Next Generation Sequencing Competence Network

Next Generation Sequencing Competence Network

e.g. CCGA
(min 2 characters)

Nicolas Casadei

Dr.
University of Tuebingen
University Hospital Tuebingen (UKT), Institute for Medical Genetics and Applied Genomics (IMGAG)
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Raposo M, H?bener-Schmid J, Ferreira AF, Vieira Melo AR, Vasconcelos J, Pires P, Kay T, Garcia-Moreno H, Giunti P, Santana MM, Pereira de Almeida L, Infante J, van de Warrenburg BP, de Vries JJ, Faber J, Klockgether T, Casadei N, Admard J, Sch?ls L, European Spinocerebellar ataxia type 3/Machado-Joseph disease Initiative (ESMI) study group , Riess O, Lima M, Raposo M, H?bener-Schmid J, Ferreira AF, Vieira Melo AR, Vasconcelos J, Pires P, Kay T, Garcia-Moreno H, Giunti P, Infante J, van de Warrenburg BP, de Vries JJ, Faber J, Klockgether T, Casadei N, Admard J, Sch?ls L, European Spinocerebellar ataxia type 3/Machado-Joseph disease Initiative (ESMI) study group, Riess O, Lima M. Blood transcriptome sequencing identifies biomarkers able to track disease stages in spinocerebellar ataxia type 3. Brain. 2023 10 03; 146(10):4132-4143. PMID: 37071051.
      Citations:    Fields:    Translation:HumansCells
    2. Weisschuh N, Mazzola P, Zuleger T, Schaeferhoff K, K?hlewein L, Kort?m F, Witt D, Liebmann A, Falb R, Pohl L, Reith M, St?hn LG, Bertrand M, M?ller A, Casadei N, Kelemen O, Kelbsch C, Kernstock C, Richter P, Sadler F, Demidov G, Sch?tz L, Admard J, Sturm M, Grasshoff U, Tonagel F, Heinrich T, Nasser F, Wissinger B, Ossowski S, Kohl S, Riess O, Stingl K, Haack TB. Diagnostic genome sequencing improves diagnostic yield: a prospective single-centre study in 1000 patients with inherited eye diseases. J Med Genet. 2023 Sep 21. PMID: 37734845.
      Citations: 3     Fields:    Translation:HumansCells
    3. Reissig TM, Ladigan-Badura S, Steinberg A, Maghnouj A, Li T, Verdoodt B, Liffers ST, Pohl M, Wolters H, Teschendorf C, Viebahn R, Admard J, Casadei N, Tannapfel A, Schmiegel W, Hahn SA, Vangala DB. Lasting response by vertical inhibition with cetuximab and?trametinib in KRAS-mutated colorectal cancer patient-derived xenografts. Mol Oncol. 2023 Aug 21. PMID: 37604687.
      Citations:    Fields:    Translation:Humans
    4. Singh Y, Trautwein C, Romani J, Salker MS, Neckel PH, Fraccaroli I, Abeditashi M, Woerner N, Admard J, Dhariwal A, Dueholm MKD, Sch?fer KH, Lang F, Otzen DE, Lashuel HA, Riess O, Casadei N. Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease. Mol Neurodegener. 2023 07 04; 18(1):44. PMID: 37403161; PMCID: PMC10318726.
      Citations: 4     Fields:    Translation:HumansAnimals
    5. Rodi M, Gross C, Sandri TL, Berner L, Marcet-Houben M, Kocak E, Pogoda M, Casadei N, K?hler C, Kreidenweiss A, Agnandji ST, Gabald?n T, Ossowski S, Held J. Whole genome analysis of two sympatric human Mansonella: Mansonella perstans and Mansonella sp "DEUX". Front Cell Infect Microbiol. 2023; 13:1159814. PMID: 37124042; PMCID: PMC10145164.
      Citations:    Fields:    Translation:HumansAnimalsCells
    6. Li K, Figarella K, Su X, Kovalchuk Y, Gorzolka J, Neher JJ, Mojtahedi N, Casadei N, Hedrich UBS, Garaschuk O. Endogenous but not sensory-driven activity controls migration, morphogenesis and survival of adult-born juxtaglomerular neurons in the mouse olfactory bulb. Cell Mol Life Sci. 2023 Mar 18; 80(4):98. PMID: 36932186; PMCID: PMC10023654.
      Citations: 2     Fields:    Translation:AnimalsCells
    7. Hemmen K, Sch?rg BF, Pogoda M, Hoffmann SHL, Pinnecker J, Singh Y, Mack AF, Pichler B, Lang F, Nieswandt B, Heinze KG, Casadei N, Sch?tte JP, Manke MC, M?nzer P, Ramos GC, Dicenta V, Kollotzek F, Zdanyte M, Mueller KAL, Gawaz M, Borst O. Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia. Circ Res. 2023 03 31; 132(7):e96-e113. PMID: 36891903.
