"Insulin-Like Growth Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
Descriptor ID |
D007334
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MeSH Number(s) |
D12.644.276.937.400 D12.776.124.862.400 D12.776.467.937.400 D23.529.937.400
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Concept/Terms |
Insulin-Like Growth Factor I- Insulin-Like Growth Factor I
- Insulin-Like Somatomedin Peptide I
- Insulin Like Somatomedin Peptide I
- Somatomedin C
- IGF-I-SmC
- IGF-1
- IGF-I
- Insulin Like Growth Factor I
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor I".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor I".
This graph shows the total number of publications written about "Insulin-Like Growth Factor I" by people in this website by year, and whether "Insulin-Like Growth Factor I" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2022 | 3 | 0 | 3 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor I" by people in Profiles.
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Metabolic surgery-induced changes of the growth hormone system relate to improved adipose tissue function. Int J Obes (Lond). 2023 06; 47(6):505-511.
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IGF1R expression by adult oligodendrocytes is not required in the steady-state but supports neuroinflammation. Glia. 2023 03; 71(3):616-632.
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Insulin-Like Growth Factor 1 Attenuates the Pro-Inflammatory Phenotype of Neutrophils in Myocardial Infarction. Front Immunol. 2022; 13:908023.
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Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice. Int J Mol Sci. 2022 May 17; 23(10).
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IGF1 Treatment Improves Cardiac Remodeling after Infarction by Targeting Myeloid Cells. Mol Ther. 2019 01 02; 27(1):46-58.
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Identification and characterization of two functional variants in the human longevity gene FOXO3. Nat Commun. 2017 12 12; 8(1):2063.
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Age to survive: DNA damage and aging. Trends Genet. 2008 Feb; 24(2):77-85.