Next Generation Sequencing Competence Network

Next Generation Sequencing Competence Network

e.g. CCGA
(min 2 characters)

Stephan Ossowski

Prof.
University of Tuebingen
Institute for Medical Genetics and Applied Genomics, Institute for Medical Genetics and Applied Genomics
Calwerstraße 7/8, 72076 Tübingen, Germany
Tübingen 72076
+49 152 3851794
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Weisschuh N, Mazzola P, Zuleger T, Schaeferhoff K, K?hlewein L, Kort?m F, Witt D, Liebmann A, Falb R, Pohl L, Reith M, St?hn LG, Bertrand M, M?ller A, Casadei N, Kelemen O, Kelbsch C, Kernstock C, Richter P, Sadler F, Demidov G, Sch?tz L, Admard J, Sturm M, Grasshoff U, Tonagel F, Heinrich T, Nasser F, Wissinger B, Ossowski S, Kohl S, Riess O, Stingl K, Haack TB. Diagnostic genome sequencing improves diagnostic yield: a prospective single-centre study in 1000 patients with inherited eye diseases. J Med Genet. 2023 Sep 21. PMID: 37734845.
      Citations: 3     Fields:    Translation:HumansCells
    2. Liebmann A, Admard J, Armeanu-Ebinger S, Wild H, Abele M, Gschwind A, Seibel-Kelemen O, Seitz C, Bonzheim I, Riess O, Demidov G, Sturm M, Schadeck M, Pogoda M, Bien E, Krawczyk M, J?ttner E, Mentzel T, Cesen M, Pfaff E, Kunc M, Forchhammer S, Forschner A, Leiter-St?ppke U, Eigentler TK, Schneider DT, Schroeder C, Ossowski S, Brecht IB. UV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescents. EBioMedicine. 2023 Sep 14; 96:104797. PMID: 37716236; PMCID: PMC10511785.
      Citations:    Fields:    
    3. Park J, Tucci A, Cipriani V, Demidov G, Rocca C, Senderek J, Butryn M, Velic A, Lam T, Galanaki E, Cali E, Vestito L, Maroofian R, Deininger N, Rautenberg M, Admard J, Hahn GA, Bartels C, van Os NJH, Horvath R, Chinnery PF, Tiet MY, Hewamadduma C, Hadjivassiliou M, Downes SM, N?meth AH, Tofaris GK, Genomics England Research Consortium, Wood NW, Hayer SN, Bender F, Menden B, Cordts I, Klein K, Nguyen HP, Krauss JK, Blahak C, Strom TM, Sturm M, van de Warrenburg B, Lerche H, Macek B, Synofzik M, Ossowski S, Timmann D, Wolf ME, Smedley D, Riess O, Sch?ls L, Houlden H, Haack TB, Hengel H. Heterozygous UCHL1 loss-of-function variants cause a neurodegenerative disorder with spasticity, ataxia, neuropathy, and optic atrophy. Genet Med. 2023 Aug 31; 100961. PMID: 37650884.
      Citations:    Fields:    
    4. Schroeder C, Faust U, Krau?e L, Liebmann A, Abele M, Demidov G, Sch?tz L, Kelemen O, Pohle A, Gau? S, Sturm M, Roggia C, Streiter M, Buchert R, Armenau-Ebinger S, Nann D, Beschorner R, Handgretinger R, Ebinger M, Lang P, Holzer U, Skokowa J, Ossowski S, Haack TB, Mau-Holzmann UA, Dufke A, Riess O, Brecht IB. Clinical trio genome sequencing facilitates the interpretation of variants in cancer predisposition genes in paediatric tumour patients. Eur J Hum Genet. 2023 10; 31(10):1139-1146. PMID: 37507557; PMCID: PMC10545765.
      Citations: 3     Fields:    Translation:Humans
    5. Ossowski S, Lyon L, Linehan E, Gordon NP, Egorova O, Mark B, Beringer K, Abbe T, Shirazi A, Weldon C, Trosman J, Ravelo A, Liu R. Advance Directives for Patients With Breast Cancer: Applying the Right Info/Right Care/Right Patient/Right Time Oncology Model. Perm J. 2023 09 15; 27(3):30-36. PMID: 37255340; PMCID: PMC10502389.
      Citations:    Fields:    Translation:Humans
    6. Podar IV, Gutmann DAP, Harmuth F, Haack TB, Ossowski S, Hengel H, Bornemann A, Sch?ls L, Neuhaus O. First case of adult onset neuronal intranuclear inclusion disease with both typical radiological signs and NOTCH2NLC repeat expansions in a Caucasian individual. Eur J Neurol. 2023 09; 30(9):2854-2858. PMID: 37271829.
      Citations:    Fields:    Translation:HumansCells
    7. Illert AL, Stenzinger A, Bitzer M, Horak P, Gaidzik VI, M?ller Y, Beha J, ?ner ?, Schmitt F, La?mann S, Ossowski S, Schaaf CP, Hallek M, Br?mmendorf TH, Albers P, Fehm T, Brossart P, Glimm H, Schadendorf D, Bleckmann A, Brandts CH, Esposito I, Mack E, Peters C, Bokemeyer C, Fr?hling S, Kindler T, Alg?l H, Heinemann V, D?hner H, Bargou R, Ellenrieder V, Hillemanns P, Lordick F, Hochhaus A, Beckmann MW, Pukrop T, Trepel M, Sundmacher L, Wesselmann S, Nettekoven G, Kohlhuber F, Heinze O, Budczies J, Werner M, Nikolaou K, Beer AJ, Tabatabai G, Weichert W, Keilholz U, Boerries M, Kohlbacher O, Duyster J, Thimme R, Seufferlein T, Schirmacher P, Malek NP. The German Network for Personalized Medicine to enhance patient care and translational research. Nat Med. 2023 Jun; 29(6):1298-1301. PMID: 37280276.
      Citations: 5     Fields:    Translation:Humans
    8. Stellmach C, Sass J, Auber B, Boeker M, Wienker T, Heidel AJ, Benary M, Schumacher S, Ossowski S, Klauschen F, M?ller Y, Schmutzler R, Ustjanzew A, Werner P, Tomczak A, H?lter T, Thun S. Creation of a structured molecular genomics report for Germany as a local adaption of HL7's Genomic Reporting Implementation Guide. J Am Med Inform Assoc. 2023 05 19; 30(6):1179-1189. PMID: 37080557; PMCID: PMC10198526.
      Citations:    Fields:    
    9. Rodi M, Gross C, Sandri TL, Berner L, Marcet-Houben M, Kocak E, Pogoda M, Casadei N, K?hler C, Kreidenweiss A, Agnandji ST, Gabald?n T, Ossowski S, Held J. Whole genome analysis of two sympatric human Mansonella: Mansonella perstans and Mansonella sp "DEUX". Front Cell Infect Microbiol. 2023; 13:1159814. PMID: 37124042; PMCID: PMC10145164.
      Citations:    Fields:    Translation:HumansAnimalsCells
    10. Mittelstadt S, Kelemen O, Admard J, Gschwind A, Koch A, W?rz S, Oberlechner E, Engler T, Bonzheim I, Staebler A, Weidner N, Stubenrauch F, Iftner T, Riess O, Schroeder C, Kommoss S, Ossowski S. Detection of circulating cell-free HPV DNA of 13 HPV types for patients with cervical cancer as potential biomarker to monitor therapy response and to detect relapse. Br J Cancer. 2023 06; 128(11):2097-2103. PMID: 36973448; PMCID: PMC10206065.
      Citations: 2     Fields:    Translation:Humans
    11. Renovanz M, Kurz SC, Rieger J, Walter B, Becker H, Hille H, Bombach P, Rieger D, Grosse L, H?usser L, Skardelly M, Merk DJ, Paulsen F, Hoffmann E, Gani C, Neumann M, Beschorner R, Rie? O, Roggia C, Schroeder C, Ossowski S, Armeanu-Ebinger S, Gschwind A, Biskup S, Schulze M, Fend F, Singer S, Zender L, Lengerke C, Brucker SY, Engler T, Forschner A, Stenzl A, Kohlbacher O, Nahnsen S, Gabernet G, Fillinger S, Bender B, Ernemann U, ?ner ?, Beha J, Malek HS, M?ller Y, Ruhm K, Tatagiba M, Schittenhelm J, Bitzer M, Malek N, Zips D, Tabatabai G. Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous system. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad012. PMID: 36915613; PMCID: PMC10007909.