      Citations: 1     Fields:    Translation:AnimalsCells
    8. Witt D, Faust U, Strobl-Wildemann G, Sturm M, Buchert R, Zuleger T, Admard J, Casadei N, Ossowski S, Haack TB, Rie? O, Schroeder C. Genome sequencing identifies complex structural MLH1 variant in unsolved Lynch syndrome. Mol Genet Genomic Med. 2023 06; 11(6):e2151. PMID: 36760167; PMCID: PMC10265068.
      Citations: 2     Fields:    Translation:HumansCells
    9. Schwarz L, Sharma K, Dodi LD, Rieder LS, Fallier-Becker P, Casadei N, Fitzgerald JC. Miro1 R272Q disrupts mitochondrial calcium handling and neurotransmitter uptake in dopaminergic neurons. Front Mol Neurosci. 2022; 15:966209. PMID: 36533136; PMCID: PMC9757607.
      Citations: 2     
    10. Cheng F, Zheng W, Liu C, Barbuti PA, Yu-Taeger L, Casadei N, Huebener-Schmid J, Admard J, Boldt K, Junger K, Ueffing M, Houlden H, Sharma M, Kruger R, Grundmann-Hauser K, Ott T, Riess O. Intronic enhancers of the human SNCA gene predominantly regulate its expression in brain in vivo. Sci Adv. 2022 11 25; 8(47):eabq6324. PMID: 36417521.
      Citations: 1     Fields:    Translation:HumansCells
    11. Cheng F, Zheng W, Barbuti PA, Bonsi P, Casadei N, Ponterio G, Meringolo M, Admard J, Dording CM, Yu-Taeger L, Nguyen HP, Grundmann-Hauser K, Ott T, Houlden H, Pisani A, Riess O, Liu C, Kr?ger R. DYT6 mutated THAP1 is a cell type dependent regulator of the SP1 family. Brain. 2022 11 21; 145(11):3968-3984. PMID: 35015830.
      Citations: 1     Fields:    Translation:HumansAnimals
    12. Ledonne A, Massaro Cenere M, Paldino E, D'Angelo V, D'Addario SL, Casadei N, Nobili A, Berretta N, Fusco FR, Ventura R, Sancesario G, Guatteo E, Mercuri NB. Morpho-Functional Changes of Nigral Dopamine Neurons in an a-Synuclein Model of Parkinson's Disease. Mov Disord. 2023 02; 38(2):256-266. PMID: 36350188.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    13. Butler-Laporte G, Povysil G, Kosmicki JA, Cirulli ET, Drivas T, Furini S, Saad C, Schmidt A, Olszewski P, Korotko U, Quinodoz M, ?elik E, Kundu K, Walter K, Jung J, Stockwell AD, Sloofman LG, Jordan DM, Thompson RC, Del Valle D, Simons N, Cheng E, Sebra R, Schadt EE, Kim-Schulze S, Gnjatic S, Merad M, Buxbaum JD, Beckmann ND, Charney AW, Przychodzen B, Chang T, Pottinger TD, Shang N, Brand F, Fava F, Mari F, Chwialkowska K, Niemira M, Pula S, Baillie JK, Stuckey A, Salas A, Bello X, Pardo-Seco J, G?mez-Carballa A, Rivero-Calle I, Martin?n-Torres F, Ganna A, Karczewski KJ, Veerapen K, Bourgey M, Bourque G, Eveleigh RJ, Forgetta V, Morrison D, Langlais D, Lathrop M, Mooser V, Nakanishi T, Frithiof R, Hultstr?m M, Lipcsey M, Marincevic-Zuniga Y, Nordlund J, Schiabor Barrett KM, Lee W, Bolze A, White S, Riffle S, Tanudjaja F, Sandoval E, Neveux I, Dabe S, Casadei N, Motameny S, Alaamery M, Massadeh S, Aljawini N, Almutairi MS, Arabi YM, Alqahtani SA, Al Harthi FS, Almutairi A, Alqubaishi F, Alotaibi S, Binowayn A, Alsolm EA, El Bardisy H, Fawzy M, Cai F, Soranzo N, Butterworth A, COVID-19 Host Genetics Initiative, DeCOI Host Genetics Group, GEN-COVID Multicenter Study (Italy), Mount Sinai Clinical Intelligence Center, GEN-COVID consortium (Spain), GenOMICC Consortium, Japan COVID-19 Task Force, Regeneron Genetics Center, Geschwind DH, Arteaga S, Stephens A, Butte MJ, Boutros PC, Yamaguchi TN, Tao S, Eng S, Sanders T, Tung PJ, Broudy ME, Pan Y, Gonzalez A, Chavan N, Johnson R, Pasaniuc B, Yaspan B, Smieszek S, Rivolta C, Bibert S, Bochud PY, Dabrowski M, Zawadzki P, Sypniewski M, Kaja E, Chariyavilaskul P, Nilaratanakul V, Hirankarn N, Shotelersuk V, Pongpanich M, Phokaew C, Chetruengchai W, Tokunaga K, Sugiyama M, Kawai Y, Hasegawa T, Naito T, Namkoong H, Edahiro R, Kimura A, Ogawa S, Kanai T, Fukunaga K, Okada Y, Imoto S, Miyano S, Mangul S, Abedalthagafi MS, Zeberg H, Grzymski JJ, Washington NL, Ossowski S, Ludwig KU, Schulte EC, Riess O, Moniuszko M, Kwasniewski M, Mbarek H, Ismail SI, Verma A, Goldstein DB, Kiryluk K, Renieri A, Ferreira MAR, Richards JB. Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. PLoS Genet. 2022 11; 18(11):e1010367. PMID: 36327219; PMCID: PMC9632827.
