"Guanine Nucleotide Exchange Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS.
Descriptor ID |
D020662
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MeSH Number(s) |
D12.644.360.325.300 D12.776.476.325.300
|
Concept/Terms |
Guanine Nucleotide Exchange Factors- Guanine Nucleotide Exchange Factors
- Guanine-Nucleotide-Releasing Factor
- Guanine Nucleotide Releasing Factor
- GDP Dissociation Factor
- GDP-GTP Exchange Protein
- GDP GTP Exchange Protein
- GDP Dissociation Stimulators
- GDP-GTP Reversing Factors
- Factors, GDP-GTP Reversing
- GDP GTP Reversing Factors
- Reversing Factors, GDP-GTP
- Guanine Nucleotide Releasing Factors
- GDP Exchange Factors
- Exchange Factors, GDP
- Factors, GDP Exchange
- Guanine Nucleotide Exchange Factor
|
Below are MeSH descriptors whose meaning is more general than "Guanine Nucleotide Exchange Factors".
Below are MeSH descriptors whose meaning is more specific than "Guanine Nucleotide Exchange Factors".
This graph shows the total number of publications written about "Guanine Nucleotide Exchange Factors" by people in this website by year, and whether "Guanine Nucleotide Exchange Factors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2014 | 0 | 2 | 2 |
2015 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanine Nucleotide Exchange Factors" by people in Profiles.
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Expanding the spectrum of EEF1D neurodevelopmental disorders: Biallelic variants in the guanine exchange domain. Clin Genet. 2023 04; 103(4):484-491.
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Genome-wide interaction study with major depression identifies novel variants associated with cognitive function. Mol Psychiatry. 2022 02; 27(2):1111-1119.
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Biallelic MADD variants cause a phenotypic spectrum ranging from developmental delay to a multisystem disorder. Brain. 2020 08 01; 143(8):2437-2453.
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The genomic and clinical landscape of fetal akinesia. Genet Med. 2020 03; 22(3):511-523.
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Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. Nat Commun. 2016 07 01; 7:12050.
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Mutational dynamics between primary and relapse neuroblastomas. Nat Genet. 2015 Aug; 47(8):872-7.
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Haploidentical stem cell transplantation in DOCK8 deficiency - Successful control of pre-existing severe viremia with a TCRa?/CD19-depleted graft and antiviral treatment. Clin Immunol. 2014 May-Jun; 152(1-2):111-4.
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A genome-wide association study of anorexia nervosa. Mol Psychiatry. 2014 Oct; 19(10):1085-94.
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Expanding the phenotype of IQSEC2 mutations: truncating mutations in severe intellectual disability. Eur J Hum Genet. 2014 Feb; 22(2):289-92.
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Treosulfan-based conditioning in DOCK8 deficiency: complete lympho-hematopoietic reconstitution with minimal toxicity. Clin Immunol. 2012 Dec; 145(3):259-61.