttner M, Becker M. Swarm immunology: harnessing blockchain technology and artificial intelligence in human immunology. Nat Rev Immunol. 2022 07; 22(7):401-403. PMID: 35624333; PMCID: PMC9136788.
      Citations: 1     Fields:    Translation:Humans
    25. Kooistra E, Nuesch-Germano M, Pecht T, Milman N, Reusch N, Bruse N, van Rijssen E, van Cranenbroek B, Koenen HJ, Heesakkers H, van den Boogaard M, Zegers M, Pickkers P, Theis FJ, Shen-Orr SS, Kox M, Frishberg A, Warnat-Herresthal S, H?ndler K, Theis H, Kraut M, Becker M, Aschenbrenner AC, Ulas T, Schultze JL. Mature neutrophils and a NF-?B-to-IFN transition determine the unifying disease recovery dynamics in COVID-19. Cell Rep Med. 2022 06 21; 3(6):100652. PMID: 35675822; PMCID: PMC9110324.
      Citations: 7     Fields:    Translation:HumansCells
    26. Li Q, Wang Y, Sun Q, Lin L, Jiang J, Shao C, Li P, He X, Hua F, Niu Z, Ma C, Zhu Y, Ippolito G, Piacentini M, Melino S, Weiss FD, Andreano E, Latz E, Rappuoli R, Mantovani A, Mak TW, Shi Y, Knopf J, Herrmann M, Estaquier J, Schultze JL, Melino G. Immune response in COVID-19: what is next? Cell Death Differ. 2022 06; 29(6):1107-1122. PMID: 35581387; PMCID: PMC9110941.
      Citations: 42     Fields:    Translation:HumansCellsPHPublic Health
    27. Jackson J, Wischhof L, Scifo E, Pellizzer A, Wang Y, Piazzesi A, Gentile D, Siddig S, Stork M, Hopkins CE, Weis J, Schultze JL, Nicotera P, Ehninger D, Bano D, H?ndler K, Roos A. SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells. Mol Metab. 2022 07; 61:101503. PMID: 35452878; PMCID: PMC9170783.
      Citations: 2     Fields:    Translation:AnimalsCells
    28. Duy PQ, Weise SC, Li XJ, Liang D, Dahl PJ, Ma S, Spajic A, Dong W, Juusola J, Kiziltug E, Kundishora AJ, Koundal S, Pedram MZ, Juranek SA, Cuevas E, Hao LT, Jux B, Liu F, Kim SK, Li M, Yang Y, Takeo Y, Duque A, Nelson-Williams C, Ha Y, Selvaganesan K, Robert SM, Singh AK, Allington G, Furey CG, Timberlake AT, Reeves BC, Smith H, Dunbar A, DeSpenza T, Goto J, Marlier A, Moreno-De-Luca A, Yu X, Butler WE, Carter BS, Lake EMR, Constable RT, Rakic P, Lin H, Deniz E, Benveniste H, Malvankar NS, Estrada-Veras JI, Walsh CA, Alper SL, Paeschke K, Doetzlhofer A, Jin SC, Lifton RP, Sestan N, Kolanus W, Kahle KT, Marini C, Torres-Fern?ndez LA, H?ndler K, De Domenico E, Becker M, Ulas T, Sousa AMM, Schultze JL, Wulczyn FG. Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus. Nat Neurosci. 2022 04; 25(4):458-473. PMID: 35379995; PMCID: PMC9664907.
      Citations: 25     Fields:    Translation:HumansAnimals
    29. Gabriel M, Schultze JL, Nicotera P. Time for a voluntary crisis research service. Cell Death Differ. 2022 Apr; 29(4):888-890. PMID: 35314771; PMCID: PMC8935265.
      Citations:    Fields:    
    30. Piazzesi A, Wang Y, Jackson J, Wischhof L, Zeisler-Diehl V, Scifo E, Oganezova I, Hoffmann T, Bertan F, Wrobel CJJ, Schroeder FC, Ehninger D, Schultze JL, Schreiber L, van Echten-Deckert G, Nicotera P, Bano D, G?mez Mart?n P, H?ndler K. CEST-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants. EMBO Rep. 2022 05 04; 23(5):e52606. PMID: 35297148; PMCID: PMC9066074.
      Citations: 4     Fields:    Translation:AnimalsCells
    31. Conlon TM, Jeridi A, Kim R, Lang NJ, Ansari M, Novikova M, Jiang D, Strunz M, Gaianova M, Hollauer C, Gabriel C, Angelidis I, Doll S, Pestoni JC, Edelmann SL, Bassler K, Van Eeckhoutte HP, Rodius S, Genes Robles CM, Smirnova N, Rehberg M, Agarwal C, Krikki I, Piavaux B, Verleden SE, Vanaudenaerde B, Dittmar G, Bracke KR, Schultze JL, Watz H, Eickelberg O, Stoeger T, Burgstaller G, Heissmeyer V, Rinkevich Y, Schiller HB, Conrad M, Schneider R, G?nes G?nsel G, Ert?z Z, Kohlhepp MS, Guillot A, Kayalar ?, Konyalilar N, Kanashova T, Ballester-L?pez C, K?nigshoff M, Tacke F, Bayram H, Yildirim A?. The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD. Nat Commun. 2022 03 14; 13(1):1303. PMID: 35288557; PMCID: PMC8921220.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    32. Ochs HD, Overmyer KA, Coon JJ, Balnis J, Jaitovich A, Schulte-Schrepping J, Schultze JL, Jurisica I, Schimke LF, Marques AHC, Baiocchi GC, de Souza Prado CA, Fonseca DLM, Freire PP, Rodrigues Pla?a D, Salerno Filgueiras I, Coelho Salgado R, Jansen-Marques G, Rocha Oliveira AE, Peron JPS, Cabral-Miranda G, Barbuto JAM, Camara NOS, Calich VLG, Condino-Neto A, Ulas T, Nakaya HI, Cabral-Marques O. Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States. Cells. 2022 03 01; 11(5). PMID: 35269470; PMCID: PMC8909161.
      Citations: 17     Fields:    Translation:HumansCells
    33. Temba GS, Vadaq N, Wan J, Kullaya V, Huskens D, Pecht T, Jaeger M, Boahen CK, Matzaraki V, Broeders W, Joosten LAB, Faradz SMH, Kibiki G, Middeldorp S, Cavalieri D, Lionetti P, de Groot PG, Schultze JL, Netea MG, Kumar V, de Laat B, Mmbaga BT, van der Ven AJ, Roest M, de Mast Q. Differences in thrombin and plasmin generation potential between East African and Western European adults: The role of genetic and non-genetic factors. J Thromb Haemost. 2022 05; 20(5):1089-1105. PMID: 35102686; PMCID: PMC9305795.
      Citations: 4     Fields:    Translation:Humans
    34. Katzmarski N, Cirovic B, Renieris G, Ciarlo E, Le Roy D, Theis H, Beyer M, van der Meer JWM, Joosten LAB, Schultze JL, Roger T, Giamarellos-Bourboulis EJ, Schlitzer A, Netea MG, Dom?nguez-Andr?s J, Lepikhov K, Kattler K, Gasparoni G, H?ndler K, Walter J. Reply to: 'Lack of evidence for intergenerational inheritance of immune resistance to infections'. Nat Immunol. 2022 02; 23(2):208-209. PMID: 35058615.
      Citations: 3     Fields:    
    35. Gerber JP, Russ J, Chandrasekar V, Offermann N, Lee HM, Spear S, Guzzi N, Maida S, Pattabiraman S, Zhang R, Kayvanjoo AH, Datta P, Kasturiarachchi J, Sposito T, Izotova N, Adams PD, Marafioti T, Enver T, Beyer M, Mass E, Bellodi C, Schultze JL, Capasso M, Nimmo R, Salomoni P, H?ndler K, Wenzel J. Author Correction: Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation. Nat Cell Biol. 2022 Jan; 24(1):123. PMID: 34983954; PMCID: PMC9119264.
      Citations:    Fields:    
    36. Aulakh SK, Djudjaj S, Mei HE, Schulz AR, von Stillfried S, Boor P, Nattermann J, PA-COVID-19 Study Group, Georg P, Astaburuaga-Garc?a R, Bonaguro L, Brumhard S, Michalick L, Lippert LJ, Kostevc T, G?bel C, Schneider M, Streitz M, Demichev V, Gem?nd I, Barone M, Tober-Lau P, Helbig ET, Hillus D, Petrov L, Stein J, Dey HP, Paclik D, Iwert C, M?lleder M, B?low RD, Thiel A, Hippenstiel S, Saliba AE, Eils R, Lehmann I, Mall MA, Stricker S, R?hmel J, Corman VM, Beule D, Wyler E, Landthaler M, Obermayer B, Demir M, Wesselmann H, Suttorp N, Uhrig A, M?ller-Redetzky H, Kuebler WM, Meisel C, Ralser M, Schultze JL, Aschenbrenner AC, Thibeault C, Kurth F, Sander LE, Bl?thgen N, Sawitzki B. Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Cell. 2022 02 03; 185(3):493-512.e25. PMID: 35032429; PMCID: PMC8712270.
      Citations: 75     Fields:    Translation:HumansCells
    37. Langkabel J, Horne A, Bonaguro L, Holsten L, Hesse T, Knaus A, Riedel Y, Becker M, Elmzzahi T, Bassler K, Reusch N, Yeghiazarian LH, Pecht T, Saglam A, Ulas T, Aschenbrenner AC, Kaiser F, Kubaczka C, Schultze JL, Schorle H, H?ndler K. Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs. Nat Commun. 2021 12 16; 12(1):7322. PMID: 34916498; PMCID: PMC8677818.
      Citations: 4     Fields:    Translation:AnimalsCells
    38. Gerber JP, Russ J, Chandrasekar V, Offermann N, Lee HM, Spear S, Guzzi N, Maida S, Pattabiraman S, Zhang R, Kayvanjoo AH, Datta P, Kasturiarachchi J, Sposito T, Izotova N, Adams PD, Marafioti T, Enver T, Beyer M, Mass E, Bellodi C, Schultze JL, Capasso M, Nimmo R, Salomoni P, H?ndler K, Wenzel J. Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation. Nat Cell Biol. 2021 12; 23(12):1224-1239. PMID: 34876685; PMCID: PMC8683376.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    39. von Stillfried S, Mache C, Schulze J, Djudjaj S, Geffers R, Deutsche COVID-19 OMICS Initiative (DeCOI), Herold S, Wolff T, Boor P, Wendisch D, Dietrich O, Mari T, Ibarra IL, Mittermaier M, Chua RL, Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, Mothes R, B?low RD, Leipold AM, Erhard F, Pott F, Kazmierski J, Radke J, Pergantis P, Ba?ler K, Conrad C, Aschenbrenner AC, Sawitzki B, Landthaler M, Wyler E, Horst D, Hippenstiel S, Hocke A, Heppner FL, Uhrig A, Garcia C, Machleidt F, Elezkurtaj S, Thibeault C, Witzenrath M, Cochain C, Suttorp N, Drosten C, Goffinet C, Kurth F, Schultze JL, Radbruch H, Ochs M, Eils R, M?ller-Redetzky H, Hauser AE, Luecken MD, Theis FJ, Conrad C, Selbach M, Saliba AE, Sander LE. SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis. Cell. 2021 12 22; 184(26):6243-6261.e27. PMID: 34914922; PMCID: PMC8626230.
      Citations: 153     Fields:    Translation:HumansCells
    40. Kummer MP, Ising C, Kummer C, Sarlus H, Griep A, Vieira-Saecker A, Schwartz S, Halle A, Schultze JL, Beyer M, Latz E, Heneka MT, Br?ckner M, H?ndler K. Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology. EMBO J. 2021 12 15; 40(24):e108662. PMID: 34825707; PMCID: PMC8672180.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    41. Willenborg S, Sanin DE, Ding X, Ulas T, Popovic M, MacVicar T, Langer T, Schultze JL, Gerbaulet A, Roers A, Pearce EJ, Trifunovic A, Eming SA, Jais A, N?chel J, Br?ning JC. Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab. 2021 12 07; 33(12):2398-2414.e9. PMID: 34715039.
      Citations: 47     Fields:    Translation:AnimalsCells
    42. Katzmarski N, Cirovic B, Renieris G, Ciarlo E, Le Roy D, Theis H, Beyer M, van der Meer JWM, Joosten LAB, Schultze JL, Roger T, Giamarellos-Bourboulis EJ, Schlitzer A, Netea MG, Dom?nguez-Andr?s J, Lepikhov K, Kattler K, Gasparoni G, H?ndler K, Walter J. Transmission of trained immunity and heterologous resistance to infections across generations. Nat Immunol. 2021 11; 22(11):1382-1390. PMID: 34663978.
      Citations: 37     Fields:    Translation:AnimalsCells
    43. Kern P, Balzer NR, Blank N, Cygon C, Wunderling K, Bender F, Frolov A, Sowa JP, Bonaguro L, Ulas T, Homrich M, Kiermaier E, Thiele C, Schultze JL, Canbay A, Bauer R, Mass E. Creld2 function during unfolded protein response is essential for liver metabolism homeostasis. FASEB J. 2021 10; 35(10):e21939. PMID: 34549824.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    44. Fujii W, Kapellos TS, Holsten L, Knoll R, Warnat-Herresthal S, Oestreich M, Hinkley ER, Hasenauer J, Pizarro C, Thiele C, Aschenbrenner AC, Ulas T, Skowasch D, Schultze JL, Ba?ler K, H?ndler K. Alveolar macrophage transcriptomic profiling in COPD shows major lipid metabolism changes. ERJ Open Res. 2021 Jul; 7(3). PMID: 34527724; PMCID: PMC8435801.
      Citations: 9     
    45. ToVinh M, Raabe J, Kaiser KM, Rieke GJ, Bischoff J, Monin MB, Hoffmeister C, Schlabe S, Reynolds G, Hack G, Finnemann C, Nischalke HD, Strassburg CP, Stephenson E, Su Y, Gardner L, Yuan D, Chen D, Goldman J, Rosenstiel P, Schmidt SV, Latz E, Hrusovsky K, Ball AJ, Johnson JM, Koenig PA, Schmidt FI, Haniffa M, Heath JR, Deutsche COVID-19 OMICS Initiative (DeCOI), Nattermann J, Kr?mer B, Knoll R, Bonaguro L, Astaburuaga-Garc?a R, Schulte-Schrepping J, De Domenico E, Reusch N, H?ndler K, Bl?thgen N, K?mmerer BM, Keitel V, Jensen B, Stubbemann P, Kurth F, Sander LE, Sawitzki B, Aschenbrenner AC, Schultze JL. Early IFN-a signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. Immunity. 2021 11 09; 54(11):2650-2669.e14. PMID: 34592166; PMCID: PMC8416549.
      Citations: 93     Fields:    Translation:HumansCells
    46. Embgenbroich M, van der Zande HJP, Hussaarts L, Schulte-Schrepping J, Pelgrom LR, Schlautmann L, Stoetzel I, Lambooij JM, Zawistowska-Deniziak A, Hoving L, de Ruiter K, Wijngaarden MA, Pijl H, Willems van Dijk K, Everts B, van Harmelen V, Yazdanbakhsh M, Schultze JL, Guigas B, Burgdorf S, Garc?a-Tard?n N, H?ndler K. Soluble mannose receptor induces proinflammatory macrophage activation and metaflammation. Proc Natl Acad Sci U S A. 2021 08 03; 118(31). PMID: 34326259; PMCID: PMC8346872.
      Citations: 8     Fields:    Translation:AnimalsCells
    47. Zocher S, Overall RW, Rund N, Karasinsky A, Adusumilli VS, Steinhauer C, Scheibenstock S, Schultze JL, Kempermann G, Berdugo-Vega G, H?ndler K, Calegari F. De novo DNA methylation controls neuronal maturation during adult hippocampal neurogenesis. EMBO J. 2021 09 15; 40(18):e107100. PMID: 34337766; PMCID: PMC8441477.
      Citations: 11     Fields:    Translation:AnimalsCells
    48. Knoll R, Schultze JL, Schulte-Schrepping J. Monocytes and Macrophages in COVID-19. Front Immunol. 2021; 12:720109. PMID: 34367190; PMCID: PMC8335157.
      Citations: 102     Fields:    Translation:HumansCells
    49. Oestreich M, Chen D, Schultze JL, Fritz M, Becker M. Privacy considerations for sharing genomics data. EXCLI J. 2021; 20:1243-1260. PMID: 34345236; PMCID: PMC8326502.