      Citations: 13     Fields:    Translation:HumansCells
    14. Nurjadi D, R?ter J, Pallerla SR, Meyer CG, Casadei N, Sonnabend M, Peter S, Linh LTK, Fendel R, G?pel S, Riess O, Kremsner PG, Velavan TP. Host genetic loci LZTFL1 and CCL2 associated with SARS-CoV-2 infection and severity of COVID-19. Int J Infect Dis. 2022 Sep; 122:427-436. PMID: 35753602; PMCID: PMC9222649.
      Citations: 5     Fields:    Translation:HumansCells
    15. Weber JJ, Anger SC, Pereira Sena P, Incebacak Eltemur RD, Huridou C, Fath F, Gross C, Casadei N, Riess O, Nguyen HP. Calpains as novel players in the molecular pathogenesis of spinocerebellar ataxia type 17. Cell Mol Life Sci. 2022 Apr 28; 79(5):262. PMID: 35482253; PMCID: PMC9050766.
      Citations: 3     Fields:    Translation:AnimalsCells
    16. Ampa R, Nguimbi E, Montaldo C, Mfoutou Mapanguy CC, Batchi-Bouyou AL, Djontu JC, Pallerla SR, Ngoma CH, Linh LTK, Rachakonda S, Casadei N, Angelov A, Sonnabend M, Vouvoungui JC, Peter S, Kremsner PG, Velavan TP, Ntoumi F. SARS-CoV-2 B.1.214.1, B.1.214.2 and B.1.620 are predominant lineages between December 2020 and July 2021 in the Republic of Congo. IJID Reg. 2022 Jun; 3:106-113. PMID: 35720148; PMCID: PMC8907106.
      Citations: 1     
    17. Dietz S, Schwarz J, Casadei N, Poets CF, Gille C, Velic A, Gonz?lez-Men?ndez I, Quintanilla-Martinez L, Marm? A, K?stlin-Gille N. Human Leucocyte Antigen G and Murine Qa-2 Are Critical for Myeloid Derived Suppressor Cell Expansion and Activation and for Successful Pregnancy Outcome. Front Immunol. 2021; 12:787468. PMID: 35111157; PMCID: PMC8801456.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    18. Moussian B, Casadei N. Identification and Functional Characterization of Argonaute (Ago) Proteins in Insect Genomes. Methods Mol Biol. 2022; 2360:9-17. PMID: 34495503.
      Citations: 1     Fields:    Translation:Animals
    19. Barbuti PA, Ohnmacht J, Santos BFR, Antony PM, Dording CM, Pavelka L, Kwon YJ, Massart F, Cruciani G, Casadei N, Kr?ger R. Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function. Sci Rep. 2021 11 09; 11(1):21946. PMID: 34754035; PMCID: PMC8578337.
      Citations: 2     Fields:    Translation:HumansCells
    20. Zimmermann F, Mills JD, Aronica E, Haas E, Incebacak RD, Hentrich T, Huridou C, Schmidt T, Casadei N, Maringer Y, Bahl C, Riess O, Schulze-Hentrich JM, H?bener-Schmid J. A Novel SCA3 Knock-in Mouse Model Mimics the Human SCA3 Disease Phenotype Including Neuropathological, Behavioral, and Transcriptional Abnormalities Especially in Oligodendrocytes. Mol Neurobiol. 2022 Jan; 59(1):495-522. PMID: 34716557; PMCID: PMC8786755.
