"Alternative Splicing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of EXONS during the processing of some, but not all, transcripts of the gene. Thus a particular exon may be connected to any one of several alternative exons to form a mature RNA. The alternative forms of mature MESSENGER RNA produce PROTEIN ISOFORMS in which one part of the isoforms is common while the other parts are different.
Descriptor ID |
D017398
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MeSH Number(s) |
G02.111.760.700.100 G03.839.700.100 G05.308.700.700.100
|
Concept/Terms |
Alternative Splicing- Alternative Splicing
- Alternative Splicings
- Splicings, Alternative
- Alternate Splicing
- Alternate Splicings
- Splicing, Alternate
- Splicings, Alternate
- RNA Splicing, Alternative
- Alternative RNA Splicing
- Alternative RNA Splicings
- RNA Splicings, Alternative
- Splicing, Alternative RNA
- Splicings, Alternative RNA
- Splicing, Alternative
Nested Transcripts- Nested Transcripts
- Nested Transcript
- Transcript, Nested
- Transcripts, Nested
|
Below are MeSH descriptors whose meaning is more general than "Alternative Splicing".
Below are MeSH descriptors whose meaning is more specific than "Alternative Splicing".
This graph shows the total number of publications written about "Alternative Splicing" by people in this website by year, and whether "Alternative Splicing" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2005 | 1 | 1 | 2 |
2007 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2012 | 0 | 4 | 4 |
2013 | 1 | 2 | 3 |
2015 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2018 | 1 | 1 | 2 |
2019 | 0 | 3 | 3 |
2020 | 1 | 1 | 2 |
2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Alternative Splicing" by people in Profiles.
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Absence of Non-Canonical, Inhibitory MYD88 Splice Variants in B Cell Lymphomas Correlates With Sustained NF-?B Signaling. Front Immunol. 2021; 12:616451.
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Arabidopsis ACINUS is O-glycosylated and regulates transcription and alternative splicing of regulators of reproductive transitions. Nat Commun. 2021 02 11; 12(1):945.
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Anything but Ordinary - Emerging Splicing Mechanisms in Eukaryotic Gene Regulation. Trends Genet. 2021 04; 37(4):355-372.
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NCX1 represents an ionic Na+ sensing mechanism in macrophages. PLoS Biol. 2020 06; 18(6):e3000722.
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Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration. Cell Oncol (Dordr). 2019 Oct; 42(5):691-703.
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Sequence and expression levels of circular RNAs in progenitor cell types during mouse corticogenesis. Life Sci Alliance. 2019 04; 2(2).
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Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma. Nat Commun. 2019 03 29; 10(1):1459.
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Analyses of LMNA-negative juvenile progeroid cases confirms biallelic POLR3A mutations in Wiedemann-Rautenstrauch-like syndrome and expands the phenotypic spectrum of PYCR1 mutations. Hum Genet. 2018 Dec; 137(11-12):921-939.
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Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity. Mol Cell. 2018 11 01; 72(3):482-495.e7.
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Sample Size Estimation for Detection of Splicing Events in Transcriptome Sequencing Data. Int J Mol Sci. 2017 Sep 05; 18(9).