      Citations: 2     
    50. Divangahi M, Aaby P, Khader SA, Barreiro LB, Bekkering S, van Crevel R, Curtis N, DiNardo AR, Dominguez-Andres J, Duivenvoorden R, Fanucchi S, Fayad Z, Fuchs E, Hamon M, Jeffrey KL, Khan N, Joosten LAB, Kaufmann E, Latz E, van der Meer JWM, Mhlanga M, Moorlag SJCFM, Mulder WJM, Naik S, Novakovic B, O'Neill L, Ochando J, Ozato K, Riksen NP, Sauerwein R, Sherwood ER, Schlitzer A, Schultze JL, Sieweke MH, Benn CS, Stunnenberg H, Sun J, van de Veerdonk FL, Weis S, Williams DL, Xavier R, Netea MG, Chavakis T, Matarese G. Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes. Nat Immunol. 2021 Jul; 22(7):928. PMID: 34017127.
      Citations: 2     Fields:    
    51. Schultze H, Shastry KL, Manamohan S, Mukherjee S, Garg V, Sarveswara R, Pickkers P, Ktena S, Tran F, Herr C, Petersheim D, Behrends U, Schommers P, Lehmann C, Augustin M, Rybniker J, Mishra N, Bernardes JP, Siever C, Desai M, Monnet B, Saridaki M, Siegel CM, Schreiber S, Kim-Hellmuth S, COVID-19 Aachen Study (COVAS), Nattermann J, Skowasch D, Kurth I, Bals R, Rosenstiel P, Netea MG, Theis F, Deutsche COVID-19 Omics Initiative (DeCOI), Giamarellos-Bourboulis EJ, Kox M, Cheran S, Woodacre MS, Goh EL, Warnat-Herresthal S, H?ndler K, Aziz NA, Bitzer M, Ossowski S, Casadei N, Kern F, Fehlmann T, Altm?ller J, Kr?mer B, Bonaguro L, Schulte-Schrepping J, De Domenico E, Kraut M, Drews A, Nuesch-Germano M, Theis H, Heyckendorf J, Keller A, N?rnberg P, Rie? O, Mukherjee S, Backes M, Aschenbrenner AC, Ulas T, Breteler MMB, Becker M, Schultze JL. Swarm Learning for decentralized and confidential clinical machine learning. Nature. 2021 06; 594(7862):265-270. PMID: 34040261; PMCID: PMC8189907.
      Citations: 107     Fields:    Translation:HumansCellsPHPublic Health
    52. Mitschka S, Ulas T, Weise S, Dahm K, Becker M, Beyer M, Windhausen J, Schultze JL, Kolanus W, Torres Fern?ndez LA, H?ndler K. The stem cell-specific protein TRIM71 inhibits maturation and activity of the pro-differentiation miRNA let-7 via two independent molecular mechanisms. RNA. 2021 May 11. PMID: 33975917; PMCID: PMC8208056.
      Citations: 5     Fields:    
    53. Schultze JL. Biospektrum (Heidelb). 2021; 27(3):227. PMID: 33994671; PMCID: PMC8111368.
      Citations:    
    54. Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A, Ellenberg J, Figlerowicz M, Gasser SM, Lichter P, Linnarsson S, Marine JC, Marioni JC, Marti-Renom MA, Netea MG, Novak HR, Parkinson H, Piccolo S, Reik W, Roman-Roman S, Rosenstiel P, Schultze JL, Stegle O, Tanay A, Testa G, Thanos D, Valencia A, van Oudenaarden A, Voet T, LifeTime Community Working Groups, Rajewsky N, Almouzni G, Gorski SA, Fern?ndez XM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Nickel D, Nollmann M, Pinheiro I, Pombo A, Popp C, Theis FJ, Torres-Padilla ME, Vallot C, Vidal M. Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. 2021 Apr; 592(7852):E8. PMID: 33731935; PMCID: PMC8009763.
      Citations: 6     Fields:    
    55. Reusch N, De Domenico E, Bonaguro L, Schulte-Schrepping J, Schultze JL, Aschenbrenner AC, Ba?ler K. Neutrophils in COVID-19. Front Immunol. 2021; 12:652470. PMID: 33841435; PMCID: PMC8027077.
      Citations: 137     Fields:    Translation:HumansCellsPHPublic Health
    56. Schultze JL, Aschenbrenner AC. COVID-19 and the human innate immune system. Cell. 2021 04 01; 184(7):1671-1692. PMID: 33743212; PMCID: PMC7885626.
      Citations: 320     Fields:    Translation:HumansCells
    57. Temba GS, Kullaya V, Pecht T, Mmbaga BT, Aschenbrenner AC, Ulas T, Kibiki G, Lyamuya F, Boahen CK, Kumar V, Joosten LAB, Schultze JL, van der Ven AJ, Netea MG, de Mast Q. Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes. Nat Immunol. 2021 03; 22(3):287-300. PMID: 33574617.
      Citations: 17     Fields:    Translation:HumansCellsPHPublic Health
    58. Aschenbrenner AC, Mouktaroudi M, Oestreich M, Antonakos N, Nuesch-Germano M, Gkizeli K, Bonaguro L, Reusch N, Saridaki M, Knoll R, Pecht T, Kapellos TS, Doulou S, Herbert M, Holsten L, Horne A, Rovina N, Agrawal S, Dahm K, van Uelft M, Drews A, Lenkeit L, Bruse N, Gerretsen J, Gierlich J, Becker M, Kraut M, Theis H, Mengiste S, De Domenico E, Schulte-Schrepping J, Seep L, Raabe J, Hoffmeister C, ToVinh M, Rieke G, Talevi V, Skowasch D, Aziz NA, Pickkers P, van de Veerdonk FL, Netea MG, Schultze JL, Kox M, Breteler MMB, Nattermann J, Koutsoukou A, Giamarellos-Bourboulis EJ, Ulas T, German COVID-19 Omics Initiative (DeCOI), Kr?mer B, Ba?ler K, Kr?ger C, Gem?nd ID, H?ndler K, Keitel V. Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients. Genome Med. 2021 01 13; 13(1):7. PMID: 33441124; PMCID: PMC7805430.
      Citations: 131     Fields:    Translation:HumansCells
    59. Enderes J, Mallesh S, Schneider R, Hupa KJ, Lysson M, Schneiker B, Schlotmann B, Schultze JL, Wehner S, H?ndler K, G?nther P, Kalff JC. A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling. Front Immunol. 2020; 11:581111. PMID: 33519804; PMCID: PMC7838642.
      Citations: 4     Fields:    Translation:AnimalsCells
    60. Wang M, Yang Y, Cansever D, Wang Y, Kantores C, Chakarov S, Fijak M, Klein B, Pleuger C, Lian Z, Ma W, Liu Q, Klee K, Ulas T, Schlitzer A, Schultze JL, Becher B, Greter M, Liu Z, Ginhoux F, Epelman S, Meinhardt A, Bhushan S, Messiaen S, Moison D, Livera G, Weinberger T, Stremmel C, H?ndler K, Schulz C. Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis. Proc Natl Acad Sci U S A. 2021 01 05; 118(1). PMID: 33372158; PMCID: PMC7817195.
      Citations: 21     Fields:    Translation:AnimalsCells
    61. Divangahi M, Aaby P, Khader SA, Barreiro LB, Bekkering S, van Crevel R, Curtis N, DiNardo AR, Dominguez-Andres J, Duivenvoorden R, Fanucchi S, Fayad Z, Fuchs E, Hamon M, Jeffrey KL, Khan N, Joosten LAB, Kaufmann E, Latz E, van der Meer JWM, Mhlanga M, Moorlag SJCFM, Mulder WJM, Naik S, Novakovic B, O'Neill L, Ochando J, Ozato K, Riksen NP, Sauerwein R, Sherwood ER, Schlitzer A, Schultze JL, Sieweke MH, Benn CS, Stunnenberg H, Sun J, van de Veerdonk FL, Weis S, Williams DL, Xavier R, Netea MG, Chavakis T, Matarese G. Trained immunity, tolerance, priming and differentiation: distinct immunological processes. Nat Immunol. 2021 01; 22(1):2-6. PMID: 33293712; PMCID: PMC8020292.
      Citations: 165     Fields:    Translation:HumansAnimalsPHPublic Health
    62. De Domenico E, Bonaguro L, Schulte-Schrepping J, Becker M, Schultze JL, H?ndler K. Optimized workflow for single-cell transcriptomics on infectious diseases including COVID-19. STAR Protoc. 2020 12 18; 1(3):100233. PMID: 33377120; PMCID: PMC7757730.
      Citations: 6     Fields:    Translation:HumansCells
    63. Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Geisen U, Josephs-Spaulding J, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Bruse N, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Frey N, Friedrichs A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lindner M, Marinos G, Nattermann J, Noth R, Pickkers P, Rabe KF, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wittig M, Zimmermann J, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P, HCA Lung Biological Network, Deutsche COVID-19 Omics Initiative (DeCOI), Franzenburg J, K?hler P, K?nstner A, Brandt B, D?rr J, Dr?ger A, Franzenburg S, Fu? J, Gl?ck A, Junker R, Lier C, Markewitz R, Renz A, R?cken C, Rupp J, Wandinger KP, Busch H. Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19. Immunity. 2020 12 15; 53(6):1296-1314.e9. PMID: 33296687; PMCID: PMC7689306.
      Citations: 183     Fields:    Translation:HumansCells
    64. Bonaguro L, Schmidleithner L, Schulte-Schrepping J, Warnat-Herresthal S, Horne A, Kern P, Ter Horst R, Jaeger M, Falk CS, Li Y, Mass E, Beyer M, Joosten LAB, Netea MG, Ulas T, Schultze JL, Aschenbrenner AC, K?hne M, G?nther P, Rahmouni S, Georges M. CRELD1 modulates homeostasis of the immune system in mice and humans. Nat Immunol. 2020 12; 21(12):1517-1527. PMID: 33169013.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    65. Becker M, Schultze H, Bresniker K, Singhal S, Ulas T, Schultze JL. A novel computational architecture for large-scale genomics. Nat Biotechnol. 2020 11; 38(11):1239-1241. PMID: 32999473.
      Citations: 3     Fields:    
    66. Schulte-Schrepping J, Li X, Hatzioannou A, Dietz S, de Jesus Domingues AM, Henry I, Murray P, Schultze JL, Netea MG, Hajishengallis G, Kalafati L, Kourtzelis I, Grinenko T, Hagag E, Sinha A, Has C, Nati M, Sormendi S, Neuwirth A, Chatzigeorgiou A, Ziogas A, Lesche M, Dahl A, Subramanian P, Wielockx B, Mirtschink P, Chung KJ, Verginis P, Mitroulis I, Chavakis T. Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity. Cell. 2020 10 29; 183(3):771-785.e12. PMID: 33125892; PMCID: PMC7599076.
      Citations: 142     Fields:    Translation:AnimalsCells
    67. Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A, Ellenberg J, Figlerowicz M, Gasser SM, Lichter P, Linnarsson S, Marine JC, Marioni JC, Marti-Renom MA, Netea MG, Novak HR, Parkinson H, Piccolo S, Reik W, Roman-Roman S, Rosenstiel P, Schultze JL, Stegle O, Tanay A, Testa G, Thanos D, Valencia A, van Oudenaarden A, Voet T, LifeTime Community Working Groups, Rajewsky N, Almouzni G, Gorski SA, Fern?ndez XM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Nickel D, Nollmann M, Pinheiro I, Pombo A, Popp C, Theis FJ, Torres-Padilla ME, Vallot C, Vidal M. LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. 2020 11; 587(7834):377-386. PMID: 32894860; PMCID: PMC7656507.
      Citations: 57     Fields:    Translation:Humans
    68. Rabold K, Aschenbrenner A, Thiele C, Boahen CK, Schiltmans A, Smit JWA, Schultze JL, Netea MG, Adema GJ, Netea-Maier RT. Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics. J Immunother Cancer. 2020 09; 8(2). PMID: 32943450; PMCID: PMC7500191.
      Citations: 22     Fields:    Translation:HumansCells
    69. Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Sander J, Lehmann C, Thabet Y, Schmidleithner L, Trebicka J, Schierwagen R, Hofmann A, Popov A, Lang KS, Kurts C, Hartmann P, Knolle PA, Schultze JL, Shinde PV, K?hne M, Oxenius A, Buch T, Heikenwalder M, F?tkenheuer G, Lang PA. Publisher Correction: Tumor-necrosis factor impairs CD4+ T cell-mediated immunological control in chronic viral infection. Nat Immunol. 2020 Sep; 21(9):1135. PMID: 32620862.
      Citations:    Fields:    
    70. Willers M, Ulas T, Heinemann AS, Pirr S, Fehlhaber B, Halle O, Schreek S, Hombach P, Basic M, Bleich A, Cloppenborg-Schmidt K, Jonigk D, Hansen G, Schultze JL, Viemann D, V?llger L, Vogl T, Pagel J, Sch?ning J, L?ber U, Essex M, Graspeuntner S, K?nzel S, Rupp J, F?rster R, Baines JF, H?rtel C, Forslund SK, Roth J. S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants. Gastroenterology. 2020 12; 159(6):2130-2145.e5. PMID: 32805279.
      Citations: 41     Fields:    Translation:HumansAnimals
    71. Schulte-Schrepping J, Reusch N, Zhang B, Bonaguro L, De Domenico E, Grasshoff M, Kapellos TS, Beckstette M, Pecht T, Saglam A, Mei HE, Schulz AR, Xu CJ, Horne A, Herbert M, Drews A, Raabe J, Kaiser KM, Vinh MT, Rieke G, Ulas T, Becker M, Geffers R, Schultze JL, Aschenbrenner AC, Li Y, Nattermann J, Deutsche COVID-19 OMICS Initiative (DeCOI), Paclik D, Ba?ler K, Schlickeiser S, Kr?mer B, Krammer T, Brumhard S, Wendisch D, Dietrich O, Conrad C, Kunkel D, Vafadarnejad E, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, M?ller-Redetzky H, Heim KM, Machleidt F, Uhrig A, Bosquillon de Jarcy L, J?rgens L, Stegemann M, Gl?senkamp CR, Volk HD, Goffinet C, Landthaler M, Wyler E, Georg P, Schneider M, Dang-Heine C, Neuwinger N, Kappert K, Tauber R, Corman V, Meisel C, Witzenrath M, Drosten C, Suttorp N, von Kalle C, Kurth F, H?ndler K, Sawitzki B, Saliba AE, Sander LE. Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment. Cell. 2020 09 17; 182(6):1419-1440.e23. PMID: 32810438; PMCID: PMC7405822.
      Citations: 712     Fields:    Translation:HumansCellsPHPublic Health
    72. Neubert P, Homann A, Wendelborn D, Krampert L, Trum M, Ebner S, Weichselbaum A, Schatz V, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Kunzelmann K, Hammer K, Binger KJ, Titze J, Kolanus W, Schultze JL, Wagner S, Jantsch J, B?r AL, Schr?der A, Linz P, Geisberger S, M?ller DN. NCX1 represents an ionic Na+ sensing mechanism in macrophages. PLoS Biol. 2020 06; 18(6):e3000722. PMID: 32569301; PMCID: PMC7307728.
      Citations: 13     Fields:    Translation:AnimalsCells
    73. Cirovic B, de Bree LCJ, Groh L, Blok BA, Chan J, van der Velden WJFM, Bremmers MEJ, van Crevel R, Picelli S, Schulte-Schrepping J, Klee K, Oosting M, Koeken VACM, van Ingen J, Li Y, Benn CS, Schultze JL, Joosten LAB, Curtis N, Netea MG, Schlitzer A, H?ndler K. BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment. Cell Host Microbe. 2020 08 12; 28(2):322-334.e5. PMID: 32544459; PMCID: PMC7295478.
      Citations: 164     Fields:    Translation:HumansCellsPHPublic Health
    74. Fischer-Riepe L, Daber N, Schulte-Schrepping J, Russo A, Pohlen M, Fischer J, Chasan AI, Wolf M, Ulas T, Glander S, Skryabin B, Wollbrink Dipl-Ing A, Steingraeber N, Vettorazzi S, Holzinger D, Gross J, Rosenbauer F, Stoll M, Niemann S, Tuckermann J, Schultze JL, Roth J, Barczyk-Kahlert K, V?ras De Carvalho BC, Schulz C, Stremmel C, Koehle M, G?rtner F. CD163 expression defines specific, IRF8-dependent, immune-modulatory macrophages in the bone marrow. J Allergy Clin Immunol. 2020 11; 146(5):1137-1151. PMID: 32199911.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    75. Georganaki M, Ramachandran M, Tuit S, Karampatzakis A, Fotaki G, van Hooren L, Huang H, Lugano R, Ulas T, Kaunisto A, Holland EC, Ellmark P, Mangsbo SM, Schultze J, Essand M, Tugues S, Dimberg A, N??ez NG. Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy. Oncoimmunology. 2020; 9(1):1730538. PMID: 32231867; PMCID: PMC7094447.
