"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Descriptor ID |
D003424
|
| MeSH Number(s) |
C06.405.205.731.500 C06.405.469.432.500
|
| Concept/Terms |
Crohn Disease- Crohn Disease
- Crohn's Enteritis
- Regional Enteritis
- Crohn's Disease
- Crohns Disease
- Inflammatory Bowel Disease 1
Ileitis, Terminal- Ileitis, Terminal
- Terminal Ileitis
- Ileitis, Regional
- Regional Ileitides
- Regional Ileitis
|
Below are MeSH descriptors whose meaning is more general than "Crohn Disease".
Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".
This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 2 | 0 | 2 |
| 2012 | 3 | 0 | 3 |
| 2013 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 4 | 0 | 4 |
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Below are the most recent publications written about "Crohn Disease" by people in Profiles.
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Detailed Transcriptional Landscape of Peripheral Blood Points to Increased Neutrophil Activation in Treatment-Na?ve Inflammatory Bowel Disease. J Crohns Colitis. 2022 Aug 04; 16(7):1097-1109.
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Dysbiosis in the Gut Microbiota in Patients with Inflammatory Bowel Disease during Remission. Microbiol Spectr. 2022 06 29; 10(3):e0061622.
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A novel unconventional T cell population enriched in Crohn's disease. Gut. 2022 11; 71(11):2194-2204.
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A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+ T cells and is defective in Crohn?s disease patients. Mucosal Immunol. 2022 03; 15(3):480-490.
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Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in Patients With Active Inflammatory Bowel Disease. Gastroenterology. 2021 06; 160(7):2354-2366.e11.
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Microbial Butyrate Synthesis Indicates Therapeutic Efficacy of Azathioprine in IBD Patients. J Crohns Colitis. 2021 Jan 13; 15(1):88-98.
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Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases. J Crohns Colitis. 2020 Jul 09; 14(6):778-790.
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Cell Specific eQTL Analysis without Sorting Cells. PLoS Genet. 2015 May; 11(5):e1005223.
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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013 Sep; 45(9):984-94.
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Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies. Gastroenterology. 2013 Aug; 145(2):339-47.
MeSH information
