"Substantia Nigra" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis.
Descriptor ID |
D013378
|
MeSH Number(s) |
A08.186.211.132.659.413.656
|
Concept/Terms |
Substantia Nigra- Substantia Nigra
- Nigra, Substantia
- Nigras, Substantia
- Substantia Nigras
|
Below are MeSH descriptors whose meaning is more general than "Substantia Nigra".
Below are MeSH descriptors whose meaning is more specific than "Substantia Nigra".
This graph shows the total number of publications written about "Substantia Nigra" by people in this website by year, and whether "Substantia Nigra" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2013 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
2020 | 0 | 2 | 2 |
2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Substantia Nigra" by people in Profiles.
-
Morpho-Functional Changes of Nigral Dopamine Neurons in an a-Synuclein Model of Parkinson's Disease. Mov Disord. 2023 02; 38(2):256-266.
-
Psychosis-Like Behavior and Hyperdopaminergic Dysregulation in Human a-Synuclein BAC Transgenic Rats. Mov Disord. 2021 03; 36(3):716-728.
-
Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration. Brain. 2020 01 01; 143(1):94-111.
-
Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease. Nat Commun. 2019 09 02; 10(1):3945.
-
Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy. Behav Brain Res. 2019 05 02; 363:199-215.
-
Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors. Neurobiol Aging. 2015 Mar; 36(3):1543-58.
-
rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration. Mol Neurodegener. 2013 Nov 25; 8:44.