      Citations: 19     Fields:    Translation:AnimalsCells
    76. Netea MG, Barreiro LB, Chavakis T, Divangahi M, Fuchs E, Joosten LAB, van der Meer JWM, Mhlanga MM, Mulder WJM, Riksen NP, Schlitzer A, Schultze JL, Stabell Benn C, Sun JC, Xavier RJ, Latz E, Dom?nguez-Andr?s J. Defining trained immunity and its role in health and disease. Nat Rev Immunol. 2020 06; 20(6):375-388. PMID: 32132681; PMCID: PMC7186935.
      Citations: 789     Fields:    Translation:HumansAnimals
    77. Werner Y, Mass E, Ashok Kumar P, Ulas T, Horne A, Klee K, Lupp A, Saaber F, Redecker C, Schultze JL, Geissmann F, Stumm R, H?ndler K, Sch?tz D. Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke. Nat Neurosci. 2020 03; 23(3):351-362. PMID: 32042176; PMCID: PMC7523735.
      Citations: 81     Fields:    Translation:AnimalsCells
    78. Liepelt A, Hohlstein P, Gussen H, Xue J, Aschenbrenner AC, Ulas T, Buendgens L, Warzecha KT, Bartneck M, Luedde T, Trautwein C, Schultze JL, Koch A, Tacke F. Differential Gene Expression in Circulating CD14+ Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis. J Clin Med. 2020 Jan 02; 9(1). PMID: 31906585; PMCID: PMC7019484.
      Citations: 7     
    79. Warnat-Herresthal S, Perrakis K, Taschler B, Becker M, Beyer M, Schulte-Schrepping J, Seep L, Klee K, Ulas T, Mukherjee S, Schultze JL, Ba?ler K, G?nther P, Haferlach T. Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics. iScience. 2020 Jan 24; 23(1):100780. PMID: 31918046; PMCID: PMC6992905.
      Citations: 22     
    80. Schultze JL. Specificity meets function. Nat Immunol. 2019 12; 20(12):1565-1567. PMID: 31745339.
      Citations:    Fields:    Translation:Cells
    81. Camell CD, Lee A, Goldberg EL, Spadaro O, Youm YH, Bartke A, Hubbard GB, Ikeno Y, Ruddle NH, Schultze J, Dixit VD, G?nther P. Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis. Cell Metab. 2019 12 03; 30(6):1024-1039.e6. PMID: 31735593; PMCID: PMC6944439.
      Citations: 75     Fields:    Translation:AnimalsCells
    82. Tuit S, Salvagno C, Kapellos TS, Hau CS, Seep L, Oestreich M, Klee K, de Visser KE, Ulas T, Schultze JL. Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients. Cell Rep. 2019 10 29; 29(5):1221-1235.e5. PMID: 31665635; PMCID: PMC7057267.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    83. Schultze JL, G?nther P. Mind the Map: Technology Shapes the Myeloid Cell Space. Front Immunol. 2019; 10:2287. PMID: 31636632; PMCID: PMC6787770.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    84. Kapellos TS, Bonaguro L, Reusch N, Saglam A, Hinkley ER, Schultze JL, Gem?nd I. Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases. Front Immunol. 2019; 10:2035. PMID: 31543877; PMCID: PMC6728754.
      Citations: 324     Fields:    Translation:HumansAnimalsCells
    85. Placek K, Schultze JL, Aschenbrenner AC. Epigenetic reprogramming of immune cells in injury, repair, and resolution. J Clin Invest. 2019 07 22; 129(8):2994-3005. PMID: 31329166; PMCID: PMC6668667.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    86. Sundararajan Z, Knoll R, Hombach P, Schultze JL, Ulas T, Becker M. Shiny-Seq: advanced guided transcriptome analysis. BMC Res Notes. 2019 Jul 18; 12(1):432. PMID: 31319888; PMCID: PMC6637470.
      Citations: 13     Fields:    Translation:HumansCells
    87. Sloot YJE, Rabold K, Ulas T, De Graaf DM, Heinhuis B, Schultze JL, Netea MG, Smit JWA, Joosten LAB, Netea-Maier RT, H?ndler K. Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration. Cell Oncol (Dordr). 2019 Oct; 42(5):691-703. PMID: 31201646.
      Citations: 8     Fields:    Translation:HumansCells
    88. Placek K, Schultze JL, Netea MG. Immune memory characteristics of innate lymphoid cells. Curr Opin Infect Dis. 2019 06; 32(3):196-203. PMID: 31021952.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    89. Schmidleithner L, Thabet Y, Sommer D, Abdullah Z, Sadlon T, Osei-Sarpong C, Subbaramaiah K, Copperi F, Haendler K, Varga T, Schanz O, Bourry S, Bassler K, Krebs W, Peters AE, Baumgart AK, Schneeweiss M, Klee K, Schmidt SV, Sander J, Ohkura N, Waha A, Sparwasser T, Wunderlich FT, Ulas T, Weighardt H, Sakaguchi S, Pfeifer A, Dannenberg AJ, Muglia LJ, Wickenhauser C, Barry SC, Schultze JL, Beyer M, Sch?nfeld E, K?hne M, N?ssing S, F?rster I, Bl?her M, Ferreir?s N. Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. Immunity. 2019 05 21; 50(5):1232-1248.e14. PMID: 31027998.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    90. Goossens P, Rodriguez-Vita J, Etzerodt A, Masse M, Rastoin O, Gouirand V, Ulas T, Papantonopoulou O, Van Eck M, Auphan-Anezin N, Bebien M, Verthuy C, Vu Manh TP, Turner M, Dalod M, Schultze JL, Lawrence T. Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression. Cell Metab. 2019 06 04; 29(6):1376-1389.e4. PMID: 30930171.
      Citations: 162     Fields:    Translation:AnimalsCells
    91. Civit L, Frey F, Weber H, Lingnau A, Blank M, Stunden J, Latz E, Kubbutat MHG, Theodorou I, Gr?ber C, Dambrune C, Beyer M, Schultze J, Ducong? F, Mayer G. Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model. Sci Rep. 2019 03 21; 9(1):4976. PMID: 30899039; PMCID: PMC6428855.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    92. Salvagno C, Ciampricotti M, Tuit S, Hau CS, van Weverwijk A, Coffelt SB, Kersten K, Vrijland K, Kos K, Ulas T, Song JY, Ooi CH, Jonkers J, Schultze JL, Ries CH, de Visser KE, R?ttinger D, Cassier PA. Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response. Nat Cell Biol. 2019 04; 21(4):511-521. PMID: 30886344; PMCID: PMC6451630.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    93. van der Poel M, Mizee MR, Hsiao CC, Miedema SSM, Schuurman KG, Helder B, Tas SW, Huitinga I, Ulas T, Schultze JL, Hamann J. Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes. Nat Commun. 2019 03 13; 10(1):1139. PMID: 30867424; PMCID: PMC6416318.
      Citations: 131     Fields:    Translation:HumansCells
    94. Schultze JL, Mass E, Schlitzer A. Emerging Principles in Myelopoiesis at Homeostasis and during Infection and Inflammation. Immunity. 2019 02 19; 50(2):288-301. PMID: 30784577.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    95. Zwick M, Ulas T, Ried C, Grosse L, Simon C, Bernhard C, Schultze JL, Stutte S, Brocker T, Cho YL, Busch DH, Buchholz VR. Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells. Front Immunol. 2019; 10:222. PMID: 30809231; PMCID: PMC6379467.
      Citations: 1     Fields:    Translation:AnimalsCells
    96. Bassler K, Schulte-Schrepping J, Warnat-Herresthal S, Aschenbrenner AC, Schultze JL. The Myeloid Cell Compartment-Cell by Cell. Annu Rev Immunol. 2019 04 26; 37:269-293. PMID: 30649988.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    97. Netea MG, Schlitzer A, Placek K, Joosten LAB, Schultze JL. Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens. Cell Host Microbe. 2019 01 09; 25(1):13-26. PMID: 30629914.
      Citations: 178     Fields:    Translation:HumansAnimalsCells
    98. Schultze JL. Myocardial infarction cell by cell. Nat Immunol. 2019 01; 20(1):7-9. PMID: 30538327.
      Citations: 4     Fields:    Translation:HumansCells
    99. Rakers C, Schleif M, Blank N, Ulas T, Torres SV, Schumacher T, Tai K, Schultze JL, Jackson WS, Petzold GC, Matu?kov? H, H?ndler K. Stroke target identification guided by astrocyte transcriptome analysis. Glia. 2019 04; 67(4):619-633. PMID: 30585358.
      Citations: 54     Fields:    Translation:AnimalsCells
    100. Tasouri E, Ulas T, Zenz T, Bullinger L, Schultze JL, Kabrani E, Chu VT, Sommermann T, Ba?ler K, Rajewsky K, Sander S. Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells. Blood. 2018 12 20; 132(25):2670-2683. PMID: 30333121.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    101. Ravussin A, Youm YH, Sander J, Ryu S, Nguyen K, Varela L, Shulman GI, Sidorov S, Horvath TL, Schultze JL, Dixit VD. Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity. Cell Rep. 2018 07 31; 24(5):1085-1092.e6. PMID: 30067966; PMCID: PMC6223120.
      Citations: 9     Fields:    Translation:AnimalsCells
    102. Pfeiffer F, Blank M, Beyer M, Schultze JL, Gr?ber C, H?ndler K, Mayer G. Systematic evaluation of error rates and causes in short samples in next-generation sequencing. Sci Rep. 2018 Jul 19; 8(1):10950. PMID: 30026539; PMCID: PMC6053417.
      Citations: 128     Fields:    
    103. Doebbeler M, Koenig C, Krzyzak L, Seitz C, Wild A, Ulas T, Kopelyanskiy D, Butterhof A, Kuhnt C, Kreiser S, Stich L, Zinser E, Knippertz I, Wirtz S, Riegel C, Hoffmann P, Edinger M, Schultze JL, Steinkasserer A, Lechmann M, Ba?ler K, Nitschke L, Winkler T. CD83 expression is essential for Treg cell differentiation and stability. JCI Insight. 2018 06 07; 3(11). PMID: 29875316; PMCID: PMC6124443.
      Citations: 28     Fields:    Translation:AnimalsCells
    104. Schultze JL, SYSCID consortium, Rosenstiel P. Systems Medicine in Chronic Inflammatory Diseases. Immunity. 2018 04 17; 48(4):608-613. PMID: 29669240.
      Citations: 13     Fields:    Translation:Humans
    105. Ulas T, Baines JF, Schultze JL, Pan WH, Sommer F, Falk-Paulsen M, Best P, Fazio A, Kachroo P, Luzius A, Jentzsch M, Rehman A, M?ller F, Lengauer T, Walter J, K?nzel S, Schreiber S, Franke A, B?ckhed F, Rosenstiel P. Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development. Genome Med. 2018 04 13; 10(1):27. PMID: 29653584; PMCID: PMC5899322.
      Citations: 69     Fields:    Translation:AnimalsCells
    106. Ulas T, Blank T, Staszewski O, Datta M, Schultze JL, Beyer M, Prinz M, Wendeln AC, Degenhardt K, Kaurani L, Gertig M, Jain G, Wagner J, H?sler LM, Wild K, Skodras A, Centeno TP, Capece V, Islam MR, Kerimoglu C, Staufenbiel M, Jucker M, Fischer A, Neher JJ. Innate immune memory in the brain shapes neurological disease hallmarks. Nature. 2018 04; 556(7701):332-338. PMID: 29643512; PMCID: PMC6038912.
      Citations: 360     Fields:    Translation:HumansAnimalsCells
    107. Bickert A, Kern P, van Uelft M, Herresthal S, Ulas T, Gutbrod K, Breiden B, Degen J, Sandhoff K, Schultze JL, Hartmann D, Bauer R, Willecke K, D?rmann P. Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 07; 1863(7):734-749. PMID: 29653252.
      Citations: 4     Fields:    Translation:Animals
    108. Vogl T, Stratis A, Thurainayagam S, Jorch SK, Zenker S, Chakraborty D, Paruzel P, Wehmeyer C, Papantonopoulou O, Stoll M, Leanderson T, Schultze JL, Pap T, Roth J, Wixler V, V?ller T, Dreiling A, Fr?hling M, Hermann S, Geyer C, Loser K, Sch?fers M, Ludwig S, K?nig S. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018 05 01; 128(5):1852-1866. PMID: 29611822; PMCID: PMC5919817.
      Citations: 83     Fields:    Translation:AnimalsCells
    109. Schultze JL, Aschenbrenner AC. Systems immunology allows a new view on human dendritic cells. Semin Cell Dev Biol. 2019 02; 86:15-23. PMID: 29448068.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    110. Kapellos TS, Bassler K, Aschenbrenner AC, Fujii W, Schultze JL. Dysregulated Functions of Lung Macrophage Populations in COPD. J Immunol Res. 2018; 2018:2349045. PMID: 29670919; PMCID: PMC5835245.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    111. Gulei D, Irimie AI, Cojocneanu-Petric R, Schultze JL, Berindan-Neagoe I. Exosomes-Small Players, Big Sound. Bioconjug Chem. 2018 03 21; 29(3):635-648. PMID: 29369619.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    112. Sociale M, Wulf AL, Klee K, Thielisch M, Eckardt F, Sellin J, Weinstock N, Schultze J, Bauer R, Breiden B, B?low MH, L?bbert S, Voelzmann A, Sandhoff K. Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements. Cell Rep. 2018 01 23; 22(4):967-978. PMID: 29386138.
      Citations: 23     Fields:    Translation:Animals
    113. Wang B, Eugster A, Schlitzer A, Beyer M, Joosten LAB, Isermann B, Simons K, Henry I, Schultze JL, Zamboni N, Hajishengallis G, Netea MG, Mitroulis I, Ruppova K, Chen LS, Grzybek M, Grinenko T, Troullinaki M, Palladini A, Kourtzelis I, Chatzigeorgiou A, Lesche M, Petzold A, Dahl A, Wielockx B, Mirtschink P, Coskun ?, Chavakis T. Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell. 2018 01 11; 172(1-2):147-161.e12. PMID: 29328910; PMCID: PMC5766828.
      Citations: 414     Fields:    Translation:AnimalsCells
    114. Christ A, Lauterbach MAR, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E, G?nther P, Duewell P, Ba?ler K. Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell. 2018 01 11; 172(1-2):162-175.e14. PMID: 29328911; PMCID: PMC6324559.
      Citations: 409     Fields:    Translation:HumansAnimalsCells
    115. Ulas T, Schultze JL, Beyer M. Bioinformatic Assessment of Macrophage Activation by the Innate Immune System. Methods Mol Biol. 2018; 1714:19-40. PMID: 29177853.
      Citations:    Fields:    Translation:HumansCells
    116. Low D, Silvin A, Chen J, Schulte-Schrepping J, Blecher R, Ulas T, David FS, Scholz C, Shihui F, Lum J, Amoyo AA, Larbi A, Poidinger M, Buttgereit A, Greter M, Chan JKY, Amit I, Beyer M, Schultze JL, Schlitzer A, Pettersson S, Ginhoux F, Thion MS, Grisel P, Squarzoni P, Hoeffel G, Coulpier F, Siopi E, Lledo PM, Garel S. Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner. Cell. 2018 01 25; 172(3):500-516.e16. PMID: 29275859; PMCID: PMC5786503.
      Citations: 312     Fields:    Translation:HumansAnimalsCells
    117. Sander J, Schmidt SV, Cirovic B, McGovern N, Papantonopoulou O, Hardt AL, Aschenbrenner AC, Kreer C, Quast T, Xu AM, Schmidleithner LM, Theis H, Thi Huong LD, Sumatoh HRB, Lauterbach MAR, Schulte-Schrepping J, Xue J, Ulas T, Klee K, Katzmarski N, Herresthal S, Krebs W, Martin B, Latz E, Kraut M, Kolanus W, Beyer M, Falk CS, Wiegmann B, Burgdorf S, Melosh NA, Newell EW, Ginhoux F, Schlitzer A, Schultze JL, G?nther P, Ba?ler K, H?ndler K. Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2. Immunity. 2017 12 19; 47(6):1051-1066.e12. PMID: 29262348; PMCID: PMC5772172.
