"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
Descriptor ID |
D015496
|
MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
|
Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2006 | 2 | 0 | 2 |
2007 | 3 | 0 | 3 |
2008 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2012 | 2 | 0 | 2 |
2013 | 1 | 0 | 1 |
2014 | 1 | 1 | 2 |
2015 | 2 | 0 | 2 |
2016 | 2 | 1 | 3 |
2017 | 2 | 1 | 3 |
2019 | 3 | 0 | 3 |
2020 | 2 | 2 | 4 |
2021 | 1 | 2 | 3 |
2022 | 0 | 2 | 2 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
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CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity. Nat Immunol. 2023 06; 24(6):979-990.
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Mycobacterium tuberculosis-specific CD4 T-cell scoring discriminates tuberculosis infection from disease. Eur Respir J. 2022 07; 60(1).
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Resolving SARS-CoV-2 CD4+ T?cell specificity via reverse epitope discovery. Cell Rep Med. 2022 08 16; 3(8):100697.
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Cognate recognition of microbial antigens defines constricted CD4+ T?cell receptor repertoires in the inflamed colon. Immunity. 2021 11 09; 54(11):2565-2577.e6.
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Leukocyte Counts and T-Cell Frequencies Differ Between Novel Subgroups of Diabetes and Are Associated With Metabolic Parameters and Biomarkers of Inflammation. Diabetes. 2021 11; 70(11):2652-2662.
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Decreased inflammatory cytokine production of antigen-specific CD4+ T?cells in NMDA receptor encephalitis. J Neurol. 2021 Jun; 268(6):2123-2131.
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Identification and characterization of antigen-specific CD4+ T cells targeting renally expressed antigens in human lupus nephritis with two independent methods. Sci Rep. 2020 12 04; 10(1):21312.
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Low-Avidity CD4+ T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19. Immunity. 2020 12 15; 53(6):1258-1271.e5.
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Nuclear antigen-reactive CD4+ T cells expand in active systemic lupus erythematosus, produce effector cytokines, and invade the kidneys. Kidney Int. 2021 01; 99(1):238-246.
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TCRs with segment TRAV9-2 or a CDR3 histidine are overrepresented among nickel-specific CD4+ T cells. Allergy. 2020 10; 75(10):2574-2586.