Next Generation Sequencing Competence Network

Next Generation Sequencing Competence Network

e.g. CCGA
(min 2 characters)

Michael Nothnagel

Prof.
University of Köln
Statistical Genetics and Bioinformatics
Weyertal 115b, 50931 Köln, Germany
Köln 50931
+49 221 47896847
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kl?ckner C, Bayat A, Radtke M, M?ller RS, Macnee M, P?rez-Palma E, Br?nger T, Platzer K, Stefanski A, Montanucci L, Collins RL, Talkowski M, Blankenberg D, Lemke JR, Nothnagel M, May P, Lal D. CNV-ClinViewer: enhancing the clinical interpretation of large copy-number variants online. Bioinformatics. 2023 05 04; 39(5). PMID: 37104749; PMCID: PMC10174702.
      Citations: 3     Fields:    Translation:Humans
    2. Ruiz-Ram?rez J, de la Puente M, Xavier C, Ambroa-Conde A, ?lvarez-Dios J, Freire-Aradas A, Mosquera-Miguel A, Ralf A, Amory C, Katsara MA, Khellaf T, Nothnagel M, Cheung EYY, Gross TE, Schneider PM, Uacyisrael J, Oliveira S, Klautau-Guimar?es MDN, Carvalho-Gontijo C, Pospiech E, Branicki W, Parson W, Kayser M, Carracedo A, Lareu MV, Phillips C, VISAGE Consortium. Development and evaluations of the ancestry informative markers of the VISAGE Enhanced Tool for Appearance and Ancestry. Forensic Sci Int Genet. 2023 05; 64:102853. PMID: 36917866.
      Citations: 1     Fields:    Translation:Humans
    3. Schorge S, Zuberi S, Symonds J, Brunklaus A, Traynelis SF, Br?nger T, P?rez-Palma E, Montanucci L, Nothnagel M, M?ller RS, Lemke JR, May P, Lal D. Conserved patterns across ion channels correlate with variant pathogenicity and clinical phenotypes. Brain. 2023 03 01; 146(3):923-934. PMID: 36036558; PMCID: PMC9976975.
      Citations: 5     Fields:    Translation:Humans
    4. Ishorst N, Henschel L, Thieme F, Drichel D, Sivalingam S, Mehrem SL, Fechtner AC, Fazaal J, Welzenbach J, Heimbach A, Maj C, Borisov O, Hausen J, Raff R, Hoischen A, Dixon M, Rada-Iglesias A, Bartusel M, Rojas-Martinez A, Aldhorae K, Braumann B, Kruse T, Kirschneck C, Spanier G, Reutter H, Nowak S, G?lz L, Knapp M, Buness A, Krawitz P, N?then MM, Nothnagel M, Becker T, Ludwig KU, Mangold E. Identification of de novo variants in nonsyndromic cleft lip with/without cleft palate patients with low polygenic risk scores. Mol Genet Genomic Med. 2023 03; 11(3):e2109. PMID: 36468602; PMCID: PMC10009911.
      Citations: 1     Fields:    Translation:Humans
    5. Adesoji OM, Schulz H, May P, Krause R, Nothnagel M, ILAE Consortium on Complex Epilepsies, Lerche H. Benchmarking of univariate pleiotropy detection methods applied to epilepsy. Hum Mutat. 2022 09; 43(9):1314-1332. PMID: 35620985.
      Citations:    Fields:    Translation:Humans
    6. Nothnagel M. Correction to: Towards a fine-scale picture of European genetic diversity. Eur J Hum Genet. 2022 Feb; 30(2):249. PMID: 34408291; PMCID: PMC8821613.
      Citations:    Fields:    
    7. Nothnagel M, Fan G, Guo F, He Y, Hou Y, Hu S, Huang J, Jiang X, Kim W, Kim K, Li C, Li H, Li L, Li S, Li Z, Liang W, Liu C, Lu D, Luo H, Nie S, Shi M, Sun H, Tang J, Wang L, Wang CC, Wang D, Wen SQ, Wu H, Wu W, Xing J, Yan J, Yan S, Yao H, Ye Y, Yun L, Zeng Z, Zha L, Zhang S, Zheng X, Willuweit S, Roewer L. Retraction Note to: Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes. Hum Genet. 2022 01; 141(1):175-176. PMID: 34894272.
      Citations: 1     Fields:    
    8. Krause R, Sander T, Bobbili DR, Nothnagel M, May P, Epi25 Collaborative, Koko M, Lerche H. Distinct gene-set burden patterns underlie common generalized and focal epilepsies. EBioMedicine. 2021 Oct; 72:103588. PMID: 34571366; PMCID: PMC8479647.
      Citations: 4     Fields:    Translation:Humans
    9. Xavier C, Freire-Aradas A, Mosquera-Miguel A, Gross TE, Cheung EYY, Nothnagel M, Parson W, Schneider PM, Kayser M, Lareu MV, Phillips C, de la Puente M, Ruiz-Ram?rez J, Ambroa-Conde A, Pardo-Seco J, ?lvarez-Dios J, Branicki W, Carracedo ?. Development and Evaluation of the Ancestry Informative Marker Panel of the VISAGE Basic Tool. Genes (Basel). 2021 08 22; 12(8). PMID: 34440458; PMCID: PMC8391248.
      Citations: 5     Fields:    Translation:Humans
    10. Gaede KI, Saltini C, Rossman MD, Monos DS, Rosenman KD, Schuler CR, Weston A, Wegner R, Noth R, Zissel G, Schreiber S, Nothnagel M, Frye BC, M?ller-Quernheim J. Analysis of single nucleotide polymorphisms in chronic beryllium disease. Respir Res. 2021 Apr 16; 22(1):107. PMID: 33863318; PMCID: PMC8051053.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    11. Mohseni M, Babanejad M, Booth KT, Jamali P, Jalalvand K, Davarnia B, Ardalani F, Khoshaeen A, Arzhangi S, Ghodratpour F, Beheshtian M, Jahanshad F, Otukesh H, Bahrami F, Seifati SM, Bazazzadegan N, Habibi F, Behravan H, Mirzaei S, Keshavarzi F, Nikzat N, Mehrjoo Z, Thiele H, Nothnagel M, Azaiez H, Smith RJ, Kahrizi K, Najmabadi H. Exome sequencing utility in defining the genetic landscape of hearing loss and novel-gene discovery in Iran. Clin Genet. 2021 07; 100(1):59-78. PMID: 33713422; PMCID: PMC8195868.
      Citations: 2     Fields:    Translation:Humans
    12. Katsara MA, Branicki W, Walsh S, Kayser M, Nothnagel M, VISAGE Consortium. Evaluation of supervised machine-learning methods for predicting appearance traits from DNA. Forensic Sci Int Genet. 2021 07; 53:102507. PMID: 33831816.
      Citations: 3     Fields:    Translation:Humans
    13. Villaescusa P, Nothnagel M, Alvarez-Gila O, M de Pancorbo M, Seidel M, Pinotti T, Gonz?lez-Andrade F, Roewer L. A Y-chromosomal survey of Ecuador's multi-ethnic population reveals new insights into the tri-partite population structure and supports an early Holocene age of the rare Native American founder lineage C3-MPB373. Forensic Sci Int Genet. 2021 03; 51:102427. PMID: 33254102.
      Citations: 1     Fields:    Translation:HumansCells
    14. Katsara MA, Hysi P, Walsh S, Kayser M, Nothnagel M, VISAGE Consortium, Branicki W, Pospiech E. Testing the impact of trait prevalence priors in Bayesian-based genetic prediction modeling of human appearance traits. Forensic Sci Int Genet. 2021 01; 50:102412. PMID: 33260052.
      Citations: 1     Fields:    Translation:Humans
    15. Quach BC, Bray MJ, Gaddis NC, Liu M, Palviainen T, Minica CC, Zellers S, Sherva R, Aliev F, Young KA, Marks JA, Young H, Carnes MU, Guo Y, Waldrop A, Sey NYA, Landi MT, McNeil DW, Farrer LA, Markunas CA, Vink JM, Hottenga JJ, Iacono WG, Kranzler HR, Saccone NL, Neale MC, Madden P, Rietschel M, Marazita ML, McGue M, Won H, Grucza R, Dick DM, Gelernter J, Caporaso NE, Baker TB, Boomsma DI, Kaprio J, Hokanson JE, Vrieze S, Bierut LJ, Johnson EO, Hancock DB, Nothnagel M, Drichel D, Winterer G. Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits. Nat Commun. 2020 11 03; 11(1):5562. PMID: 33144568; PMCID: PMC7642344.