      Citations: 17     Fields:    Translation:AnimalsCells
    21. Brunk F, Moritz A, Nelde A, Bilich T, Casadei N, Fraschka SAK, Heitmann JS, H?rber S, Peter A, Rammensee HG, Singh H, Walz J, Maurer D, Wagner C. SARS-CoV-2-reactive T-cell receptors isolated from convalescent COVID-19 patients confer potent T-cell effector function. Eur J Immunol. 2021 11; 51(11):2651-2664. PMID: 34424997; PMCID: PMC8646365.
      Citations: 7     Fields:    Translation:HumansCells
    22. Sevgi F, Brauchle EM, Carvajal Berrio DA, Schenke-Layland K, Casadei N, Salker MS, Riess O, Singh Y. Imaging of a-Synuclein Aggregates in a Rat Model of Parkinson's Disease Using Raman Microspectroscopy. Front Cell Dev Biol. 2021; 9:664365. PMID: 34568310; PMCID: PMC8461246.
      Citations: 6     
    23. Grahammer F, Izem L, Plow EF, Bohnert BN, Gonzalez-Menendez I, D?rffel T, Schneider JC, Xiao M, Janessa A, Kalo MZ, Fehrenbacher B, Schaller M, Casadei N, Amann K, Daniel C, Birkenfeld AL, Quintanilla-Martinez L, Artunc F. Essential role of DNA-PKcs and plasminogen for the development of doxorubicin-induced glomerular injury in mice. Dis Model Mech. 2021 09 01; 14(9). PMID: 34423816; PMCID: PMC8461821.
      Citations: 2     Fields:    Translation:HumansAnimals
    24. Schwarz L, Casadei N, Fitzgerald JC. Generation of R272Q, S156A and K572R RHOT1/Miro1 point mutations in iPSCs from a healthy individual using FACS-assisted CRISPR/Cas9 genome editing. Stem Cell Res. 2021 08; 55:102469. PMID: 34359002.
      Citations: 1     Fields:    Translation:Humans
    25. Vangala D, Ladigan S, Liffers ST, Noseir S, Maghnouj A, Verdoodt B, Klein-Scory S, Godfrey L, Zowada MK, Huerta M, Edelstein DL, de Villarreal JM, Jung A, Schiergens T, Werner J, Heinemann V, Pohl M, Teschendorf C, Bernhardt C, Wolters H, Stern J, Usta S, Viebahn R, Ball CR, Siveke JT, Glimm H, Tannapfel A, Schmiegel W, Hahn SA, G?tze TM, Marqu?s M, Kumbrink J, Stintzing S, Lindoerfer D, Mansmann U, Admard J, Casadei N, Fr?hling S. Secondary resistance to anti-EGFR therapy by transcriptional reprogramming in patient-derived colorectal cancer models. Genome Med. 2021 07 16; 13(1):116. PMID: 34271981; PMCID: PMC8283888.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    26. Deutsche COVID-19 OMICS Initiate (DeCOI), Singh Y, Trautwein C, Fendel R, Krickeberg N, Berezhnoy G, Bissinger R, Ossowski S, Salker MS, Casadei N, Riess O. SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells. Heliyon. 2021 Jun; 7(6):e07147. PMID: 34075347; PMCID: PMC8159709.
      Citations: 11     
    27. Schultze H, Shastry KL, Manamohan S, Mukherjee S, Garg V, Sarveswara R, Pickkers P, Ktena S, Tran F, Herr C, Petersheim D, Behrends U, Schommers P, Lehmann C, Augustin M, Rybniker J, Mishra N, Bernardes JP, Siever C, Desai M, Monnet B, Saridaki M, Siegel CM, Schreiber S, Kim-Hellmuth S, COVID-19 Aachen Study (COVAS), Nattermann J, Skowasch D, Kurth I, Bals R, Rosenstiel P, Netea MG, Theis F, Deutsche COVID-19 Omics Initiative (DeCOI), Giamarellos-Bourboulis EJ, Kox M, Cheran S, Woodacre MS, Goh EL, Warnat-Herresthal S, H?ndler K, Aziz NA, Bitzer M, Ossowski S, Casadei N, Kern F, Fehlmann T, Altm?ller J, Kr?mer B, Bonaguro L, Schulte-Schrepping J, De Domenico E, Kraut M, Drews A, Nuesch-Germano M, Theis H, Heyckendorf J, Keller A, N?rnberg P, Rie? O, Mukherjee S, Backes M, Aschenbrenner AC, Ulas T, Breteler MMB, Becker M, Schultze JL. Swarm Learning for decentralized and confidential clinical machine learning. Nature. 2021 06; 594(7862):265-270. PMID: 34040261; PMCID: PMC8189907.
