"alpha-Synuclein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synuclein that is a major component of LEWY BODIES that plays a role in neurodegeneration and neuroprotection.
Descriptor ID |
D051844
|
MeSH Number(s) |
D12.776.631.860.500 D12.776.637.500
|
Concept/Terms |
alpha-Synuclein- alpha-Synuclein
- alpha Synuclein
- Non-AB Component of AD Amyloid Protein
- Non AB Component of AD Amyloid Protein
|
Below are MeSH descriptors whose meaning is more general than "alpha-Synuclein".
Below are MeSH descriptors whose meaning is more specific than "alpha-Synuclein".
This graph shows the total number of publications written about "alpha-Synuclein" by people in this website by year, and whether "alpha-Synuclein" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
2013 | 3 | 0 | 3 |
2014 | 2 | 0 | 2 |
2017 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
2019 | 2 | 1 | 3 |
2020 | 0 | 2 | 2 |
2021 | 1 | 0 | 1 |
2022 | 0 | 2 | 2 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "alpha-Synuclein" by people in Profiles.
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Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease. Mol Neurodegener. 2023 07 04; 18(1):44.
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Intronic enhancers of the human SNCA gene predominantly regulate its expression in brain in vivo. Sci Adv. 2022 11 25; 8(47):eabq6324.
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Morpho-Functional Changes of Nigral Dopamine Neurons in an a-Synuclein Model of Parkinson's Disease. Mov Disord. 2023 02; 38(2):256-266.
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Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function. Sci Rep. 2021 11 09; 11(1):21946.
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Psychosis-Like Behavior and Hyperdopaminergic Dysregulation in Human a-Synuclein BAC Transgenic Rats. Mov Disord. 2021 03; 36(3):716-728.
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Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease. Mov Disord. 2021 02; 36(2):449-459.
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Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease. Nat Commun. 2019 09 02; 10(1):3945.
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Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats. Acta Neuropathol. 2019 10; 138(4):535-550.
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a-Synuclein in Parkinson's disease: causal or bystander? J Neural Transm (Vienna). 2019 07; 126(7):815-840.
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Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy. Behav Brain Res. 2019 05 02; 363:199-215.