      Citations: 3     
    12. Witt D, Faust U, Strobl-Wildemann G, Sturm M, Buchert R, Zuleger T, Admard J, Casadei N, Ossowski S, Haack TB, Rie? O, Schroeder C. Genome sequencing identifies complex structural MLH1 variant in unsolved Lynch syndrome. Mol Genet Genomic Med. 2023 06; 11(6):e2151. PMID: 36760167; PMCID: PMC10265068.
      Citations: 2     Fields:    Translation:HumansCells
    13. Roggia C, Armeanu-Ebinger S, Gschwind A, Seibel-Kelemen O, Hertler S, Faust U, Liebmann A, Haack TB, Neumann M, Bonzheim I, Forschner A, Kopp HG, Herster F, Hartkopf A, Bitzer M, Malek NP, Brecht IB, Ruhm K, M?ller Y, L?wenheim H, Ossowski S, Rie? OH, Schroeder C. Germline findings in patients with advanced malignancies screened with paired blood-tumour testing for personalised treatment approaches. Eur J Cancer. 2023 01; 179:48-55. PMID: 36495689.
      Citations:    Fields:    Translation:Humans
    14. Butler-Laporte G, Povysil G, Kosmicki JA, Cirulli ET, Drivas T, Furini S, Saad C, Schmidt A, Olszewski P, Korotko U, Quinodoz M, ?elik E, Kundu K, Walter K, Jung J, Stockwell AD, Sloofman LG, Jordan DM, Thompson RC, Del Valle D, Simons N, Cheng E, Sebra R, Schadt EE, Kim-Schulze S, Gnjatic S, Merad M, Buxbaum JD, Beckmann ND, Charney AW, Przychodzen B, Chang T, Pottinger TD, Shang N, Brand F, Fava F, Mari F, Chwialkowska K, Niemira M, Pula S, Baillie JK, Stuckey A, Salas A, Bello X, Pardo-Seco J, G?mez-Carballa A, Rivero-Calle I, Martin?n-Torres F, Ganna A, Karczewski KJ, Veerapen K, Bourgey M, Bourque G, Eveleigh RJ, Forgetta V, Morrison D, Langlais D, Lathrop M, Mooser V, Nakanishi T, Frithiof R, Hultstr?m M, Lipcsey M, Marincevic-Zuniga Y, Nordlund J, Schiabor Barrett KM, Lee W, Bolze A, White S, Riffle S, Tanudjaja F, Sandoval E, Neveux I, Dabe S, Casadei N, Motameny S, Alaamery M, Massadeh S, Aljawini N, Almutairi MS, Arabi YM, Alqahtani SA, Al Harthi FS, Almutairi A, Alqubaishi F, Alotaibi S, Binowayn A, Alsolm EA, El Bardisy H, Fawzy M, Cai F, Soranzo N, Butterworth A, COVID-19 Host Genetics Initiative, DeCOI Host Genetics Group, GEN-COVID Multicenter Study (Italy), Mount Sinai Clinical Intelligence Center, GEN-COVID consortium (Spain), GenOMICC Consortium, Japan COVID-19 Task Force, Regeneron Genetics Center, Geschwind DH, Arteaga S, Stephens A, Butte MJ, Boutros PC, Yamaguchi TN, Tao S, Eng S, Sanders T, Tung PJ, Broudy ME, Pan Y, Gonzalez A, Chavan N, Johnson R, Pasaniuc B, Yaspan B, Smieszek S, Rivolta C, Bibert S, Bochud PY, Dabrowski M, Zawadzki P, Sypniewski M, Kaja E, Chariyavilaskul P, Nilaratanakul V, Hirankarn N, Shotelersuk V, Pongpanich M, Phokaew C, Chetruengchai W, Tokunaga K, Sugiyama M, Kawai Y, Hasegawa T, Naito T, Namkoong H, Edahiro R, Kimura A, Ogawa S, Kanai T, Fukunaga K, Okada Y, Imoto S, Miyano S, Mangul S, Abedalthagafi MS, Zeberg H, Grzymski JJ, Washington NL, Ossowski S, Ludwig KU, Schulte EC, Riess O, Moniuszko M, Kwasniewski M, Mbarek H, Ismail SI, Verma A, Goldstein DB, Kiryluk K, Renieri A, Ferreira MAR, Richards JB. Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. PLoS Genet. 2022 11; 18(11):e1010367. PMID: 36327219; PMCID: PMC9632827.
      Citations: 13     Fields:    Translation:HumansCells
    15. Ossowski S, Neeman E, Borden C, Stram D, Giraldo L, Kotak D, Thomas S, Suga JM, Lin A, Liu R. Improving Time to Molecular Testing Results in Patients With Newly Diagnosed, Metastatic Non-Small-Cell Lung Cancer. JCO Oncol Pract. 2022 Nov; 18(11):e1874-e1884. PMID: 36191286.
      Citations: 4     Fields:    Translation:Humans
    16. Liu R, Weldon CB, Linehan E, Gordon N, Abbe T, Hennings M, James H, Katzel J, Ng C, Tomita M, Velotta JB, Ossowski S, Sakoda LC, Sprague SL, Dowling A, Beringer K, Ravelo A, Yu E, Trosman JR. Fostering a High-Functioning Team in Cancer Care Using the 4R Oncology Model: Assessment in a Large Health System and a Blueprint for Other Institutions. JCO Oncol Pract. 2023 01; 19(1):e125-e137. PMID: 36178937; PMCID: PMC10166419.
      Citations: 2     Fields:    Translation:Humans
    17. Banks KC, Ossowski S, Hung YY, Hsu DS, Ashiku SK, Patel AR, Velotta JB, Suga JM. Comparison of Survival by Multimodal Treatment Regimen Among Malignant Pleural Mesothelioma Patients in an Integrated Health System. Clin Lung Cancer. 2022 Dec; 23(8):694-701. PMID: 36216742.
      Citations: 1     Fields:    Translation:Humans
    18. Ossowski S, Hung YY, Banks K, Hsu D, Herrinton L, Ashiku S, Patel A, Suga JM, Velotta JB. Improving outcomes in malignant pleural mesothelioma in an integrated health care system. J Thorac Dis. 2022 Sep; 14(9):3352-3363. PMID: 36245635; PMCID: PMC9562545.
      Citations: 1     
    19. Park J, Tucci A, Cipriani V, Demidov G, Rocca C, Senderek J, Butryn M, Velic A, Lam T, Galanaki E, Cali E, Vestito L, Maroofian R, Deininger N, Rautenberg M, Admard J, Hahn GA, Bartels C, van Os NJH, Horvath R, Chinnery PF, Tiet MY, Hewamadduma C, Hadjivassiliou M, Tofaris GK, Genomics England Research Consortium, Wood NW, Hayer SN, Bender F, Menden B, Cordts I, Klein K, Nguyen HP, Krauss JK, Blahak C, Strom TM, Sturm M, van de Warrenburg B, Lerche H, Macek B, Synofzik M, Ossowski S, Timmann D, Wolf ME, Smedley D, Riess O, Sch?ls L, Houlden H, Haack TB, Hengel H. Heterozygous UCHL1 loss-of-function variants cause a neurodegenerative disorder with spasticity, ataxia, neuropathy, and optic atrophy. Genet Med. 2022 10; 24(10):2079-2090. PMID: 35986737.
      Citations: 2     Fields:    Translation:Humans
    20. Fawcett KA, Shrine N, Paynton ML, Sayers I, Wain LV, Hollox EJ, Demidov G, Ossowski S. Exome-wide analysis of copy number variation shows association of the human leukocyte antigen region with asthma in UK Biobank. BMC Med Genomics. 2022 05 21; 15(1):119. PMID: 35597955; PMCID: PMC9124406.
      Citations: 2     Fields:    Translation:Humans
    21. Dufke A, Hoopmann M, Waldm?ller S, Prodan NC, Beck-W?dl S, Grasshoff U, Heinrich T, Riess A, Kehrer M, Falb RJ, Liebmann A, Roggia C, Stampfer M, Schadeck M, M?ller AJ, Grimmel M, St?be P, Gauck D, Buchert-Lo R, Baumann S, Sch?ferhoff K, Bertrand M, Menden B, Sturm M, Sch?tz L, Riess O, Ossowski S, Haack TB, Kagan KO. A single center experience of prenatal parent-fetus trio exome sequencing for pregnancies with congenital anomalies. Prenat Diagn. 2022 06; 42(7):901-910. PMID: 35574990.
      Citations:    Fields:    Translation:Humans
    22. Eckardt J, Schroeder C, Martus P, Armeanu-Ebinger S, Kelemen O, Gschwind A, Bonzheim I, Eigentler T, Amaral T, Ossowski S, Rie? O, Flatz L, Garbe C, Forschner A. TMB and BRAF mutation status are independent predictive factors in high-risk melanoma patients with adjuvant anti-PD-1 therapy. J Cancer Res Clin Oncol. 2023 Feb; 149(2):833-840. PMID: 35192052; PMCID: PMC9931777.
