"CD3 Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).
Descriptor ID |
D017252
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MeSH Number(s) |
D23.050.301.264.894.095 D23.101.100.894.095
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Concept/Terms |
CD3 Complex- CD3 Complex
- T3 Antigens
- Antigens, T3
- T3 Complex
- CD3 Antigens
- Antigens, CD3
- T3 Antigen
- Antigen, T3
- CD3 Antigen
- Antigen, CD3
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Below are MeSH descriptors whose meaning is more general than "CD3 Complex".
Below are MeSH descriptors whose meaning is more specific than "CD3 Complex".
This graph shows the total number of publications written about "CD3 Complex" by people in this website by year, and whether "CD3 Complex" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2003 | 1 | 0 | 1 |
2006 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD3 Complex" by people in Profiles.
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iNKT cell frequency in peripheral blood of Caucasian children and adolescent: the absolute iNKT cell count is stable from birth to adulthood. Scand J Immunol. 2011 Oct; 74(4):406-11.
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The immune protein CD3zeta is required for normal development of neural circuits in the retina. Neuron. 2010 Feb 25; 65(4):503-15.
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Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection. J Clin Invest. 2006 Dec; 116(12):3160-70.
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The bi-specific CD3 x NCAM antibody: a model to preactivate T cells prior to tumour cell lysis. Clin Exp Immunol. 2003 Nov; 134(2):253-63.
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Ontogeny recapitulates phylogeny: comparative immunology in Germany. Exp Clin Immunogenet. 2000; 17(2):77-82.