"Muscle Spasticity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a "free interval") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
Descriptor ID |
D009128
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MeSH Number(s) |
C05.651.512 C10.597.613.550.550 C23.888.592.608.550.550
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Muscle Spasticity".
Below are MeSH descriptors whose meaning is more specific than "Muscle Spasticity".
This graph shows the total number of publications written about "Muscle Spasticity" by people in this website by year, and whether "Muscle Spasticity" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Muscle Spasticity" by people in Profiles.
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Heterozygous UCHL1 loss-of-function variants cause a neurodegenerative disorder with spasticity, ataxia, neuropathy, and optic atrophy. Genet Med. 2022 10; 24(10):2079-2090.
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Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia. Brain. 2017 06 01; 140(6):1561-1578.
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Effective treatment of spasticity using dronabinol in pediatric palliative care. Eur J Paediatr Neurol. 2016 Nov; 20(6):898-903.
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Phenotypic characterization of hypomyelination and congenital cataract. Ann Neurol. 2007 Aug; 62(2):121-7.