      Citations: 43     Fields:    Translation:Humans
    16. Chen Y, Branicki W, Walsh S, Nothnagel M, Kayser M, Liu F, VISAGE Consortium. The impact of correlations between pigmentation phenotypes and underlying genotypes on genetic prediction of pigmentation traits. Forensic Sci Int Genet. 2021 01; 50:102395. PMID: 33070049.
      Citations: 1     Fields:    Translation:Humans
    17. Kanoungi G, Nothnagel M, Becker T, Drichel D. The exhaustive genomic scan approach, with an application to rare-variant association analysis. Eur J Hum Genet. 2020 09; 28(9):1283-1291. PMID: 32415273; PMCID: PMC7608423.
      Citations: 2     Fields:    Translation:HumansCells
    18. Nothnagel M. Towards a fine-scale picture of European genetic diversity. Eur J Hum Genet. 2020 07; 28(7):851-852. PMID: 32238910; PMCID: PMC7316748.
      Citations:    Fields:    Translation:Humans
    19. Caliebe A, Nothnagel M. Special issue on 'Genetic epidemiology of complex diseases: impact of population history and modelling assumptions'. Hum Genet. 2020 01; 139(1):1-3. PMID: 31664516.
      Citations:    Fields:    Translation:Humans
    20. Zhao L, He Z, Zhang D, Wang GT, Renton AE, Vardarajan BN, Nothnagel M, Goate AM, Mayeux R, Leal SM. A Rare Variant Nonparametric Linkage Method for Nuclear and Extended Pedigrees with Application to Late-Onset Alzheimer Disease via WGS Data. Am J Hum Genet. 2019 10 03; 105(4):822-835. PMID: 31585107; PMCID: PMC6817540.
      Citations: 8     Fields:    Translation:Humans
    21. Mehrjoo Z, Fattahi Z, Beheshtian M, Mohseni M, Poustchi H, Ardalani F, Jalalvand K, Arzhangi S, Mohammadi Z, Khoshbakht S, Najafi F, Nikuei P, Haddadi M, Zohrehvand E, Oladnabi M, Mohammadzadeh A, Jafari MH, Akhtarkhavari T, Gooshki ES, Haghdoost A, Najafipour R, Niestroj LM, Helwing B, Gossmann Y, Toliat MR, Malekzadeh R, Kahrizi K, Najmabadi H, Nothnagel M, N?rnberg P. Distinct genetic variation and heterogeneity of the Iranian population. PLoS Genet. 2019 09; 15(9):e1008385. PMID: 31550250; PMCID: PMC6759149.
      Citations: 18     Fields:    Translation:Humans
    22. Lipinski S, Petersen BS, Barann M, Piecyk A, Tran F, Mayr G, Jentzsch M, Aden K, Stengel ST, Klostermeier UC, Sheth V, Ellinghaus D, Rausch T, Korbel JO, Nothnagel M, Krawczak M, Gilissen C, Veltman JA, Forster M, Forster P, Lee CC, Fritscher-Ravens A, Schreiber S, Franke A, Rosenstiel P. Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2. Cold Spring Harb Mol Case Stud. 2019 02; 5(1). PMID: 30709874; PMCID: PMC6371741.
      Citations: 6     Fields:    Translation:HumansCells
    23. Vidaki A, Kayser M, Nothnagel M. Unsupported claim of significant discrimination between monozygotic twins from multiple pairs based on three age-related DNA methylation markers. Forensic Sci Int Genet. 2019 03; 39:e1-e2. PMID: 30655205.
      Citations:    Fields:    Translation:HumansCells
    24. Katsara MA, Nothnagel M. True colors: A literature review on the spatial distribution of eye and hair pigmentation. Forensic Sci Int Genet. 2019 03; 39:109-118. PMID: 30639910.
      Citations: 5     Fields:    Translation:Humans
    25. Niestroj LM, Du J, Nothnagel M, May P, Palotie A, Daly MJ, Lal D, N?rnberg P, Bl?mcke I. Guideline-based and bioinformatic reassessment of lesion-associated gene and variant pathogenicity in focal human epilepsies. Epilepsia. 2018 11; 59(11):2145-2152. PMID: 30341947.
      Citations: 4     Fields:    Translation:Humans
    26. Strathmann EA, Peters M, Hosseinibarkooie S, Rigo FW, Bennett CF, Zaworski PG, Chen KS, Nothnagel M, Wirth B. Evaluation of potential effects of Plastin 3 overexpression and low-dose SMN-antisense oligonucleotides on putative biomarkers in spinal muscular atrophy mice. PLoS One. 2018; 13(9):e0203398. PMID: 30188931; PMCID: PMC6126849.
      Citations: 8     Fields:    Translation:Animals
    27. Strnad P, Buch S, Hamesch K, Fischer J, Rosendahl J, Schmelz R, Brueckner S, Brosch M, Heimes CV, Woditsch V, Scholten D, Nischalke HD, Janciauskiene S, Mandorfer M, Trauner M, Way MJ, McQuillin A, Reichert MC, Krawczyk M, Casper M, Lammert F, Braun F, Hinz S, Burmeister G, Teufel A, Feldman A, Schattenberg JM, Bantel H, Pathil A, Demir M, Kluwe J, Boettler T, Ridinger M, Wodarz N, Soyka M, Rietschel M, Kiefer F, Weber T, Marhenke S, Vogel A, Hinrichsen H, Canbay A, Schlattjan M, Sosnowsky K, Sarrazin C, von Felden J, Geier A, Deltenre P, Sipos B, Schafmayer C, Nothnagel M, Aigner E, Datz C, Stickel F, Morgan MY, Hampe J, Berg T, Trautwein C, von Sch?nfels W, Hellerbrand C. Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis. Gut. 2019 06; 68(6):1099-1107. PMID: 30068662.
      Citations: 37     Fields:    Translation:Humans
    28. May P, Girard S, Harrer M, Bobbili DR, Schubert J, Wolking S, Becker F, Lachance-Touchette P, Meloche C, Gravel M, Niturad CE, Knaus J, De Kovel C, Toliat M, Polvi A, Iacomino M, Marini C, Thiele H, Jabbari K, Ruppert AK, Jurkowski W, Lal D, Rusconi R, Terragni B, Coombs ID, Reid CA, Striano P, Caglayan H, Siren A, Everett K, Hjalgrim H, Muhle H, Helbig I, Kunz WS, Weber YG, Weckhuysen S, Jonghe P, Sisodiya SM, Nabbout R, Franceschetti S, Coppola A, Vari MS, Baykan B, Ozbek U, Bebek N, Klein KM, Rosenow F, Nguyen DK, Carmant L, Lortie A, Desbiens R, Sills GJ, Auce P, Francis B, Johnson MR, Marson AG, Berghuis B, Sander JW, Avbersek A, McCormack M, Cavalleri GL, Delanty N, Depondt C, Krenn M, Zimprich F, Peter S, Nikanorova M, Kraaij R, van Rooij J, Balling R, Ikram MA, Avanzini G, Schorge S, Petrou S, Mantegazza M, Sander T, LeGuern E, Serratosa JM, Koeleman BPC, Palotie A, Lehesjoki AE, Nothnagel M, Maljevic S, Zara F, Cossette P, Krause R, Lerche H, Epicure Consortium, EuroEPINOMICS CoGIE Consortium, EpiPGX Consortium, Guerrero-L?pez R, Baulac S, Altm?ller J, Cest?le S, M?ller RS, Kasteleijn-Nolst Trenit? D, Dubeau F, Cl?ment JF, Cieuta-Walti C, Uitterlinden AG, N?rnberg P. Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study. Lancet Neurol. 2018 08; 17(8):699-708. PMID: 30033060.
      Citations: 31     Fields:    Translation:Humans
    29. Krause-Kyora B, Nutsua M, Boehme L, Pedersen DD, Kornell SC, Drichel D, Bonazzi M, Tarp P, Susat J, Bosse E, Franke A, Wittig M, Caliebe A, Nothnagel M, Schreiber S, Boldsen JL, Nebel A, Pierini F, M?bus L, Willburger B, Schmidt AH, Sauter J, Lenz TL. Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans. Nat Commun. 2018 05 01; 9(1):1569. PMID: 29717136; PMCID: PMC5931558.
      Citations: 33     Fields:    Translation:HumansCells
    30. Engel C, Nothnagel M, Ernst C, Hahnen E, Weber J, Schmutzler RK, Hauke J. Performance of in silico prediction tools for the classification of rare BRCA1/2 missense variants in clinical diagnostics. BMC Med Genomics. 2018 03 27; 11(1):35. PMID: 29580235; PMCID: PMC5870501.
