"Wnt Signaling Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, and the vertebrate INT gene. The signaling pathway is initiated by the binding of WNT PROTEINS to cell surface WNT RECEPTORS which interact with the AXIN SIGNALING COMPLEX and an array of second messengers that influence the actions of BETA CATENIN.
Descriptor ID |
D060449
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MeSH Number(s) |
G02.111.820.925 G04.835.925
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Concept/Terms |
Wnt Signaling Pathway- Wnt Signaling Pathway
- Pathway, Wnt Signaling
- Pathways, Wnt Signaling
- Signaling Pathway, Wnt
- Signaling Pathways, Wnt
- Wnt Signaling Pathways
- Wnt Pathway
- Pathway, Wnt
- Pathways, Wnt
- Wnt Pathways
Wnt beta-Catenin Signaling Pathway- Wnt beta-Catenin Signaling Pathway
- Wnt beta Catenin Signaling Pathway
- Wnt Pathway, Canonical
- Canonical Wnt Pathway
- Canonical Wnt Pathways
- Pathway, Canonical Wnt
- Pathways, Canonical Wnt
- Wnt Pathways, Canonical
|
Below are MeSH descriptors whose meaning is more general than "Wnt Signaling Pathway".
Below are MeSH descriptors whose meaning is more specific than "Wnt Signaling Pathway".
This graph shows the total number of publications written about "Wnt Signaling Pathway" by people in this website by year, and whether "Wnt Signaling Pathway" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 0 | 1 | 1 |
2013 | 1 | 2 | 3 |
2014 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2019 | 2 | 1 | 3 |
2020 | 0 | 3 | 3 |
2021 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Wnt Signaling Pathway" by people in Profiles.
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Monoallelic and biallelic variants in LEF1 are associated with a new syndrome combining ectodermal dysplasia and limb malformations caused by altered WNT signaling. Genet Med. 2022 08; 24(8):1708-1721.
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Circular RNA profiling distinguishes medulloblastoma groups and shows aberrant RMST overexpression in WNT medulloblastoma. Acta Neuropathol. 2021 06; 141(6):975-978.
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Animal development in the microbial world: The power of experimental model systems. Curr Top Dev Biol. 2021; 141:371-397.
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CRELD1 modulates homeostasis of the immune system in mice and humans. Nat Immunol. 2020 12; 21(12):1517-1527.
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Bacteria- and temperature-regulated peptides modulate ?-catenin signaling in Hydra. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21459-21468.
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Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways. Nat Commun. 2019 07 22; 10(1):3257.
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GLI3 repressor but not GLI3 activator is essential for mouse eye patterning and morphogenesis. Dev Biol. 2019 06 15; 450(2):141-154.
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Sfrp5 increases glucose-stimulated insulin secretion in the rat pancreatic beta cell line INS-1E. PLoS One. 2019; 14(3):e0213650.
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Novel mutations in LRP6 highlight the role of WNT signaling in tooth agenesis. Genet Med. 2016 11; 18(11):1158-1162.
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NatalieQ: a web server for protein-protein interaction network querying. BMC Syst Biol. 2014 Apr 01; 8:40.