"Potassium Channel Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
| Descriptor ID |
D026902
|
| MeSH Number(s) |
D27.505.519.562.500 D27.505.954.411.645
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Potassium Channel Blockers".
Below are MeSH descriptors whose meaning is more specific than "Potassium Channel Blockers".
This graph shows the total number of publications written about "Potassium Channel Blockers" by people in this website by year, and whether "Potassium Channel Blockers" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Potassium Channel Blockers" by people in Profiles.
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Hemin inhibits the large conductance potassium channel in brain mitochondria: a putative novel mechanism of neurodegeneration. Exp Neurol. 2014 Jul; 257:70-5.
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Calcium ions regulate K? uptake into brain mitochondria: the evidence for a novel potassium channel. Int J Mol Sci. 2009 Mar; 10(3):1104-20.
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Mitochondrial potassium channels. IUBMB Life. 2009 Feb; 61(2):134-43.
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BK channel openers inhibit ROS production of isolated rat brain mitochondria. Exp Neurol. 2008 Aug; 212(2):543-7.
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Mitochondrial potassium channels: from pharmacology to function. Biochim Biophys Acta. 2006 May-Jun; 1757(5-6):715-20.
MeSH information
