"Cyclin D1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.
| Descriptor ID |
D019938
|
| MeSH Number(s) |
D12.644.360.262.150.100 D12.776.167.218.150.100 D12.776.476.262.150.100 D12.776.624.664.700.100
|
| Concept/Terms |
Cyclin D1- Cyclin D1
- Proto-Oncogene Products bcl-1
- Proto Oncogene Products bcl 1
- Proto-Oncogene Protein bcl-1
- Proto Oncogene Protein bcl 1
- bcl-1, Proto-Oncogene Protein
- bcl-1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl-1
- bcl 1 Proto Oncogene Proteins
- CCND1 Protein
- PRAD1 Protein
- bcl-1 Proto-Oncogene Products
- Proto-Oncogene Products, bcl-1
- bcl 1 Proto Oncogene Products
- bcl1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl1
- bcl1 Proto Oncogene Proteins
- Proto-Oncogene Proteins c-bcl-1
- Proto Oncogene Proteins c bcl 1
- c-bcl-1, Proto-Oncogene Proteins
- c-bcl-1 Proteins
- c bcl 1 Proteins
|
Below are MeSH descriptors whose meaning is more general than "Cyclin D1".
Below are MeSH descriptors whose meaning is more specific than "Cyclin D1".
This graph shows the total number of publications written about "Cyclin D1" by people in this website by year, and whether "Cyclin D1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclin D1" by people in Profiles.
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Ablation of the Sox11 Gene Results in Clefting of the Secondary Palate Resembling the Pierre Robin Sequence. J Biol Chem. 2016 Mar 25; 291(13):7107-18.
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CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo. J Exp Med. 2015 Jul 27; 212(8):1171-83.
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Genomic high-resolution profiling of single CKpos/CD45neg flow-sorting purified circulating tumor cells from patients with metastatic breast cancer. Clin Chem. 2014 Oct; 60(10):1290-7.
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The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma. Nat Genet. 2013 May; 45(5):522-525.
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Cyclin D1-specific cytotoxic T lymphocytes are present in the repertoire of cancer patients: implications for cancer immunotherapy. Clin Cancer Res. 2008 Oct 15; 14(20):6574-9.
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Modulation of gene expression profiles by hyperosmolarity and insulin. Cell Physiol Biochem. 2007; 20(5):369-86.
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Oligonucleotide microarray analysis of differential transporter regulation in the regenerating rat liver. Liver Int. 2005 Dec; 25(6):1243-58.
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Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras. J Biol Chem. 2001 Nov 16; 276(46):42834-42.
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Implication of atypical protein kinase C isozymes lambda and zeta in Ras mediated reorganization of the actin cytoskeleton and cyclin D1-induction. Adv Enzyme Regul. 2000; 40:49-62.
MeSH information