      Citations: 4     Fields:    Translation:Humans
    23. Sauter-Meyerhoff C, Bohnert R, Mazzola P, Kandabarau S, Winter S, Herrmann L, Rausch S, Fend F, Scharpf M, Stenzl A, Ossowski S, Bedke J, Schwab M, Schaeffeler E, St?hler V, B?ttner FA, Hennenlotter J. Characterization of Genetic Heterogeneity in Recurrent Metastases of Renal Cell Carcinoma. Cancers (Basel). 2021 Dec 10; 13(24). PMID: 34944839; PMCID: PMC8699544.
      Citations: 1     
    24. Park J, Reilaender A, Petry-Schmelzer JN, St?be P, Cordts I, Harmuth F, Rautenberg M, Woerz SE, Demidov G, Sturm M, Ossowski S, Schwaibold EMC, Wunderlich G, Paus S, Saft C, Haack TB. Transcript-Specific Loss-of-Function Variants in VPS16 Are Enriched in Patients With Dystonia. Neurol Genet. 2022 Feb; 8(1):e644. PMID: 34901436; PMCID: PMC8656243.
      Citations: 6     
    25. Falb RJ, Klein W, Grimmel M, Grasshoff U, Spranger S, Gauck D, Kuechler A, Dikow N, Schwaibold EMC, Schmidt C, Averdunk L, Buchert R, Heinrich T, Prodan N, Park J, Kehrer M, Sturm M, Kelemen O, Hartmann S, Emmerich D, Hirt N, Neumann A, Kristiansen G, Gembruch U, Haen S, Siebert R, Hentze S, Hoopmann M, Ossowski S, Tekesin I, Distelmaier F, Riess O, Kagan KO, Dufke A, Haack TB, M?ller AJ, St?be P, Horn D, Waldm?ller S, Beck-W?dl S, Gl?ser D. Bi-allelic loss-of-function variants in KIF21A cause severe fetal akinesia with arthrogryposis multiplex. J Med Genet. 2023 01; 60(1):48-56. PMID: 34740919; PMCID: PMC9811090.
      Citations: 12     Fields:    Translation:HumansAnimals
    26. Cordts I, Blandfort M, Demidov G, Park J, Armeanu-Ebinger S, Roggia C, Faust U, Haack TB, Schroeder C, Ossowski S. Detection of mobile elements insertions for routine clinical diagnostics in targeted sequencing data. Mol Genet Genomic Med. 2021 12; 9(12):e1807. PMID: 34491624; PMCID: PMC8683623.
      Citations: 2     Fields:    Translation:HumansCells
    27. Peng C, Dieck S, Schmid A, Knaus A, Wenzel M, Mehnert L, Zirn B, Rosnev S, Kamphans T, Nadav G, Fleischer N, Krawitz P, Ahmad A, Haack T, Ossowski S, Wagner M, Brunet T, Ehmke N, Danyel M, Fr?hlich H. CADA: phenotype-driven gene prioritization based on a case-enriched knowledge graph. NAR Genom Bioinform. 2021 Sep; 3(3):lqab078. PMID: 34514393; PMCID: PMC8415429.
      Citations: 10     
    28. Vissers LELM, de Voer RM, Laurie S, Matalonga L, Gilissen C, 't Hoen PAC, Brunner HG, Brookes AJ, Rath A, Gumus G, Hoogerbrugge N, Swertz M, Spalding D, Hoischen A, Beltran S, Solve-RD consortium, Zurek B, Ellwanger K, Sch?le R, Synofzik M, T?pf A, Ossowski S, Vitobello A, Schulze-Hentrich JM, Riess O, Bonne G, Verloes A, Evangelista T, Harmuth T, Graessner H. Correction to: Solve-RD: systematic pan-European data sharing and collaborative analysis to solve rare diseases. Eur J Hum Genet. 2021 Sep; 29(9):1459-1461. PMID: 34385672; PMCID: PMC8440583.
      Citations:    Fields:    
    29. Ossowski S, Kammerer A, Stram D, Piazza-DeLap L, Basch E, Katzel JA. Patient-Reported Outcomes Integrated Within an Electronic Medical Record in Patients With Head and Neck Cancer. JCO Clin Cancer Inform. 2021 08; 5:842-848. PMID: 34406801.
      Citations: 3     Fields:    Translation:Humans
    30. Bernhart SH, Siebert R, Cardona Gloria Y, Fillinger S, Wolz OO, Dickh?fer S, Admard J, Ossowski S, Nahnsen S, Weber ANR. Absence of Non-Canonical, Inhibitory MYD88 Splice Variants in B Cell Lymphomas Correlates With Sustained NF-?B Signaling. Front Immunol. 2021; 12:616451. PMID: 34163463; PMCID: PMC8215704.
      Citations: 6     Fields:    Translation:HumansCells
    31. Vissers LELM, de Voer RM, Laurie S, Matalonga L, Gilissen C, 't Hoen PAC, Brunner HG, Brookes AJ, Rath A, Gumus G, Hoogerbrugge N, Swertz M, Spalding D, Hoischen A, Beltran S, Solve-RD consortium, Zurek B, Ellwanger K, Sch?le R, Synofzik M, T?pf A, Ossowski S, Vitobello A, Schulze-Hentrich JM, Riess O, Bonne G, Verloes A, Evangelista T, Harmuth T, Graessner H. Solve-RD: systematic pan-European data sharing and collaborative analysis to solve rare diseases. Eur J Hum Genet. 2021 09; 29(9):1325-1331. PMID: 34075208; PMCID: PMC8440542.
      Citations: 36     Fields:    Translation:Humans
    32. Deutsche COVID-19 OMICS Initiate (DeCOI), Singh Y, Trautwein C, Fendel R, Krickeberg N, Berezhnoy G, Bissinger R, Ossowski S, Salker MS, Casadei N, Riess O. SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells. Heliyon. 2021 Jun; 7(6):e07147. PMID: 34075347; PMCID: PMC8159709.
      Citations: 11     
    33. Singer S, Gazou A, Sturm M, Demidov G, Mazzola P, Riess O, Ossowski S, Dufke A. New euchromatic variant dup(11)(p15.3p15.1) transmitted through two generations defined by low coverage whole genome sequencing. Am J Med Genet A. 2021 10; 185(10):3053-3056. PMID: 34042264.
      Citations: 1     Fields:    Translation:HumansCells
    34. Danko D, Afshin EE, Ahsanuddin S, Bhattacharya C, Butler DJ, Chng KR, Donnellan D, Hecht J, Jackson K, Kuchin K, Karasikov M, Lyons A, Mak L, Meleshko D, Mustafa H, Mutai B, Neches RY, Ng A, Nikolayeva O, Nikolayeva T, Png E, Ryon KA, Sanchez JL, Shaaban H, Sierra MA, Thomas D, Young B, Abudayyeh OO, Alicea J, Bhattacharyya M, Blekhman R, Castro-Nallar E, Chatziefthimiou AD, Crawford RW, De Filippis F, Deng Y, Dybwad M, Elhaik E, Ercolini D, Frolova A, Gankin D, Gootenberg JS, Graf AB, Green DC, Hajirasouliha I, Hastings JJA, Hernandez M, Iraola G, Jang S, Kahles A, Kelly FJ, Knights K, Kyrpides NC, Lee PKH, Leung MHY, Ljungdahl PO, Mason-Buck G, McGrath K, Meydan C, Mongodin EF, Nagarajan N, Nieto-Caballero M, Oliveira M, Osuolale OO, Paez-Espino D, Richard H, Schriml LM, Semmler T, Sezerman OU, Shi L, Shi T, Siam R, Song LH, Suzuki H, Court DS, Tighe SW, Tong X, Udekwu KI, Ugalde JA, Valentine B, Vassilev DI, Vayndorf EM, Wu J, Zhu J, Zhu S, Mason CE, International MetaSUB Consortium, Bezdan D, Ca?as AM, Desnues C, Dias-Neto E, Labaj PP, Moraes MO, Noushmehr H, Ossowski S, ?zcan O, Rascovan N, R?tsch G, Velavan TP, Zambrano MM. A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell. 2021 06 24; 184(13):3376-3393.e17. PMID: 34043940; PMCID: PMC8238498.
