"Electron Transport Complex I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein and iron sulfur-containing oxidoreductase complex that catalyzes the conversion of UBIQUINONE to ubiquinol. In MITOCHONDRIA the complex also couples its reaction to the transport of PROTONS across the internal mitochondrial membrane. The NADH DEHYDROGENASE component of the complex can be isolated and is listed as EC 1.6.99.3.
Descriptor ID |
D042967
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MeSH Number(s) |
D05.500.562.249 D08.811.600.250.500.500 D08.811.682.608.504 D12.776.157.427.374.375.863 D12.776.157.530.450.250.875.300 D12.776.331.199.500 D12.776.543.277.500.500 D12.776.543.585.450.250.875.437 D12.776.556.579.374.375.140
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Concept/Terms |
NADH Dehydrogenase (Ubiquinone)- NADH Dehydrogenase (Ubiquinone)
- NADH Dehydrogenase Complex 1
- NADH Dehydrogenase I
- NADH DH I
- Ubiquinone Reductase
- NADH-Coenzyme Q Reductase
- NADH Coenzyme Q Reductase
- NADH-CoQ Reductase
- NADH CoQ Reductase
- NADH-Ubiquinone Oxidoreductase
- NADH Ubiquinone Oxidoreductase
- Oxidoreductase, NADH-Ubiquinone
- NADH-Ubiquinone Reductase
- NADH Ubiquinone Reductase
- Reductase, NADH-Ubiquinone
- Rotenone-Sensitive Mitochondrial NADH-Ubiquinone Oxidoreductase
- Rotenone Sensitive Mitochondrial NADH Ubiquinone Oxidoreductase
- Complex I Dehydrogenase
- Dehydrogenase, Complex I
- NADH Q1 Oxidoreductase
- Oxidoreductase, NADH Q1
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Below are MeSH descriptors whose meaning is more general than "Electron Transport Complex I".
Below are MeSH descriptors whose meaning is more specific than "Electron Transport Complex I".
This graph shows the total number of publications written about "Electron Transport Complex I" by people in this website by year, and whether "Electron Transport Complex I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2000 | 0 | 3 | 3 |
2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
2006 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 1 | 2 |
2013 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Electron Transport Complex I" by people in Profiles.
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A two-step mitochondrial import pathway couples the disulfide relay with matrix complex I biogenesis. J Cell Biol. 2023 07 03; 222(7).
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Impaired complex I repair causes recessive Leber's hereditary optic neuropathy. J Clin Invest. 2021 03 15; 131(6).
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Homozygous missense mutation of NDUFV1 as the cause of infantile bilateral striatal necrosis. Neurogenetics. 2013 Feb; 14(1):85-7.
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A single nucleotide polymorphism associates with the response of muscle ATP synthesis to long-term exercise training in relatives of type 2 diabetic humans. Diabetes Care. 2012 Feb; 35(2):350-7.
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N-acetyl cysteine treatment rescues cognitive deficits induced by mitochondrial dysfunction in G72/G30 transgenic mice. Neuropsychopharmacology. 2011 Oct; 36(11):2233-43.
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Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation. Biochim Biophys Acta. 2010 Jun-Jul; 1797(6-7):1163-70.
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Sites of generation of reactive oxygen species in homogenates of brain tissue determined with the use of respiratory substrates and inhibitors. Biochim Biophys Acta. 2008 Jul-Aug; 1777(7-8):689-95.
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Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6. Neurobiol Dis. 2007 Feb; 25(2):401-11.
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Dopamine transporter SPECT in patients with mitochondrial disorders. J Neurol Neurosurg Psychiatry. 2005 Jan; 76(1):118-20.
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Characterization of superoxide-producing sites in isolated brain mitochondria. J Biol Chem. 2004 Feb 06; 279(6):4127-35.