      Citations: 46     Fields:    Translation:Humans
    31. Kanoungi G, Nothnagel M. Pathway-induced allelic spectra of diseases in the presence of strong genetic effects. Hum Genet. 2018 Mar; 137(3):215-230. PMID: 29423653.
      Citations: 1     Fields:    Translation:HumansCells
    32. Bobbili DR, Lal D, May P, Reinthaler EM, Jabbari K, Thiele H, Nothnagel M, Jurkowski W, Feucht M, Zimprich F, Krause R, Neubauer BA, Feucht M, Neophytou B, Gruber-Sedlmayr U, Haberlandt E, Ronen GM, Sander T, Krause R, May P, Balling R, Neubauer BA, EUROEPINOMICS COGIE Consortium, N?rnberg P, Lerche H, Steinb?ck H, Geldner J, Altm?ller J. Exome-wide analysis of mutational burden in patients with typical and atypical Rolandic epilepsy. Eur J Hum Genet. 2018 02; 26(2):258-264. PMID: 29358611; PMCID: PMC5839048.
      Citations: 10     Fields:    Translation:Humans
    33. Nygaard M, Lieb W, Drichel D, Christiansen L, Christensen K, Nothnagel M, Rosenstiel P, Franke A, Flachsbart F, Dose J, Gentschew L, Geismann C, Caliebe A, Knecht C, Badarinarayan N, ElSharawy A, May S, Luzius A, Torres GG, Jentzsch M, Forster M, H?sler R, Pallauf K, Derbois C, Galan P, Arlt A, Till A, Krause-Kyora B, Rimbach G, Blanch? H, Deleuze JF, Schreiber S, Sebens S, Nebel A. Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3. Nat Commun. 2018 01 17; 9(1):320. PMID: 29339726; PMCID: PMC5770466.
      Citations:    Fields:    
    34. Asadollahi R, Strauss JE, Zenker M, Beuing O, Edvardson S, Elpeleg O, Joset P, Niedrist D, Otte C, Oneda B, Boonsawat P, Azzarello-Burri S, Bartholdi D, Papik M, Zweier M, Haas C, Baumer A, Boltshauser E, Steindl K, Nothnagel M, Schinzel A, Stoeckli ET, Rauch A, Strom TM, Ekici AB. Clinical and experimental evidence suggest a link between KIF7 and C5orf42-related ciliopathies through Sonic Hedgehog signaling. Eur J Hum Genet. 2018 02; 26(2):197-209. PMID: 29321670; PMCID: PMC5839020.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    35. Nygaard M, Lieb W, Drichel D, Christiansen L, Christensen K, Nothnagel M, Flachsbart F, Dose J, Gentschew L, Geismann C, Caliebe A, Knecht C, Badarinarayan N, ElSharawy A, May S, Luzius A, Torres GG, Jentzsch M, Forster M, H?sler R, Pallauf K, Derbois C, Galan P, Arlt A, Till A, Krause-Kyora B, Rimbach G, Blanch? H, Deleuze JF, Rosenstiel P, Schreiber S, Franke A, Sebens S, Nebel A. Identification and characterization of two functional variants in the human longevity gene FOXO3. Nat Commun. 2017 12 12; 8(1):2063. PMID: 29234056; PMCID: PMC5727304.
      Citations: 43     Fields:    Translation:Humans
    36. Ng M, Thakkar D, Southam L, Werker P, Ophoff R, Franke A, Espirito-Santo AI, Izadi D, Nanchahal J, Zeggini E, Furniss D, Becker K, Nothnagel M, N?rnberg P, Hennies HC. A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis. Am J Hum Genet. 2017 Sep 07; 101(3):417-427. PMID: 28886342; PMCID: PMC5591021.
      Citations: 28     Fields:    Translation:HumansCells
    37. Koch M, Freitag-Wolf S, Schlesinger S, Borggrefe J, Hov JR, Jensen MK, Pick J, Markus MRP, Jacobs G, Siegert S, Illig T, Nothnagel M, Karlsen TH, Schreiber S, Franke A, Krawczak M, Lieb W, H?pfner T, Artati A, Kastenm?ller G, R?misch-Margl W, Adamski J, N?thlings U. Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample. Eur J Clin Nutr. 2017 08; 71(8):995-1001. PMID: 28378853.
      Citations: 14     Fields:    Translation:Humans
    38. Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR, Hecker J, Javed A, Chew EG, Pechlivanis S, Drichel D, Heng XT, Del Rosario RC, Fier HL, Paus R, Rueedi R, Galesloot TE, Moebus S, Anhalt T, Prabhakar S, Li R, Kanoni S, Papanikolaou G, Deloukas P, Philpott MP, Spector TD, Vollenweider P, Kiemeney LA, Dedoussis G, Richards JB, Nothnagel M, Martin NG, Becker T, Hinds DA, Kutalik Z, Waeber G, N?then MM. Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness. Nat Commun. 2017 03 08; 8:14694. PMID: 28272467; PMCID: PMC5344973.
      Citations: 23     Fields:    Translation:HumansCells
    39. Kanoungi G, Nothnagel M, N?rnberg P. Securing the use of existing sample collections for future human genetic research. Eur J Hum Genet. 2017 05; 25(5):522-529. PMID: 28145429; PMCID: PMC5437900.
      Citations:    Fields:    Translation:Humans
    40. Nothnagel M, Fan G, Guo F, He Y, Hou Y, Hu S, Huang J, Jiang X, Kim W, Kim K, Li C, Li H, Li L, Li S, Li Z, Liang W, Liu C, Lu D, Luo H, Nie S, Shi M, Sun H, Tang J, Wang L, Wang CC, Wang D, Wen SQ, Wu H, Wu W, Xing J, Yan J, Yan S, Yao H, Ye Y, Yun L, Zeng Z, Zha L, Zhang S, Zheng X, Willuweit S, Roewer L. Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes. Hum Genet. 2017 05; 136(5):485-497. PMID: 28138773.
      Citations: 21     Fields:    Translation:HumansCells
    41. Seemanova E, Vejvalka J, Jarolim P, Seeman P, Chrzanowska KH, Resnick I, Kremensky I, Hoffmann K, Ghani M, Baric I, Tekin M, Kovacs P, Krawczak M, Varon R, Digweed M, Saar K, Dutrannoy V, Karbasiyan M, Reis A, Sperling K, Nothnagel M. The Slavic NBN Founder Mutation: A Role for Reproductive Fitness? PLoS One. 2016; 11(12):e0167984. PMID: 27936167; PMCID: PMC5148078.
      Citations: 9     Fields:    Translation:HumansCells
    42. Becker K, Siegert S, Toliat MR, Du J, Casper R, Dolmans GH, Werker PM, Tinschert S, Franke A, Nothnagel M, Hennies HC, German Dupuytren Study Group, Gieger C, Strauch K, N?rnberg P. Meta-Analysis of Genome-Wide Association Studies and Network Analysis-Based Integration with Gene Expression Data Identify New Suggestive Loci and Unravel a Wnt-Centric Network Associated with Dupuytren's Disease. PLoS One. 2016; 11(7):e0158101. PMID: 27467239; PMCID: PMC4965170.
      Citations: 12     Fields:    Translation:Humans
    43. Diegoli TM, Rohde H, Borowski S, Krawczak M, Coble MD, Nothnagel M. Genetic mapping of 15 human X chromosomal forensic short tandem repeat (STR) loci by means of multi-core parallelization. Forensic Sci Int Genet. 2016 11; 25:39-44. PMID: 27497644.
      Citations: 5     Fields:    Translation:HumansCells
    44. Gardella E, Lemke JR, Larsen LH, Eiberg H, Nothnagel M, Thiele H, Syrbe S, Merkenschlager A, Bast T, Steinhoff B, Mang Y, Gellert P, Heron SE, Dibbens LM, Weckhuysen S, Dahl HA, Tommerup N, Hjalgrim H, Becker F, M?ller RS, Schubert J, Altm?ller J, N?rnberg P, Bakke M?ller L, Biskup S, Lerche H, Beniczky S, Weber YG. Benign infantile seizures and paroxysmal dyskinesia caused by an SCN8A mutation. Ann Neurol. 2016 Mar; 79(3):428-36. PMID: 26677014.