      Citations: 107     Fields:    Translation:HumansCellsPHPublic Health
    28. Dyack S, MacKay SB, Schatz U, Fleger M, Kurringer A, Balousha G, Ghanim Z, Alkuraya FS, Alzaidan H, Alsaif HS, Mitani T, Bozdogan S, Pehlivan D, Lupski JR, Gleeson JJ, Dehghani M, Mehrjardi MYV, Sherr EH, Parks KC, Argilli E, Begtrup A, Galehdari H, Balousha O, Shariati G, Mazaheri N, Malamiri RA, Pagnamenta AT, Kingston H, Banka S, Jackson A, Osmond M, Care4Rare Canada Consortium, Genomics England Research Consortium, Houlden H, Maroofian R, Hengel H, Hannan SB, Rie? A, Haack TB, N?gele T, Schuster S, Hauser S, Admard J, Casadei N, Velic A, Macek B, Ossowski S, Sch?ls L. Bi-allelic loss-of-function variants in BCAS3 cause a syndromic neurodevelopmental disorder. Am J Hum Genet. 2021 06 03; 108(6):1069-1082. PMID: 34022130; PMCID: PMC8206390.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    29. Ntoumi F, Mfoutou Mapanguy CC, Tomazatos A, Pallerla SR, Linh LTK, Casadei N, Angelov A, Sonnabend M, Peter S, Kremsner PG, Velavan TP. Genomic surveillance of SARS-CoV-2 in the Republic of Congo. Int J Infect Dis. 2021 Apr; 105:735-738. PMID: 33737129; PMCID: PMC7959680.
      Citations: 15     Fields:    Translation:HumansCells
    30. Boyken J, Admard J, Casadei N, Jost G, Frenzel T, Schmitz C, Pietsch H, Habermeyer J, Harrer J, Canneva F, Ratz V, Moceri S, B?uerle T, Sch?tz G, von H?rsten S. Comprehensive phenotyping revealed transient startle response reduction and histopathological gadolinium localization to perineuronal nets after gadodiamide administration in rats. Sci Rep. 2020 12 28; 10(1):22385. PMID: 33372182; PMCID: PMC7769977.
      Citations: 6     Fields:    Translation:Animals
    31. Yazdi AS, Holstein J, Solimani F, Baum C, Meier K, Pollmann R, Didona D, Tekath T, Dugas M, Casadei N, Hudemann C, Polakova A, Matthes J, Sch?fer I, Eming R, Hertl M, Pf?tzner W, Ghoreschi K, M?bs C. Immunophenotyping in pemphigus reveals a TH17/TFH17 cell-dominated immune response promoting desmoglein1/3-specific autoantibody production. J Allergy Clin Immunol. 2021 06; 147(6):2358-2369. PMID: 33221382.
      Citations: 25     Fields:    Translation:HumansCells
    32. Polissidis A, Koronaiou M, Kollia V, Koronaiou E, Nakos-Bimpos M, Bogiongko M, Vrettou S, Karali K, Sardi SP, Xilouri M, Stefanis L, Casadei N, Riess O. Psychosis-Like Behavior and Hyperdopaminergic Dysregulation in Human a-Synuclein BAC Transgenic Rats. Mov Disord. 2021 03; 36(3):716-728. PMID: 33200461.
      Citations: 5     Fields:    Translation:HumansAnimals
    33. Arena G, Ugun-Klusek A, Bus C, Zizmare L, Feldkaemper M, Geisler S, Zarani M, Schaedler A, Klose F, Admard J, Mageean CJ, Fallier-Becker P, Maruszczak KK, Kapolou K, Schmid B, Rapaport D, Ueffing M, Casadei N, Kr?ger R, Gasser T, Vogt Weisenhorn DM, Kahle PJ, Trautwein C, Gloeckner CJ, Fitzgerald JC. Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors. iScience. 2020 Dec 18; 23(12):101797. PMID: 33299968; PMCID: PMC7702004.
      Citations: 11     
    34. Wassouf Z, Mills JD, Aronica E, Outeiro TF, Hentrich T, Ehrhardt C, Haas E, H?bener-Schmid J, Riess O, Casadei N, Schulze-Hentrich JM. Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson's disease patients. Aging (Albany NY). 2020 Oct 05; 12(19):18889-18906. PMID: 33017301; PMCID: PMC7732335.