      Citations: 78     Fields:    Translation:Humans
    35. Schultze H, Shastry KL, Manamohan S, Mukherjee S, Garg V, Sarveswara R, Pickkers P, Ktena S, Tran F, Herr C, Petersheim D, Behrends U, Schommers P, Lehmann C, Augustin M, Rybniker J, Mishra N, Bernardes JP, Siever C, Desai M, Monnet B, Saridaki M, Siegel CM, Schreiber S, Kim-Hellmuth S, COVID-19 Aachen Study (COVAS), Nattermann J, Skowasch D, Kurth I, Bals R, Rosenstiel P, Netea MG, Theis F, Deutsche COVID-19 Omics Initiative (DeCOI), Giamarellos-Bourboulis EJ, Kox M, Cheran S, Woodacre MS, Goh EL, Warnat-Herresthal S, H?ndler K, Aziz NA, Bitzer M, Ossowski S, Casadei N, Kern F, Fehlmann T, Altm?ller J, Kr?mer B, Bonaguro L, Schulte-Schrepping J, De Domenico E, Kraut M, Drews A, Nuesch-Germano M, Theis H, Heyckendorf J, Keller A, N?rnberg P, Rie? O, Mukherjee S, Backes M, Aschenbrenner AC, Ulas T, Breteler MMB, Becker M, Schultze JL. Swarm Learning for decentralized and confidential clinical machine learning. Nature. 2021 06; 594(7862):265-270. PMID: 34040261; PMCID: PMC8189907.
      Citations: 107     Fields:    Translation:HumansCellsPHPublic Health
    36. Dyack S, MacKay SB, Schatz U, Fleger M, Kurringer A, Balousha G, Ghanim Z, Alkuraya FS, Alzaidan H, Alsaif HS, Mitani T, Bozdogan S, Pehlivan D, Lupski JR, Gleeson JJ, Dehghani M, Mehrjardi MYV, Sherr EH, Parks KC, Argilli E, Begtrup A, Galehdari H, Balousha O, Shariati G, Mazaheri N, Malamiri RA, Pagnamenta AT, Kingston H, Banka S, Jackson A, Osmond M, Care4Rare Canada Consortium, Genomics England Research Consortium, Houlden H, Maroofian R, Hengel H, Hannan SB, Rie? A, Haack TB, N?gele T, Schuster S, Hauser S, Admard J, Casadei N, Velic A, Macek B, Ossowski S, Sch?ls L. Bi-allelic loss-of-function variants in BCAS3 cause a syndromic neurodevelopmental disorder. Am J Hum Genet. 2021 06 03; 108(6):1069-1082. PMID: 34022130; PMCID: PMC8206390.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    37. Urbizu A, Garrett ME, Soldano K, Drechsel O, Loth D, Ossowski S, Macaya A, Loth F, Labuda R, Ashley-Koch A, Marc?-Grau A, Mestres I Soler O, Poca MA. Rare functional genetic variants in COL7A1, COL6A5, COL1A2 and COL5A2 frequently occur in Chiari Malformation Type 1. PLoS One. 2021; 16(5):e0251289. PMID: 33974636; PMCID: PMC8112708.
      Citations: 8     Fields:    Translation:Humans
    38. Espeso-Gil S, Holik AZ, Bonnin S, Jhanwar S, Chandrasekaran S, Pique-Regi R, Maher M, Permanyer J, Irimia M, Pons-Espinal M, Akbarian S, Dierssen M, Maass PG, Hor CN, Ossowski S, Albaig?s-R?fols J, Friedl?nder MR. Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition. Front Mol Neurosci. 2021; 14:664912. PMID: 34025350; PMCID: PMC8131874.
      Citations: 5     
    39. Susak H, Serra-Saurina L, Demidov G, Rabionet R, Bosio M, Muyas F, Estivill X, Ossowski S, Dom?nech L, Escaram?s G. Efficient and flexible Integration of variant characteristics in rare variant association studies using integrated nested Laplace approximation. PLoS Comput Biol. 2021 02; 17(2):e1007784. PMID: 33606672; PMCID: PMC7928502.
      Citations: 2     Fields:    Translation:Humans
    40. Di Genova A, Buena-Atienza E, Ossowski S, Sagot MF. Efficient hybrid de novo assembly of human genomes with WENGAN. Nat Biotechnol. 2021 04; 39(4):422-430. PMID: 33318652; PMCID: PMC8041623.
      Citations: 30     Fields:    Translation:Humans
    41. Bezdan D, Grigorev K, Meydan C, Pelissier Vatter FA, Cioffi M, Rao V, MacKay M, Nakahira K, Burnham P, Afshinnekoo E, Westover C, Butler D, Mozsary C, Donahoe T, Foox J, Mishra T, Lucotti S, Rana BK, Melnick AM, Zhang H, Matei I, Kelsen D, Yu K, Lyden DC, Taylor L, Bailey SM, Snyder MP, Garrett-Bakelman FE, De Vlaminck I, Mason CE, Ossowski S. Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers. iScience. 2020 Dec 18; 23(12):101844. PMID: 33376973; PMCID: PMC7756145.
      Citations: 15     
    42. Tarbier M, Mackowiak SD, Catuara-Solarz S, Biryukova I, Gelali E, Zapata L, Ossowski S, Bienko M, Gallant CJ, Frade J, Men?ndez DB, Friedl?nder MR. Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells. Nat Commun. 2020 10 28; 11(1):5445. PMID: 33116115; PMCID: PMC7595044.
      Citations: 11     Fields:    Translation:AnimalsCells
    43. Schuster S, Heuten E, Velic A, Admard J, Synofzik M, Ossowski S, Macek B, Hauser S, Sch?ls L. CHIP mutations affect the heat shock response differently in human fibroblasts and iPSC-derived neurons. Dis Model Mech. 2020 10 12; 13(10). PMID: 33097556; PMCID: PMC7578354.
      Citations: 5     Fields:    Translation:HumansCells
    44. Hauser S, Schuster S, Heuten E, H?flinger P, Admard J, Schelling Y, Velic A, Macek B, Ossowski S, Sch?ls L. Comparative Transcriptional Profiling of Motor Neuron Disorder-Associated Genes in Various Human Cell Culture Models. Front Cell Dev Biol. 2020; 8:544043. PMID: 33072739; PMCID: PMC7543453.
      Citations: 7     
    45. Hilke FJ, Sinnberg T, Gschwind A, Niessner H, Demidov G, Amaral T, Ossowski S, Bonzheim I, R?cken M, Riess O, Garbe C, Schroeder C, Forschner A. Distinct Mutation Patterns Reveal Melanoma Subtypes and Influence Immunotherapy Response in Advanced Melanoma Patients. Cancers (Basel). 2020 Aug 20; 12(9). PMID: 32825510; PMCID: PMC7563780.
      Citations: 18     
    46. Bosio M, Bezdan D, Gutierrez J, Gut I, Gut M, Ossowski S, Peter S, Gross C, Oberhettinger P, Liese J, Vogel W, D?rfel D, Berger L, Marschal M, Willmann M, Autenrieth I. Tracking of Antibiotic Resistance Transfer and Rapid Plasmid Evolution in a Hospital Setting by Nanopore Sequencing. mSphere. 2020 08 19; 5(4). PMID: 32817379; PMCID: PMC7440845.
      Citations: 35     Fields:    Translation:HumansCells
    47. Hilke FJ, Muyas F, Admard J, Kootz B, Nann D, Welz S, Rie? O, Zips D, Ossowski S, Schroeder C, Clasen K. Dynamics of cell-free tumour DNA correlate with treatment response of head and neck cancer patients receiving radiochemotherapy. Radiother Oncol. 2020 10; 151:182-189. PMID: 32687856.
      Citations: 19     Fields:    Translation:Humans
    48. Zapata L, Muyas F, Guig? R, Ossowski S. The rate and spectrum of mosaic mutations during embryogenesis revealed by RNA sequencing of 49 tissues. Genome Med. 2020 05 27; 12(1):49. PMID: 32460841; PMCID: PMC7254727.
      Citations: 10     Fields:    Translation:Humans
    49. Oberhettinger P, Marschal M, Bezdan D, Ossowski S, Vogel W, Rossen JW, Willmann M, Peter S, Sch?le L, D?rfel D. Description of Citrobacter cronae sp. nov., isolated from human rectal swabs and stool samples. Int J Syst Evol Microbiol. 2020 May; 70(5):2998-3003. PMID: 32375941; PMCID: PMC7395625.
