"Proto-Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Normal cellular genes homologous to viral oncogenes. The products of proto-oncogenes are important regulators of biological processes and appear to be involved in the events that serve to maintain the ordered procession through the cell cycle. Proto-oncogenes have names of the form c-onc.
Descriptor ID |
D011519
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MeSH Number(s) |
G05.360.340.024.340.375.500.791
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogenes".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogenes".
- Proto-Oncogenes
- Genes, abl
- Genes, bcl-1
- Genes, bcl-2
- Genes, erbA
- Genes, erbB
- Genes, fms
- Genes, fos
- Genes, jun
- Genes, mos
- Genes, myb
- Genes, myc
- Genes, ras
- Genes, rel
- Genes, sis
- Genes, src
This graph shows the total number of publications written about "Proto-Oncogenes" by people in this website by year, and whether "Proto-Oncogenes" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1995 | 2 | 0 | 2 |
1997 | 1 | 0 | 1 |
1998 | 1 | 0 | 1 |
2000 | 1 | 0 | 1 |
2001 | 1 | 0 | 1 |
2003 | 2 | 0 | 2 |
2005 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogenes" by people in Profiles.
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Prominent Oncogenic Roles of EVI1 in Breast Carcinoma. Cancer Res. 2017 04 15; 77(8):2148-2160.
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Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5). Genes Chromosomes Cancer. 2005 Aug; 43(4):424-6.
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Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides. Genes Chromosomes Cancer. 2003 Apr; 36(4):393-401.
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The human LASP1 gene is fused to MLL in an acute myeloid leukemia with t(11;17)(q23;q21). Oncogene. 2003 Jan 09; 22(1):157-60.
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The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8756-61.
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The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q. Proc Natl Acad Sci U S A. 2000 Aug 01; 97(16):9168-73.
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A new fingerprint method for sequence analysis of chromosomal translocations at the genomic DNA level. Leukemia. 1998 May; 12(5):758-63.
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Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23). Oncogene. 1997 Jan 16; 14(2):195-202.
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Rapid synthesis of hybrid RNA molecules associated with leukemia-specific chromosomal translocations. Leukemia. 1995 Apr; 9(4):719-22.
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Secondary acute myeloid leukemia with translocation (4;11) and MLL/AF4 rearrangement in a 15-year-old boy treated for common acute lymphoblastic leukemia 11 years earlier. Ann Hematol. 1995 Jan; 70(1):31-5.