      Citations: 5     Fields:    
    35. Dhariwal A, Pachauri V, Park DS, Mak TW, Singh Y, Trautwein C, Salker MS, Alauddin M, Zizmare L, Pelzl L, Feger M, Admard J, Casadei N, F?ller M, Frick JS, Wallwiener D, Brucker SY, Lang F, Riess O. DJ-1 (Park7) affects the gut microbiome, metabolites and the development of innate lymphoid cells (ILCs). Sci Rep. 2020 09 30; 10(1):16131. PMID: 32999308; PMCID: PMC7528091.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    36. Maia A, Hentrich T, Koch A, Weber N, Kilzheimer A, Burkhardt S, Rall K, Casadei N, Kohlbacher O, Riess O, Schulze-Hentrich JM, Brucker SY. The Endometrial Transcription Landscape of MRKH Syndrome. Front Cell Dev Biol. 2020; 8:572281. PMID: 33072755; PMCID: PMC7542331.
      Citations: 12     
    37. Epting T, Siegmund DM, Lamsfus-Calle A, Daniel-Moreno A, Antony JS, Heumos L, Baskaran P, Admard J, Casadei N, Latifi N, Kormann MSD, Handgretinger R, Mezger M. Comparative targeting analysis of KLF1, BCL11A, and HBG1/2 in CD34+ HSPCs by CRISPR/Cas9 for the induction of fetal hemoglobin. Sci Rep. 2020 06 23; 10(1):10133. PMID: 32576837; PMCID: PMC7311455.
      Citations: 21     Fields:    Translation:HumansCells
    38. Chishti AH, Weber JJ, Haas E, Maringer Y, Hauser S, Casadei NLP, Riess O, H?bener-Schmid J. Calpain-1 ablation partially rescues disease-associated hallmarks in models of Machado-Joseph disease. Hum Mol Genet. 2020 04 15; 29(6):892-906. PMID: 31960910; PMCID: PMC7158375.
      Citations: 9     Fields:    Translation:AnimalsCells
    39. Cheng F, Walter M, Wassouf Z, Hentrich T, Casadei N, Schulze-Hentrich J, Barbuti P, Krueger R, Riess O, Grundmann-Hauser K, Ott T. Unraveling Molecular Mechanisms of THAP1 Missense Mutations in DYT6 Dystonia. J Mol Neurosci. 2020 Jul; 70(7):999-1008. PMID: 32112337; PMCID: PMC7334247.
      Citations: 6     Fields:    Translation:HumansCells
    40. Pasquini G, Swiersy A, Wimmer T, Stieger K, Busskamp V, Cora V, Achberger K, Antkowiak L, M?ller B, Fraschka SA, Casadei N, Ueffing M, Liebau S. Using Transcriptomic Analysis to Assess Double-Strand Break Repair Activity: Towards Precise in vivo Genome Editing. Int J Mol Sci. 2020 Feb 18; 21(4). PMID: 32085662; PMCID: PMC7073035.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    41. Lohmann E, Hoischen A, Pogoda M, Hilke FJ, Sturm M, Lenz F, Matthes J, Muyas F, Ossowski S, Faust U, Sepahi I, Casadei N, Poths S, Riess O, Schroeder C, Grundmann K. Single Molecule Molecular Inversion Probes for High Throughput Germline Screenings in Dystonia. Front Neurol. 2019; 10:1332. PMID: 31920950; PMCID: PMC6930228.
      Citations: 1     
    42. Timotius IK, Moceri S, Plank AC, Habermeyer J, Canneva F, Winkler J, Klucken J, Casadei N, Riess O, Eskofier B, von H?rsten S. Silhouette-Length-Scaled Gait Parameters for Motor Functional Analysis in Mice and Rats. eNeuro. 2019 Nov/Dec; 6(6). PMID: 31604813; PMCID: PMC6825954.
      Citations: 6     Fields:    Translation:Animals
    43. Huson D, Singh Y, El-Hadidi M, Admard J, Wassouf Z, Schulze-Hentrich JM, Kohlhofer U, Quintanilla-Martinez L, Riess O, Casadei N. Enriched Environmental Conditions Modify the Gut Microbiome Composition and Fecal Markers of Inflammation in Parkinson's Disease. Front Neurosci. 2019; 13:1032. PMID: 31749671; PMCID: PMC6842954.
      Citations: 11     
    44. Krashia P, Cordella A, Nobili A, La Barbera L, Federici M, Leuti A, Campanelli F, Natale G, Marino G, Calabrese V, Vedele F, Ghiglieri V, Picconi B, Di Lazzaro G, Schirinzi T, Sancesario G, Bernardini S, Pisani A, Calabresi P, Serhan CN, D'Amelio M, Mercuri NB, Casadei N, Riess O, Viscomi MT, Chiurchi? V. Author Correction: Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease. Nat Commun. 2019 Oct 14; 10(1):4725. PMID: 31611555; PMCID: PMC6791874.
