"Calgranulin B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 13.2-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN A and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin B is expressed at high concentrations in GRANULOCYTES during early monocyte differentiation, and serum calgranulin B levels are elevated in many inflammatory disorders such as CYSTIC FIBROSIS.
| Descriptor ID |
D040502
|
| MeSH Number(s) |
D12.776.157.125.750.500.200 D12.776.631.655.500.200 D23.050.301.562.200
|
| Concept/Terms |
Calgranulin B- Calgranulin B
- CABP-P14
- MRP14 Protein
- Leukocyte L1 Protein Heavy Chain
- Antigen 60B8-A
- Antigen 60B8 A
- Macrophage-Related Protein-14
- Macrophage Related Protein 14
- Myeloid Calcium-Binding Protein p14
- Myeloid Calcium Binding Protein p14
- MRP-14 Protein
- MRP 14 Protein
- 60B8-A Antigen
- 60B8 A Antigen
- Antigen, 60B8-A
- S100A9 Protein
|
Below are MeSH descriptors whose meaning is more general than "Calgranulin B".
Below are MeSH descriptors whose meaning is more specific than "Calgranulin B".
This graph shows the total number of publications written about "Calgranulin B" by people in this website by year, and whether "Calgranulin B" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Calgranulin B" by people in Profiles.
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S100A8/A9 is the first predictive marker for neonatal sepsis. Clin Transl Med. 2021 04; 11(4):e338.
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S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants. Gastroenterology. 2020 12; 159(6):2130-2145.e5.
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Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis. Gut. 2020 03; 69(3):551-563.
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Impaired cellular energy metabolism in cord blood macrophages contributes to abortive response toward inflammatory threats. Nat Commun. 2019 04 11; 10(1):1685.
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Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018 05 01; 128(5):1852-1866.
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S100-alarmin-induced innate immune programming protects newborn infants from sepsis. Nat Immunol. 2017 06; 18(6):622-632.
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In neonates S100A8/S100A9 alarmins prevent the expansion of a specific inflammatory monocyte population promoting septic shock. FASEB J. 2017 03; 31(3):1153-1164.
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Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions. Cell Rep. 2014 Dec 24; 9(6):2112-23.
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Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8. J Immunol. 2015 Jan 15; 194(2):575-83.
MeSH information
