"Mutagenesis, Insertional" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
| Descriptor ID |
D016254
|
| MeSH Number(s) |
E05.393.420.601.550 G05.365.590.575 G05.558.550
|
| Concept/Terms |
Sequence Insertion- Sequence Insertion
- Insertion, Sequence
- Insertions, Sequence
- Sequence Insertions
Gene Insertion- Gene Insertion
- Gene Insertions
- Insertion, Gene
- Insertions, Gene
Insertion Mutation- Insertion Mutation
- Insertion Mutations
- Mutation, Insertion
- Mutations, Insertion
Insertional Activation- Insertional Activation
- Activation, Insertional
- Activations, Insertional
- Insertional Activations
|
Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Insertional".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Insertional".
This graph shows the total number of publications written about "Mutagenesis, Insertional" by people in this website by year, and whether "Mutagenesis, Insertional" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Mutagenesis, Insertional" by people in Profiles.
-
MuWU: Mutant-seq library analysis and annotation. Bioinformatics. 2022 01 12; 38(3):837-838.
-
Detection of mobile elements insertions for routine clinical diagnostics in targeted sequencing data. Mol Genet Genomic Med. 2021 12; 9(12):e1807.
-
BonnMu: A Sequence-Indexed Resource of Transposon-Induced Maize Mutations for Functional Genomics Studies. Plant Physiol. 2020 10; 184(2):620-631.
-
An insertion mutation in HOXC13 underlies pure hair and nail ectodermal dysplasia with lacrimal duct obstruction. Br J Dermatol. 2018 04; 178(4):e265-e267.
-
Infection as a cause of childhood leukemia: virus detection employing whole genome sequencing. Haematologica. 2017 05; 102(5):e179-e183.
-
Jitterbug: somatic and germline transposon insertion detection at single-nucleotide resolution. BMC Genomics. 2015 Oct 12; 16:768.
-
SWP73 Subunits of Arabidopsis SWI/SNF Chromatin Remodeling Complexes Play Distinct Roles in Leaf and Flower Development. Plant Cell. 2015 Jul; 27(7):1889-906.
-
Arabidopsis thaliana transcription factors bZIP19 and bZIP23 regulate the adaptation to zinc deficiency. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):10296-301.
-
Selective epigenetic control of retrotransposition in Arabidopsis. Nature. 2009 Sep 17; 461(7262):427-30.
-
A reverse genetic approach for generating gene replacement mutants in Ustilago maydis. Mol Genet Genomics. 2004 Sep; 272(2):216-26.
MeSH information
