"Cytokine Receptor gp130" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine receptor that contains extracellular FIBRONECTIN TYPE III DOMAINS which mediate its function through the formation of oligomeric complexes with itself, or with a variety of CYTOKINE RECEPTORS. It does not bind IL-6, but activates JANUS KINASES and STAT3 TRANSCRIPTION FACTOR.
| Descriptor ID |
D050822
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.400.500 D12.776.543.750.705.852.420.560.249 D12.776.543.750.705.852.555.600.500 D12.776.543.750.705.852.583.500 D12.776.543.750.750.400.550.250.500
|
| Concept/Terms |
Cytokine Receptor gp130- Cytokine Receptor gp130
- gp130, Cytokine Receptor
- IL-6 Receptor Signal Transducer gp130
- IL6ST gp130
- gp130 Transducing Protein
- Signal Transducer gp130
- gp130, Signal Transducer
- Antigens, CD130
- gp130 Signal Transducer
- Signal Transducer, gp130
- gp130 IL-6 Family Receptor
- gp130 IL 6 Family Receptor
- IL-6 Family Receptor gp130
- CD130 Antigens
- Interleukin-6 Receptor Subunit Beta
- Interleukin 6 Receptor Subunit Beta
- Signal-Transducing Receptor gp130
- Receptor gp130, Signal-Transducing
- Signal Transducing Receptor gp130
- gp130, Signal-Transducing Receptor
|
Below are MeSH descriptors whose meaning is more general than "Cytokine Receptor gp130".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-6 [D12.776.543.750.705.852.420.400]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.420.400.500]
- Receptors, Interleukin-11 [D12.776.543.750.705.852.420.560]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.420.560.249]
- Receptors, Oncostatin M [D12.776.543.750.705.852.555]
- Receptors, Oncostatin M, Type II [D12.776.543.750.705.852.555.600]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.555.600.500]
- Receptors, OSM-LIF [D12.776.543.750.705.852.583]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.583.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Nerve Growth Factor [D12.776.543.750.750.400.550]
- Receptor, Ciliary Neurotrophic Factor [D12.776.543.750.750.400.550.250]
- Cytokine Receptor gp130 [D12.776.543.750.750.400.550.250.500]
Below are MeSH descriptors whose meaning is more specific than "Cytokine Receptor gp130".
This graph shows the total number of publications written about "Cytokine Receptor gp130" by people in this website by year, and whether "Cytokine Receptor gp130" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2008 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Cytokine Receptor gp130" by people in Profiles.
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Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes. Commun Biol. 2023 04 15; 6(1):418.
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Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling. J Biol Chem. 2018 10 05; 293(40):15359-15369.
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Quantitative protein microarrays for time-resolved measurements of protein phosphorylation. Proteomics. 2008 Nov; 8(21):4603-12.
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Two different epitopes of the signal transducer gp130 sequentially cooperate on IL-6-induced receptor activation. J Immunol. 2000 Dec 15; 165(12):7042-9.
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Different epitopes are required for gp130 activation by interleukin-6, oncostatin M and leukemia inhibitory factor. FEBS Lett. 2000 Feb 25; 468(2-3):120-4.
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Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130. J Immunol. 2000 Jan 01; 164(1):273-82.
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Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes. J Immunol. 1999 Feb 01; 162(3):1480-7.
MeSH information