      Citations: 53     Fields:    Translation:Humans
    45. Lal D, Neubauer BA, Toliat MR, Thiele H, Kamrath C, Sander T, Hahn A, Nothnagel M, Altm?ller J, N?rnberg P, Sch?nzer A. Increased Probability of Co-Occurrence of Two Rare Diseases in Consanguineous Families and Resolution of a Complex Phenotype by Next Generation Sequencing. PLoS One. 2016; 11(1):e0146040. PMID: 26789268; PMCID: PMC4720433.
      Citations: 17     Fields:    Translation:Humans
    46. Buch S, Stickel F, Way M, Herrmann A, Nischalke HD, Brosch M, Rosendahl J, Berg T, Ridinger M, Rietschel M, McQuillin A, Frank J, Kiefer F, Schreiber S, Lieb W, Soyka M, Semmo N, Aigner E, Datz C, Schmelz R, Zeissig S, Stephan AM, Wodarz N, Sarrazin C, Lammert F, Lerch MM, Mayerle J, Schafmayer C, Cichon S, Nothnagel M, Ellinghaus D, Huse K, Franke A, Zopf S, Hellerbrand C, Morgan MY, Hampe J, Tr?po E, Br?ckner S, Devi?re J, Clumeck N, Gustot T, Deltenre P, V?lzke H, Eyer F, N?then MM, Moreno C, Franchimont D. A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. Nat Genet. 2015 Dec; 47(12):1443-8. PMID: 26482880.
      Citations: 214     Fields:    Translation:Humans
    47. Abdallah AT, Fischer M, Nothnagel M, Frommolt P, N?rnberg P. CoNCoS: copy number estimation in cancer with controlled support. J Bioinform Comput Biol. 2015 Oct; 13(5):1550027. PMID: 26449175.
      Citations: 1     Fields:    Translation:Humans
    48. Nutsua ME, Fischer A, Nebel A, Hofmann S, Schreiber S, Krawczak M, Nothnagel M. Family-Based Benchmarking of Copy Number Variation Detection Software. PLoS One. 2015; 10(7):e0133465. PMID: 26197066; PMCID: PMC4510559.
      Citations: 5     Fields:    Translation:Humans
    49. Siegert S, Wolf A, Cooper DN, Krawczak M, Nothnagel M. Mutations Causing Complex Disease May under Certain Circumstances Be Protective in an Epidemiological Sense. PLoS One. 2015; 10(7):e0132150. PMID: 26161957; PMCID: PMC4498598.
      Citations: 1     Fields:    Translation:Humans
    50. Reinthaler EM, Dejanovic B, Lal D, Merkler Y, Pittrich DA, Hotzy C, Feucht M, Gruber-Sedlmayr U, Ronen GM, Neophytou B, Haberlandt E, Muhle H, Ikram MA, van Duijn CM, Uitterlinden AG, Hofman A, Kawalia A, Toliat MR, EuroEPINOMICS Consortium, Nothnagel M, Thiele H, Sander T, Neubauer BA, Zimprich F, Semtner M, Reinhold A, Steinb?ck H, Geldner J, Altm?ller J, N?rnberg P, Lerche H, Meier JC, Schwarz G. Rare variants in ?-aminobutyric acid type A receptor genes in rolandic epilepsy and related syndromes. Ann Neurol. 2015 Jun; 77(6):972-86. PMID: 25726841.
      Citations: 30     Fields:    Translation:HumansCells
    51. Syrbe S, Maher B, Hernandez-Hernandez L, Caglayan HS, Arslan M, Nothnagel M, May P, Krause R, Mullis PE, Linnankivi T, Sterbova K, Craiu DC, Hoffman-Zacharska D, Korff CM, Steinlin M, Gallati S, Bertsche A, Bernhard MK, Merkenschlager A, Kiess W, EuroEPINOMICS RES consortium, Gonzalez M, Palotie A, Suls A, De Jonghe P, Helbig I, Sisodiya SM, Weckhuysen S, Lemke JR, Hedrich UBS, Riesch E, Dj?mi? T, M?ller S, M?ller RS, Synofzik M, Serratosa JM, L?ffler H, Detert K, Dorn T, Vogt H, Kr?mer G, Sch?ls L, Lehesjoki AE, Weber YG, Z?chner S, Biskup S, Wolff M, Maljevic S, Sch?le R, Lerche H. De novo loss- or gain-of-function mutations in KCNA2 cause epileptic encephalopathy. Nat Genet. 2015 Apr; 47(4):393-399. PMID: 25751627; PMCID: PMC4380508.
      Citations: 105     Fields:    Translation:HumansCells
    52. Siegert S, Nothnagel M, Roewer L. Shannon's equivocation for forensic Y-STR marker selection. Forensic Sci Int Genet. 2015 May; 16:216-225. PMID: 25682312.
      Citations: 6     Fields:    Translation:HumansCells
    53. Siegert S, Salazar R, Angustia SM, Santos LH, Ayub Q, Wei W, Xue Y, Tyler-Smith C, Bafalluy MB, Ballard D, Court DS, Barrantes X, Berger B, Parson W, Davis C, Budowle B, Burri H, Borer U, Koller C, Chamoun WT, Coble MD, Hill CR, Corach D, Caputo M, D'Amato ME, Davison S, Decorte R, Larmuseau MH, Ottoni C, Rickards O, Lu D, Jiang C, Dobosz T, Jonkisz A, Frank WE, Furac I, Gehrig C, Castella V, Grskovic B, Hadzic G, Drobnic K, Honda K, Hou Y, Zhou D, Li Y, Hu S, Chen S, Jakovski Z, Ilievska T, de Knijff P, Kraaijenbrink T, Kondili A, Miniati P, Vouropoulou M, Kovacevic L, Marjanovic D, Mansour I, Al-Azem M, Andari AE, Moreira H, Mizuno N, Iwashima Y, Neto RS, Nie S, Wang X, Cheng B, Olofsson JK, Morling N, Pamjav H, Volgyi A, Barany G, Pawlowski R, Maciejewska A, Pelotti S, Pepinski W, Abreu-Glowacka M, Piglionica M, Baldassarra SL, Ploski R, Konarzewska M, Jastrzebska E, Robino C, Sajantila A, Palo JU, Guevara E, Salvador J, Ungria MC, Saukko P, Schneider PM, Sirker M, Shin KJ, Oh YN, Skitsa I, Ampati A, Smith TG, Stenzl V, Capal T, Wetton JH, Gwynne GM, Jobling MA, Whittle MR, Sumita DR, Wolanska-Nowak P, Yong RY, Krawczak M, Nothnagel M, Purps J, Willuweit S, Nagy M, Alves C, Anslinger K, Bayer B, Mart?nez-Jarreta B, Egyed B, Balitzki B, Tschumi S, B??ler G, Wiest T, Niederst?tter H, Carvalho EF, Domingues PM, Haas C, Wobst J, Immel UD, Lessig R, Klann AE, Garc?a CC, Lindner I, Marino M, Furfuro S, Locarno L, Mart?n P, Luque GM, Alonso A, Miranda LS, Nogueira TL, Silva R, Nastainczyk-Wulf M, Edelmann J, Kohl M, N??ez C, Pancorbo MM, Onofri V, Tagliabracci A, Phillips C, C?rdenas J, Rey-Gonzalez D, Salas A, Brisighelli F, Capelli C, Toscanini U, Piccinini A, Rodriguez JJ, Schmidt U, Schlauderer N, Calvit LS, Tillmar A, Nilsson H, Turrina S, De Leo D, Verzeletti A, Cortellini V, Roewer L. A global analysis of Y-chromosomal haplotype diversity for 23 STR loci. Forensic Sci Int Genet. 2014 Sep; 12:12-23. PMID: 24854874; PMCID: PMC4127773.
      Citations: 69     Fields:    Translation:HumansCells
    54. Stickel F, Buch S, Zoller H, Hultcrantz R, Gallati S, Finkenstedt A, Stadlmayr A, Aigner E, Sahinbegovic E, Sarrazin C, Schafmayer C, Braun F, Erhart W, Nothnagel M, Lerch MM, Mayerle J, Kratzer W, Boehm BO, D'Amato M, Torkvist L, Stal P, Arlt A, Franke A, Becker T, Krawczak M, Zwerina J, Berg T, Hinrichsen H, Krones E, Dejaco C, Strasser M, Datz C, Hampe J, ?sterreicher C, V?lzke H, Schaller A, Sipos B. Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis. Hum Mol Genet. 2014 Jul 15; 23(14):3883-90. PMID: 24556216.