      Citations: 9     Fields:    Translation:HumansCells
    50. Clasen K, Leibfarth S, Hilke FJ, Admard J, Winter RM, Welz S, Gatidis S, Nann D, Ossowski S, Breuer T, la Foug?re C, Nikolaou K, Riess O, Zips D, Schroeder C, Thorwarth D. PET/MRI and genetic intrapatient heterogeneity in head and neck cancers. Strahlenther Onkol. 2020 Jun; 196(6):542-551. PMID: 32211941.
      Citations: 5     Fields:    Translation:Humans
    51. Martus P, Klumpp B, Forschner A, Hilke FJ, Bonzheim I, Gschwind A, Demidov G, Amaral T, Ossowski S, Riess O, Schroeder C, Gonzalez-Menendez I, Garbe C, Niessner H, Sinnberg T. MDM2, MDM4 and EGFR Amplifications and Hyperprogression in Metastatic Acral and Mucosal Melanoma. Cancers (Basel). 2020 Feb 26; 12(3). PMID: 32110946; PMCID: PMC7139387.
      Citations: 31     
    52. Garcia-Prat M, Drechsel O, Ossowski S, Alonso L, Colobran R, Franco-Jarava C, Arcas-Garc?a A, Magall?n-Lorenz M, Mart?n-Nalda A, Rivi?re JG, Soler-Palac?n P, Say?s J, Mart?nez-Gallo M. The IL-2RG R328X nonsense mutation allows partial STAT-5 phosphorylation and defines a critical region involved in the leaky-SCID phenotype. Clin Exp Immunol. 2020 04; 200(1):61-72. PMID: 31799703; PMCID: PMC7066387.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    53. Lohmann E, Hoischen A, Pogoda M, Hilke FJ, Sturm M, Lenz F, Matthes J, Muyas F, Ossowski S, Faust U, Sepahi I, Casadei N, Poths S, Riess O, Schroeder C, Grundmann K. Single Molecule Molecular Inversion Probes for High Throughput Germline Screenings in Dystonia. Front Neurol. 2019; 10:1332. PMID: 31920950; PMCID: PMC6930228.
      Citations: 1     
    54. Moyers JT, Liu LW, Ossowski S, Goddard L, Kamal MO, Cao H. A rash in a hairy situation: Leukocytoclastic vasculitis at presentation of hairy cell Leukemia. Am J Hematol. 2019 12; 94(12):1433-1434. PMID: 31364185.
      Citations: 2     Fields:    Translation:Humans
    55. Susak H, Auber B, Sutter C, Arnold N, Hahnen E, Wang-Gorke S, Weber BHF, Engel C, Lemke JR, Hartkopf A, Nguyen HP, Sepahi I, Faust U, Sturm M, Bosse K, Kehrer M, Heinrich T, Grundman-Hauser K, Bauer P, Ossowski S, Varon R, Schr?ck E, Niederacher D, Dworniczak B, Gehrig A, Riess O, Schroeder C. Investigating the effects of additional truncating variants in DNA-repair genes on breast cancer risk in BRCA1-positive women. BMC Cancer. 2019 Aug 08; 19(1):787. PMID: 31395037; PMCID: PMC6686546.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    56. Zwirner K, Hilke FJ, Demidov G, Socarras Fernandez J, Ossowski S, Gani C, Thorwarth D, Riess O, Zips D, Schroeder C, Welz S. Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D. Strahlenther Onkol. 2019 Sep; 195(9):771-779. PMID: 31123786.
      Citations: 18     Fields:    Translation:Humans
    57. Bosio M, Drechsel O, Rahman R, Muyas F, Rabionet R, Bezdan D, Domenech Salgado L, Hor H, Schott JJ, Munell F, Colobran R, Macaya A, Estivill X, Ossowski S. eDiVA-Classification and prioritization of pathogenic variants for clinical diagnostics. Hum Mutat. 2019 07; 40(7):865-878. PMID: 31026367; PMCID: PMC6767450.
      Citations: 12     Fields:    Translation:Humans
    58. Rabionet R, Alcobendas R, Iglesias E, Modesto C, Puig A, Drechsel O, Ossowski S, Merino R, Estivill X, Remesal A, Mensa-Vilar? A, Mur?as S, Gonz?lez-Roca E, Ruiz-Ortiz E, Ant?n J, Comas D, Yag?e J, Arostegui JI. Biallelic loss-of-function LACC1/FAMIN Mutations Presenting as Rheumatoid Factor-Negative Polyarticular Juvenile Idiopathic Arthritis. Sci Rep. 2019 03 14; 9(1):4579. PMID: 30872671; PMCID: PMC6418186.
      Citations: 11     Fields:    Translation:Humans
    59. Muyas F, Bosio M, Puig A, Susak H, Escaramis G, Zapata L, Demidov G, Estivill X, Rabionet R, Ossowski S, Dom?nech L. Allele balance bias identifies systematic genotyping errors and false disease associations. Hum Mutat. 2019 01; 40(1):115-126. PMID: 30353964; PMCID: PMC6587442.
      Citations: 12     Fields:    Translation:Humans
    60. Franco-Jarava C, Plaja A, Bezdan D, Bosio M, Ossowski S, Colobran R, Soler-Palac?n P, Garcia-Prat M, Mart?n-Nalda A, Rivi?re JG, Mart?nez-Gallo M. LRBA Deficiency in a Patient With a Novel Homozygous Mutation Due to Chromosome 4 Segmental Uniparental Isodisomy. Front Immunol. 2018; 9:2397. PMID: 30386343; PMCID: PMC6198091.
      Citations: 15     Fields:    Translation:HumansCells
    61. Dmitrijeva M, Ossowski S, Serrano L, Schaefer MH. Tissue-specific DNA methylation loss during ageing and carcinogenesis is linked to chromosome structure, replication timing and cell division rates. Nucleic Acids Res. 2018 08 21; 46(14):7022-7039. PMID: 29893918; PMCID: PMC6101545.
      Citations: 17     Fields:    Translation:HumansCells
    62. Zwirner K, Hilke FJ, Demidov G, Ossowski S, Gani C, Rie? O, Zips D, Welz S, Schroeder C. Circulating cell-free DNA: A potential biomarker to differentiate inflammation and infection during radiochemotherapy. Radiother Oncol. 2018 12; 129(3):575-581. PMID: 30097252.
      Citations: 7     Fields:    Translation:Humans
    63. Zapata L, Pich O, Serrano L, Kondrashov FA, Ossowski S, Schaefer MH. Negative selection in tumor genome evolution acts on essential cellular functions and the immunopeptidome. Genome Biol. 2018 05 31; 19(1):67. PMID: 29855388; PMCID: PMC5984361.
      Citations: 40     Fields:    Translation:Humans
    64. Bezdan D, Ossowski S, Peter S, Oberhettinger P, Vogel W, D?rfel D, Dick J, Marschal M, Liese J, Weidenmaier C, Autenrieth I, Willmann M. Whole-genome sequencing enabling the detection of a colistin-resistant hypermutating Citrobacter werkmanii strain harbouring a novel metallo-?-lactamase VIM-48. Int J Antimicrob Agents. 2018 Jun; 51(6):867-874. PMID: 29412174.
      Citations: 7     Fields:    Translation:HumansCells
    65. Bezdan D, Ossowski S, Peter S, Oberhettinger P, Schuele L, Dinkelacker A, Vogel W, D?rfel D, Marschal M, Liese J, Willmann M. Genomic characterisation of clinical and environmental Pseudomonas putida group strains and determination of their role in the transfer of antimicrobial resistance genes to Pseudomonas aeruginosa. BMC Genomics. 2017 Nov 10; 18(1):859. PMID: 29126393; PMCID: PMC5681832.
      Citations: 21     Fields:    Translation:HumansCells
    66. Zapata L, Susak H, Drechsel O, Estivill X, Ossowski S, Friedl?nder MR. Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes. Sci Rep. 2017 10 13; 7(1):13124. PMID: 29030609; PMCID: PMC5640613.
      Citations: 14     Fields:    Translation:HumansCells
    67. Wambach JA, Writzl K, Munell F, Bosio M, Wegner DJ, Shinawi M, Baldridge D, Grange DK, Troxell R, Collins J, Warner BB, Schmidt RE, Pestronk A, Cole FS, Stettner GM, Haack TB, ?kofljanec A, Maver A, Ossowski S, Alhaddad B, Strom TM, Wilichowski E, Steinfeld R. Survival among children with "Lethal" congenital contracture syndrome 11 caused by novel mutations in the gliomedin gene (GLDN). Hum Mutat. 2017 11; 38(11):1477-1484. PMID: 28726266; PMCID: PMC5638693.
