"beta Catenin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.
Descriptor ID |
D051176
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MeSH Number(s) |
D12.776.091.249 D12.776.220.145.500 D12.776.930.130
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta Catenin".
Below are MeSH descriptors whose meaning is more specific than "beta Catenin".
This graph shows the total number of publications written about "beta Catenin" by people in this website by year, and whether "beta Catenin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2014 | 1 | 1 | 2 |
2015 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2019 | 1 | 1 | 2 |
2020 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta Catenin" by people in Profiles.
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Monoallelic and biallelic variants in LEF1 are associated with a new syndrome combining ectodermal dysplasia and limb malformations caused by altered WNT signaling. Genet Med. 2022 08; 24(8):1708-1721.
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Bacteria- and temperature-regulated peptides modulate ?-catenin signaling in Hydra. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21459-21468.
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Boundary maintenance in the ancestral metazoan Hydra depends on histone acetylation. Dev Biol. 2020 02 15; 458(2):200-214.
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Gene-gene interaction among cell adhesion genes and risk of nonsyndromic cleft lip with or without cleft palate in Chinese case-parent trios. Mol Genet Genomic Med. 2019 10; 7(10):e00872.
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Paired box 5 is a frequently methylated lung cancer tumour suppressor gene interfering ?-catenin signalling and GADD45G expression. J Cell Mol Med. 2016 May; 20(5):842-54.
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Control of AC133/CD133 and impact on human hematopoietic progenitor cells through nucleolin. Leukemia. 2015 Nov; 29(11):2208-20.
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De novo mutations in beta-catenin (CTNNB1) appear to be a frequent cause of intellectual disability: expanding the mutational and clinical spectrum. Hum Genet. 2015 Jan; 134(1):97-109.
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Genome-wide CNV analysis in 221 unrelated patients and targeted high-throughput sequencing reveal novel causative candidate genes for colorectal adenomatous polyposis. Int J Cancer. 2015 Mar 15; 136(6):E578-89.
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beta-catenin plays a central role in setting up the head organizer in hydra. Dev Biol. 2010 Apr 01; 340(1):116-24.
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Expression and tissue localization of beta-catenin, alpha-actinin and chondroitin sulfate proteoglycan 6 is modulated during rat and human left ventricular hypertrophy. Exp Mol Pathol. 2009 Feb; 86(1):23-31.