"Oligomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).
Descriptor ID |
D009840
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MeSH Number(s) |
D02.540.505.620
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oligomycins".
Below are MeSH descriptors whose meaning is more specific than "Oligomycins".
This graph shows the total number of publications written about "Oligomycins" by people in this website by year, and whether "Oligomycins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oligomycins" by people in Profiles.
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Application of inhibitor titrations for the detection of oxidative phosphorylation defects in saponin-skinned muscle fibers of patients with mitochondrial diseases. Biochim Biophys Acta. 1997 Apr 12; 1360(2):142-50.
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Phosphate affects the distribution of flux control among the enzymes of oxidative phosphorylation in rat skeletal muscle mitochondria. J Biol Chem. 1993 May 05; 268(13):9343-6.
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Long-chain fatty acids act as protonophoric uncouplers of oxidative phosphorylation in rat liver mitochondria. Biochim Biophys Acta. 1989 Dec 07; 977(3):266-72.
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On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. Biochim Biophys Acta. 1988 Dec 07; 936(3):280-8.
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Control of oxidative phosphorylation by the extra-mitochondrial ATP/ADP ratio. Biochim Biophys Acta. 1976 Aug 13; 440(2):391-402.
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[On the energy-linked ion translocation through the mitochondrial membrane]. Acta Biol Med Ger. 1967; 19(5):766-79.