      Citations: 7     Fields:    Translation:Humans
    68. Urreizti R, Cueto-Gonzalez AM, Roca-Ayats N, Ponomarenko J, Cozzuto L, Company C, Bosio M, Ossowski S, Montfort M, Hecht J, Tizzano EF, Cormand B, Opitz JM, Grinberg D, Balcells S, Franco-Valls H, Mort-Farre S, Vilageliu L, Neri G. A De Novo Nonsense Mutation in MAGEL2 in a Patient Initially Diagnosed as Opitz-C: Similarities Between Schaaf-Yang and Opitz-C Syndromes. Sci Rep. 2017 03 10; 7:44138. PMID: 28281571; PMCID: PMC5345063.
      Citations: 17     Fields:    Translation:Humans
    69. Mohrman AE, Farrag M, Huang H, Ossowski S, Haft S, Shriver LP, Leipzig ND. Spinal Cord Transcriptomic and Metabolomic Analysis after Excitotoxic Injection Injury Model of Syringomyelia. J Neurotrauma. 2017 02; 34(3):720-733. PMID: 27736311.
      Citations: 10     Fields:    Translation:AnimalsCells
    70. Hassan AE, Ossowski SE, Malik AA, Sanchez C, Abantao E, Sanchez O, Tekle WG, Qureshi AI. Does Hospitalist Directed Care for Acute Ischemic Stroke Patients Improve Adherence to "Get with the Guidelines"? J Vasc Interv Neurol. 2016 Oct; 9(2):30-33. PMID: 27829968; PMCID: PMC5094258.
      Citations: 2     
    71. De Toma I, Manubens-Gil L, Ossowski S, Dierssen M. Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders. Neural Plast. 2016; 2016:4235898. PMID: 27547454; PMCID: PMC4980517.
      Citations: 9     Fields:    Translation:HumansCells
    72. Zapata L, Ding J, Willing EM, Hartwig B, Bezdan D, Jiao WB, Patel V, Velikkakam James G, Koornneef M, Ossowski S, Schneeberger K. Chromosome-level assembly of Arabidopsis thaliana Ler reveals the extent of translocation and inversion polymorphisms. Proc Natl Acad Sci U S A. 2016 07 12; 113(28):E4052-60. PMID: 27354520; PMCID: PMC4948326.
      Citations: 102     Fields:    Translation:AnimalsCells
    73. Prasad A, Rabionet R, Espinet B, Zapata L, Puiggros A, Melero C, Puig A, Sarria-Trujillo Y, Ossowski S, Garcia-Muret MP, Estrach T, Servitje O, Lopez-Lerma I, Gallardo F, Pujol RM, Estivill X. Identification of Gene Mutations and Fusion Genes in Patients with S?zary Syndrome. J Invest Dermatol. 2016 07; 136(7):1490-1499. PMID: 27039262.
      Citations: 45     Fields:    Translation:HumansCells
    74. Drechsel O, Rahman R, Ossowski S, Bahamonde MI, Serra SA, Marc?-Grau A, Prieto M, Macaya A, Fern?ndez-Fern?ndez JM. A Single Amino Acid Deletion (?F1502) in the S6 Segment of CaV2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca2+ Influx. PLoS One. 2015; 10(12):e0146035. PMID: 26716990; PMCID: PMC4696675.
      Citations: 17     Fields:    Translation:Humans
    75. Sorge S, Ha N, Polychronidou M, Friedrich J, Bezdan D, Kaspar P, Schaefer MH, Ossowski S, Henz SR, Mundorf J, Papagiannouli F, Lohmann I, R?tzer J. The cis-regulatory code of Hox function in Drosophila. EMBO J. 2015 Nov 12; 34(22):2862. PMID: 26564906; PMCID: PMC4682644.
      Citations: 1     Fields:    
    76. Casacuberta JM, Ossowski S, H?naff E, Zapata L. Jitterbug: somatic and germline transposon insertion detection at single-nucleotide resolution. BMC Genomics. 2015 Oct 12; 16:768. PMID: 26459856; PMCID: PMC4603299.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    77. Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Milan DJ, Norris RA, Slaugenhaupt SA, Perrocheau M, LeMarec H, Bruneval P, Levine RA. Mutations in DCHS1 cause mitral valve prolapse. Nature. 2015 Sep 03; 525(7567):109-13. PMID: 26258302; PMCID: PMC4720389.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    78. Francescatto L, Bartesaghi L, Kousi M, Gironell A, Drechsel O, Kenzelmann Broz D, Chiquet-Ehrismann R, Coria F, Alonso-Navarro H, Ossowski S, Chrast R, Katsanis N, Hor H, Ortega-Cubero S, Lorenzo-Betancor O, Jim?nez-Jim?nez FJ, Clarim?n J, Ag?ndez JA, Lle? A, Garc?a-Martin E, Mart? MJ, Kulisevsky J, Hor CN, Pastor P, Estivill X. Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor. Hum Mol Genet. 2015 Oct 15; 24(20):5677-86. PMID: 26188006; PMCID: PMC4692992.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    79. Bassaganyas L, Tornador C, Salaverria I, Zapata L, Drechsel O, Ferreira PG, Rodriguez-Santiago B, Tubio JM, Navarro A, Gut M, Ossowski S, Campo E, Estivill X, Be? S, Escaram?s G, Mart?n-Garc?a D, L?pez C, Mart?nez-Trillos A, L?pez-Guillermo A, L?pez-Ot?n C. Sporadic and reversible chromothripsis in chronic lymphocytic leukemia revealed by longitudinal genomic analysis. Leukemia. 2015 Mar; 29(3):758. PMID: 25738466; PMCID: PMC5780638.
      Citations: 2     Fields:    
    80. Di Vona C, Bezdan D, Islam AB, Ossowski S, Salichs E, L?pez-Bigas N, de la Luna S. Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase. Mol Cell. 2015 Feb 05; 57(3):506-20. PMID: 25620562.
      Citations: 67     Fields:    Translation:HumansCells
    81. Bezdan D, Zapata L, Susak H, Ossowski S, Willmann M, Vogel W, Schr?ppel K, Liese J, Weidenmaier C, Autenrieth IB, Peter S. Analysis of a long-term outbreak of XDR Pseudomonas aeruginosa: a molecular epidemiological study. J Antimicrob Chemother. 2015 May; 70(5):1322-30. PMID: 25583750.
      Citations: 22     Fields:    Translation:HumansCellsPHPublic Health
    82. Chae E, Bomblies K, Kim ST, Karelina D, Zaidem M, Ossowski S, Mart?n-Pizarro C, Laitinen RA, Rowan BA, Tenenboim H, Lechner S, Demar M, Habring-M?ller A, Lanz C, R?tsch G, Weigel D. Species-wide genetic incompatibility analysis identifies immune genes as hot spots of deleterious epistasis. Cell. 2014 Dec 04; 159(6):1341-51. PMID: 25467443; PMCID: PMC4269942.
      Citations: 102     Fields:    Translation:AnimalsCells
    83. Trujillano D, Ossowski S, Fraga G, Ariceta G, Estivill X, Bullich G, Sant?n S, Mendiz?bal S, Madrid ?, Ballar?n J, Torra R, Ars E. Targeted next-generation sequencing in steroid-resistant nephrotic syndrome: mutations in multiple glomerular genes may influence disease severity. Eur J Hum Genet. 2015 Sep; 23(9):1192-9. PMID: 25407002; PMCID: PMC4538209.
      Citations: 42     Fields:    Translation:Humans
    84. Zee PC, Mendes-Soares H, Yu YT, Kraemer SA, Keller H, Ossowski S, Schneeberger K, Velicer GJ. A shift from magnitude to sign epistasis during adaptive evolution of a bacterial social trait. Evolution. 2014 09; 68(9):2701-8. PMID: 24909926.
      Citations: 7     Fields:    Translation:Cells
    85. Altucci L, Amati B, Ashley N, Baulcombe D, Beaujean N, Bock C, Bongcam-Rudloff E, Bousquet J, Braun S, Bressac-de Paillerets B, Bussemakers M, Clarke L, Conesa A, Estivill X, Fazeli A, Gut I, Heijmans BT, Hermouet S, Houwing-Duistermaat J, Iacobucci I, Kandimalla R, Krauss-Etschmann S, Lasko P, Lindroth A, Majdic G, Marcotte E, Martinelli G, Martinet N, Meyer E, Miceli C, Mills K, Moreno-Villanueva M, Morvan G, Niesler B, Nowacki M, Nowak J, Ossowski S, Pelizzola M, Pochet R, Radwanska M, Raes J, Rattray M, Robinson MD, Roelen B, Sauer S, Schinzer D, Slagboom E, Spector T, Stunnenberg HG, Tiligada E, Torres-Padilla ME, Tsonaka R, Van Soom A, Vidakovic M, Widschwendter M, Almouzni G, Grgurevic N, Ila? J, Lehmann S, Nickel D, Potocnik U. Relationship between genome and epigenome--challenges and requirements for future research. BMC Genomics. 2014 Jun 18; 15:487. PMID: 24942464; PMCID: PMC4073504.
