"Exodeoxyribonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the exonucleolytic cleavage of DNA. It includes members of the class EC 3.1.11 that produce 5'-phosphomonoesters as cleavage products.
Descriptor ID |
D005090
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MeSH Number(s) |
D08.811.277.352.335.375 D08.811.277.352.365.290
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Exodeoxyribonucleases".
Below are MeSH descriptors whose meaning is more specific than "Exodeoxyribonucleases".
This graph shows the total number of publications written about "Exodeoxyribonucleases" by people in this website by year, and whether "Exodeoxyribonucleases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2014 | 2 | 0 | 2 |
2016 | 1 | 1 | 2 |
2018 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Exodeoxyribonucleases" by people in Profiles.
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Replication fork rescue in mammalian mitochondria. Sci Rep. 2019 06 19; 9(1):8785.
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Linear mitochondrial DNA is rapidly degraded by components of the replication machinery. Nat Commun. 2018 04 30; 9(1):1727.
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Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity. J Immunol. 2016 09 15; 197(6):2157-66.
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RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA. Nat Commun. 2016 05 27; 7:11752.
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Atypical Aicardi-Goutieres syndrome: is the WRN locus a modifier? Am J Med Genet A. 2014 Oct; 164A(10):2510-3.
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Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease. Hum Mol Genet. 2014 Dec 01; 23(23):6147-62.
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Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease. Nat Genet. 2013 Feb; 45(2):214-9.
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Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Gouti?res syndrome. Arthritis Rheum. 2010 May; 62(5):1469-77.