"Superoxides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
Descriptor ID |
D013481
|
MeSH Number(s) |
D01.248.497.158.685.750.850 D01.339.431.374.850 D01.650.550.750.800 D02.389.338.732
|
Concept/Terms |
Superoxides- Superoxides
- Superoxide Anion
- Superoxide Radical
- Superoxide
|
Below are MeSH descriptors whose meaning is more general than "Superoxides".
Below are MeSH descriptors whose meaning is more specific than "Superoxides".
This graph shows the total number of publications written about "Superoxides" by people in this website by year, and whether "Superoxides" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 |
2006 | 1 | 1 | 2 |
2008 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2014 | 0 | 2 | 2 |
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Below are the most recent publications written about "Superoxides" by people in Profiles.
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An acute rise in intraluminal pressure shifts the mediator of flow-mediated dilation from nitric oxide to hydrogen peroxide in human arterioles. Am J Physiol Heart Circ Physiol. 2014 Dec 01; 307(11):H1587-93.
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Roothairless5, which functions in maize (Zea mays L.) root hair initiation and elongation encodes a monocot-specific NADPH oxidase. Plant J. 2014 Sep; 79(5):729-40.
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Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation. Biochim Biophys Acta. 2010 Jun-Jul; 1797(6-7):1163-70.
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Chapter 23 Quantification of superoxide production by mouse brain and skeletal muscle mitochondria. Methods Enzymol. 2009; 456:419-37.
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Sites of generation of reactive oxygen species in homogenates of brain tissue determined with the use of respiratory substrates and inhibitors. Biochim Biophys Acta. 2008 Jul-Aug; 1777(7-8):689-95.
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Human epidermal keratinocytes accumulate superoxide due to low activity of Mn-SOD, leading to mitochondrial functional impairment. J Invest Dermatol. 2007 May; 127(5):1084-93.
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Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6. Neurobiol Dis. 2007 Feb; 25(2):401-11.
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Characterization of superoxide-producing sites in isolated brain mitochondria. J Biol Chem. 2004 Feb 06; 279(6):4127-35.