"Neuroprotective Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Descriptor ID |
D018696
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MeSH Number(s) |
D27.505.696.706.548 D27.505.954.427.575
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Concept/Terms |
Neuroprotective Agents- Neuroprotective Agents
- Agents, Neuroprotective
- Neuroprotectants
- Neuroprotective Drugs
- Drugs, Neuroprotective
Neuroprotective Effect- Neuroprotective Effect
- Effect, Neuroprotective
- Neuroprotective Effects
- Effects, Neuroprotective
|
Below are MeSH descriptors whose meaning is more general than "Neuroprotective Agents".
Below are MeSH descriptors whose meaning is more specific than "Neuroprotective Agents".
This graph shows the total number of publications written about "Neuroprotective Agents" by people in this website by year, and whether "Neuroprotective Agents" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2006 | 1 | 1 | 2 |
2009 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neuroprotective Agents" by people in Profiles.
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Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease. Sci Transl Med. 2016 10 26; 8(362):362ra146.
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Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst. J Neurosci. 2013 Nov 13; 33(46):18270-6.
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Mitochondrial involvement in temporal lobe epilepsy. Exp Neurol. 2009 Aug; 218(2):326-32.
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Amelioration of water maze performance deficits by topiramate applied during pilocarpine-induced status epilepticus is negatively dose-dependent. Epilepsy Res. 2007 Feb; 73(2):173-80.
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Binding of copper is a mechanism of homocysteine toxicity leading to COX deficiency and apoptosis in primary neurons, PC12 and SHSY-5Y cells. Neurobiol Dis. 2006 Sep; 23(3):725-30.
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The mechanism of neuroprotection by topiramate in an animal model of epilepsy. Epilepsia. 2004 Dec; 45(12):1478-87.