"Mast Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
Descriptor ID |
D008407
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MeSH Number(s) |
A11.329.427 A15.382.652
|
Concept/Terms |
Mast Cells- Mast Cells
- Cell, Mast
- Cells, Mast
- Mast Cell
- Basophils, Tissue
- Basophil, Tissue
- Tissue Basophil
- Tissue Basophils
|
Below are MeSH descriptors whose meaning is more general than "Mast Cells".
Below are MeSH descriptors whose meaning is more specific than "Mast Cells".
This graph shows the total number of publications written about "Mast Cells" by people in this website by year, and whether "Mast Cells" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2013 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
2023 | 1 | 2 | 3 |
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Below are the most recent publications written about "Mast Cells" by people in Profiles.
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Mast cell deficiency prevents BCR::ABL1 induced splenomegaly and cytokine elevation in a CML mouse model. Leukemia. 2023 07; 37(7):1474-1484.
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Transformation of primary murine peritoneal mast cells by constitutive KIT activation is accompanied by loss of Cdkn2a/Arf expression. Front Immunol. 2023; 14:1154416.
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KIT D816V Mast Cells Derived from Induced Pluripotent Stem Cells Recapitulate Systemic Mastocytosis Transcriptional Profile. Int J Mol Sci. 2023 Mar 09; 24(6).
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Higher Mast Cell Accumulation in Human Adipose Tissues Defines Clinically Favorable Obesity Sub-Phenotypes. Cells. 2020 06 20; 9(6).
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Mast cell activation in Dowling-Degos disease. Br J Dermatol. 2019 12; 181(6):1312-1314.
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Although Abundant in Tumor Tissue, Mast Cells Have No Effect on Immunological Micro-milieu or Growth of HPV-Induced or Transplanted Tumors. Cell Rep. 2018 01 02; 22(1):27-35.
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The Neurobeachin-like 2 Protein Regulates Mast Cell Homeostasis. J Immunol. 2017 10 15; 199(8):2948-2957.
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MK2/3 Are Pivotal for IL-33-Induced and Mast Cell-Dependent Leukocyte Recruitment and the Resulting Skin Inflammation. J Immunol. 2016 11 01; 197(9):3662-3668.
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Evidence for contribution of epigenetic mechanisms in the pathogenesis of systemic mast cell activation disease. Immunogenetics. 2014 May; 66(5):287-97.
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The transcriptome of the human mast cell leukemia cells HMC-1.2: an approach to identify specific changes in the gene expression profile in KitD816V systemic mastocytosis. Immunol Res. 2013 May; 56(1):155-62.