Next Generation Sequencing Competence Network

The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). It contains an N-terminal RING FINGER DOMAIN and is a PROTEIN PHOSPHATASE 1 regulatory subunit. In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)

Descriptor ID	D019313
MeSH Number(s)	D12.776.313.125 D12.776.624.776.100 D12.776.660.100 D12.776.744.100 D12.776.930.137
Concept/Terms	BRCA1 Protein BRCA1 Protein Breast Cancer Type 1 Susceptibility Protein Breast Cancer 1 Protein Ring Finger Protein 53 BRCA1 Gene Product Breast Cancer 1 Gene Product

Below are MeSH descriptors whose meaning is more general than "BRCA1 Protein".

Below are MeSH descriptors whose meaning is related to "BRCA1 Protein".

Below are MeSH descriptors whose meaning is more specific than "BRCA1 Protein".