"Optic Atrophy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition.
| Descriptor ID |
D009896
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| MeSH Number(s) |
C10.292.700.225 C11.640.451
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Optic Atrophy".
Below are MeSH descriptors whose meaning is more specific than "Optic Atrophy".
This graph shows the total number of publications written about "Optic Atrophy" by people in this website by year, and whether "Optic Atrophy" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Optic Atrophy" by people in Profiles.
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Heterozygous UCHL1 loss-of-function variants cause a neurodegenerative disorder with spasticity, ataxia, neuropathy, and optic atrophy. Genet Med. 2022 10; 24(10):2079-2090.
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Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration. Brain. 2020 01 01; 143(1):94-111.
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Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia. Brain. 2017 06 01; 140(6):1561-1578.
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A novel OPA3 mutation revealed by exome sequencing: an example of reverse phenotyping. JAMA Neurol. 2013 Jun; 70(6):783-7.
MeSH information
