"Ribonucleoprotein, U5 Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U5 snRNP along with U4-U6 snRNP preassemble into a single 25S particle that binds to the U1 and U2 snRNPs and the substrate to form SPLICEOSOMES.
| Descriptor ID |
D017415
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| MeSH Number(s) |
D12.776.157.725.500.875.620 D12.776.157.725.829.375 D12.776.664.962.500.875.620 D12.776.664.962.829.375
|
| Concept/Terms |
Ribonucleoprotein, U5 Small Nuclear- Ribonucleoprotein, U5 Small Nuclear
- Small Nuclear Ribonucleoproteins, U5
- Ribonucleoproteins, Small, U5
- U5 snRNP
- U5 Small Nuclear Ribonucleoproteins
|
Below are MeSH descriptors whose meaning is more general than "Ribonucleoprotein, U5 Small Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Ribonucleoprotein, U5 Small Nuclear".
This graph shows the total number of publications written about "Ribonucleoprotein, U5 Small Nuclear" by people in this website by year, and whether "Ribonucleoprotein, U5 Small Nuclear" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ribonucleoprotein, U5 Small Nuclear" by people in Profiles.
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Ecd promotes U5 snRNP maturation and Prp8 stability. Nucleic Acids Res. 2021 02 22; 49(3):1688-1707.
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Identification of causative variants in TXNL4A in Burn-McKeown syndrome and isolated choanal atresia. Eur J Hum Genet. 2017 10; 25(10):1126-1133.
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TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes. PLoS Genet. 2017 03; 13(3):e1006660.
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Compound heterozygosity of low-frequency promoter deletions and rare loss-of-function mutations in TXNL4A causes Burn-McKeown syndrome. Am J Hum Genet. 2014 Dec 04; 95(6):698-707.
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Oto-facial syndrome and esophageal atresia, intellectual disability and zygomatic anomalies - expanding the phenotypes associated with EFTUD2 mutations. Orphanet J Rare Dis. 2013 Jul 24; 8:110.
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Haploinsufficiency of a spliceosomal GTPase encoded by EFTUD2 causes mandibulofacial dysostosis with microcephaly. Am J Hum Genet. 2012 Feb 10; 90(2):369-77.
MeSH information
