"Toll-Like Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
| Descriptor ID |
D051193
|
| MeSH Number(s) |
D12.776.543.750.705.910.500
|
| Concept/Terms |
Toll-Like Receptors- Toll-Like Receptors
- Toll Like Receptors
- Toll-Like Receptor
- Receptor, Toll-Like
- Toll Like Receptor
- Receptors, Toll-Like
- Receptors, Toll Like
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptors".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptors".
This graph shows the total number of publications written about "Toll-Like Receptors" by people in this website by year, and whether "Toll-Like Receptors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Toll-Like Receptors" by people in Profiles.
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Cannabinoid receptor 2 is necessary to induce toll-like receptor-mediated microglial activation. Glia. 2022 01; 70(1):71-88.
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Absence of Non-Canonical, Inhibitory MYD88 Splice Variants in B Cell Lymphomas Correlates With Sustained NF-?B Signaling. Front Immunol. 2021; 12:616451.
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The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models. J Immunol. 2017 10 01; 199(7):2570-2584.
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Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2. Nature. 2017 06 29; 546(7660):662-666.
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MyD88-deficient Hydra reveal an ancient function of TLR signaling in sensing bacterial colonizers. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):19374-9.
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What hydra has to say about the role and origin of symbiotic interactions. Biol Bull. 2012 Aug; 223(1):78-84.
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FOXO-dependent regulation of innate immune homeostasis. Nature. 2010 Jan 21; 463(7279):369-73.
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Evolution and function of innate immune receptors--insights from marine invertebrates. J Innate Immun. 2009; 1(4):291-300.
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The evolution of immunity: a low-life perspective. Trends Immunol. 2007 Oct; 28(10):449-54.
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The innate immune repertoire in cnidaria--ancestral complexity and stochastic gene loss. Genome Biol. 2007; 8(4):R59.
MeSH information