      Citations: 22     Fields:    Translation:Humans
    55. Siegert S, Yu Z, Wang-Sattler R, Illig T, Adamski J, Hampe J, Nikolaus S, Schreiber S, Krawczak M, Nothnagel M, N?thlings U. Diagnosing fatty liver disease: a comparative evaluation of metabolic markers, phenotypes, genotypes and established biomarkers. PLoS One. 2013; 8(10):e76813. PMID: 24130792; PMCID: PMC3793954.
      Citations: 7     Fields:    Translation:Humans
    56. von Kampen O, Patsenker E, Stickel F, Schniewind B, Hinz S, Ahrens M, Balschun K, Egberts JH, Richter K, Landrock A, Sipos B, Will O, Huebbe P, Schreiber S, Nothnagel M, Rimbach G, Becker T, Hampe J, Schafmayer C, von Sch?nfels W, R?cken C. Metabolic signature of electrosurgical liver dissection. PLoS One. 2013; 8(9):e72022. PMID: 24058442; PMCID: PMC3772850.
      Citations:    Fields:    Translation:HumansCells
    57. Lemke JR, Lal D, Reinthaler EM, Steiner I, Nothnagel M, Alber M, Geider K, Laube B, Schwake M, Finsterwalder K, Franke A, Schilhabel M, Muhle H, Boor R, Van Paesschen W, Caraballo R, Fejerman N, Weckhuysen S, De Jonghe P, Larsen J, Hjalgrim H, Addis L, Tang S, Hughes E, Pal DK, Veri K, Vaher U, Talvik T, Dimova P, Linnankivi T, Lehesjoki AE, Ruf S, Wolff M, Buerki S, Wohlrab G, Kroell J, Datta AN, Fiedler B, Kurlemann G, Kluger G, Hahn A, Haberlandt DE, Kutzer C, Becker F, Weber YG, Feucht M, Neophythou B, Ronen GM, Gruber-Sedlmayr U, Geldner J, Harvey RJ, Hoffmann P, Herms S, Toliat MR, Thiele H, Wilhelm C, Stephani U, Helbig I, Lerche H, Zimprich F, Neubauer BA, Biskup S, von Spiczak S, J?hn JA, M?ller RS, Guerrero L?pez R, Serratosa JM, Sperner J, Steinb?ck H, Altm?ller J, N?rnberg P. Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes. Nat Genet. 2013 Sep; 45(9):1067-72. PMID: 23933819.
      Citations: 162     Fields:    Translation:HumansCells
    58. Ellinghaus D, Zhang H, Zeissig S, Lipinski S, Till A, Jiang T, Bromberg Y, Ellinghaus E, Keller A, Rivas MA, Skieceviciene J, Doncheva NT, Liu X, Liu Q, Jiang F, Forster M, Mayr G, Albrecht M, Boehm BO, Goodall J, Berzuini CR, Lee J, Andersen V, Vogel U, Kupcinskas L, Kayser M, Krawczak M, Nikolaus S, Weersma RK, Ponsioen CY, Sans M, Wijmenga C, Strachan DP, McArdle WL, Rutgeerts P, Sanderson JD, Mathew CG, Vatn MH, Wang J, Duerr RH, Brand S, Winkelmann J, Illig T, Latiano A, Annese V, Halfvarson J, D'Amato M, Daly MJ, Nothnagel M, Karlsen TH, Subramani S, Rosenstiel P, Schreiber S, Parkes M, Franke A, Stade B, H?sler R, Vermeire S, N?then MM, B?ning C, Glas J. Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies. Gastroenterology. 2013 Aug; 145(2):339-47. PMID: 23624108; PMCID: PMC3753067.
      Citations: 89     Fields:    Translation:Humans
    59. Schaefer AS, Bochenek G, Manke T, Nothnagel M, Graetz C, Thien A, Jockel-Schneider Y, Harks I, Staufenbiel I, Wijmenga C, Guzeldemir-Akcakanat E, Cine N, Folwaczny M, Noack B, Meyle J, Eickholz P, Trombelli L, Scapoli C, Nohutcu R, Bruckmann C, Doerfer C, Loos BG, Schreiber S, Eberhard J, Jepsen S. Validation of reported genetic risk factors for periodontitis in a large-scale replication study. J Clin Periodontol. 2013 Jun; 40(6):563-72. PMID: 23587006.
      Citations: 26     Fields:    Translation:HumansCells
    60. Nothnagel M, Gomes V, Corach D, Sala A, Alechine E, Palha T, Santos N, Ribeiro-Dos-Santos A, Geppert M, Willuweit S, Nagy M, Zweynert S, Baeta M, Fagundes de Carvalho E, da Silva DA, Lopez Parra AM, Arroyo-Pardo E, Toscanini U, Borjas L, Barletta C, Ewart E, Santos S, Krawczak M, Roewer L, Gusm?o L, Gonz?lez M, N??ez C, Mart?nez-Jarreta B, Gonz?lez-Andrade F, Builes JJ, Turb?n D. Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans. PLoS Genet. 2013 Apr; 9(4):e1003460. PMID: 23593040; PMCID: PMC3623769.
      Citations: 41     Fields:    Translation:HumansCells
    61. Giatrakos S, Huse K, Kanni T, Tzanetakou V, Kramer M, Grech I, Papadavid E, Katoulis A, Stavrianeas N, Nothnagel M, Platzer M, Bauer M, Giamarellos-Bourboulis EJ. Haplotypes of IL-12R?1 impact on the clinical phenotype of hidradenitis suppurativa. Cytokine. 2013 May; 62(2):297-301. PMID: 23557799.
      Citations: 12     Fields:    Translation:HumansCells
    62. von Kampen O, Buch S, Nothnagel M, Azocar L, Molina H, Brosch M, Erhart W, Egberts J, Seeger M, Arlt A, Balschun T, Franke A, Lerch MM, Mayerle J, Kratzer W, Boehm BO, Huse K, Schniewind B, Tiemann K, Jiang ZY, Han TQ, Mittal B, Srivastava A, Fenger M, Schirin-Sokhan R, Wittenburg H, Stumvoll M, Kalthoff H, Lammert F, Puschel K, Becker T, Schreiber S, Platzer M, Krawczak M, Miquel JF, Schafmayer C, Hampe J, von Sch?nfels W, J?rgensen T, T?njes A, Tepel J, V?lzke H. Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus. Hepatology. 2013 Jun; 57(6):2407-17. PMID: 22898925.
      Citations: 35     Fields:    Translation:HumansCells
    63. Taudien S, Kuss O, Groth M, Huse K, Kluttig A, Wolf A, Nothnagel M, Rosenstiel P, Greiser KH, Werdan K, Krawczak M, Pilarsky C, Platzer M, G?bel G, Gr?tzmann R. Association studies of the copy-number variable ?-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis. BMC Res Notes. 2012 Nov 13; 5:629. PMID: 23148552; PMCID: PMC3532138.
      Citations: 6     Fields:    Translation:HumansCells
    64. Siegert S, Hampe J, Schafmayer C, Egberts JH, Chen B, Hemminki K, Franke A, Nothnagel M, Krawczak M, von Sch?nfels W, F?rsti A, Lascorz J, N?thlings U. Genome-wide investigation of gene-environment interactions in colorectal cancer. Hum Genet. 2013 Feb; 132(2):219-31. PMID: 23114982.
      Citations: 29     Fields:    Translation:Humans
    65. Brand J, Nothnagel M, Arlt A, Neser F, Schreiber S, Zeitz M, Hampe J, J?rgensen C, Habeck JO, St?lzel U. Prognostic relevance of gastric cancer staging by endoscopic ultrasound. Surg Endosc. 2013 Apr; 27(4):1124-9. PMID: 23052533.
      Citations: 9     Fields:    Translation:Humans
    66. Hofmann S, Fischer A, Nothnagel M, Jacobs G, Schmid B, Wittig M, Franke A, Gaede KI, Petrek M, Mrazek F, Pabst S, Grunewald J, Ronninger M, Eklund A, Rosenstiel P, Zissel G, Schreiber S, Sch?rmann M, Groh? C, H?hne K, M?ller-Quernheim J. Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis. Eur Respir J. 2013 Apr; 41(4):888-900. PMID: 22936702.
      Citations: 18     Fields:    Translation:HumansCells
    67. Fritsch C, Herrmann A, Nothnagel M, Szafranski K, Huse K, Schumann F, Schreiber S, Platzer M, Krawczak M, Hampe J, Brosch M. Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting. Genome Res. 2012 Nov; 22(11):2208-18. PMID: 22879431; PMCID: PMC3483550.