      Citations: 14     Fields:    Translation:Humans
    86. Ossowski S, Trujillano D, Bullich G, Ballar?n J, Torra R, Estivill X, Ars E. Diagnosis of autosomal dominant polycystic kidney disease using efficient PKD1 and PKD2 targeted next-generation sequencing. Mol Genet Genomic Med. 2014 Sep; 2(5):412-21. PMID: 25333066; PMCID: PMC4190876.
      Citations: 33     Fields:    
    87. Wijnker E, Velikkakam James G, Ding J, Becker F, Klasen JR, Rawat V, Rowan BA, de Snoo CB, Zapata L, Huettel B, de Jong H, Ossowski S, Weigel D, Koornneef M, Keurentjes JJ, Schneeberger K, de Jong DF. The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana. Elife. 2013 Dec 17; 2:e01426. PMID: 24347547; PMCID: PMC3865688.
      Citations: 117     Fields:    Translation:Animals
    88. Hauser F, Chen W, Deinlein U, Chang K, Ossowski S, Fitz J, Hannon GJ, Schroeder JI. A genomic-scale artificial microRNA library as a tool to investigate the functionally redundant gene space in Arabidopsis. Plant Cell. 2013 Aug; 25(8):2848-63. PMID: 23956262; PMCID: PMC3784584.
      Citations: 31     Fields:    Translation:Animals
    89. Trujillano D, Tornador C, Escaramis G, Ossowski S, Estivill X, Perez B, Gonz?lez J, Navarrete R, Armengol L, Cornejo V, Desviat LR, Ugarte M. Accurate molecular diagnosis of phenylketonuria and tetrahydrobiopterin-deficient hyperphenylalaninemias using high-throughput targeted sequencing. Eur J Hum Genet. 2014 Apr; 22(4):528-34. PMID: 23942198; PMCID: PMC3953903.
      Citations: 21     Fields:    Translation:Humans
    90. Ramos MD, Trujillano D, Olivar R, Sotillo F, Ossowski S, Manzanares J, Costa J, Gartner S, Oliva C, Quintana E, Gonzalez MI, Vazquez C, Estivill X, Casals T. Extensive sequence analysis of CFTR, SCNN1A, SCNN1B, SCNN1G and SERPINA1 suggests an oligogenic basis for cystic fibrosis-like phenotypes. Clin Genet. 2014 Jul; 86(1):91-5. PMID: 23837941.
      Citations: 7     Fields:    Translation:HumansCells
    91. Koenig D, Kimura S, Fulop D, Chitwood DH, Headland LR, Kumar R, Covington MF, Devisetty UK, Tat AV, Tohge T, Bolger A, Schneeberger K, Ossowski S, Lanz C, Xiong G, Taylor-Teeples M, Brady SM, Pauly M, Weigel D, Fernie AR, Peng J, Sinha NR, Maloof JN, Jim?nez-G?mez JM, Usadel B. Comparative transcriptomics reveals patterns of selection in domesticated and wild tomato. Proc Natl Acad Sci U S A. 2013 Jul 09; 110(28):E2655-62. PMID: 23803858; PMCID: PMC3710864.
      Citations: 153     Fields:    Translation:AnimalsCells
    92. Tornador C, Bassaganyas L, Rabionet R, Tubio JM, Gut M, Ossowski S, Estivill X, Escaram?s G, Mart?nez-Fundichely A, C?ceres M. PeSV-Fisher: identification of somatic and non-somatic structural variants using next generation sequencing data. PLoS One. 2013; 8(5):e63377. PMID: 23704902; PMCID: PMC3660373.
      Citations: 9     Fields:    Translation:Humans
    93. Trujillano D, Ramos MD, Tornador C, Sotillo F, Escaramis G, Ossowski S, Armengol L, Casals T, Estivill X, Gonz?lez J. Next generation diagnostics of cystic fibrosis and CFTR-related disorders by targeted multiplex high-coverage resequencing of CFTR. J Med Genet. 2013 Jul; 50(7):455-62. PMID: 23687349.
      Citations: 17     Fields:    Translation:HumansCells
    94. Tornador C, Salaverria I, Zapata L, Drechsel O, Ferreira PG, Rodriguez-Santiago B, Tubio JM, Navarro A, Gut M, Ossowski S, Campo E, Estivill X, Bassaganyas L, Be? S, Escaram?s G, Mart?n-Garc?a D, L?pez C, Mart?nez-Trillos A, L?pez-Guillermo A, L?pez-Ot?n C. Sporadic and reversible chromothripsis in chronic lymphocytic leukemia revealed by longitudinal genomic analysis. Leukemia. 2013 Dec; 27(12):2376-9. PMID: 23612016; PMCID: PMC3865532.
      Citations: 14     Fields:    Translation:HumansCells
    95. Ossowski S, Schwab R, Weigel D, Warthmann N. Artificial microRNAs for specific gene silencing in rice. Methods Mol Biol. 2013; 956:131-49. PMID: 23135850.
      Citations: 2     Fields:    Translation:Animals
    96. Kopischke M, Westphal L, Schneeberger K, Clark R, Ossowski S, Wewer V, Hause G, Lipka V, Weigel D, Schulze-Lefert P, Scheel D, Rosahl S, Fuchs R, Landtag J, D?rmann P. Impaired sterol ester synthesis alters the response of Arabidopsis thaliana to Phytophthora infestans. Plant J. 2013 Feb; 73(3):456-68. PMID: 23072470.
      Citations: 23     Fields:    Translation:AnimalsCells
    97. Paschold A, Jia Y, Marcon C, Lund S, Larson NB, Yeh CT, Ossowski S, Lanz C, Nettleton D, Schnable PS, Hochholdinger F. Complementation contributes to transcriptome complexity in maize (Zea mays L.) hybrids relative to their inbred parents. Genome Res. 2012 Dec; 22(12):2445-54. PMID: 23086286; PMCID: PMC3514674.
      Citations: 75     Fields:    Translation:AnimalsCells
    98. Sorge S, Ha N, Polychronidou M, Friedrich J, Bezdan D, Kaspar P, Schaefer MH, Ossowski S, Henz SR, Mundorf J, Papagiannouli F, Lohmann I, R?tzer J. The cis-regulatory code of Hox function in Drosophila. EMBO J. 2012 Aug 01; 31(15):3323-33. PMID: 22781127; PMCID: PMC3411081.
      Citations: 26     Fields:    Translation:AnimalsCells
    99. Barc J, Trujillano D, Bouatia-Naji N, Pylypenko O, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Chabre O, Delahousse M, Esnault V, Houillier P, Bagnis CI, Koenig J, Konrad M, Landais P, Mourani C, Niaudet P, Probst V, Thauvin C, Unwin RJ, Soroka SD, Ehret G, Ossowski S, Caulfield M, International Consortium for Blood Pressure (ICBP), Bruneval P, Estivill X, Froguel P, Hadchouel J, Schott JJ, Jeunemaitre X, Louis-Dit-Picard H, Miserey-Lenkei S, Beaurain G, Bonnefond A, Broux F, Fiquet B. KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron. Nat Genet. 2012 Mar 11; 44(4):456-60, S1-3. PMID: 22406640.
      Citations: 143     Fields:    Translation:HumansCells
    100. Rutter MT, Roles A, Conner JK, Shaw RG, Shaw FH, Schneeberger K, Ossowski S, Weigel D, Fenster CB. Fitness of Arabidopsis thaliana mutation accumulation lines whose spontaneous mutations are known. Evolution. 2012 Jul; 66(7):2335-9. PMID: 22759306.
      Citations: 22     Fields:    Translation:Animals
    101. Schneeberger K, Ossowski S, Bender S, Fitz J, Koenig D, Lanz C, Stegle O, Lippert C, Wang X, Ott F, Alonso-Blanco C, Borgwardt K, Schmid KJ, Weigel D, Cao J, G?nther T, M?ller J. Whole-genome sequencing of multiple Arabidopsis thaliana populations. Nat Genet. 2011 Aug 28; 43(10):956-63. PMID: 21874002.
      Citations: 471     Fields:    Translation:AnimalsCells
    102. Ossowski S, Schneeberger K, Weigel D, Huson DH, Klein JD. LOCAS--a low coverage assembly tool for resequencing projects. PLoS One. 2011; 6(8):e23455. PMID: 21858125; PMCID: PMC3156226.
