"DNA Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
| Descriptor ID |
D015342
|
| MeSH Number(s) |
D13.444.600.223 D27.505.259.750.600.223 D27.720.470.530.600.223
|
| Concept/Terms |
DNA Probes- DNA Probes
- Probes, DNA
- DNA Hybridization Probes
- Hybridization Probes, DNA
- Probes, DNA Hybridization
|
Below are MeSH descriptors whose meaning is more general than "DNA Probes".
Below are MeSH descriptors whose meaning is more specific than "DNA Probes".
This graph shows the total number of publications written about "DNA Probes" by people in this website by year, and whether "DNA Probes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 3 | 0 | 3 |
| 2004 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA Probes" by people in Profiles.
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High-throughput microarray technology in diagnostics of enterobacteria based on genome-wide probe selection and regression analysis. BMC Genomics. 2010 Oct 21; 11:591.
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Better genechip microarray layouts by combining probe placement and embedding. J Bioinform Comput Biol. 2008 Jun; 6(3):623-41.
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Improving the design of genechip arrays by combining placement and embedding. Comput Syst Bioinformatics Conf. 2007; 6:417-27.
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Optimal robust non-unique probe selection using Integer Linear Programming. Bioinformatics. 2004 Aug 04; 20 Suppl 1:i186-93.
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Mean and variance of the Gibbs free energy of oligonucleotides in the nearest neighbor model under varying conditions. Bioinformatics. 2004 Nov 22; 20(17):2928-33.
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The shortest common supersequence problem in a microarray production setting. Bioinformatics. 2003 Oct; 19 Suppl 2:ii156-61.
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Group testing with DNA chips: generating designs and decoding experiments. Proc IEEE Comput Soc Bioinform Conf. 2003; 2:84-91.
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Fast and sensitive probe selection for DNA chips using jumps in matching statistics. Proc IEEE Comput Soc Bioinform Conf. 2003; 2:57-64.
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A multiple-staining procedure for the detection of different DNA fragments on a single blot. Anal Biochem. 1990 Nov 01; 190(2):254-8.
MeSH information