      Citations: 117     Fields:    Translation:HumansCells
    68. Fischer A, Schmid B, Ellinghaus D, Nothnagel M, Gaede KI, Lipinski S, Rosenstiel P, Zissel G, Petrek M, Kolek V, Pabst S, Grunewald J, Ronninger M, Eklund A, Padyukov L, Gieger C, Wichmann HE, Nebel A, Franke A, Hofmann S, Schreiber S, Sch?rmann M, H?hne K, Groh? C, M?ller-Quernheim J. A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1. Am J Respir Crit Care Med. 2012 Nov 01; 186(9):877-85. PMID: 22837380.
      Citations: 25     Fields:    Translation:Humans
    69. Thier S, Lorenz D, Nothnagel M, Poremba C, Papengut F, Appenzeller S, Paschen S, Hofschulte F, Hussl AC, Hering S, Poewe W, Asmus F, Gasser T, Christensen K, Nebel A, Schreiber S, Klebe S, Sch?ls L, Deuschl G, Kuhlenb?umer G. Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor. Neurology. 2012 Jul 17; 79(3):243-8. PMID: 22764253; PMCID: PMC3398434.
      Citations: 51     Fields:    Translation:Humans
    70. Ellinghaus D, Ellinghaus E, Nair RP, Stuart PE, Metspalu A, Debrus S, Raelson JV, Tejasvi T, Belouchi M, West SL, Barker JN, Balschun T, Palmieri O, Annese V, Gieger C, Wichmann HE, Kabesch M, Trembath RC, Mathew CG, Weidinger S, Nikolaus S, Schreiber S, Elder JT, Weichenthal M, Nothnagel M, Franke A, Esko T, K?ks S, Kingo K, Abecasis GR. Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci. Am J Hum Genet. 2012 Apr 06; 90(4):636-47. PMID: 22482804; PMCID: PMC3322238.
      Citations: 147     Fields:    Translation:Humans
    71. Szibor R, Vollrath O, Augustin C, Edelmann J, Geppert M, Vennemann M, Hou Y, Immel UD, Inturri S, Luo H, Lutz-Bonengel S, Robino C, Roewer L, Rolf B, Sanft J, Shin KJ, Sim JE, Wiegand P, Winkler C, Krawczak M, Hering S, Nothnagel M, Alves C, Gusm?o L. Collaborative genetic mapping of 12 forensic short tandem repeat (STR) loci on the human X chromosome. Forensic Sci Int Genet. 2012 Dec; 6(6):778-84. PMID: 22459949.
      Citations: 18     Fields:    Translation:HumansCells
    72. Quednow BB, Mobascher A, Nothnagel M, Musso F, Savary N, Petrovsky N, Frommann I, Lennertz L, Spreckelmeyer KN, Wienker TF, Dahmen N, Thuerauf N, Clepce M, Kiefer F, Majic T, Maier W, Diaz-Lacava A, Toliat MR, Thiele H, Wagner M, Winterer G, Brinkmeyer J, Gr?nder G, M?ssner R, Gallinat J, N?rnberg P. Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating. Proc Natl Acad Sci U S A. 2012 Apr 17; 109(16):6271-6. PMID: 22451930; PMCID: PMC3341057.
      Citations: 29     Fields:    Translation:Humans
    73. Helbig KL, Nothnagel M, Hampe J, Balschun T, Nikolaus S, Schreiber S, Franke A, N?thlings U. A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology. BMC Med Genet. 2012 Mar 14; 13:14. PMID: 22416979; PMCID: PMC3314543.
      Citations: 12     Fields:    Translation:Humans
    74. Brosch M, Ahrens M, Nothnagel M, Krawczak M, Laudes M, Sipos B, Becker T, Schreiber S, Schafmayer C, Hampe J, von Sch?nfels W, R?cken C. SFRS10--a splicing factor gene reduced in human obesity? Cell Metab. 2012 Mar 07; 15(3):265-6; author reply 267-9. PMID: 22405059.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    75. Rubin D, Helwig U, Pfeuffer M, Auinger A, Ruether A, Matusch D, Darabaneanu S, Freitag-Wolf S, Nothnagel M, Schreiber S, Schrezenmeir J. The effect of FABP2 promoter haplotype on response to a diet with medium-chain triacylglycerols. Genes Nutr. 2012 Jul; 7(3):437-45. PMID: 22270906; PMCID: PMC3380186.
      Citations: 1     
    76. Richter GM, Graetz C, Pohler P, Nothnagel M, Dommisch H, Laine ML, Folwaczny M, Noack B, Eickholz P, Groessner-Schreiber B, Loos BG, Schreiber S, Schaefer AS, Jepsen S. Common genetic risk variants of TLR2 are not associated with periodontitis in large European case-control populations. J Clin Periodontol. 2012 Apr; 39(4):315-22. PMID: 22251071.
      Citations: 2     Fields:    Translation:Humans
    77. Dolmans GH, Werker PM, Hennies HC, Furniss D, Festen EA, Franke L, Becker K, van der Vlies P, Wolffenbuttel BH, Tinschert S, Toliat MR, Nothnagel M, Franke A, Klopp N, Wichmann HE, Giele H, Ophoff RA, Wijmenga C, Dutch Dupuytren Study Group, German Dupuytren Study Group, LifeLines Cohort Study, BSSH-GODD Consortium, N?rnberg P. Wnt signaling and Dupuytren's disease. N Engl J Med. 2011 Jul 28; 365(4):307-17. PMID: 21732829.
      Citations: 73     Fields:    Translation:HumansCells
    78. Herrmann A, Haake A, Ammerpohl O, Martin-Guerrero I, Szafranski K, Stemshorn K, Nothnagel M, Kotsopoulos SK, Richter J, Warner J, Olson J, Link DR, Schreiber S, Krawczak M, Platzer M, Siebert R, Hampe J, N?rnberg P. Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors. PLoS One. 2011; 6(7):e21332. PMID: 21750708; PMCID: PMC3130030.
      Citations: 6     Fields:    Translation:HumansCells
    79. Nebel A, Kleindorp R, Caliebe A, Nothnagel M, Junge O, Wittig M, Ellinghaus D, Flachsbart F, Wichmann HE, Meitinger T, Nikolaus S, Franke A, Krawczak M, Lathrop M, Schreiber S, Blanch? H. A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals. Mech Ageing Dev. 2011 Jun-Jul; 132(6-7):324-30. PMID: 21740922.
      Citations: 111     Fields:    Translation:HumansCTClinical Trials
    80. Hofmann S, Fischer A, Till A, Franke A, Schaarschmidt H, Rosenstiel P, Nebel A, Nothnagel M, Schreiber S, GenPhenReSa Consortium, M?ller-Quernheim J, H?sler R, G?de KI, Sch?rmann M. A genome-wide association study reveals evidence of association with sarcoidosis at 6p12.1. Eur Respir J. 2011 Nov; 38(5):1127-35. PMID: 21540310.
      Citations: 23     Fields:    Translation:HumansCells
    81. Nothnagel M, Herrmann A, Wolf A, Schreiber S, Platzer M, Siebert R, Krawczak M, Hampe J. Technology-specific error signatures in the 1000 Genomes Project data. Hum Genet. 2011 Oct; 130(4):505-16. PMID: 21344269.
      Citations: 14     Fields:    Translation:Humans
    82. Nothnagel M, Wolf A, Herrmann A, Szafranski K, Vater I, Brosch M, Huse K, Siebert R, Platzer M, Hampe J, Krawczak M. Statistical inference of allelic imbalance from transcriptome data. Hum Mutat. 2011 Jan; 32(1):98-106. PMID: 21120951.
      Citations: 12     Fields:    Translation:HumansCells
    83. Thier S, Lorenz D, Nothnagel M, Nebel A, Christensen K, Schreiber S, Deuschl G, Klebe S, Kuhlenb?umer G. GABA(A) receptor- and GABA transporter polymorphisms and risk for essential tremor. Eur J Neurol. 2011 Aug; 18(8):1098-100. PMID: 21749575.
      Citations: 13     Fields:    Translation:Humans
    84. Schaefer AS, Richter GM, Dommisch H, Reinartz M, Nothnagel M, Noack B, Laine ML, Folwaczny M, Groessner-Schreiber B, Loos BG, Schreiber S, Jepsen S. CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection. J Med Genet. 2011 Jan; 48(1):38-47. PMID: 20978019.
