"Oligonucleotide Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
| Descriptor ID |
D015345
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| MeSH Number(s) |
D13.444.600.601 D27.505.259.750.600.650 D27.720.470.530.600.650
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oligonucleotide Probes".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotide Probes".
This graph shows the total number of publications written about "Oligonucleotide Probes" by people in this website by year, and whether "Oligonucleotide Probes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oligonucleotide Probes" by people in Profiles.
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High-throughput Universal Probe Salmonella Serotyping (UPSS) by nanoPCR. J Microbiol Methods. 2010 Nov; 83(2):217-23.
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Highly specific gene silencing by artificial microRNAs in the unicellular alga Chlamydomonas reinhardtii. Plant J. 2009 Apr; 58(1):165-74.
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Better genechip microarray layouts by combining probe placement and embedding. J Bioinform Comput Biol. 2008 Jun; 6(3):623-41.
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Decoding non-unique oligonucleotide hybridization experiments of targets related by a phylogenetic tree. Bioinformatics. 2006 Jul 15; 22(14):e424-30.
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Fast large scale oligonucleotide selection using the longest common factor approach. J Bioinform Comput Biol. 2003 Jul; 1(2):343-61.
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Rapid large-scale oligonucleotide selection for microarrays. Proc IEEE Comput Soc Bioinform Conf. 2002; 1:54-63.
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Sequence analysis of the MEN I gene in two patients with multiple cutaneous lipomas and endocrine tumors. Horm Metab Res. 2000 Feb; 32(2):76-9.
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Reprogramming of myosin light chain 1/3 expression in muscle heterokaryons. Dev Biol. 1991 May; 145(1):28-39.
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A yeast tRNA precursor containing a pre-mRNA intron is spliced via the pre-mRNA splicing mechanism. EMBO J. 1990 Mar; 9(3):705-9.
MeSH information