      Citations: 71     Fields:    Translation:HumansCells
    118. Wischhof L, Maida S, Piazzesi A, Gioran A, Barragan Sanz K, Irsen S, Beyer M, Schultze JL, Dyer MJ, Salomoni P, Ehninger D, Nicotera P, Bano D. The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function. Sci Rep. 2017 12 06; 7(1):17055. PMID: 29213114; PMCID: PMC5719005.
      Citations: 3     Fields:    Translation:AnimalsCells
    119. Civit L, Taghdisi SM, Jonczyk A, Blank M, Stunden HJ, Latz E, Ha?el SK, Gr?ber C, Beyer M, Schultze J, Mayer G. Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells. Biochimie. 2018 Feb; 145:53-62. PMID: 29054799.
      Citations: 22     Fields:    Translation:HumansCells
    120. Blank M, F?lle L, Steiner N, Funke M, Gondorf F, Pfeiffer F, Siegl J, Opitz FV, Ha?el SK, Erazo AB, Schanz O, Stunden HJ, Gr?ber C, H?ndler K, Beyer M, Weighardt H, Latz E, Schultze JL, Mayer G, F?rster I. RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In?Vivo. Mol Ther. 2018 01 03; 26(1):95-104. PMID: 29103909; PMCID: PMC5763148.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    121. Camell CD, Sander J, Spadaro O, Lee A, Nguyen KY, Wing A, Goldberg EL, Youm YH, Brown CW, Elsworth J, Rodeheffer MS, Schultze JL, Dixit VD. Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. Nature. 2017 10 05; 550(7674):119-123. PMID: 28953873; PMCID: PMC5718149.
      Citations: 199     Fields:    Translation:AnimalsCells
    122. Ulas T, Pirr S, Fehlhaber B, Bickes MS, Loof TG, Vogl T, Mellinger L, Heinemann AS, Burgmann J, Schreek S, Pfeifer S, Reuner F, Stanulla M, Glander S, Barczyk-Kahlert K, von Kaisenberg CS, Friesenhagen J, Fischer-Riepe L, Zenker S, Schultze JL, Roth J, Viemann D, Sch?ning J, V?llger L, von K?ckritz-Blickwede M. Corrigendum: S100-alarmin-induced innate immune programming protects newborn infants from sepsis. Nat Immunol. 2017 09 19; 18(10):1173. PMID: 28926540.
      Citations: 1     Fields:    
    123. Quasdorff M, Kashkar H, Debey-Pascher S, Arzberger S, Webb D, von Olshausen G, Schultze JL, H?sel M, Ringelhan M, Sprinzl MF, Bockmann JH, Weber A, B?ning H, Heikenwalder M, Protzer U. Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication. Cell Mol Gastroenterol Hepatol. 2017 Nov; 4(3):339-363. PMID: 28884137; PMCID: PMC5581872.
      Citations: 17     Fields:    
    124. Aschenbrenner AC, Bassler K, Brondolin M, Bonaguro L, Carrera P, Klee K, Ulas T, Schultze JL, Hoch M. A cross-species approach to identify transcriptional regulators exemplified for Dnajc22 and Hnf4a. Sci Rep. 2017 06 22; 7(1):4056. PMID: 28642491; PMCID: PMC5481429.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    125. Bilkei-Gorzo A, Albayram O, Draffehn A, Michel K, Piyanova A, Oppenheimer H, Dvir-Ginzberg M, Ulas T, Imbeault S, Bab I, Schultze JL, Zimmer A, R?cz I. A chronic low dose of ?9-tetrahydrocannabinol (THC) restores cognitive function in old mice. Nat Med. 2017 Jun; 23(6):782-787. PMID: 28481360.
      Citations: 94     Fields:    Translation:AnimalsCells
    126. See P, Dutertre CA, Chen J, McGovern N, Irac SE, Gunawan M, Beyer M, Duan K, Sumatoh HRB, Ruffin N, Jouve M, Hennekam RCM, Lim T, Yip CC, Wen M, Malleret B, Low I, Shadan NB, Fen CFS, Tay A, Lum J, Zolezzi F, Larbi A, Poidinger M, Chan JKY, Chen Q, Haniffa M, Benaroch P, Schlitzer A, Schultze JL, Newell EW, Ginhoux F, G?nther P, H?ndler K, Gea-Mallorqu? E, R?nia L. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017 06 09; 356(6342). PMID: 28473638; PMCID: PMC7611082.
      Citations: 241     Fields:    Translation:HumansCells
    127. Ulas T, Pirr S, Fehlhaber B, Bickes MS, Loof TG, Mellinger L, Heinemann AS, Burgmann J, Schreek S, Pfeifer S, Reuner F, Stanulla M, von Kaisenberg CS, Friesenhagen J, Schultze JL, Viemann D, Vogl T, Sch?ning J, V?llger L, von K?ckritz-Blickwede M, Glander S, Barczyk-Kahlert K, Fischer-Riepe L, Zenker S, Roth J. S100-alarmin-induced innate immune programming protects newborn infants from sepsis. Nat Immunol. 2017 06; 18(6):622-632. PMID: 28459433.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    128. Sander J, Schultze JL, Yosef N. ImpulseDE: detection of differentially expressed genes in time series data using impulse models. Bioinformatics. 2017 03 01; 33(5):757-759. PMID: 27797772; PMCID: PMC5859984.
      Citations: 21     Fields:    Translation:AnimalsCells
    129. Heine A, Held SAE, Schulte-Schrepping J, Wolff JFA, Klee K, Ulas T, Schmacke NA, Daecke SN, Riethausen K, Schultze JL, Brossart P. Generation and functional characterization of MDSC-like cells. Oncoimmunology. 2017; 6(4):e1295203. PMID: 28507805; PMCID: PMC5414884.
      Citations: 24     Fields:    
    130. Aschenbrenner AC, Schultze JL. New "programmers" in tissue macrophage activation. Pflugers Arch. 2017 04; 469(3-4):375-383. PMID: 28185067.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    131. Sander J, Lux A, Hartmann A, Ulas T, McGovern N, Spriewald B, Mackensen A, Schuler G, Schauf B, Forster A, Fasching PA, Purbojo A, Cesnjevar R, Ullrich E, Ginhoux F, Schlitzer A, Nimmerjahn F, Schultze JL, Heidkamp GF, Lehmann CHK, Heger L, Eissing N, Baranska A, L?hr JJ, Hoffmann A, Reimer KC, S?der S, Zenk J, Alexiou C, Repp R, Dudziak D. Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment. Sci Immunol. 2016 Dec 16; 1(6). PMID: 28783692.
      Citations: 71     Fields:    
    132. Durek P, Kressler C, de Almeida M, Bassler K, Ulas T, Sinha A, Kinkley S, Yang X, Arrigoni L, Feuerbach L, Gorka O, Li N, Frischbutter S, Cendon C, Imbusch CD, Hutter B, Zipprich G, Reinke S, Hoffmann U, Richter AS, Sieverling L, DEEP Consortium, Chang HD, Brors B, Manke T, Dong J, Chung HR, Rosenstiel P, Schultze JL, Radbruch A, Hamann A, Polansky JK, Nordstr?m K, Gasparoni G, Salhab A, Schmidt F, Xiong J, Gla?ar P, Klironomos F, Amirabad AD, Ardakani FB, Ebert P, M?ller F, Schlickeiser S, Fr?hler S, Felder B, Gasparoni N, Tauchmann Y, Wassilew G, Syrbe U, Kalus U, Eils J, Ruland J, Lengauer T, Rajewsky N, Chen W, Sawitzki B, Schulz MH, Walter J. Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development. Immunity. 2016 11 15; 45(5):1148-1161. PMID: 27851915.
      Citations: 100     Fields:    Translation:HumansCells
    133. Schultze JL. Chromatin Remodeling in Monocyte and Macrophage Activation. Adv Protein Chem Struct Biol. 2017; 106:1-15. PMID: 28057208.
      Citations: 6     Fields:    Translation:HumansCells
    134. Schlitzer A, Schultze JL. Tissue-resident macrophages - how to humanize our knowledge. Immunol Cell Biol. 2017 02; 95(2):173-177. PMID: 27752049.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    135. Tedeschi A, Dupraz S, Laskowski CJ, Xue J, Ulas T, Beyer M, Schultze JL, Bradke F. The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS. Neuron. 2016 Oct 19; 92(2):419-434. PMID: 27720483.
      Citations: 121     Fields:    Translation:AnimalsCells
    136. Arts RJ, Plantinga TS, Tuit S, Ulas T, Heinhuis B, Tesselaar M, Sloot Y, Adema GJ, Joosten LA, Smit JW, Netea MG, Schultze JL, Netea-Maier RT. Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages. Oncoimmunology. 2016; 5(12):e1229725. PMID: 28123869; PMCID: PMC5213309.
      Citations: 50     Fields:    
    137. Schuette V, Embgenbroich M, Ulas T, Welz M, Schulte-Schrepping J, Draffehn AM, Quast T, Koch K, Nehring M, Zweynert A, Harms FL, Steiner N, Limmer A, Berberich-Siebelt F, Kolanus W, Beyer M, Schultze JL, Burgdorf S, K?nig J, F?rster I, Knolle PA, Wohlleber D. Mannose receptor induces T-cell tolerance via inhibition of CD45 and up-regulation of CTLA-4. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):10649-54. PMID: 27601670; PMCID: PMC5035904.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    138. Mass E, Ballesteros I, Farlik M, Halbritter F, Crozet L, Jacome-Galarza CE, Klughammer J, Kobayashi Y, Gomez-Perdiguero E, Schultze JL, Beyer M, Bock C, Geissmann F, G?nther P, H?ndler K. Specification of tissue-resident macrophages during organogenesis. Science. 2016 09 09; 353(6304). PMID: 27492475; PMCID: PMC5066309.
      Citations: 341     Fields:    Translation:AnimalsCells
    139. Schultze JL. Macrophage tolerance in the gut: It is in the epigenome! Eur J Immunol. 2016 08; 46(8):1838-41. PMID: 27518699.
      Citations: 1     Fields:    
    140. Szulzewsky F, Arora S, de Witte L, Ulas T, Markovic D, Schultze JL, Holland EC, Synowitz M, Wolf SA, Kettenmann H. Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples. Glia. 2016 08; 64(8):1416-36. PMID: 27312099.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    141. Kroy D, Hackstein CP, Assmus LM, Welz M, Klein S, Schwandt T, Schultze J, F?rster I, Gondorf F, Beyer M, Kurts C, Trebicka J, Kastenm?ller W, Knolle PA, Abdullah Z. Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis. Gut. 2017 03; 66(3):507-518. PMID: 27432540.
      Citations: 38     Fields:    Translation:AnimalsCells
    142. Hagemeyer N, Kierdorf K, Frenzel K, Xue J, Abdullah Z, Wieghofer P, Ulas T, Rosenbauer F, Schultze JL, Prinz M, Ringelhan M, Godin I, Costa Jord?o MJ, Yorgancioglu G, Knolle PA, Heikenwalder M. Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation. EMBO J. 2016 08 15; 35(16):1730-44. PMID: 27412700; PMCID: PMC5010043.
      Citations: 63     Fields:    Translation:AnimalsCells
    143. Mori T, Maruyama T, Takeyama H, Brandst?tter O, Schanz O, Vorac J, K?nig J, Korkowski M, Haarmann-Stemmann T, von Smolinski D, Schultze JL, Abel J, Esser C, Weighardt H, F?rster I. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016 05 17; 6:26091. PMID: 27184933; PMCID: PMC4869119.
      Citations: 37     Fields:    Translation:Animals
    144. Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Latz E, Bj?rkhem I, Gustafsson J?, L?tjohann D. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Sci Transl Med. 2016 Apr 06; 8(333):333ra50. PMID: 27053774; PMCID: PMC4878149.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    145. Schultze JL, Schmidt SV. Molecular features of macrophage activation. Semin Immunol. 2015 12; 27(6):416-23. PMID: 27049460.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    146. Shahbazi E, Moradi S, Nemati S, Satarian L, Basiri M, Gourabi H, Zare Mehrjardi N, Hatay FF, Molcanyi M, Schultze JL, Saric T, Baharvand H, G?nther P, Lampert A, H?ndler K, Schmidt D, Hescheler J. Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor. Stem Cell Reports. 2016 Apr 12; 6(4):539-551. PMID: 27052315; PMCID: PMC4834053.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    147. Beins E, Ulas T, Ternes S, Neumann H, Schultze JL, Zimmer A. Characterization of inflammatory markers and transcriptome profiles of differentially activated embryonic stem cell-derived microglia. Glia. 2016 Jun; 64(6):1007-20. PMID: 26959607.
      Citations: 13     Fields:    Translation:AnimalsCells
    148. Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Sander J, Lehmann C, Thabet Y, Schmidleithner L, Trebicka J, Schierwagen R, Hofmann A, Popov A, Lang KS, Kurts C, Hartmann P, Knolle PA, Schultze JL, Shinde PV, K?hne M, Oxenius A, Buch T, Heikenwalder M, F?tkenheuer G, Lang PA. Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infection. Nat Immunol. 2016 May; 17(5):593-603. PMID: 26950238.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    149. Deng M, Perner S, Br?gelmann J, Schultze JL. Web-TCGA: an online platform for integrated analysis of molecular cancer data sets. BMC Bioinformatics. 2016 Feb 06; 17:72. PMID: 26852330; PMCID: PMC4744375.
      Citations: 85     Fields:    Translation:Humans
    150. Schultze JL, Beyer M. Myelopoiesis Reloaded: Single-Cell Transcriptomics Leads the Way. Immunity. 2016 Jan 19; 44(1):18-20. PMID: 26789920.
      Citations: 2     Fields:    Translation:AnimalsCells
    151. Schmidt SV, Krebs W, Ulas T, Xue J, Hardt AL, Sander J, Klee K, Theis H, Kraut M, Beyer M, Schultze JL, Ba?ler K, G?nther P, Schultze H. The transcriptional regulator network of human inflammatory macrophages is defined by open chromatin. Cell Res. 2016 Feb; 26(2):151-70. PMID: 26729620; PMCID: PMC4746609.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    152. Ginhoux F, Schultze JL, Murray PJ, Ochando J, Biswas SK. New insights into the multidimensional concept of macrophage ontogeny, activation and function. Nat Immunol. 2016 Jan; 17(1):34-40. PMID: 26681460.
      Citations: 338     Fields:    Translation:HumansAnimalsCells
    153. Sorg UR, Behnke K, Degrandi D, Reich M, Keitel V, Herebian D, Beyer M, Schultze JL, Gabbert HE, Mayatepek E, Pfeffer K, Deenen R, K?hrer K, H?ussinger D. Cooperative role of lymphotoxin ? receptor and tumor necrosis factor receptor p55 in murine liver regeneration. J Hepatol. 2016 May; 64(5):1108-1117. PMID: 26708145.
      Citations: 7     Fields:    Translation:AnimalsCells
    154. Milanez-Almeida P, Ulas T, Pasztoi M, Glage S, Schughart K, Schultze JL, Huehn J, Lutz MB. CD11b(+)Ly6C(++)Ly6G(-) Cells with Suppressive Activity Towards T Cells Accumulate in Lungs of Influenza a Virus-Infected Mice. Eur J Microbiol Immunol (Bp). 2015 Dec; 5(4):246-55. PMID: 26716013; PMCID: PMC4681352.
      Citations: 2     
    155. Sistigu A, Semeraro M, De Ninno A, Businaro L, Gerardino A, Manic G, Ulas T, Schultze JL, Rusakiewicz S, Lucattelli M, Delaloge S, Vitale I, Vacchelli E, Ma Y, Baracco EE, Enot DP, Pietrocola F, Yang H, Adjemian S, Chaba K, Signore M, Lucarini V, Peschiaroli F, G?nther P, Kepp O, Stoll G, Lefebvre C, Mulot C, Castoldi F, Ladoire S, Apetoh L, Bravo-San Pedro JM, Delarasse C, Boige V, Ducreux M, Borg C, Andr? F, Schiavoni G, Laurent-Puig P, Mattei F, Zitvogel L, Kroemer G. Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1. Science. 2015 Nov 20; 350(6263):972-8. PMID: 26516201.