      Citations: 26     Fields:    Translation:HumansCells
    85. Buch S, Schafmayer C, Seeger M, Miquel JF, Sookoian SC, Egberts JH, Arlt A, Pirola CJ, Lerch MM, John U, Franke A, von Kampen O, Brosch M, Nothnagel M, Kratzer W, Boehm BO, Schreiber S, Krawczak M, Hampe J, V?lzke H, Br?ring DC. Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition. Gastroenterology. 2010 Dec; 139(6):1942-1951.e2. PMID: 20837016.
      Citations: 36     Fields:    Translation:Humans
    86. Klebe S, Thier S, Lorenz D, Nothnagel M, Schreiber S, Klein C, Hagenah J, Kasten M, Berg D, Srulijes K, Gasser T, Deuschl G, Kuhlenb?umer G. LINGO1 is not associated with Parkinson's disease in German patients. Am J Med Genet B Neuropsychiatr Genet. 2010 Sep; 153B(6):1173-8. PMID: 20468067.
      Citations: 5     Fields:    Translation:Humans
    87. Nothnagel M, Franke A, Jacobs G, Saadati HR, Gaede KI, Rosenstiel P, Schreiber S, Hofmann S, Fischer A, Sch?rmann M, M?ller-Quernheim J. Association of inflammatory bowel disease risk loci with sarcoidosis, and its acute and chronic subphenotypes. Eur Respir J. 2011 Mar; 37(3):610-6. PMID: 20650992.
      Citations: 21     Fields:    Translation:Humans
    88. Nothnagel M, Lu TT, Kayser M, Krawczak M. Genomic and geographic distribution of SNP-defined runs of homozygosity in Europeans. Hum Mol Genet. 2010 Aug 01; 19(15):2927-35. PMID: 20462934.
      Citations: 77     Fields:    Translation:HumansCells
    89. Thier S, Lorenz D, Nothnagel M, Stevanin G, Nebel A, Schreiber S, Klebe S, D?rr A, Kuhlenb?umer G, Deuschl G. LINGO1 polymorphisms are associated with essential tremor in Europeans. Mov Disord. 2010 Apr 30; 25(6):717-23. PMID: 20310002.
      Citations: 20     Fields:    Translation:Humans
    90. Fischer A, Nothnagel M, Schreiber S, Hofmann S, Sch?rmann M, M?ller-Quernheim J. A genome-wide linkage analysis in 181 German sarcoidosis families using clustered biallelic markers. Chest. 2010 Jul; 138(1):151-7. PMID: 20190003.
      Citations: 4     Fields:    Translation:HumansCells
    91. Schaefer AS, Richter GM, Nothnagel M, Laine ML, Noack B, Glas J, Schrezenmeir J, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S. COX-2 is associated with periodontitis in Europeans. J Dent Res. 2010 Apr; 89(4):384-8. PMID: 20177132.
      Citations: 13     Fields:    Translation:Humans
    92. Nothnagel M, Krawczak M, Schmidtke J. Potentials and limits of pairwise kinship analysis using autosomal short tandem repeat loci. Int J Legal Med. 2010 May; 124(3):205-15. PMID: 20143081.
      Citations: 14     Fields:    Translation:HumansCells
    93. Rubin D, Helwig U, Nothnagel M, Schreiber S, F?lsch UR, Schrezenmeir J. Association of postprandial and fasting triglycerides with traits of the metabolic syndrome in the Metabolic Intervention Cohort Kiel. Eur J Endocrinol. 2010 Apr; 162(4):719-27. PMID: 20075144.
      Citations: 3     Fields:    Translation:Humans
    94. Flachsbart F, Caliebe A, Nothnagel M, Kleindorp R, Nikolaus S, Schreiber S, Nebel A. Depletion of potential A2M risk haplotype for Alzheimer's disease in long-lived individuals. Eur J Hum Genet. 2010 Jan; 18(1):59-61. PMID: 19639019; PMCID: PMC2987169.
      Citations: 3     Fields:    Translation:Humans
    95. Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma RK, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P, Stiehl A, Vermeire S, Beuers U, Manns MP, Schrumpf E, Boberg KM, Schreiber S, Weism?ller TJ. Genome-wide association analysis in primary sclerosing cholangitis. Gastroenterology. 2010 Mar; 138(3):1102-11. PMID: 19944697.
      Citations: 116     Fields:    Translation:HumansCells
    96. Schaefer AS, Richter GM, Nothnagel M, Manke T, Dommisch H, Jacobs G, Arlt A, Rosenstiel P, Noack B, Groessner-Schreiber B, Loos BG, Schreiber S, Jepsen S. A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis. Hum Mol Genet. 2010 Feb 01; 19(3):553-62. PMID: 19897590.
      Citations: 82     Fields:    Translation:HumansCells
    97. Schaefer AS, Richter GM, Nothnagel M, Laine ML, Cordes N, Noack B, Folwaczny M, Glas J, Dommisch H, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S, R?hling A, Sch?fer C, D?rfer C. A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis. Genes Immun. 2010 Jan; 11(1):45-54. PMID: 19829306.
      Citations: 26     Fields:    Translation:Humans
    98. Siddiqui RA, Sauermann U, Fritzer E, Nothnagel M, Dalibor N, Fellay J, Kaup FJ, Stahl-Hennig C, Krawczak M, Platzer M, Altm?ller J, N?rnberg P. X chromosomal variation is associated with slow progression to AIDS in HIV-1-infected women. Am J Hum Genet. 2009 Aug; 85(2):228-39. PMID: 19679225; PMCID: PMC2725232.
      Citations: 20     Fields:    Translation:HumansCells
    99. Nothnagel M, Parwez Q, Petrasch-Parwez E, Epplen JT, Hoffjan S, Stemmler S. Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients. Int J Immunogenet. 2009 Aug; 36(4):217-22. PMID: 19601998.
      Citations: 3     Fields:    Translation:HumansCells
    100. Loos BG, Fiebig A, Nothnagel M, Jepsen S, Groessner-Schreiber B, Franke A, Schenck K, van der Velden U, Schreiber S, Jerv?e-Storm PM. NOD1 gene polymorphisms in relation to aggressive periodontitis. Innate Immun. 2009 Aug; 15(4):225-32. PMID: 19587002.
      Citations: 1     Fields:    Translation:Humans
    101. Ellinghaus D, Schreiber S, Franke A, Nothnagel M. Current software for genotype imputation. Hum Genomics. 2009 Jul; 3(4):371-80. PMID: 19706367; PMCID: PMC3525198.
      Citations: 13     Fields:    
    102. Schaefer AS, Richter GM, Groessner-Schreiber B, Noack B, Nothnagel M, El Mokhtari NE, Loos BG, Schreiber S, Jepsen S. Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis. PLoS Genet. 2009 Feb; 5(2):e1000378. PMID: 19214202; PMCID: PMC2632758.
      Citations: 80     Fields:    Translation:HumansCells
    103. Lao O, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Nielsen F, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Gieger C, Wichmann HE, Ruether A, Schreiber S, Becker C, Nelson MR, Kayser M, Krawczak M, Lu TT, Uitterlinden AG, N?rnberg P. An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population. Eur J Hum Genet. 2009 Jul; 17(7):967-75. PMID: 19156175; PMCID: PMC2986489.
      Citations: 3     Fields:    Translation:Humans
    104. Helbig I, Mefford HC, Sharp AJ, Guipponi M, Fichera M, Franke A, Muhle H, de Kovel C, Baker C, von Spiczak S, Kron KL, Steinich I, Kleefuss-Lie AA, Leu C, Gaus V, Schmitz B, Klein KM, Reif PS, Rosenow F, Weber Y, Lerche H, Zimprich F, Urak L, Fuchs K, Feucht M, Genton P, Thomas P, Visscher F, de Haan GJ, Hjalgrim H, Luciano D, Wittig M, Nothnagel M, Elger CE, Romano C, Malafosse A, Koeleman BP, Lindhout D, Stephani U, Schreiber S, Eichler EE, Sander T, M?ller RS, N?rnberg P. 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy. Nat Genet. 2009 Feb; 41(2):160-2. PMID: 19136953; PMCID: PMC3026630.
      Citations: 226     Fields:    Translation:HumansCells
    105. Nothnagel M, Ellinghaus D, Schreiber S, Krawczak M, Franke A. A comprehensive evaluation of SNP genotype imputation. Hum Genet. 2009 Mar; 125(2):163-71. PMID: 19089453.
      Citations: 91     Fields:    Translation:Humans
    106. Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G, Domingues FS, Albrecht M, Nothnagel M, Ellinghaus D, Sina C, Onnie CM, Weersma RK, Stokkers PC, Wijmenga C, Gazouli M, Strachan D, McArdle WL, Rutgeerts P, Rosenstiel P, Krawczak M, Vatn MH, IBSEN study group, Mathew CG, Schreiber S, Vermeire S. Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet. 2008 Nov; 40(11):1319-23. PMID: 18836448.
