"RNA-Binding Protein FUS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.
| Descriptor ID |
D034702
|
| MeSH Number(s) |
D12.776.157.725.813.750.905 D12.776.624.664.700.915 D12.776.664.962.813.750.902
|
| Concept/Terms |
RNA-Binding Protein FUS- RNA-Binding Protein FUS
- RNA Binding Protein FUS
- TLS Protein
- POMp75 Protein
- Translocated in Liposarcoma Protein
- FUS RNA-Binding Protein
- FUS RNA Binding Protein
- RNA-Binding Protein, FUS
- Fusion Protein in Myxoid Liposarcoma
- FUS Protein
- hnRNP P2
|
Below are MeSH descriptors whose meaning is more general than "RNA-Binding Protein FUS".
Below are MeSH descriptors whose meaning is more specific than "RNA-Binding Protein FUS".
This graph shows the total number of publications written about "RNA-Binding Protein FUS" by people in this website by year, and whether "RNA-Binding Protein FUS" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "RNA-Binding Protein FUS" by people in Profiles.
-
De novo FUS mutations are the most frequent genetic cause in early-onset German ALS patients. Neurobiol Aging. 2015 Nov; 36(11):3117.e1-3117.e6.
-
NKAP is a novel RS-related protein that interacts with RNA and RNA binding proteins. Nucleic Acids Res. 2014 Mar; 42(5):3177-93.
-
RNA targets of wild-type and mutant FET family proteins. Nat Struct Mol Biol. 2011 Nov 13; 18(12):1428-31.
MeSH information