      Citations: 207     Fields:    Translation:HumansAnimalsCells
    156. Schultze JL. Reprogramming of macrophages--new opportunities for therapeutic targeting. Curr Opin Pharmacol. 2016 Feb; 26:10-5. PMID: 26426255.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    157. Labzin LI, Schmidt SV, Masters SL, Beyer M, Krebs W, Klee K, Stahl R, Schultze JL, Latz E, De Nardo D, L?tjohann D. ATF3 Is a Key Regulator of Macrophage IFN Responses. J Immunol. 2015 Nov 01; 195(9):4446-55. PMID: 26416280.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    158. Jung S, B?ttcher JP, Beyer M, Meissner F, Abdullah Z, Sander J, H?chst B, Eickhoff S, Rieckmann JC, Russo C, Bauer T, Flecken T, Giesen D, Engel D, Busch DH, Protzer U, Thimme R, Mann M, Kurts C, Schultze JL, Kastenm?ller W, Knolle PA. Functional classification of memory CD8(+) T cells by CX3CR1 expression. Nat Commun. 2015 Sep 25; 6:8306. PMID: 26404698; PMCID: PMC4667439.
      Citations: 146     Fields:    Translation:HumansAnimalsCells
    159. Schultze JL. Teaching 'big data' analysis to young immunologists. Nat Immunol. 2015 Sep; 16(9):902-5. PMID: 26287590.
      Citations: 7     Fields:    Translation:Humans
    160. Schultze JL, Schmieder A, Goerdt S. Macrophage activation in human diseases. Semin Immunol. 2015 Aug; 27(4):249-56. PMID: 26303100.
      Citations: 56     Fields:    Translation:HumansAnimals
    161. Mitschka S, Ulas T, Goller T, Schneider K, Egert A, Schorle H, Beyer M, Klee K, Xue J, Bassler K, Schultze JL, Kolanus W, Mertens J, Br?stle O, G?nther P. Co-existence of intact stemness and priming of neural differentiation programs in mES cells lacking Trim71. Sci Rep. 2015 Jun 09; 5:11126. PMID: 26057209; PMCID: PMC4460895.
      Citations: 24     Fields:    Translation:AnimalsCells
    162. Schultze JL. Transcriptional programming of human macrophages: on the way to systems immunology. J Mol Med (Berl). 2015 Jun; 93(6):589-97. PMID: 25877862.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    163. Schultze JL, Freeman T, Hume DA, Latz E. A transcriptional perspective on human macrophage biology. Semin Immunol. 2015 Feb; 27(1):44-50. PMID: 25843246.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    164. Sommer D, Peters AE, Wirtz T, Mai M, Ackermann J, Thabet Y, Weighardt H, Wunderlich FT, Degen J, Schultze JL, Beyer M, Schmidt J. Corrigendum: Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases. Nat Commun. 2015 Feb 20; 6:5927. PMID: 25698449.
      Citations:    Fields:    
    165. Schultze JL. Global transcriptional regulation in the immune system. Editorial. Semin Immunol. 2015 Feb; 27(1):1-3. PMID: 25926421.
      Citations:    Fields:    Translation:HumansAnimalsCells
    166. Friesenhagen J, Petersen B, Burgmann J, Faist E, Zedler S, Pirr S, Rohde C, von Kaisenberg CS, Ulas T, Schultze JL, Viemann D, Austermann J, Fassl SK, Ortkras T, Barczyk-Kahlert K, M?ller-Tidow C, von K?ckritz-Blickwede M, Floh? SB, Roth J, Vogl T. Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions. Cell Rep. 2014 Dec 24; 9(6):2112-23. PMID: 25497086.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    167. Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T. Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8. J Immunol. 2015 Jan 15; 194(2):575-83. PMID: 25505274.
      Citations: 33     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    168. Krebs W, Schmidt SV, Goren A, De Nardo D, Labzin L, Bovier A, Ulas T, Theis H, Kraut M, Latz E, Beyer M, Schultze JL. Optimization of transcription factor binding map accuracy utilizing knockout-mouse models. Nucleic Acids Res. 2014 Dec 01; 42(21):13051-60. PMID: 25378309; PMCID: PMC4245947.
      Citations: 12     Fields:    Translation:AnimalsCells
    169. Adam J, Vitale I, Goubar A, Fend L, Schultze JL, Lacroix-Triki M, Quidville V, Pusztai L, Poirier-Colame V, Delaloge S, Penault-Llorca F, Cyrta J, Dessoliers MC, Bianchi ME, Pittet M, Engblom C, Pfirschke C, Schreiber RD, Chow MT, Smyth MJ, Sistigu A, Yamazaki T, Vacchelli E, Chaba K, Enot DP, Baracco EE, Rem?dios C, Hannani D, Aymeric L, Ma Y, Niso-Santano M, Kepp O, T?ting T, Belardelli F, Bracci L, La Sorsa V, Ziccheddu G, Sestili P, Urbani F, Delorenzi M, Conforti R, Spano JP, Ladoire S, Arnould L, Eggermont A, Pr?ville X, Uz? G, Proietti E, Andr? F, Kroemer G, Zitvogel L. Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy. Nat Med. 2014 Nov; 20(11):1301-9. PMID: 25344738.
      Citations: 499     Fields:    Translation:HumansAnimalsCells
    170. Lundt R, Ternes S, Ulas T, Schultze JL, Bano D, Nicotera P, Zimmer A, Schm?le AC, Albayram ?, Alferink J. Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model. Neurobiol Aging. 2015 Feb; 36(2):710-9. PMID: 25443294.
      Citations: 33     Fields:    Translation:AnimalsCells
    171. Schanz O, Zaremba A, Hegenbarth S, Kurts C, Beyer M, Schultze JL, B?ttcher JP, Garbers C, Kastenm?ller W, Rose-John S, Knolle PA. IL-6 trans-signaling-dependent rapid development of cytotoxic CD8+ T cell function. Cell Rep. 2014 Sep 11; 8(5):1318-27. PMID: 25199826.
      Citations: 50     Fields:    Translation:AnimalsCells
    172. Schmidt SV, Schultze JL. New Insights into IDO Biology in Bacterial and Viral Infections. Front Immunol. 2014; 5:384. PMID: 25157255; PMCID: PMC4128074.
      Citations: 81     Fields:    
    173. Murray PJ, Allen JE, Biswas SK, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Fisher EA, Gilroy DW, Sica A, Wynn TA. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity. 2014 Jul 17; 41(1):14-20. PMID: 25035950; PMCID: PMC4123412.
      Citations: 2638     Fields:    Translation:HumansAnimalsCells
    174. Kummer MP, Terwel D, Schwartz S, Schultze JL, Weinshenker D, Heneka MT, Urban I, Hammerschmidt T, Martinez A, Eichele G, Witten A, Figura S, Stoll M, Pape HC. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. J Neurosci. 2014 Jun 25; 34(26):8845-54. PMID: 24966384; PMCID: PMC4147626.
      Citations: 36     Fields:    Translation:AnimalsCells
    175. Schultze JL. Precision attack on calcineurin in macrophages: a new anti-inflammatory weapon. EMBO J. 2014 May 16; 33(10):1087-8. PMID: 24674968; PMCID: PMC4193915.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    176. Xue J, Schmidt SV, Sander J, Draffehn A, Krebs W, Quester I, De Nardo D, Gohel TD, Emde M, Schmidleithner L, Ganesan H, Nino-Castro A, Mallmann MR, Labzin L, Theis H, Kraut M, Beyer M, Latz E, Freeman TC, Ulas T, Schultze JL. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity. 2014 Feb 20; 40(2):274-88. PMID: 24530056; PMCID: PMC3991396.
      Citations: 995     Fields:    Translation:HumansAnimalsCells
    177. Sommer D, Peters A, Wirtz T, Mai M, Ackermann J, Thabet Y, Weighardt H, Wunderlich FT, Degen J, Schultze JL, Beyer M, Schmidt J. Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases. Nat Commun. 2014; 5:3045. PMID: 24413636.
      Citations: 20     Fields:    Translation:AnimalsCells
    178. Steiner N, Lukacs-Kornek V, Degrandi D, Dresing P, Alferink J, Lang R, Pfeffer K, Beyer M, Weighardt H, Kurts C, Ulas T, Schultze JL, Globisch T, F?lle L, F?rster I. Cytokine-dependent regulation of dendritic cell differentiation in the splenic microenvironment. Eur J Immunol. 2014 Feb; 44(2):500-10. PMID: 24136200.
      Citations: 11     Fields:    Translation:AnimalsCells
    179. De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Wright SD, Schultze JL, Latz E, R?cken M, L?tjohann D. High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nat Immunol. 2014 Feb; 15(2):152-60. PMID: 24317040; PMCID: PMC4009731.
      Citations: 183     Fields:    Translation:HumansAnimalsCells
    180. Mattarollo SR, Adjemian S, Yang H, Aymeric L, Hannani D, Duret H, Teng MW, Kepp O, Wang Y, Sistigu A, Schultze JL, Stoll G, Galluzzi L, Zitvogel L, Smyth MJ, Kroemer G, Ma Y, Portela Catani JP. CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy. Cancer Res. 2014 Jan 15; 74(2):436-45. PMID: 24302580.
      Citations: 69     Fields:    Translation:AnimalsCells
    181. Lickfett L, Bosen F, Dobrowolski R, Draffehn AM, Fregeac J, Schultze JL, Bukauskas FF, Schrickel JW, Willecke K, L?bkemeier I, Andri? R, St?ckigt F. The Connexin40A96S mutation from a patient with atrial fibrillation causes decreased atrial conduction velocities and sustained episodes of induced atrial fibrillation in mice. J Mol Cell Cardiol. 2013 Dec; 65:19-32. PMID: 24060583.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    182. Schultze J. [Prof. Dr. med. Dr. rer. nat. Bernhard Kimmig conferred emeritus status]. Strahlenther Onkol. 2013 Sep; 189(9):803. PMID: 23896632.
      Citations:    Fields:    Translation:Humans
    183. Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze JL, Roodbergen M, Hoeijmakers JH, Benzing T, Kurschat CE, Schumacher B, N?rnberg P, Doll? ME, M?ller RU. Transcriptional profiling reveals progeroid Ercc1(-/?) mice as a model system for glomerular aging. BMC Genomics. 2013 Aug 16; 14:559. PMID: 23947592; PMCID: PMC3751413.
      Citations: 8     Fields:    Translation:AnimalsCells
    184. Abdullah Z, Popov A, Thabet Y, Beyer M, Knolle P, Domann E, Chakraborty T, Schmidt SV, Schultze JL, Ni?o-Castro A. The IDO1-induced kynurenines play a major role in the antimicrobial effect of human myeloid cells against Listeria monocytogenes. Innate Immun. 2014 May; 20(4):401-11. PMID: 23940074.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    185. Beutner C, Linnartz-Gerlach B, Schmidt SV, Beyer M, Mallmann MR, Staratschek-Jox A, Schultze JL, Neumann H. Unique transcriptome signature of mouse microglia. Glia. 2013 Sep; 61(9):1429-42. PMID: 23832717.
      Citations: 63     Fields:    Translation:AnimalsCells
    186. Langhans B, Louis M, Nischalke HD, Staratschek-Jox A, Odenthal M, Manekeller S, Schepke M, Fischer HP, Schultze JL, Spengler U, Kr?mer B, H?neburg R, Kalff J. Intrahepatic IL-8 producing Foxp3?CD4? regulatory T cells and fibrogenesis in chronic hepatitis C. J Hepatol. 2013 Aug; 59(2):229-35. PMID: 23624000.
      Citations: 32     Fields:    Translation:HumansCells
    187. Schanz O, Wohlleber D, Abdullah Z, Debey-Pascher S, Staratschek-Jox A, Hegenbarth S, Grell J, Limmer A, Atreya I, Neurath MF, Busch DH, Schmitt E, van Endert P, Kolanus W, Kurts C, Schultze JL, Diehl L, Knolle PA, B?ttcher JP, H?chst B. Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity. Cell Rep. 2013 Mar 28; 3(3):779-95. PMID: 23499443.
      Citations: 37     Fields:    Translation:AnimalsCells
    188. Jux B, Staratschek-Jox A, Penninger JM, Schultze JL, Kolanus W. Vav1 regulates MHCII expression in murine resting and activated B cells. Int Immunol. 2013 May; 25(5):307-17. PMID: 23391492.
      Citations: 3     Fields:    Translation:AnimalsCells
    189. Herzfeld T, Nolte D, Grznarova M, Hofmann A, Schultze JL, M?ller U. X-linked dystonia parkinsonism syndrome (XDP, lubag): disease-specific sequence change DSC3 in TAF1/DYT3 affects genes in vesicular transport and dopamine metabolism. Hum Mol Genet. 2013 Mar 01; 22(5):941-51. PMID: 23184149.
      Citations: 18     Fields:    Translation:HumansCells
    190. Roth W, Kumar V, Beer HD, Richter M, Wohlenberg C, Reuter U, Staratschek-Jox A, Hofmann A, Kreusch F, Schultze JL, Vogl T, Roth J, Reichelt J, Hausser I, Magin TM, Thiering S. Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18. J Cell Sci. 2012 Nov 15; 125(Pt 22):5269-79. PMID: 23132931.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    191. Beyer M, Mallmann MR, Xue J, Staratschek-Jox A, Vorholt D, Krebs W, Sommer D, Sander J, Mertens C, Nino-Castro A, Schmidt SV, Schultze JL. High-resolution transcriptome of human macrophages. PLoS One. 2012; 7(9):e45466. PMID: 23029029; PMCID: PMC3448669.
      Citations: 148     Fields:    Translation:HumansCells
    192. Schmidt SV, Nino-Castro AC, Schultze JL. Regulatory dendritic cells: there is more than just immune activation. Front Immunol. 2012; 3:274. PMID: 22969767; PMCID: PMC3432880.
      Citations: 96     Fields:    
    193. Hammerschmidt T, Kummer MP, Terwel D, Martinez A, Gorji A, Pape HC, Rommelfanger KS, Schroeder JP, Stoll M, Schultze J, Weinshenker D, Heneka MT. Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice. Biol Psychiatry. 2013 Mar 01; 73(5):454-63. PMID: 22883210; PMCID: PMC4712953.
      Citations: 46     Fields:    Translation:AnimalsCells
    194. Geiger S, Nino-Castro A, Muraliv E, Gaidt M, Schildberg FA, Riethausen K, Flossdorf J, Krebs W, Chakraborty T, Kurts C, Schultze JL, Knolle PA, Klotz L, Abdullah Z, B?ttcher JP. Lack of PPAR? in myeloid cells confers resistance to Listeria monocytogenes infection. PLoS One. 2012; 7(5):e37349. PMID: 22629382; PMCID: PMC3357414.
      Citations: 17     Fields:    Translation:AnimalsCells
    195. Terme M, Ullrich E, Aymeric L, Meinhardt K, Viaud S, Ryffel B, Yagita H, Chen L, Kaplanski G, Kato M, Schultze JL, Tartour E, Kroemer G, Degli-Esposti M, Chaput N, Zitvogel L, Coudert JD, Desbois M, Ghiringhelli F, M?cheri S, Pr?vost-Blondel A. Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells. Cancer Res. 2012 Jun 01; 72(11):2757-67. PMID: 22427351.
      Citations: 50     Fields:    Translation:AnimalsCells
    196. Beyer M, Schumak B, Weihrauch MR, Andres B, Giese T, Endl E, Knolle PA, Classen S, Limmer A, Schultze JL. In vivo expansion of na?ve CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration. PLoS One. 2012; 7(1):e30422. PMID: 22276195; PMCID: PMC3262821.
      Citations: 13     Fields:    Translation:HumansCells
    197. Ihler F, Vetter EV, Pan J, Kammerer R, Debey-Pascher S, Schultze JL, Zimmermann W, Enders G. Expression of a neuroendocrine gene signature in gastric tumor cells from CEA 424-SV40 large T antigen-transgenic mice depends on SV40 large T antigen. PLoS One. 2012; 7(1):e29846. PMID: 22253802; PMCID: PMC3258231.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    198. Schwandt T, Schumak B, Gielen GH, Schmidbauer P, Klocke K, Staratschek-Jox A, van Rooijen N, Kraal G, Ludwig-Portugall I, Franken L, Wehner S, Weber O, Kirschning C, Coch C, Kalinke U, Kurts C, Zawatzky R, Holzmann B, Layland L, Schultze JL, Burgdorf S, den Haan JM, Knolle PA, Limmer A, J?ngerkes F, Kalff JC, Wenzel J. Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis. EMBO J. 2012 Jan 04; 31(1):201-13. PMID: 22036947; PMCID: PMC3252580.