      Citations: 260     Fields:    Translation:HumansCells
    107. Fiebig A, Loos BG, Scholz C, Nothnagel M, Eickholz P, van der Velden U, Schenck K, Schreiber S, Jepsen S, Sch?fer C, R?hling A, Gr?ssner-Schreiber B. Polymorphisms in the interleukin-1 (IL1) gene cluster are not associated with aggressive periodontitis in a large Caucasian population. Genomics. 2008 Nov; 92(5):309-15. PMID: 18723088.
      Citations: 8     Fields:    Translation:Humans
    108. Rubin D, Claas S, Pfeuffer M, Nothnagel M, Foelsch UR, Schrezenmeir J. s-ICAM-1 and s-VCAM-1 in healthy men are strongly associated with traits of the metabolic syndrome, becoming evident in the postprandial response to a lipid-rich meal. Lipids Health Dis. 2008 Sep 01; 7:32. PMID: 18761738; PMCID: PMC2543007.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    109. Hofmann S, Franke A, Fischer A, Jacobs G, Nothnagel M, Gaede KI, Krawczak M, Rosenstiel P, Schreiber S, Sch?rmann M, M?ller-Quernheim J. Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis. Nat Genet. 2008 Sep; 40(9):1103-6. PMID: 19165924.
      Citations: 99     Fields:    Translation:HumansCells
    110. Lao O, Lu TT, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Gieger C, Wichmann HE, Schreiber S, Becker C, Nelson MR, Krawczak M, Kayser M, Uitterlinden AG, R?ther A, N?rnberg P. Correlation between genetic and geographic structure in Europe. Curr Biol. 2008 Aug 26; 18(16):1241-8. PMID: 18691889.
      Citations: 209     Fields:    Translation:Humans
    111. Franke A, Fischer A, Nothnagel M, Becker C, Grabe N, Till A, Lu T, Wittig M, Hermann A, Balschun T, Hofmann S, Niemiec R, Schulz S, Hampe J, Nikolaus S, Krawczak M, Rosenstiel P, Nebel A, Schreiber S, M?ller-Quernheim J, N?rnberg P, Sch?rmann M. Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2. Gastroenterology. 2008 Oct; 135(4):1207-15. PMID: 18723019.
      Citations: 33     Fields:    Translation:HumansCells
    112. Nothnagel M, Lu TT, Krawczak M. Hypotheses in genome-wide association scans. Eur J Hum Genet. 2008 Oct; 16(10):1174-5; author reply 1175. PMID: 18478034.
      Citations: 1     Fields:    Translation:Humans
    113. Fischer A, Valentonyte R, Nebel A, Nothnagel M, Schreiber S, M?ller-Quernheim J, Sch?rmann M. Female-specific association of C-C chemokine receptor 5 gene polymorphisms with L?fgren's syndrome. J Mol Med (Berl). 2008 May; 86(5):553-61. PMID: 18311470.
      Citations: 8     Fields:    Translation:Humans
    114. El Mokhtari NE, Ott SJ, Nebel A, Rosenstiel P, Nothnagel M, Schreiber S, Sch?fer A, F?rster M, Simon R. Role of NOD2/CARD15 in coronary heart disease. BMC Genet. 2007 Nov 02; 8:76. PMID: 17980027; PMCID: PMC2204032.
      Citations: 6     Fields:    Translation:Humans
    115. Heckmann M, Holle JU, Arning L, Knaup S, Hellmich B, Nothnagel M, Jagiello P, Gross WL, Epplen JT, Wieczorek S. The Wegener's granulomatosis quantitative trait locus on chromosome 6p21.3 as characterised by tagSNP genotyping. Ann Rheum Dis. 2008 Jul; 67(7):972-9. PMID: 17967832.
      Citations: 31     Fields:    Translation:HumansCells
    116. Wollstein A, Herrmann A, Wittig M, Nothnagel M, Franke A, Schreiber S, Krawczak M, Hampe J, N?rnberg P. Efficacy assessment of SNP sets for genome-wide disease association studies. Nucleic Acids Res. 2007; 35(17):e113. PMID: 17726055; PMCID: PMC2034459.
      Citations: 5     Fields:    Translation:Humans
    117. Macaluso F, Nothnagel M, Parwez Q, Petrasch-Parwez E, Bechara FG, Epplen JT, Hoffjan S. Polymorphisms in NACHT-LRR (NLR) genes in atopic dermatitis. Exp Dermatol. 2007 Aug; 16(8):692-8. PMID: 17620097.
      Citations: 50     Fields:    Translation:Humans
    118. Rubin D, Helwig U, Nothnagel M, Lemke N, Schreiber S, F?lsch UR, D?ring F, Schrezenmeir J. Postprandial plasma adiponectin decreases after glucose and high fat meal and is independently associated with postprandial triacylglycerols but not with -- 11388 promoter polymorphism. Br J Nutr. 2008 Jan; 99(1):76-82. PMID: 17663805.
      Citations: 10     Fields:    Translation:HumansCells
    119. Helwig U, Rubin D, Klapper M, Li Y, Nothnagel M, Schreiber S, F?lsch UR, D?ring F, Schrezenmeir J. The association of fatty acid-binding protein 2 A54T polymorphism with postprandial lipemia depends on promoter variability. Metabolism. 2007 Jun; 56(6):723-31. PMID: 17512303.
      Citations: 3     Fields:    Translation:HumansCells
    120. Helwig U, Rubin D, Kiosz J, Schreiber S, Nothnagel M, F?lsch UR, D?ring F, Schrezenmeir J. The minor allele of the PPARgamma2 pro12Ala polymorphism is associated with lower postprandial TAG and insulin levels in non-obese healthy men. Br J Nutr. 2007 May; 97(5):847-54. PMID: 17408525.
      Citations: 8     Fields:    Translation:Humans
    121. Nothnagel M, Wollstein A, Krawczak M. Comparative assessment of the association information captured by SNP tagging. Hum Hered. 2007; 64(1):27-34. PMID: 17483594.
      Citations: 1     Fields:    Translation:HumansCells
    122. Nebel A, Flachsbart F, Nothnagel M, Nikolaus S, Mokhtari NE, Schreiber S, Sch?fer A. Role of the toll-like receptor 4 polymorphism Asp299Gly in longevity and myocardial infarction in German men. Mech Ageing Dev. 2007 May-Jun; 128(5-6):409-11. PMID: 17493663.
      Citations: 9     Fields:    Translation:Humans
    123. Schimming TT, Parwez Q, Petrasch-Parwez E, Nothnagel M, Epplen JT, Hoffjan S. Association of toll-interacting protein gene polymorphisms with atopic dermatitis. BMC Dermatol. 2007 Mar 16; 7:3. PMID: 17362526; PMCID: PMC1832210.
      Citations: 13     Fields:    Translation:Humans
    124. Hoffjan S, Parwez Q, Petrasch-Parwez E, Falkenstein D, Nothnagel M, Epplen JT. Association screen for atopic dermatitis candidate gene regions using microsatellite markers in pooled DNA samples. Int J Immunogenet. 2006 Dec; 33(6):401-9. PMID: 17117949.
      Citations: 2     Fields:    Translation:HumansCells
    125. Rohde K, Nothnagel M. The effect of single-nucleotide polymorphism marker selection on patterns of haplotype blocks and haplotype frequency estimates. Am J Hum Genet. 2005 Dec; 77(6):988-98. PMID: 16380910; PMCID: PMC1285181.
      Citations: 11     Fields:    Translation:Humans
    126. Nothnagel M, Ott J. Statistical gene mapping of traits in humans--hypertension as a complex trait: is it amenable to genetic analysis? Semin Nephrol. 2002 Mar; 22(2):105-14. PMID: 11891504.
      Citations: 1     Fields:    Translation:Humans
    127. Rohde K, Nothnagel M, F?rst R. Entropy as a measure for linkage disequilibrium over multilocus haplotype blocks. Hum Hered. 2002; 54(4):186-98. PMID: 12771551.
      Citations: 26     Fields:    Translation:Humans
    128. Schuster H, Lamprecht A, Junghans C, Dietz B, Baron H, Nothnagel M, Luft FC, M?ller-Myhsok B. Approaches to the genetics of cardiovascular disease through genetic field work. Kidney Int. 1998 Jun; 53(6):1449-54. PMID: 9607173.
      Citations:    Fields:    Translation:Humans

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