"Acid Ceramidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.
| Descriptor ID |
D055573
|
| MeSH Number(s) |
D08.811.277.087.250.100
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acid Ceramidase".
Below are MeSH descriptors whose meaning is more specific than "Acid Ceramidase".
This graph shows the total number of publications written about "Acid Ceramidase" by people in this website by year, and whether "Acid Ceramidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acid Ceramidase" by people in Profiles.
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Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease. Nat Commun. 2020 03 12; 11(1):1338.
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Altered lipid metabolism in the aging kidney identified by three layered omic analysis. Aging (Albany NY). 2016 Mar; 8(3):441-57.
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Acid ceramidase is associated with an improved prognosis in both DCIS and invasive breast cancer. Mol Oncol. 2015 Jan; 9(1):58-67.
MeSH information