      Citations: 24     Fields:    Translation:AnimalsCells
    199. Beyer M, Classen S, Endl E, Kochanek M, Weihrauch MR, Debey-Pascher S, Knolle PA, Schultze JL. Comparative approach to define increased regulatory T cells in different cancer subtypes by combined assessment of CD127 and FOXP3. Clin Dev Immunol. 2011; 2011:734036. PMID: 21904560; PMCID: PMC3166761.
      Citations: 20     Fields:    Translation:HumansCells
    200. Beyer M, Thabet Y, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, Endl E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, Schultze JL, M?ller RU, Sch?nfeld EA, B?ttcher J, Mayer G. Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol. 2011 Aug 14; 12(9):898-907. PMID: 21841785; PMCID: PMC3669688.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    201. McInnes N, Sadlon TJ, Brown CY, Pederson S, Beyer M, Schultze JL, McColl S, Goodall GJ, Barry SC. FOXP3 and FOXP3-regulated microRNAs suppress SATB1 in breast cancer cells. Oncogene. 2012 Feb 23; 31(8):1045-54. PMID: 21743493.
      Citations: 47     Fields:    Translation:HumansCells
    202. Debey-Pascher S, Hofmann A, Kreusch F, Schuler G, Schuler-Thurner B, Schultze JL, Staratschek-Jox A. RNA-stabilized whole blood samples but not peripheral blood mononuclear cells can be stored for prolonged time periods prior to transcriptome analysis. J Mol Diagn. 2011 Jul; 13(4):452-60. PMID: 21704280; PMCID: PMC3123794.
      Citations: 15     Fields:    Translation:HumansCells
    203. Ullrich E, Aymeric L, Meinhardt K, Delahaye N, Viaud S, Ryffel B, Yagita H, Kaplanski G, Kato M, Schultze JL, Tartour E, Kroemer G, Chaput N, Zitvogel L, Terme M, Desbois M, Pr?vost-Blondel A. IL-18 induces PD-1-dependent immunosuppression in cancer. Cancer Res. 2011 Aug 15; 71(16):5393-9. PMID: 21724589.
      Citations: 161     Fields:    Translation:AnimalsCells
    204. Zander T, Hofmann A, Staratschek-Jox A, Classen S, Debey-Pascher S, Maisel D, Hahn M, Beyer M, Thomas RK, Gathof B, Mauch C, Delank KS, Engel-Riedel W, Wichmann HE, Stoelben E, Schultze JL, Ans?n S, Wolf J. Blood-based gene expression signatures in non-small cell lung cancer. Clin Cancer Res. 2011 May 15; 17(10):3360-7. PMID: 21558400.
      Citations: 39     Fields:    Translation:HumansCells
    205. von Bubnoff D, Scheler M, Wilms H, Schultze J, Popov A, Racz P, Bieber T, Wickenhauser C, Wenzel J, von Bubnoff N, H?cker G. Indoleamine 2,3-dioxygenase-expressing myeloid dendritic cells and macrophages in infectious and noninfectious cutaneous granulomas. J Am Acad Dermatol. 2011 Oct; 65(4):819-832. PMID: 21501890.
      Citations: 8     Fields:    Translation:HumansCells
    206. Beyer M, Schultze JL. Plasticity of T(reg) cells: is reprogramming of T(reg) cells possible in the presence of FOXP3? Int Immunopharmacol. 2011 May; 11(5):555-60. PMID: 21115121.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    207. Gupta MK, Illich DJ, Gaarz A, Matzkies M, Nguemo F, Pfannkuche K, Liang H, Classen S, Reppel M, Schultze JL, Saric T, Hescheler J. Global transcriptional profiles of beating clusters derived from human induced pluripotent stem cells and embryonic stem cells are highly similar. BMC Dev Biol. 2010 Sep 15; 10:98. PMID: 20843318; PMCID: PMC2946283.
      Citations: 45     Fields:    Translation:HumansCells
    208. Mallmann MR, Staratschek-Jox A, Rudlowski C, Braun M, Gaarz A, Wolfgarten M, Kuhn W, Schultze JL. Prediction and prognosis: impact of gene expression profiling in personalized treatment of breast cancer patients. EPMA J. 2010 Sep; 1(3):421-37. PMID: 23199086; PMCID: PMC3405335.
      Citations: 3     
    209. Kern M, Popov A, Kurts C, Schultze JL, Knolle PA. Taking off the brakes: T cell immunity in the liver. Trends Immunol. 2010 Aug; 31(8):311-7. PMID: 20619740.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    210. Gaarz A, Debey-Pascher S, Classen S, Eggle D, Gathof B, Chen J, Fan JB, Voss T, Schultze JL, Staratschek-Jox A. Bead array-based microrna expression profiling of peripheral blood and the impact of different RNA isolation approaches. J Mol Diagn. 2010 May; 12(3):335-44. PMID: 20228267; PMCID: PMC2860470.
      Citations: 13     Fields:    Translation:HumansCells
    211. Classen S, Muth C, Debey-Pascher S, Eggle D, Beyer M, Mallmann MR, Rudlowski C, Zander T, Kuhn W, Lahn M, Schultze JL, Staratschek-Jox A, P?lcher M. Application of T cell-based transcriptomics to identify three candidate biomarkers for monitoring anti-TGFbetaR therapy. Pharmacogenet Genomics. 2010 Mar; 20(3):147-56. PMID: 20084050.
      Citations: 7     Fields:    Translation:HumansCells
    212. Staratschek-Jox A, Schultze JL. Re-overcoming barriers in translating biomarkers to clinical practice. Expert Opin Med Diagn. 2010 Mar; 4(2):103-12. PMID: 23484444.
      Citations: 1     Fields:    
    213. Becker T, Loch G, Beyer M, Zinke I, Aschenbrenner AC, Carrera P, Inhester T, Schultze JL, Hoch M. FOXO-dependent regulation of innate immune homeostasis. Nature. 2010 Jan 21; 463(7279):369-73. PMID: 20090753.
      Citations: 156     Fields:    Translation:HumansAnimalsCells
    214. Kondo E, Maecker B, Draube A, Klein-Gonzalez N, Shimabukuro-Vornhagen A, Schultze JL, von Bergwelt-Baildon MS. The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells. Int J Cancer. 2009 Nov 15; 125(10):2474-8. PMID: 19681121.
      Citations: 1     Fields:    Translation:HumansCells
    215. Klotz L, Burgdorf S, Dani I, Saijo K, Flossdorf J, Hucke S, Alferink J, Nowak N, Novak N, Beyer M, Mayer G, Langhans B, Klockgether T, Waisman A, Eberl G, Schultze J, Famulok M, Kolanus W, Glass C, Kurts C, Knolle PA. The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J Exp Med. 2009 Sep 28; 206(10):2079-89. PMID: 19737866; PMCID: PMC2757877.
      Citations: 163     Fields:    Translation:HumansAnimalsCells
    216. Kern M, Popov A, Scholz K, Schumak B, Djandji D, Limmer A, Eggle D, Sacher T, Zawatzky R, Holtappels R, Reddehase MJ, Hartmann G, Debey-Pascher S, Diehl L, Kalinke U, Koszinowski U, Schultze J, Knolle PA. Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity. Gastroenterology. 2010 Jan; 138(1):336-46. PMID: 19737567.
      Citations: 37     Fields:    Translation:AnimalsCells
    217. Schurich A, Burgdorf S, Penzler P, Hegenbarth S, Kern M, Dolf A, Endl E, Schultze J, Wiertz E, Stabenow D, Kurts C, Knolle P, B?ttcher JP. Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells. Hepatology. 2009 Sep; 50(3):909-19. PMID: 19610048.
      Citations: 35     Fields:    Translation:AnimalsCells
    218. Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM, Krause G. miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia. Blood. 2009 Oct 08; 114(15):3255-64. PMID: 19692702; PMCID: PMC2925729.
      Citations: 67     Fields:    Translation:HumansCells
    219. Terme M, Ullrich E, Bonmort M, Jacquet A, Schultze JL, Kroemer G, Leclerc C, Chaput N, Zitvogel L, Mignot G, Minard-Colin V. The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells. Cancer Res. 2009 Aug 15; 69(16):6590-7. PMID: 19679551.
      Citations: 16     Fields:    Translation:AnimalsCells
    220. Eggle D, Debey-Pascher S, Beyer M, Schultze JL. The development of a comparison approach for Illumina bead chips unravels unexpected challenges applying newest generation microarrays. BMC Bioinformatics. 2009 Jun 18; 10:186. PMID: 19538710; PMCID: PMC2711080.
      Citations: 3     Fields:    Translation:Humans
    221. Klotz L, Hucke S, Thimm D, Classen S, Gaarz A, Schultze J, Edenhofer F, Kurts C, Klockgether T, Limmer A, Knolle P, Burgdorf S. Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1. J Immunol. 2009 Jul 01; 183(1):129-36. PMID: 19535643.
      Citations: 20     Fields:    Translation:AnimalsCells
    222. Beyer M, Karbach J, Mallmann MR, Zander T, Eggle D, Classen S, Debey-Pascher S, Famulok M, Schultze JL, J?ger E. Cancer vaccine enhanced, non-tumor-reactive CD8(+) T cells exhibit a distinct molecular program associated with "division arrest anergy". Cancer Res. 2009 May 15; 69(10):4346-54. PMID: 19435912.
      Citations: 6     Fields:    Translation:HumansCells
    223. Staratschek-Jox A, Classen S, Gaarz A, Debey-Pascher S, Schultze JL. Blood-based transcriptomics: leukemias and beyond. Expert Rev Mol Diagn. 2009 Apr; 9(3):271-80. PMID: 19379085.
      Citations: 10     Fields:    Translation:Humans
    224. Siebolts U, Breuhahn K, Hennecke A, Schultze JL, Wickenhauser C. Imbalance of DNA-dependent protein kinase subunits in polycythemia vera peripheral blood stem cells. Int J Cancer. 2009 Feb 01; 124(3):600-7. PMID: 19004005.
      Citations:    Fields:    Translation:HumansCells
    225. Kondo E, Gryschok L, Schultze JL, von Bergwelt-Baildon MS. Using CD40-activated B cells to efficiently identify epitopes of tumor antigens. J Immunother. 2009 Feb-Mar; 32(2):157-60. PMID: 19238014.
      Citations: 1     Fields:    Translation:HumansCells
    226. Debey-Pascher S, Eggle D, Schultze JL. RNA stabilization of peripheral blood and profiling by bead chip analysis. Methods Mol Biol. 2009; 496:175-210. PMID: 18839112.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    227. Beyer M, Schultze JL. Regulatory T cells: major players in the tumor microenvironment. Curr Pharm Des. 2009; 15(16):1879-92. PMID: 19519430.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    228. Kondo E, Maecker B, Weihrauch MR, Wickenhauser C, Zeng W, Nadler LM, Schultze JL, von Bergwelt-Baildon MS. Cyclin D1-specific cytotoxic T lymphocytes are present in the repertoire of cancer patients: implications for cancer immunotherapy. Clin Cancer Res. 2008 Oct 15; 14(20):6574-9. PMID: 18927298.
      Citations: 7     Fields:    Translation:HumansCells
    229. Popov A, Driesen J, Abdullah Z, Wickenhauser C, Beyer M, Debey-Pascher S, Saric T, Kummer S, Takikawa O, Domann E, Chakraborty T, Schultze JL, Kr?nke M, Uterm?hlen O. Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms. J Immunol. 2008 Oct 01; 181(7):4976-88. PMID: 18802101.
      Citations: 16     Fields:    Translation:HumansCells
    230. Classen S, Staratschek-Jox A, Schultze JL. Use of genome-wide high-throughput technologies in biomarker development. Biomark Med. 2008 Oct; 2(5):509-24. PMID: 20477427.
      Citations: 1     Fields:    
    231. Driesen J, Popov A, Schultze JL. CD25 as an immune regulatory molecule expressed on myeloid dendritic cells. Immunobiology. 2008; 213(9-10):849-58. PMID: 18926299.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    232. Guenther A, Eickelberg O, Preissner KT, Chambers R, Laurent G, Wells A, Crestani B, Vancheri C, Bonniaud P, Camus P, Schmitz G, Klepetko W, Schultze J, Vossmeyer D, Stumpf P. International registry for idiopathic pulmonary fibrosis. Thorax. 2008 Sep; 63(9):841; author reply 841. PMID: 18728209.
      Citations: 3     Fields:    Translation:Humans
    233. von Bergwelt-Baildon M, Kandic M, Weskott M, Klamp W, Rosler J, Schultze JL, Weihrauch MR. T cell responses to hepatitis B surface antigen are detectable in non-vaccinated individuals. World J Gastroenterol. 2008 Apr 28; 14(16):2529-33. PMID: 18442200; PMCID: PMC2708364.
      Citations: 6     Fields:    Translation:HumansCells
    234. Beyer M, Schultze JL. Immunoregulatory T cells: role and potential as a target in malignancy. Curr Oncol Rep. 2008 Mar; 10(2):130-6. PMID: 18377826.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    235. Pallasch CP, Schwamb J, Schulz A, Debey S, Kofler D, Schultze JL, Hallek M, Ultsch A, Wendtner CM, K?nigs S. Targeting lipid metabolism by the lipoprotein lipase inhibitor orlistat results in apoptosis of B-cell chronic lymphocytic leukemia cells. Leukemia. 2008 Mar; 22(3):585-92. PMID: 18079738.
      Citations: 47     Fields:    Translation:HumansCells
    236. Gnjatic S, Maeurer M, Old LJ, Karbach J, Pauligk C, Bender A, Schultze JL, Nadler K, Wahle C, Knuth A, J?ger E. Tumor-reactive CD8+ T-cell clones in patients after NY-ESO-1 peptide vaccination. Int J Cancer. 2007 Nov 01; 121(9):2042-2048. PMID: 17640060.
      Citations: 5     Fields:    Translation:HumansCells
    237. Popov A, Schultze JL. IDO-expressing regulatory dendritic cells in cancer and chronic infection. J Mol Med (Berl). 2008 Feb; 86(2):145-60. PMID: 17876564.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    238. Rebholz B, Haase I, Eckelt B, Paxian S, Flaig MJ, Ghoreschi K, Nedospasov SA, Mailhammer R, Debey-Pascher S, Schultze JL, Huss R, Stratis A, Ruzicka T, Pfeffer K, Schmid RM, Rupec RA, Weindl G, F?rster I, R?cken M. Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin. Immunity. 2007 Aug; 27(2):296-307. PMID: 17692539.
      Citations: 58     Fields:    Translation:AnimalsCells
    239. Chemnitz JM, Eggle D, Driesen J, Classen S, Riley JL, Debey-Pascher S, Beyer M, Popov A, Zander T, Schultze JL. RNA fingerprints provide direct evidence for the inhibitory role of TGFbeta and PD-1 on CD4+ T cells in Hodgkin lymphoma. Blood. 2007 Nov 01; 110(9):3226-33. PMID: 17644739.
      Citations: 30     Fields:    Translation:HumansCells
    240. Beyer M, Schultze JL. CD4+CD25highFOXP3+ regulatory T cells in peripheral blood are primarily of effector memory phenotype. J Clin Oncol. 2007 Jun 20; 25(18):2628-30; author reply 2630-2. PMID: 17577047.
      Citations: 9     Fields:    Translation:HumansCells
    241. Classen S, Zander T, Eggle D, Chemnitz JM, Brors B, Popov A, Beyer M, Eils R, Debey S, Schultze JL, B?chmann I. Human resting CD4+ T cells are constitutively inhibited by TGF beta under steady-state conditions. J Immunol. 2007 Jun 01; 178(11):6931-40. PMID: 17513742.
      Citations: 11     Fields:    Translation:HumansCells
    242. Draube A, Beyer M, Schumer S, Thomas RK, von Tresckow B, Koslowsky TC, Krieglstein CF, Schultze JL, Wolf J. Efficient activation of autologous tumor-specific T cells: a simple coculture technique of autologous dendritic cells compared to established cell fusion strategies in primary human colorectal carcinoma. J Immunother. 2007 May-Jun; 30(4):359-69. PMID: 17457211.