      Citations: 12     Fields:    Translation:AnimalsCells
    103. Guo YL, Fitz J, Schneeberger K, Ossowski S, Cao J, Weigel D. Genome-wide comparison of nucleotide-binding site-leucine-rich repeat-encoding genes in Arabidopsis. Plant Physiol. 2011 Oct; 157(2):757-69. PMID: 21810963; PMCID: PMC3192553.
      Citations: 89     Fields:    Translation:AnimalsCells
    104. Ossowski S, Ott F, Klein JD, Wang X, Lanz C, Smith LM, Cao J, Fitz J, Warthmann N, Henz SR, Huson DH, Weigel D, Schneeberger K. Reference-guided assembly of four diverse Arabidopsis thaliana genomes. Proc Natl Acad Sci U S A. 2011 Jun 21; 108(25):10249-54. PMID: 21646520; PMCID: PMC3121819.
      Citations: 124     Fields:    Translation:AnimalsCells
    105. Hu TT, Pattyn P, Bakker EG, Cao J, Cheng JF, Clark RM, Fahlgren N, Fawcett JA, Grimwood J, Gundlach H, Haberer G, Hollister JD, Ossowski S, Ottilar RP, Salamov AA, Schneeberger K, Spannagl M, Wang X, Yang L, Nasrallah ME, Bergelson J, Carrington JC, Gaut BS, Schmutz J, Mayer KF, Van de Peer Y, Grigoriev IV, Nordborg M, Weigel D, Guo YL. The Arabidopsis lyrata genome sequence and the basis of rapid genome size change. Nat Genet. 2011 May; 43(5):476-81. PMID: 21478890; PMCID: PMC3083492.
      Citations: 399     Fields:    Translation:AnimalsCells
    106. Bailey CD, Cartolano M, Krieger J, Cao J, Ossowski S, Schneeberger K, He F, de Meaux J, Hall N, Macleod N, Filatov D, Hay A, Tsiantis M, Piazza P. Arabidopsis thaliana leaf form evolved via loss of KNOX expression in leaves in association with a selective sweep. Curr Biol. 2010 Dec 21; 20(24):2223-8. PMID: 21129970.
      Citations: 36     Fields:    Translation:Animals
    107. Laitinen RA, Schneeberger K, Ossowski S, Weigel D, Jelly NS. Identification of a spontaneous frame shift mutation in a nonreference Arabidopsis accession using whole genome sequencing. Plant Physiol. 2010 Jun; 153(2):652-4. PMID: 20388671; PMCID: PMC2879766.
      Citations: 25     Fields:    Translation:Animals
    108. Khraiwesh B, Arif MA, Seumel GI, Ossowski S, Weigel D, Reski R, Frank W. Transcriptional control of gene expression by microRNAs. Cell. 2010 Jan 08; 140(1):111-22. PMID: 20085706.
      Citations: 210     Fields:    Translation:AnimalsCells
    109. Schneeberger K, Warthmann N, Clark RM, Shaw RG, Weigel D, Lynch M, Ossowski S, Lucas-Lled? JI. The rate and molecular spectrum of spontaneous mutations in Arabidopsis thaliana. Science. 2010 Jan 01; 327(5961):92-4. PMID: 20044577; PMCID: PMC3878865.
      Citations: 493     Fields:    Translation:AnimalsCells
    110. Ossowski S, Warthmann N, Weigel D, Schwab R. Directed gene silencing with artificial microRNAs. Methods Mol Biol. 2010; 592:71-88. PMID: 19802590.
      Citations: 24     Fields:    Translation:Animals
    111. Out AA, van Minderhout IJ, Goeman JJ, Ariyurek Y, Ossowski S, Schneeberger K, Weigel D, van Galen M, Taschner PE, Tops CM, Breuning MH, van Ommen GJ, den Dunnen JT, Devilee P, Hes FJ. Deep sequencing to reveal new variants in pooled DNA samples. Hum Mutat. 2009 Dec; 30(12):1703-12. PMID: 19842214.
      Citations: 45     Fields:    Translation:HumansCells
    112. Ossowski S, Warthmann N, Gesing S, Kohlbacher O, Weigel D, Schneeberger K, Hagmann J. Simultaneous alignment of short reads against multiple genomes. Genome Biol. 2009; 10(9):R98. PMID: 19761611; PMCID: PMC2768987.
      Citations: 92     Fields:    Translation:Cells
    113. Mirouze M, Reinders J, Bucher E, Nishimura T, Schneeberger K, Ossowski S, Cao J, Weigel D, Paszkowski J, Mathieu O. Selective epigenetic control of retrotransposition in Arabidopsis. Nature. 2009 Sep 17; 461(7262):427-30. PMID: 19734882.
      Citations: 163     Fields:    Translation:AnimalsCells
    114. Schneeberger K, Ossowski S, Lanz C, Juul T, Weigel D, Petersen AH, Nielsen KL, J?rgensen JE, Andersen SU. SHOREmap: simultaneous mapping and mutation identification by deep sequencing. Nat Methods. 2009 Aug; 6(8):550-1. PMID: 19644454.
      Citations: 298     Fields:    Translation:Animals
    115. Molnar A, Bassett A, Thuenemann E, Schwach F, Karkare S, Ossowski S, Weigel D, Baulcombe D. Highly specific gene silencing by artificial microRNAs in the unicellular alga Chlamydomonas reinhardtii. Plant J. 2009 Apr; 58(1):165-74. PMID: 19054357.
      Citations: 130     Fields:    Translation:AnimalsCells
    116. Schneeberger K, Clark RM, Lanz C, Warthmann N, Weigel D, Ossowski S. Sequencing of natural strains of Arabidopsis thaliana with short reads. Genome Res. 2008 Dec; 18(12):2024-33. PMID: 18818371; PMCID: PMC2593571.
      Citations: 242     Fields:    Translation:AnimalsCells
    117. Khraiwesh B, Ossowski S, Weigel D, Reski R, Frank W. Specific gene silencing by artificial MicroRNAs in Physcomitrella patens: an alternative to targeted gene knockouts. Plant Physiol. 2008 Oct; 148(2):684-93. PMID: 18753280; PMCID: PMC2556843.
      Citations: 36     Fields:    Translation:AnimalsCells
    118. Ossowski S, Schneeberger K, De Bona F, R?tsch G. Optimal spliced alignments of short sequence reads. Bioinformatics. 2008 Aug 15; 24(16):i174-80. PMID: 18689821.
      Citations: 53     Fields:    Translation:Cells
    119. Chen H, Ossowski S, Weigel D, Warthmann N, Herv? P. Highly specific gene silencing by artificial miRNAs in rice. PLoS One. 2008 Mar 19; 3(3):e1829. PMID: 18350165; PMCID: PMC2262943.
      Citations: 120     Fields:    Translation:AnimalsCells
    120. Schwab R, Weigel D, Ossowski S. Gene silencing in plants using artificial microRNAs and other small RNAs. Plant J. 2008 Feb; 53(4):674-90. PMID: 18269576.
      Citations: 267     Fields:    Translation:HumansAnimals
    121. Kim S, Plagnol V, Hu TT, Toomajian C, Clark RM, Ossowski S, Ecker JR, Weigel D, Nordborg M. Recombination and linkage disequilibrium in Arabidopsis thaliana. Nat Genet. 2007 Sep; 39(9):1151-5. PMID: 17676040.
      Citations: 251     Fields:    Translation:AnimalsCells
    122. Schweikert G, Toomajian C, Ossowski S, Zeller G, Shinn P, Warthmann N, Hu TT, Fu G, Hinds DA, Chen H, Frazer KA, Huson DH, Nordborg M, Ecker JR, Weigel D, Clark RM, Sch?lkopf B, R?tsch G. Common sequence polymorphisms shaping genetic diversity in Arabidopsis thaliana. Science. 2007 Jul 20; 317(5836):338-42. PMID: 17641193.
      Citations: 363     Fields:    Translation:AnimalsCells
    123. Lewis J, Ossowski S, Hicks J, Errami M, Garner HR. Text similarity: an alternative way to search MEDLINE. Bioinformatics. 2006 Sep 15; 22(18):2298-304. PMID: 16926219.
      Citations: 25     Fields:    
    124. Ossowski S, Riester M, Warthmann N, Weigel D, Schwab R. Highly specific gene silencing by artificial microRNAs in Arabidopsis. Plant Cell. 2006 May; 18(5):1121-33. PMID: 16531494; PMCID: PMC1456875.
      Citations: 571     Fields:    Translation:AnimalsCells

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