"Immunoglobulins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.
Descriptor ID |
D007136
|
MeSH Number(s) |
D12.776.124.486.485 D12.776.124.790.651 D12.776.377.715.548
|
Concept/Terms |
Immunoglobulins- Immunoglobulins
- Immunoglobulin
- Globulins, Immune
- Immune Globulins
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulins".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulins".
This graph shows the total number of publications written about "Immunoglobulins" by people in this website by year, and whether "Immunoglobulins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 1 | 1 | 2 |
2009 | 0 | 1 | 1 |
2012 | 0 | 2 | 2 |
2015 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulins" by people in Profiles.
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CD83 expression is essential for Treg cell differentiation and stability. JCI Insight. 2018 06 07; 3(11).
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Infectious and immunologic phenotype of MECP2 duplication syndrome. J Clin Immunol. 2015 Feb; 35(2):168-81.
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Minimal residual disease after induction is the strongest predictor of prognosis in intermediate risk relapsed acute lymphoblastic leukaemia - long-term results of trial ALL-REZ BFM P95/96. Eur J Cancer. 2013 Apr; 49(6):1346-55.
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Fatal outcome despite full lympho-hematopoietic reconstitution after allogeneic stem cell transplantation in atypical ataxia telangiectasia. J Clin Immunol. 2012 Jun; 32(3):438-40.
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Reassessment of treatment modalities for paediatric patients with chronic immune thrombocytopenia. Hamostaseologie. 2009 May; 29(2):171-6.
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Two different epitopes of the signal transducer gp130 sequentially cooperate on IL-6-induced receptor activation. J Immunol. 2000 Dec 15; 165(12):7042-9.
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Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies. Nat Med. 2000 Jun; 6(6):667-72.