      Citations: 4     Fields:    Translation:HumansCells
    243. Jensen M, Klehr M, Vogel A, Schmitz S, Tawadros S, Fischer T, Schultze JL, Berthold F, M?hlenhoff M, Pl?ck A, Schom?cker K. One step generation of fully chimeric antibodies using Cgamma1- and Ckappa mutant mice. J Immunother. 2007 Apr; 30(3):338-49. PMID: 17414325.
      Citations:    Fields:    Translation:HumansAnimalsCells
    244. Schultze JL, Eggle D. IlluminaGUI: graphical user interface for analyzing gene expression data generated on the Illumina platform. Bioinformatics. 2007 Jun 01; 23(11):1431-3. PMID: 17384020.
      Citations: 7     Fields:    
    245. Popov A, Abdullah Z, Wickenhauser C, Saric T, Driesen J, Hanisch FG, Domann E, Raven EL, Dehus O, Hermann C, Eggle D, Debey S, Chakraborty T, Schultze JL, Kr?nke M, Uterm?hlen O. Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection. J Clin Invest. 2006 Dec; 116(12):3160-70. PMID: 17111046; PMCID: PMC1636691.
      Citations: 76     Fields:    Translation:HumansCells
    246. Schmitz R, Thomas RK, Harttrampf AC, Wickenhauser C, Schultze JL, Hansmann ML, Wolf J, K?ppers R. The major subtypes of human B-cell lymphomas lack mutations in BCL-2 family member BAD. Int J Cancer. 2006 Oct 01; 119(7):1738-40. PMID: 16646081.
      Citations: 1     Fields:    Translation:HumansCells
    247. Schultze JL. [Requirements for the development of molecularly defined targeted therapy in oncology]. Med Klin (Munich). 2006 Aug 15; 101(8):617-23. PMID: 16896568.
      Citations:    Fields:    Translation:Humans
    248. Beyer M, Schultze JL. Regulatory T cells in cancer. Blood. 2006 Aug 01; 108(3):804-11. PMID: 16861339.
      Citations: 273     Fields:    Translation:HumansAnimalsCells
    249. Fiore F, Von Bergwelt-Baildon MS, Drebber U, Beyer M, Popov A, Manzke O, Wickenhauser C, Baldus SE, Schultze JL. Dendritic cells are significantly reduced in non-Hodgkin's lymphoma and express less CCR7 and CD62L. Leuk Lymphoma. 2006 Apr; 47(4):613-22. PMID: 16690519.
      Citations: 10     Fields:    Translation:HumansCells
    250. Zander T, Faigle U, Schultze JL, Schrader R, Kaderali L, Wolf J. CASPAR: a hierarchical bayesian approach to predict survival times in cancer from gene expression data. Bioinformatics. 2006 Jun 15; 22(12):1495-502. PMID: 16554338.
      Citations: 11     Fields:    Translation:HumansCells
    251. Bartsch M, Gobbato E, Bednarek P, Debey S, Schultze JL, Bautor J, Parker JE. Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Plant Cell. 2006 Apr; 18(4):1038-51. PMID: 16531493; PMCID: PMC1425861.
      Citations: 228     Fields:    Translation:AnimalsCells
    252. von Bergwelt-Baildon MS, Popov A, Saric T, Chemnitz J, Classen S, Stoffel MS, Fiore F, Roth U, Beyer M, Debey S, Wickenhauser C, Hanisch FG, Schultze JL. CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition. Blood. 2006 Jul 01; 108(1):228-37. PMID: 16522817.
      Citations: 90     Fields:    Translation:HumansCells
    253. Chemnitz JM, Driesen J, Classen S, Riley JL, Debey S, Beyer M, Popov A, Zander T, Schultze JL. Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma. Cancer Res. 2006 Jan 15; 66(2):1114-22. PMID: 16424048.
      Citations: 48     Fields:    Translation:HumansCells
    254. Beyer M, Kochanek M, Giese T, Endl E, Weihrauch MR, Knolle PA, Classen S, Schultze JL. In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma. Blood. 2006 May 15; 107(10):3940-9. PMID: 16410445.
      Citations: 117     Fields:    Translation:HumansCells
    255. Debey S, Zander T, Brors B, Popov A, Eils R, Schultze JL. A highly standardized, robust, and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials. Genomics. 2006 May; 87(5):653-64. PMID: 16387473.
      Citations: 30     Fields:    Translation:HumansCells
    256. Shimabukuro-Vornhagen A, Popov A, Klein-Gonzalez N, Fiore F, Debey S, Draube A, Maecker B, Menezes I, Nadler LM, Schultze JL, von Bergwelt-Baildon M. CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants. Blood. 2006 Apr 01; 107(7):2786-9. PMID: 16357329; PMCID: PMC1895368.
      Citations: 27     Fields:    Translation:HumansCells
    257. Thomas RK, Sos ML, Zander T, Mani O, Popov A, Berenbrinker D, Smola-Hess S, Schultze JL, Wolf J. Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies. Clin Cancer Res. 2005 Nov 15; 11(22):8186-94. PMID: 16299251.
      Citations: 3     Fields:    Translation:HumansCells
    258. Maecker B, von Bergwelt-Baildon MS, Anderson KS, Vonderheide RH, Anderson KC, Nadler LM, Schultze JL. Rare naturally occurring immune responses to three epitopes from the widely expressed tumour antigens hTERT and CYP1B1 in multiple myeloma patients. Clin Exp Immunol. 2005 Sep; 141(3):558-62. PMID: 16045747; PMCID: PMC1809449.
      Citations: 9     Fields:    Translation:HumansCells
    259. Weihrauch MR, Manzke O, Beyer M, Haverkamp H, Diehl V, Bohlen H, Wolf J, Schultze JL. Elevated serum levels of CC thymus and activation-related chemokine (TARC) in primary Hodgkin's disease: potential for a prognostic factor. Cancer Res. 2005 Jul 01; 65(13):5516-9. PMID: 15994922.
      Citations: 30     Fields:    Translation:Humans
    260. Maecker B, von Bergwelt-Baildon MS, Sherr DH, Nadler LM, Schultze JL. Identification of a new HLA-A*0201-restricted cryptic epitope from CYP1B1. Int J Cancer. 2005 Jun 10; 115(2):333-6. PMID: 15688394.
      Citations: 3     Fields:    Translation:HumansCells
    261. Thomas RK, Schmitz R, Harttrampf AC, Abdil-Hadi A, Wickenhauser C, Distler V, Hansmann ML, Schultze JL, Wolf J, K?ppers R. Apoptosis-resistant phenotype of classical Hodgkin's lymphoma is not mediated by somatic mutations within genes encoding members of the death-inducing signaling complex (DISC). Leukemia. 2005 Jun; 19(6):1079-82. PMID: 15815717.
      Citations:    Fields:    Translation:HumansCells
    262. Beyer M, Kochanek M, Darabi K, Popov A, Jensen M, Endl E, Knolle PA, Thomas RK, von Bergwelt-Baildon M, Debey S, Hallek M, Schultze JL. Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine. Blood. 2005 Sep 15; 106(6):2018-25. PMID: 15914560.
      Citations: 170     Fields:    Translation:HumansCells
    263. Both M, Schultze J, Reuter M, Bewig B, Hubner R, Bobis I, Noth R, Heller M, Biederer J. Fast T1- and T2-weighted pulmonary MR-imaging in patients with bronchial carcinoma. Eur J Radiol. 2005 Mar; 53(3):478-88. PMID: 15741023.
      Citations: 10     Fields:    Translation:Humans
    264. Schultze JL, Grabbe S, von Bergwelt-Baildon MS. DCs and CD40-activated B cells: current and future avenues to cellular cancer immunotherapy. Trends Immunol. 2004 Dec; 25(12):659-64. PMID: 15530836.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    265. von Bergwelt-Baildon M, Maecker B, Schultze J, Gribben JG. CD40 activation: potential for specific immunotherapy in B-CLL. Ann Oncol. 2004 Jun; 15(6):853-7. PMID: 15151939.
      Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
    266. von Bergwelt-Baildon M, Schultze JL, Maecker B, Menezes I, Nadler LM. Correspondence re R. Lapointe et al., CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells. Cancer Res 2003;63:2836-43. Cancer Res. 2004 Jun 01; 64(11):4055-6; author reply 4056-7. PMID: 15173021.
      Citations: 14     Fields:    Translation:HumansCells
    267. Wendt TG, Martin T, Baltas D, Kurek R, Tunn UW, Zamboglou N, Lukas P, Cavanaugh SX, Kupelian P, Reddy C, Pollock B, Fuss M, Roeddiger S, Dannenberg T, Rogge B, Koltze H, Munnes M, Wirtz R, Sauer R, Ott O, Strnad V, Warszawski A, Baumann R, Madry-Gevecke B, Karstens JH, Bamberg M, Banz N, Salz H, Schwedas M, van Kampen M, Schild S, Ikezaki K, Sieber R, Laufs S, Zeller W, Fritz P, Bach P, Wahlers B, Kraus HJ, Hahn SM, Schreiber FS, Rustgi AK, McKenna WG, Bernhard EJ, Willner J, Li M, Gong P, Trinh T, Huber PE, Price R, Ang KK, Maier-Hauff K, Seebass M, Dani A, Varkonyi A, Osvath M, Szasz A, Hayen J, Grundtke H, Dilcher C, Chan RC, Mintz GS, Kotani JI, Shah VM, Canos DA, Weissman NJ, Waksman R, Wolfram R, Timmermann B, Lomax A, Goitein G, Bernhard S, Gerstein J, Polivka B, Bremer M, Mathias K, Steinvorth S, van Oorschot B, Kisters K, Al-Nawas B, Klein MO, Ludwig C, Meyer A, Milicic B, Acimovic L, Milisavljevic S, Radosavljevic-Asic G, Oppenkowski R, Guntrum F, Malaimare L, Raub M, Averbeck T, Edler L, Molina H, Schlegel W, Kleinert G, Hamm K, Nill S, Rhein B, Merz T, Sommer B, Mencl A, Ghilescu V, Gorbatov T, Schmitz H, Spahn U, Prott PJ, Voith C, Zuna I, John E, Lochhas G, Houf M, Lorenz D, Link KH, Prott FJ, Romano M, Naszaly A, Patonay P, Block T, Czempiel H, Knutzen B, Souchon R, Ramm U, Licner J, Rudolf F, Moog J, Rahl CG, Stieltjes B, Salter BJ, Haferanke J, Panke JE, Hoelscher T, Georgi JC, Plathow C, Zieher H, Kiessling F, Peschke P, Kauczor HU, Stoffregen C, Lipson K, Achanta P, Thompson K, Martinez JL, Pakala R, Pinnow E, Hellinga D, O'Tio F, Oettel A, Schaal C, Reinhold M, Strasssmann G, Braun I, Vacha P, Richter D, Osterham T, Wolf P, Miemietz M, Lazaridis EA, Forthuber B, Horstmann G, Schoepgens H, Van Eck A, Bundschuh O, Van Oosterhut A, Xydis K, Theodorou K, Kappas C, Zurheide J, Ley S, Fink C, Puderbach M, Jung K, Rolf E, Damrau M, Maurer U, Maurer G, Lang K, Zumbe J, Schiebe M, Pinkert U, Herbst M, Dietl B, Schroeder F, Sigingan-Tek G, Feierabend R, Justus B, Huston AL, Seaborn R, Rai P, Rha SW, Sakas G, Wesarg S, Zogal P, Schwald B, Seibert H, Schoenekaes K, Isik D, Gademann G, Pambor C, Grie?bach I, von Specht H, R?ddiger S, Eich HT, Staar S, Gossmann A, Hansemann K, Semrau R, Skripnitchenko R, Diehl V, M?ller RP, Sehlen S, Willich N, R?hl U, D?hmke E, Engel K, Tabbert E, Bolck M, Knaack S, Annweiler H, Krempien R, Hoppe H, Harms W, Daeuber S, Schorr O, Treiber M, Debus J, Alber M, Paulsen F, Birkner M, Bakai A, Belka C, Budach W, Grosser KH, Kramer R, Kober B, Reinert M, Schneider P, Hertel A, Feldmann H, Csere P, Hoinkis C, Rothe G, Zahn P, Alheit H, Drechsler D, Herrmann T, Alberti W, Schwarz R, Graefen M, Kr?ll A, Rudat V, Huland H, Fehr C, Baum C, Glocker S, N?sslin F, Heil T, Lemnitzer H, Knips M, Baumgart O, Thiem W, Kloetzer KH, Hoffmann L, Neu B, H?ltenschmidt B, Sautter-Bihl ML, Micke O, Seegenschmiedt MH, K?ppen D, Klautke G, Fietkau R, Schultze J, Schlichting G, Kimmig B, Glatzel M, Fr?hlich D, B?secke S, Krau? A, Strau? D, Buth KJ, B?hme R, Oehler W, Bottke D, Keilholz U, Heufelder K, Wiegel T, Hinkelbein W, R?del C, Papadopoulos T, R?del F, Lubgan D, Distel L, Grabenbauer GG, Sak A, St?ben G, P?ttgen C, Grehl S, Stuschke M, M?ller K, Pfaffendorf C, Mayerhofer A, K?hn FM, Ring J, van Beuningen D, Meineke V, Neubauer S, Keller U, Wittlinger M, Riesenbeck D, Greve B, Exeler R, Ibrahim M, Liebscher C, Severin E, P?tter R, Hammer J, Hildebrandt G, Beckmann MW, Fehlauer F, Tribius S, Bajrovic A, H?ller U, Rades D, Grehn C, Hensley F, Berns C, Wannenmacher M, Semrau S, Reimer T, Gerber B, Ketterer P, Koepcke E, H?nsgen G, Strau? HG, Dunst J, F?ller J, Kalb S, Wendt T, Weitmann HD, Waldh?usl C, Knocke TH, Lamprecht U, Classen J, Kaulich TW, Aydeniz B, Wiezorek T, Scheithauer M, Lutterbach J, Bartelt S, Frommhold H, Lambert J, Hornung D, Swiderski S, Walke M, Siefert A, P?llinger B, Krimmel K, Schaffer M, Koelbl O, Bratengeier K, Vordermark D, Flentje M, Hero B, Berthold F, Combs SE, et al. [Not Available]. Strahlenther Onkol. 2004 Jun; 180 Suppl 1:5-87. PMID: 27137922.
      Citations:    Fields:    
    268. Jensen M, Tawadros S, Sedlacek HH, Schultze JL, Berthold F. NK cell depletion diminish tumour-specific B cell responses. Immunol Lett. 2004 May 15; 93(2-3):205-10. PMID: 15158618.
      Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    269. Vonderheide RH, Domchek SM, Schultze JL, George DJ, Hoar KM, Chen DY, Stephans KF, Masutomi K, Loda M, Xia Z, Anderson KS, Hahn WC, Nadler LM. Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. Clin Cancer Res. 2004 Feb 01; 10(3):828-39. PMID: 14871958.
      Citations: 64     Fields:    Translation:HumansCellsCTClinical Trials
    270. Debey S, Schoenbeck U, Hellmich M, Gathof BS, Pillai R, Zander T, Schultze JL. Comparison of different isolation techniques prior gene expression profiling of blood derived cells: impact on physiological responses, on overall expression and the role of different cell types. Pharmacogenomics J. 2004; 4(3):193-207. PMID: 15037859.
      Citations: 83     Fields:    Translation:HumansCells
    271. Schultze JL, Fiore F, von Bergwelt-Baildon M. DCs in lymphoma--biology and therapeutic aspects. Cytotherapy. 2004; 6(2):138-47. PMID: 15203990.
      Citations:    Fields:    Translation:HumansCells
    272. Schwientek T, Von Bergwelt-Baildon MS, Schultze JL, Finn O, Hanisch FG. O-Linked glycans control glycoprotein processing by antigen-presenting cells: a biochemical approach to the molecular aspects of MUC1 processing by dendritic cells. Eur J Immunol. 2003 Dec; 33(12):3242-54. PMID: 14635032.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    273. Jensen M, Ernestus K, Kemshead J, Klehr M, Von Bergwelt-Baildon MS, Schultze JL, Berthold F, Schink?the T. The bi-specific CD3 x NCAM antibody: a model to preactivate T cells prior to tumour cell lysis. Clin Exp Immunol. 2003 Nov; 134(2):253-63. PMID: 14616785; PMCID: PMC1808859.
      Citations: 2     Fields:    Translation:HumansCells
    274. Hirano N, Butler MO, Von Bergwelt-Baildon MS, Maecker B, Schultze JL, O'Connor KC, Schur PH, Kojima S, Guinan EC, Nadler LM. Autoantibodies frequently detected in patients with aplastic anemia. Blood. 2003 Dec 15; 102(13):4567-75. PMID: 12947009.
