"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
| Descriptor ID |
D035683
|
| MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
|
| Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
|
Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 3 | 0 | 3 |
| 2009 | 3 | 0 | 3 |
| 2010 | 4 | 0 | 4 |
| 2011 | 3 | 1 | 4 |
| 2012 | 4 | 2 | 6 |
| 2013 | 6 | 0 | 6 |
| 2014 | 1 | 0 | 1 |
| 2015 | 5 | 1 | 6 |
| 2016 | 5 | 3 | 8 |
| 2017 | 5 | 1 | 6 |
| 2018 | 3 | 2 | 5 |
| 2019 | 3 | 1 | 4 |
| 2020 | 2 | 2 | 4 |
| 2021 | 2 | 0 | 2 |
| 2022 | 7 | 1 | 8 |
| 2023 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia. Circ Res. 2023 03 31; 132(7):e96-e113.
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Lipid phosphate phosphatase 3 maintains NO-mediated flow-mediated dilatation in human adipose resistance arterioles. J Physiol. 2023 02; 601(3):469-481.
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Genetic and functional analyses implicate microRNA 499A in bipolar disorder development. Transl Psychiatry. 2022 10 07; 12(1):437.
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Differential microRNA expression analyses across two brain regions in Alzheimer's disease. Transl Psychiatry. 2022 08 29; 12(1):352.
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Detailed Transcriptional Landscape of Peripheral Blood Points to Increased Neutrophil Activation in Treatment-Na?ve Inflammatory Bowel Disease. J Crohns Colitis. 2022 Aug 04; 16(7):1097-1109.
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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors. Nat Commun. 2022 07 13; 13(1):4061.
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LINC00152 Drives a Competing Endogenous RNA Network in Human Hepatocellular Carcinoma. Cells. 2022 05 03; 11(9).
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Antiviral RNAi Response against the Insect-Specific Agua Salud Alphavirus. mSphere. 2022 02 23; 7(1):e0100321.
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miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR. Int J Mol Sci. 2022 Feb 14; 23(4).
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Exosomal miRNAs from Prostate Cancer Impair Osteoblast Function in Mice. Int J Mol Sci. 2022 Jan 24; 23(3).
MeSH information
