"RNA Interference" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
| Descriptor ID |
D034622
|
| MeSH Number(s) |
G05.308.203.374.790
|
| Concept/Terms |
RNA Interference- RNA Interference
- Interference, RNA
- Gene Silencing, Post-Transcriptional
- Gene Silencing, Post Transcriptional
- RNA Silencing
- Post-Transcriptional Gene Silencing
- Post Transcriptional Gene Silencing
- Post-Transcriptional Gene Silencings
- Silencing, Post-Transcriptional Gene
- RNAi
- Posttranscriptional Gene Silencing
- Gene Silencing, Posttranscriptional
- Gene Silencings, Posttranscriptional
|
Below are MeSH descriptors whose meaning is more general than "RNA Interference".
Below are MeSH descriptors whose meaning is more specific than "RNA Interference".
This graph shows the total number of publications written about "RNA Interference" by people in this website by year, and whether "RNA Interference" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 2 | 1 | 3 |
| 2006 | 0 | 3 | 3 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 3 | 3 |
| 2013 | 2 | 3 | 5 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 4 | 5 |
| 2016 | 0 | 3 | 3 |
| 2017 | 0 | 2 | 2 |
| 2019 | 1 | 2 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "RNA Interference" by people in Profiles.
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The Aedes aegypti RNA interference response against Zika virus in the context of co-infection with dengue and chikungunya viruses. PLoS Negl Trop Dis. 2023 Jul; 17(7):e0011456.
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Antiviral RNAi Response in Culex quinquefasciatus-Derived HSU Cells. Viruses. 2023 02 04; 15(2).
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Antiviral RNAi Response against the Insect-Specific Agua Salud Alphavirus. mSphere. 2022 02 23; 7(1):e0100321.
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Identification and Functional Characterization of Argonaute (Ago) Proteins in Insect Genomes. Methods Mol Biol. 2022; 2360:9-17.
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An Aedes aegypti-Derived Ago2 Knockout Cell Line to Investigate Arbovirus Infections. Viruses. 2021 06 03; 13(6).
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miR-518a-3p Suppresses Triple-Negative Breast Cancer Invasion and Migration Through Regulation of TMEM2. Technol Cancer Res Treat. 2020 Jan-Dec; 19:1533033820977523.
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Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery. FASEB J. 2019 08; 33(8):9235-9249.
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Comparative RNAi Screens in Isogenic Human Stem Cells Reveal SMARCA4 as a Differential Regulator. Stem Cell Reports. 2019 05 14; 12(5):1084-1098.
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Analysis of long non-coding RNA and mRNA expression in bovine macrophages brings up novel aspects of Mycobacterium avium subspecies paratuberculosis infections. Sci Rep. 2019 02 07; 9(1):1571.
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Detection of COPB2 as a KRAS synthetic lethal partner through integration of functional genomics screens. Oncotarget. 2017 May 23; 8(21):34283-34297.
MeSH information
