Next Generation Sequencing Competence Network

Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES), conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES), and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES).

Descriptor ID	D043743
MeSH Number(s)	D08.811.464.938
Concept/Terms	Ubiquitin-Protein Ligase Complexes Ubiquitin-Protein Ligase Complexes Complexes, Ubiquitin-Protein Ligase Ligase Complexes, Ubiquitin-Protein Ubiquitin Protein Ligase Complexes

Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Protein Ligase Complexes".

Below are MeSH descriptors whose meaning is related to "Ubiquitin-Protein Ligase Complexes".

Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Protein Ligase Complexes".