"Macrophage Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.
Descriptor ID |
D008262
|
MeSH Number(s) |
G12.287.500
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Concept/Terms |
Macrophage Activation- Macrophage Activation
- Activation, Macrophage
- Activations, Macrophage
- Macrophage Activations
|
Below are MeSH descriptors whose meaning is more general than "Macrophage Activation".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Activation".
This graph shows the total number of publications written about "Macrophage Activation" by people in this website by year, and whether "Macrophage Activation" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2014 | 2 | 0 | 2 |
2015 | 2 | 2 | 4 |
2016 | 2 | 1 | 3 |
2017 | 1 | 1 | 2 |
2018 | 1 | 1 | 2 |
2019 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
2021 | 1 | 1 | 2 |
2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Macrophage Activation" by people in Profiles.
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A common framework of monocyte-derived macrophage activation. Sci Immunol. 2022 04 15; 7(70):eabl7482.
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Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF. Life Sci Alliance. 2022 04; 5(4).
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Cannabinoid receptor 2 is necessary to induce toll-like receptor-mediated microglial activation. Glia. 2022 01; 70(1):71-88.
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Soluble mannose receptor induces proinflammatory macrophage activation and metaflammation. Proc Natl Acad Sci U S A. 2021 08 03; 118(31).
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CD163 expression defines specific, IRF8-dependent, immune-modulatory macrophages in the bone marrow. J Allergy Clin Immunol. 2020 11; 146(5):1137-1151.
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Autophagy differentially regulates macrophage lipid handling depending on the lipid substrate (oleic acid vs. acetylated-LDL) and inflammatory activation state. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 12; 1864(12):158527.
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Reprogramming of pro-inflammatory human macrophages to an anti-inflammatory phenotype by bile acids. Sci Rep. 2018 01 10; 8(1):255.
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Bioinformatic Assessment of Macrophage Activation by the Innate Immune System. Methods Mol Biol. 2018; 1714:19-40.
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Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2. Immunity. 2017 12 19; 47(6):1051-1066.e12.
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New "programmers" in tissue macrophage activation. Pflugers Arch. 2017 04; 469(3-4):375-383.