"Patch-Clamp Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
Descriptor ID |
D018408
|
MeSH Number(s) |
E05.200.500.905 E05.242.800
|
Concept/Terms |
Patch-Clamp Techniques- Patch-Clamp Techniques
- Patch Clamp Techniques
- Patch-Clamp Technique
- Technique, Patch-Clamp
- Techniques, Patch-Clamp
- Patch-Clamp Technics
- Patch Clamp Technics
- Patch-Clamp Technic
- Technic, Patch-Clamp
- Technics, Patch-Clamp
Whole-Cell Recording- Whole-Cell Recording
- Recording, Whole-Cell
- Recordings, Whole-Cell
- Whole Cell Recording
- Whole-Cell Recordings
Voltage-Clamp Techniques- Voltage-Clamp Techniques
- Technique, Voltage-Clamp
- Techniques, Voltage-Clamp
- Voltage Clamp Techniques
- Voltage-Clamp Technique
- Voltage-Clamp Technics
- Technic, Voltage-Clamp
- Technics, Voltage-Clamp
- Voltage Clamp Technics
- Voltage-Clamp Technic
|
Below are MeSH descriptors whose meaning is more general than "Patch-Clamp Techniques".
Below are MeSH descriptors whose meaning is more specific than "Patch-Clamp Techniques".
This graph shows the total number of publications written about "Patch-Clamp Techniques" by people in this website by year, and whether "Patch-Clamp Techniques" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2013 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Patch-Clamp Techniques" by people in Profiles.
-
Assessing the impact of pain-linked Nav1.7 variants: An example of two variants with no biophysical effect. Channels (Austin). 2021 12; 15(1):208-228.
-
DNA Methylation-Mediated Modulation of Endocytosis as Potential Mechanism for Synaptic Function Regulation in Murine Inhibitory Cortical Interneurons. Cereb Cortex. 2020 06 01; 30(7):3921-3937.
-
Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features. Brain. 2017 Nov 01; 140(11):2879-2894.
-
Hemin inhibits the large conductance potassium channel in brain mitochondria: a putative novel mechanism of neurodegeneration. Exp Neurol. 2014 Jul; 257:70-5.
-
A modular gain-of-function approach to generate cortical interneuron subtypes from ES cells. Neuron. 2013 Dec 04; 80(5):1145-58.