      Citations: 8     Fields:    
    45. Nakanishi E, Geisler S, J?ger L, Golombek S, Hans F, Casadei N, Terradas AL, Linnemann C, Kahle PJ. Ubiquitin-specific protease USP36 knockdown impairs Parkin-dependent mitophagy via downregulation of Beclin-1-associated autophagy-related ATG14L. Exp Cell Res. 2019 11 15; 384(2):111641. PMID: 31550441.
      Citations: 13     Fields:    Translation:HumansCells
    46. Krashia P, Cordella A, Nobili A, La Barbera L, Federici M, Leuti A, Campanelli F, Natale G, Marino G, Calabrese V, Vedele F, Ghiglieri V, Picconi B, Di Lazzaro G, Schirinzi T, Sancesario G, Bernardini S, Pisani A, Calabresi P, Serhan CN, D'Amelio M, Mercuri NB, Casadei N, Riess O, Viscomi MT, Chiurchi? V. Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease. Nat Commun. 2019 09 02; 10(1):3945. PMID: 31477726; PMCID: PMC6718379.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    47. Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefanczyk S, Lindner C, Oswald B, Bernhard R, H?hnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, M?ller P, Bajoghli B, Skokowa J. LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. Blood. 2019 10 03; 134(14):1159-1175. PMID: 31366618; PMCID: PMC6888148.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    48. Blaeschke F, Paul MC, Wagner B, Kaeuferle T, Willier S, Feuchtinger T, Schuhmann MU, Rabsteyn A, Schroeder C, Casadei N, Matthes J, Mohr C, Lotfi R, Feucht J, Handgretinger R, StevanoviC S, Lang P. Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy. Cytotherapy. 2019 09; 21(9):973-986. PMID: 31351799.
      Citations: 17     Fields:    Translation:HumansCells
    49. Timotius IK, Canneva F, Minakaki G, Moceri S, Plank AC, Casadei N, Riess O, Winkler J, Klucken J, Eskofier B, von H?rsten S. Systematic data analysis and data mining in CatWalk gait analysis by heat mapping exemplified in rodent models for neurodegenerative diseases. J Neurosci Methods. 2019 10 01; 326:108367. PMID: 31351096.
      Citations: 7     Fields:    Translation:HumansAnimals
    50. Van Den Berge N, Ferreira N, Gram H, Mikkelsen TW, Alstrup AKO, Casadei N, Tsung-Pin P, Riess O, Nyengaard JR, Jensen PH, Borghammer P, Tamg?ney G. Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats. Acta Neuropathol. 2019 10; 138(4):535-550. PMID: 31254094; PMCID: PMC6778265.
      Citations: 117     Fields:    Translation:AnimalsCells
    51. Classen J, Dresel C, Jost W, Reichmann H, Storch A, van Eimeren T, Zunke F, Riederer P, Berg D, Casadei N, Cheng F, Kr?ger R, M?ller T, Rie? O, Strobel S, V?lker HU, Winkler J, Winklhofer KF, W?llner U, Monoranu CM. a-Synuclein in Parkinson's disease: causal or bystander? J Neural Transm (Vienna). 2019 07; 126(7):815-840. PMID: 31240402.
      Citations: 43     Fields:    Translation:HumansAnimals
    52. Wassouf Z, Hentrich T, Casadei N, Jaumann M, Knipper M, Riess O, Schulze-Hentrich JM. Distinct Stress Response and Altered Striatal Transcriptome in Alpha-Synuclein Overexpressing Mice. Front Neurosci. 2018; 12:1033. PMID: 30686992; PMCID: PMC6336091.
      Citations: 5     
    53. Canneva F, Timotius IK, Kalinichenko LS, Eskofier BM, Xiang W, Minakaki G, Chevessier F, Bode F, Menges S, Meixner H, M?ller CP, Casadei N, Riess O, Schr?der R, Winkler J, von H?rsten S, Klucken J. Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy. Behav Brain Res. 2019 05 02; 363:199-215. PMID: 30599154.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    54. Yu-Taeger L, Gaiser V, Lotzer L, Roenisch T, Fabry BT, Stricker-Shaver J, Casadei N, Walter M, Schaller M, Riess O, Nguyen HP, Ott T, Grundmann-Hauser K. Dynamic nuclear envelope phenotype in rats overexpressing mutated human torsinA protein. Biol Open. 2018 Jul 23; 7(7). PMID: 29739751; PMCID: PMC6078351.
      Citations:    Fields:    
    55. Wassouf Z, Hentrich T, Samer S, Rotermund C, Kahle PJ, Ehrlich I, Riess O, Casadei N, Schulze-Hentrich JM. Environmental Enrichment Prevents Transcriptional Disturbances Induced by Alpha-Synuclein Overexpression. Front Cell Neurosci. 2018; 12:112. PMID: 29755323; PMCID: PMC5932345.
