"LIM Domain Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large class of structurally-related proteins that contain one or more LIM zinc finger domains. Many of the proteins in this class are involved in intracellular signaling processes and mediate their effects via LIM domain protein-protein interactions. The name LIM is derived from the first three proteins in which the motif was found: LIN-11, Isl1 and Mec-3.
| Descriptor ID |
D060588
|
| MeSH Number(s) |
D12.776.512
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "LIM Domain Proteins".
Below are MeSH descriptors whose meaning is more specific than "LIM Domain Proteins".
This graph shows the total number of publications written about "LIM Domain Proteins" by people in this website by year, and whether "LIM Domain Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "LIM Domain Proteins" by people in Profiles.
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Pseudotime analysis reveals novel regulatory factors for multigenic onset and monogenic transition of odorant receptor expression. Sci Rep. 2022 09 28; 12(1):16183.
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Meta-analyses identify DNA methylation associated with kidney function and damage. Nat Commun. 2021 12 09; 12(1):7174.
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Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction. Nat Commun. 2020 04 27; 11(1):2039.
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LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. Blood. 2019 10 03; 134(14):1159-1175.
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Lmo2 expression defines tumor cell identity during T-cell leukemogenesis. EMBO J. 2018 07 13; 37(14).
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Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure. Hypertension. 2017 10; 70(4):743-750.
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A modular gain-of-function approach to generate cortical interneuron subtypes from ES cells. Neuron. 2013 Dec 04; 80(5):1145-58.
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Array analysis of epilepsy-associated gangliogliomas reveals expression patterns related to aberrant development of neuronal precursors. Brain. 2008 Nov; 131(Pt 11):3034-50.
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Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1. J Clin Invest. 2008 Sep; 118(9):3132-42.
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Differential expression of LIM domain-only (LMO) genes in the developing mouse inner ear. Gene Expr Patterns. 2006 Oct; 6(8):857-63.
MeSH information