      Citations: 35     Fields:    Translation:HumansCells
    275. Maecker B, Sherr DH, Vonderheide RH, von Bergwelt-Baildon MS, Hirano N, Anderson KS, Xia Z, Butler MO, Wucherpfennig KW, O'Hara C, Cole G, Kwak SS, Ramstedt U, Tomlinson AJ, Chicz RM, Nadler LM, Schultze JL. The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells. Blood. 2003 Nov 01; 102(9):3287-94. PMID: 12869499.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    276. Maecker B, Anderson KS, von Bergwelt-Baildon MS, Weller E, Vonderheide RH, Richardson PG, Schlossman RL, Menezes IA, Xia Z, Munshi NC, Anderson KC, Nadler LM, Schultze JL. Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma. Br J Haematol. 2003 Jun; 121(6):842-8. PMID: 12786794.
      Citations: 15     Fields:    Translation:HumansCells
    277. Nolte A, Scheffold C, Slotty J, Huenefeld C, Schultze JL, Grabbe S, Berdel WE, Kienast J. Generation of melanoma-specific cytotoxic T lymphocytes for allogeneic immunotherapy. J Immunother. 2003 May-Jun; 26(3):257-69. PMID: 12806279.
      Citations: 5     Fields:    Translation:HumansCells
    278. Schmollinger JC, Vonderheide RH, Hoar KM, Maecker B, Schultze JL, Hodi FS, Soiffer RJ, Jung K, Kuroda MJ, Letvin NL, Greenfield EA, Mihm M, Kutok JL, Dranoff G. Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3398-403. PMID: 12626761; PMCID: PMC152304.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    279. Nadler LM, Schultze JL. From genomics to cancer vaccines: patient-tailored or universal vaccines? Curr Opin Mol Ther. 2002 Dec; 4(6):572-6. PMID: 12596359.
      Citations: 3     Fields:    Translation:HumansAnimals
    280. Schultze JL. Degeneracy instead of specificity: is this a solution to cancer immunotherapy? Trends Immunol. 2002 Jul; 23(7):343-4; author reply 344-5. PMID: 12103351.
      Citations: 2     Fields:    Translation:HumansCells
    281. Gross DA, Alves P, Schultze JL, Faure O, Tourdot S, Chouaib S, Nadler LM, Vonderheide RH, Cardoso AA, Kosmatopoulos K, Scardino A, Graff-Dubois S, Lemonnier FA. HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy. J Immunol. 2002 Jun 01; 168(11):5900-6. PMID: 12023395.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    282. Thomas RK, Kallenborn A, Wickenhauser C, Schultze JL, Draube A, Vockerodt M, Re D, Diehl V, Wolf J. Constitutive expression of c-FLIP in Hodgkin and Reed-Sternberg cells. Am J Pathol. 2002 Apr; 160(4):1521-8. PMID: 11943736; PMCID: PMC1867202.
      Citations: 16     Fields:    Translation:HumansCells
    283. Carideo EG, Neuberg D, Schultze J, Munoz O, Marks PW, Donovan JW, Chillemi AC, O'Connell P, Freedman AS, Husson H. Gene expression profiling of follicular lymphoma and normal germinal center B cells using cDNA arrays. Blood. 2002 Jan 01; 99(1):282-9. PMID: 11756183.
      Citations: 33     Fields:    Translation:HumansCells
    284. Schultze JL, Bohlen H. Influence of genomics on cancer vaccine development from guess to prediction. Curr Pharm Des. 2002; 8(19):1735-48. PMID: 12171545.
      Citations:    Fields:    Translation:Humans
    285. Vonderheide RH, Schultze JL, Anderson KS, Maecker B, Butler MO, Xia Z, Kuroda MJ, von Bergwelt-Baildon MS, Bedor MM, Hoar KM, Schnipper DR, Brooks MW, Letvin NL, Stephans KF, Wucherpfennig KW, Hahn WC, Nadler LM. Equivalent induction of telomerase-specific cytotoxic T lymphocytes from tumor-bearing patients and healthy individuals. Cancer Res. 2001 Dec 01; 61(23):8366-70. PMID: 11731409.
      Citations: 17     Fields:    Translation:HumansCells
    286. Husson H, Carideo EG, Cardoso AA, Lugli SM, Neuberg D, Munoz O, de Leval L, Schultze J, Freedman AS. MCP-1 modulates chemotaxis by follicular lymphoma cells. Br J Haematol. 2001 Dec; 115(3):554-62. PMID: 11736935.
      Citations: 14     Fields:    Translation:HumansCells
    287. Maecker B, Anderson KS, Vonderheide RH, Schultze JL. Linking genomics to immunotherapy by reverse immunology--'immunomics' in the new millennium. Curr Mol Med. 2001 Nov; 1(5):609-19. PMID: 11899235.
      Citations: 7     Fields:    Translation:HumansAnimals
    288. Vonderheide RH, Anderson KS, Hahn WC, Butler MO, Schultze JL, Nadler LM. Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase. Clin Cancer Res. 2001 Nov; 7(11):3343-8. PMID: 11705846.
      Citations: 28     Fields:    Translation:HumansCells
    289. Vonderheide RH, Butler MO, Liu JF, Battle TE, Hirano N, Gribben JG, Frank DA, Schultze JL, Nadler LM. CD40 activation of carcinoma cells increases expression of adhesion and major histocompatibility molecules but fails to induce either CD80/CD86 expression or T cell alloreactivity. Int J Oncol. 2001 Oct; 19(4):791-8. PMID: 11562757.
      Citations: 1     Fields:    Translation:HumansCells
    290. del Valle F, Berdel WE, Willich NA, Reers B, Hiddemann W, Grothaus-Pinke B, Reinartz G, Brockmann J, Temmesfeld A, Schmitz R, Probst A, Jaenke G, Bodenstein H, Junker A, Pott C, Schultze J, Heinecke A, Parwaresch R, Tiemann M, German Multicenter Study Group, Koch P, R?be C. Primary gastrointestinal non-Hodgkin's lymphoma: I. Anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German Multicenter Study GIT NHL 01/92. J Clin Oncol. 2001 Sep 15; 19(18):3861-73. PMID: 11559724.
      Citations: 135     Fields:    Translation:Humans
    291. del Valle F, Berdel WE, Willich NA, Reers B, Hiddemann W, Grothaus-Pinke B, Reinartz G, Brockmann J, Temmesfeld A, Schmitz R, Probst A, Jaenke G, Bodenstein H, Junker A, Pott C, Schultze J, Heinecke A, Parwaresch R, Tiemann M, German Multicenter Study Group, Koch P, R?be C. Primary gastrointestinal non-Hodgkin's lymphoma: II. Combined surgical and conservative or conservative management only in localized gastric lymphoma--results of the prospective German Multicenter Study GIT NHL 01/92. J Clin Oncol. 2001 Sep 15; 19(18):3874-83. PMID: 11559725.
      Citations: 57     Fields:    Translation:HumansCTClinical Trials
    292. Trojan A, Schultze JL, Witzens M, Vonderheide RH, Ladetto M, Donovan JW, Gribben JG. Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies. Nat Med. 2000 Jun; 6(6):667-72. PMID: 10835683.
      Citations: 33     Fields:    Translation:HumansCells
    293. Schultze J, Matula C, Anton JV, Gst?ttner W. [Tumors of the anterior skull base. Effects of perioperative imaging on adjuvant radiotherapy planning]. Rontgenpraxis. 2000; 53(1):10-5. PMID: 10943137.
      Citations:    Fields:    Translation:Humans
    294. Kaya A, Kimmig B, Schultze J. [Results of radiotherapy in brain metastasis]. Rontgenpraxis. 2000; 53(3):102-9. PMID: 11131110.
      Citations:    Fields:    Translation:Humans
    295. Schultze J, Johnson P. A stimulating new target for cancer immunotherapy. Lancet. 1999 Oct 09; 354(9186):1225-7. PMID: 10520628.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    296. Vonderheide RH, Hahn WC, Schultze JL, Nadler LM. The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes. Immunity. 1999 Jun; 10(6):673-9. PMID: 10403642.
      Citations: 129     Fields:    Translation:HumansCells
    297. Schultze JL, Nadler LM. T cell mediated immunotherapy for B cell lymphoma. J Mol Med (Berl). 1999 Mar; 77(3):322-31. PMID: 10090595.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    298. Schultze JL, Donovan JW, Gribben JG. Minimal residual disease detection after myeloablative chemotherapy in chronic lymphatic leukemia. J Mol Med (Berl). 1999 Feb; 77(2):259-65. PMID: 10023779.
      Citations: 3     Fields:    Translation:HumansCells
    299. Schultze JL, Michalak S, Lowne J, Wong A, Gilleece MH, Gribben JG, Nadler LM. Human non-germinal center B cell interleukin (IL)-12 production is primarily regulated by T cell signals CD40 ligand, interferon gamma, and IL-10: role of B cells in the maintenance of T cell responses. J Exp Med. 1999 Jan 04; 189(1):1-12. PMID: 9874559; PMCID: PMC1887700.
      Citations: 29     Fields:    Translation:HumansCells
    300. Hart DN, Schultze JL, Stewart AK. Presentation of tumor antigens. Semin Hematol. 1999 Jan; 36(1 Suppl 3):21-5. PMID: 9989485.
      Citations: 3     Fields:    Translation:HumansCells
    301. Schultze JL. Why do B cell lymphoma fail to elicit clinically sufficient T cell immune responses? Leuk Lymphoma. 1999 Jan; 32(3-4):223-36. PMID: 10037020.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    302. Schultze JL, Gribben JG, Nadler LM. Tumor-specific adoptive T-cell therapy for CD40+ B-cell malignancies. Curr Opin Oncol. 1998 Nov; 10(6):542-7. PMID: 9818233.
      Citations:    Fields:    Translation:HumansAnimalsCells
    303. Bleul CC, Schultze JL, Springer TA. B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement. J Exp Med. 1998 Mar 02; 187(5):753-62. PMID: 9480985; PMCID: PMC2212170.
      Citations: 50     Fields:    Translation:HumansCells
    304. Ghia P, Boussiotis VA, Schultze JL, Cardoso AA, Dorfman DM, Gribben JG, Freedman AS, Nadler LM. Unbalanced expression of bcl-2 family proteins in follicular lymphoma: contribution of CD40 signaling in promoting survival. Blood. 1998 Jan 01; 91(1):244-51. PMID: 9414291.
      Citations: 23     Fields:    Translation:HumansCells
    305. Dorfman DM, Schultze JL, Shahsafaei A, Michalak S, Gribben JG, Freeman GJ, Pinkus GS, Nadler LM. In vivo expression of B7-1 and B7-2 by follicular lymphoma cells can prevent induction of T-cell anergy but is insufficient to induce significant T-cell proliferation. Blood. 1997 Dec 01; 90(11):4297-306. PMID: 9373240.
      Citations: 16     Fields:    Translation:HumansCells
    306. Schultze JL, Michalak S, Seamon MJ, Dranoff G, Jung K, Daley J, Delgado JC, Gribben JG, Nadler LM. CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy. J Clin Invest. 1997 Dec 01; 100(11):2757-65. PMID: 9389740; PMCID: PMC508480.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    307. Schultze JL. Vaccination as immunotherapy for B cell lymphoma. Hematol Oncol. 1997 Aug; 15(3):129-39. PMID: 9600112.
      Citations:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
    308. Schultze JL, Seamon MJ, Michalak S, Gribben JG, Nadler LM. Autologous tumor infiltrating T cells cytotoxic for follicular lymphoma cells can be expanded in vitro. Blood. 1997 May 15; 89(10):3806-16. PMID: 9160688.
      Citations: 14     Fields:    Translation:HumansCells
    309. Gribben JG, Cardoso AA, Schultze JL, Nadler LM. Biologic response modifiers in acute lymphoblastic leukemia. Leukemia. 1997 May; 11 Suppl 4:S31-3. PMID: 9179280.
      Citations:    Fields:    Translation:HumansCells
    310. Weikert S, Freyer D, Weih M, Isaev N, Busch C, Schultze J, Megow D, Dirnagl U. Rapid Ca2+-dependent NO-production from central nervous system cells in culture measured by NO-nitrite/ozone chemoluminescence. Brain Res. 1997 Feb 14; 748(1-2):1-11. PMID: 9067439.
      Citations: 7     Fields:    Translation:AnimalsCells
    311. Gribben JG, Schultze JL. The detection of minimal residual disease: implications for bone marrow transplantation. Cancer Treat Res. 1997; 77:99-120. PMID: 9071500.
      Citations: 1     Fields:    Translation:Humans
    312. Hall KT, Boumsell L, Schultze JL, Boussiotis VA, Dorfman DM, Cardoso AA, Bensussan A, Nadler LM, Freeman GJ. Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11780-5. PMID: 8876214; PMCID: PMC38135.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    313. Lindauer U, Megow D, Schultze J, Weber JR, Dirnagl U. Nitric oxide synthase inhibition does not affect somatosensory evoked potentials in the rat. Neurosci Lett. 1996 Oct 04; 216(3):207-10. PMID: 8897494.
      Citations: 9     Fields:    Translation:Animals
    314. Cardoso AA, Schultze JL, Boussiotis VA, Freeman GJ, Seamon MJ, Laszlo S, Billet A, Sallan SE, Gribben JG, Nadler LM. Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen. Blood. 1996 Jul 01; 88(1):41-8. PMID: 8704200.
      Citations: 36     Fields:    Translation:HumansCells
    315. Schultze J, Nadler LM, Gribben JG. B7-mediated costimulation and the immune response. Blood Rev. 1996 Jun; 10(2):111-27. PMID: 8813343.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    316. Schultze JL, Gribben JG. Minimal residual disease in non-Hodgkin's lymphoma. Biomed Pharmacother. 1996; 50(9):451-8. PMID: 8991117.
      Citations:    Fields:    Translation:Humans
    317. Schultze JL, Cardoso AA, Freeman GJ, Seamon MJ, Daley J, Pinkus GS, Gribben JG, Nadler LM. Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity. Proc Natl Acad Sci U S A. 1995 Aug 29; 92(18):8200-4. PMID: 7545296; PMCID: PMC41124.
      Citations: 52     Fields:    Translation:HumansCells
    318. Blume J, Wendhausen H, Hebbinghaus D, Eilf K, Schultze J, Kimmig BN, Zimmermann JS, Kov?cs G. [The new possibilities of digital luminescence radiography (DLR) and digital imaging data processing for the making of field verification images]. Strahlenther Onkol. 1995 Jun; 171(6):332-9. PMID: 7597619.
      Citations: 1     Fields:    Translation:Humans
    319. Eilf K, Zimmermann J, Kimmig B, Schultze J. [The use of contrast media for quality assurance in radiotherapy planning]. Strahlenther Onkol. 1995 Feb; 171(2):100-4; discussion 105. PMID: 7863422.
      Citations:    Fields:    Translation:Humans
    320. Veelken H, Jesuiter H, Mackensen A, Kulmburg P, Schultze J, Rosenthal F, Mertelsmann R, Lindemann A. Primary fibroblasts from human adults as target cells for ex vivo transfection and gene therapy. Hum Gene Ther. 1994 Oct; 5(10):1203-10. PMID: 7849093.
      Citations: 6     Fields:    Translation:HumansCells
    321. Digel W, Schultze J, Kunzmann R, Mertelsmann R, Lindemann A. Poor prognosis of prethymic phenotype acute lymphoblastic leukemia (pre-T-ALL). Leukemia. 1994 Aug; 8(8):1406-8. PMID: 8057681.
      Citations: 1     Fields:    Translation:HumansCells
    322. Stettin A, Berg PA, Schultze JL. Demonstration of specifically sensitized lymphocytes in patients treated with an aqueous mistletoe extract (Viscum album L.). Klin Wochenschr. 1991 Jun 18; 69(9):397-403. PMID: 1921242.
      Citations: 5     Fields:    Translation:HumansCells
    323. Schultze JL, Stechemesser E, Berg PA, Stettin A. Anti-mistletoe lectin antibodies are produced in patients during therapy with an aqueous mistletoe extract derived from Viscum album L. and neutralize lectin-induced cytotoxicity in vitro. Klin Wochenschr. 1990 Sep 14; 68(18):896-900. PMID: 2124308.
      Citations: 8     Fields:    Translation:HumansAnimals

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