      Citations: 15     
    56. Timotius IK, Canneva F, Minakaki G, Pasluosta C, Moceri S, Casadei N, Riess O, Winkler J, Klucken J, von H?rsten S, Eskofier B. Dynamic footprints of a-synucleinopathic mice recorded by CatWalk gait analysis. Data Brief. 2018 Apr; 17:189-193. PMID: 29876385; PMCID: PMC5988224.
      Citations: 3     
    57. Timotius IK, Canneva F, Minakaki G, Pasluosta C, Moceri S, Casadei N, Riess O, Winkler J, Klucken J, von H?rsten S, Eskofier B. Dynamic footprint based locomotion sway assessment in a-synucleinopathic mice using Fast Fourier Transform and Low Pass Filter. J Neurosci Methods. 2018 02 15; 296:1-11. PMID: 29253577.
      Citations: 6     Fields:    Translation:HumansAnimals
    58. Kieper N, Glaab E, Fitzgerald JC, Casadei N, Sood P, Ulrich T, Fallier-Becker P, Helling S, May C, Chen J, Nuber S, Wolburg H, Marcus K, Rapaport D, Ott T, Riess O, Kr?ger R. Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2. Hum Mol Genet. 2016 12 15; 25(24):5513. PMID: 28031291.
      Citations: 1     Fields:    
    59. Glaab E, Wolburg H, Casadei N, Sood P, Ulrich T, Fallier-Becker P, Kieper N, Helling S, May C, Chen J, Nuber S, Marcus K, Rapaport D, Ott T, Riess O, Kr?ger R, Fitzgerald JC. Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2. Hum Mol Genet. 2016 02 01; 25(3):459-71. PMID: 26604148.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    60. Van der Perren A, Toelen J, Casteels C, Macchi F, Van Rompuy AS, Sarre S, Himmelreich U, Osorio Garcia MI, Michotte Y, D'Hooge R, Bormans G, Van Laere K, Gijsbers R, Van den Haute C, Debyser Z, Baekelandt V, Casadei N, Nuber S. Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors. Neurobiol Aging. 2015 Mar; 36(3):1543-58. PMID: 25599874.
      Citations: 41     Fields:    Translation:AnimalsCells
    61. Diepenbroek M, Casadei N, Esmer H, Saido TC, Takano J, Nixon RA, Rao MV, Melki R, Pieri L, Helling S, Marcus K, Masliah E, Riess O, Nuber S, Kahle PJ, Krueger R. Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]aSyn transgenic mice. Hum Mol Genet. 2014 Aug 01; 23(15):3975-89. PMID: 24619358; PMCID: PMC4110482.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    62. Van der Perren A, Casadei N, Stroobants S, Nuber S, D'Hooge R, Van den Haute C, Baekelandt V, Oliveras-Salv? M. rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration. Mol Neurodegener. 2013 Nov 25; 8:44. PMID: 24267638; PMCID: PMC4222878.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    63. Schwedhelm I, Witz A, Zamolo I, De Heer R, Spruijt B, Noldus LP, Klucken J, Kahle PJ, Riess O, Nuber S, Casadei N, P?hler AM, Tom?s-Zapico C, Torres-Peraza J, Lucas JJ, Kr?ger R. Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice. Hum Mol Genet. 2014 Feb 01; 23(3):767-81. PMID: 24064336.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    64. Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O, Sch?nig K, M?ller CP. A progressive dopaminergic phenotype associated with neurotoxic conversion of a-synuclein in BAC-transgenic rats. Brain. 2013 Feb; 136(Pt 2):412-32. PMID: 23413261; PMCID: PMC3572936.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    65. Casadei N, Teismann P, Seeliger MW, Riess O, Nguyen HP, H?bener J, Bj?rkqvist M, von H?rsten S. Automated behavioral phenotyping reveals presymptomatic alterations in a SCA3 genetrap mouse model. J Genet Genomics. 2012 Jun 20; 39(6):287-99. PMID: 22749017.
      Citations: 8     Fields:    Translation:AnimalsCells
    66. Franck T, Wolburg H, Schumann U, Casadei N, Fischer K, Calaminus C, Pichler BJ, Chanarat S, Teismann P, Luft AR, Wilbertz J, Bornemann A, Riess O, Nuber S, Schulz JB, Tomiuk J, Kr?ger R. Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice. Neurogenetics. 2010 Feb; 11(1):107-20. PMID: 19760259.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    67. Thomassin M, Guillaume YC, Casadei N, Andr? C. A humic acid stationary phase for the high performance liquid chromatography separation of buckminsterfullerenes: theoretical and practical aspects. Anal Chim Acta. 2007 Apr 11; 588(2):268-73. PMID: 17386820.
      Citations: 1     Fields:    

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