"Cyclins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators.
Descriptor ID |
D016213
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MeSH Number(s) |
D12.644.360.262 D12.776.167.218 D12.776.476.262
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclins".
Below are MeSH descriptors whose meaning is more specific than "Cyclins".
This graph shows the total number of publications written about "Cyclins" by people in this website by year, and whether "Cyclins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclins" by people in Profiles.
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Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma. Proc Natl Acad Sci U S A. 2018 09 11; 115(37):9282-9287.
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Using CD40-activated B cells to efficiently identify epitopes of tumor antigens. J Immunother. 2009 Feb-Mar; 32(2):157-60.
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Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1. J Clin Invest. 2008 Sep; 118(9):3132-42.
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Gene expression profiling of follicular lymphoma and normal germinal center B cells using cDNA arrays. Blood. 2002 Jan 01; 99(1):282-9.